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Volumn 4, Issue 3, 2015, Pages 1-9

An immunogenomic stratification of colorectal cancer: Implications for development of targeted immunotherapy

Author keywords

Colorectal cancer; Immune signature; Microsatellite instability; RAS; Stratification

Indexed keywords

B RAF KINASE; K RAS PROTEIN; RAS PROTEIN;

EID: 84942824207     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.4161/2162402X.2014.976052     Document Type: Article
Times cited : (87)

References (46)
  • 1
    • 33749319703 scopus 로고    scopus 로고
    • Type, Density, and Location of immune cells within human colorectal tumors predict clinical outcome
    • PMID:17008531
    • Galon J. Type, Density, and Location of immune cells within human colorectal tumors predict clinical outcome. Science 2006; 313:1960-4; PMID:17008531; http://dx.doi.org/10.1126/science.1129139
    • (2006) Science , vol.313 , pp. 1960-1964
    • Galon, J.1
  • 6
    • 4344590375 scopus 로고    scopus 로고
    • Different gene expression profiles between microsatellite instability-high and microsatellite stable colorectal carcinomas
    • PMID:15208663
    • Kim H, Nam SW, Rhee H, Shan Li L, Ju Kang H, Hye Koh K, Kyu Kim N, Song J, Tak-Bun Liu E, Kim H. Different gene expression profiles between microsatellite instability-high and microsatellite stable colorectal carcinomas. Oncogene 2004; 23:6218-25; PMID:15208663; http://dx.doi.org/10.1038/sj.onc.1207853
    • (2004) Oncogene , vol.23 , pp. 6218-6225
    • Kim, H.1    Nam, S.W.2    Rhee, H.3    Shan Li, L.4    Ju Kang, H.5    Hye Koh, K.6    Kyu Kim, N.7    Song, J.8    Tak-Bun Liu, E.9    Kim, H.10
  • 7
    • 1842867040 scopus 로고    scopus 로고
    • Tumour-infiltrating lymphocytes in colorectal cancer with microsatellite instability are activated and cytotoxic
    • PMID:15048750
    • Phillips SM, Banerjea A, Feakins R, Li SR, Bustin SA, Dorudi S. Tumour-infiltrating lymphocytes in colorectal cancer with microsatellite instability are activated and cytotoxic. British J Surg 2004; 91:469-75; PMID:15048750; http://dx.doi.org/10.1002/bjs.4472
    • (2004) British J Surg , vol.91 , pp. 469-475
    • Phillips, S.M.1    Banerjea, A.2    Feakins, R.3    Li, S.R.4    Bustin, S.A.5    Dorudi, S.6
  • 8
    • 19944365184 scopus 로고    scopus 로고
    • Microsatellite instability in colorectal cancer is associated with local lymphocyte infiltration and low frequency of distant metastases
    • PMID:15856045
    • Buckowitz A, Knaebel HP, Benner A, Bläker H, Gebert J, Kienle P, von Knebel Doeberitz M, Kloor M. Microsatellite instability in colorectal cancer is associated with local lymphocyte infiltration and low frequency of distant metastases. British J Cancer 2005; 92:1746-53; PMID:15856045; http://dx.doi.org/10.1038/sj.bjc.6602534
    • (2005) British J Cancer , vol.92 , pp. 1746-1753
    • Buckowitz, A.1    Knaebel, H.P.2    Benner, A.3    Bläker, H.4    Gebert, J.5    Kienle, P.6    Von Knebel Doeberitz, M.7    Kloor, M.8
  • 9
    • 27444445519 scopus 로고    scopus 로고
    • The immunogenicity of colorectal cancers with high-degree microsatellite instability
    • PMID:15890075
    • Banerjea A, Bustin SA, Dorudi S. The immunogenicity of colorectal cancers with high-degree microsatellite instability. World J Surg Oncol 2005; 3:26; PMID:15890075; http://dx.doi.org/10.1186/1477-7819-3-26
    • (2005) World J Surg Oncol , vol.3 , pp. 26
    • Banerjea, A.1    Bustin, S.A.2    Dorudi, S.3
  • 10
    • 33845608798 scopus 로고    scopus 로고
    • Classification of colorectal cancer based on correlation of clinical, morphological and molecular features
    • PMID:17204026
    • Jass JR. Classification of colorectal cancer based on correlation of clinical, morphological and molecular features. Histopathology 2007; 50:113-30; PMID:17204026; http://dx.doi.org/10.1111/j.1365-2559.2006.02549.x
    • (2007) Histopathology , vol.50 , pp. 113-130
    • Jass, J.R.1
  • 11
    • 84893183937 scopus 로고    scopus 로고
    • J€ons T, Andrade-Navarro MA, Kemmner W. Concerted down-regulation of immunesystem related genes predicts metastasis in colorectal carcinoma
    • PMID:24495478
    • Fehlker M, Huska MR, J€ons T, Andrade-Navarro MA, Kemmner W. Concerted down-regulation of immunesystem related genes predicts metastasis in colorectal carcinoma. BMC Cancer 2014; 14:64; PMID:24495478; http://dx.doi.org/10.1186/1471-2407-14-64
    • (2014) BMC Cancer , vol.14 , pp. 64
    • Fehlker, M.1    Huska, M.R.2
  • 16
    • 84873096362 scopus 로고    scopus 로고
    • Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas
    • PMID:23263490
    • Palles C, Cazier JB, Howarth KM, Domingo E, Jones AM, Broderick P, Kemp Z, Spain SL, Guarino E, Salguero I et al. Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas. Nat Genet 2013; 45:136-44; PMID:23263490; http://dx.doi.org/10.1038/ng.2503
    • (2013) Nat Genet , vol.45 , pp. 136-144
    • Palles, C.1    Cazier, J.B.2    Howarth, K.M.3    Domingo, E.4    Jones, A.M.5    Broderick, P.6    Kemp, Z.7    Spain, S.L.8    Guarino, E.9    Salguero, I.10
  • 17
  • 19
    • 0030848161 scopus 로고    scopus 로고
    • Induction of a CD8C cytotoxic T lymphocyte response by cross-priming requires cognate CD4C T cell help
    • PMID:9206998
    • Bennett SR, Carbone FR, Karamalis F, Miller JF, Heath WR. Induction of a CD8C cytotoxic T lymphocyte response by cross-priming requires cognate CD4C T cell help. J Exp Med 1997; 186:65-70; PMID:9206998; http://dx.doi.org/10.1084/jem.186.1.65
    • (1997) J Exp Med , vol.186 , pp. 65-70
    • Bennett, S.R.1    Carbone, F.R.2    Karamalis, F.3    Miller, J.F.4    Heath, W.R.5
  • 20
    • 0032482356 scopus 로고    scopus 로고
    • Help for cytotoxic-T-cell responses is mediated by CD40 signalling
    • PMID:9624004
    • Bennett SR, Carbone FR, Karamalis F, Flavell RA, Miller JF, Heath WR. Help for cytotoxic-T-cell responses is mediated by CD40 signalling. Nature 1998; 393:478-80; PMID:9624004; http://dx.doi.org/10.1038/30996
    • (1998) Nature , vol.393 , pp. 478-480
    • Bennett, S.R.1    Carbone, F.R.2    Karamalis, F.3    Flavell, R.A.4    Miller, J.F.5    Heath, W.R.6
  • 21
    • 0037456367 scopus 로고    scopus 로고
    • CD4C T cells are required for secondary expansion and memory in CD8C T lymphocytes
    • PMID:12594515
    • Janssen EM, Lemmens EE, Wolfe T, Christen U, von Herrath MG, Schoenberger SP. CD4C T cells are required for secondary expansion and memory in CD8C T lymphocytes. Nature 2003; 421:852-6; PMID:12594515; http://dx.doi.org/10.1038/nature01441
    • (2003) Nature , vol.421 , pp. 852-856
    • Janssen, E.M.1    Lemmens, E.E.2    Wolfe, T.3    Christen, U.4    Von Herrath, M.G.5    Schoenberger, S.P.6
  • 22
    • 33745224089 scopus 로고    scopus 로고
    • Interleukin-2 signals during priming are required for secondary expansion of CD8C memory T cells
    • PMID:16778891
    • Williams MA, Tyznik AJ, Bevan MJ. Interleukin-2 signals during priming are required for secondary expansion of CD8C memory T cells. Nature 2006; 441:890-3; PMID:16778891; http://dx.doi.org/10.1038/nature04790
    • (2006) Nature , vol.441 , pp. 890-893
    • Williams, M.A.1    Tyznik, A.J.2    Bevan, M.J.3
  • 23
    • 77949530108 scopus 로고    scopus 로고
    • Naive tumor-specific CD4(C) T cells differentiated in vivo eradicate established melanoma
    • PMID:20156973
    • Xie Y, Akpinarli A, Maris C, Hipkiss EL, Lane M, Kwon EK, Muranski P, Restifo NP, Antony PA. Naive tumor-specific CD4(C) T cells differentiated in vivo eradicate established melanoma. J Exp Med 2010; 207:651-67; PMID:20156973; http://dx.doi.org/10.1084/jem.20091921
    • (2010) J Exp Med , vol.207 , pp. 651-667
    • Xie, Y.1    Akpinarli, A.2    Maris, C.3    Hipkiss, E.L.4    Lane, M.5    Kwon, E.K.6    Muranski, P.7    Restifo, N.P.8    Antony, P.A.9
  • 24
    • 77949522803 scopus 로고    scopus 로고
    • Tumor-reactive CD4(C) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
    • PMID:20156971
    • Quezada SA, Simpson TR, Peggs KS, Merghoub T, Vider J, Fan X, Blasberg R, Yagita H, Muranski P, Antony PA et al. Tumor-reactive CD4(C) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts. J Exp Med 2010; 207:637-50; PMID:20156971; http://dx.doi.org/10.1084/jem.20091918
    • (2010) J Exp Med , vol.207 , pp. 637-650
    • Quezada, S.A.1    Simpson, T.R.2    Peggs, K.S.3    Merghoub, T.4    Vider, J.5    Fan, X.6    Blasberg, R.7    Yagita, H.8    Muranski, P.9    Antony, P.A.10
  • 28
    • 18544380239 scopus 로고    scopus 로고
    • Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
    • PMID:12091876
    • Dong H, Strome SE, Salomao DR, Tamura H, Hirano F, Flies DB, Roche PC, Lu J, Zhu G, Tamada K et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med 2002; 8:793-800; PMID:12091876; http://dx.doi.org/10.1038/nm0902-1039c
    • (2002) Nat Med , vol.8 , pp. 793-800
    • Dong, H.1    Strome, S.E.2    Salomao, D.R.3    Tamura, H.4    Hirano, F.5    Flies, D.B.6    Roche, P.C.7    Lu, J.8    Zhu, G.9    Tamada, K.10
  • 29
    • 31444451661 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274)
    • PMID:16413538
    • Lee SJ, Jang BC, Lee SW, Yang YI, Suh SI, Park YM, Oh S, Shin JG, Yao S, Chen L et al. Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274). FEBS Lett 2006; 580:755-62; PMID:16413538; http://dx.doi.org/10.1016/j.febslet.2005.12.093
    • (2006) FEBS Lett , vol.580 , pp. 755-762
    • Lee, S.J.1    Jang, B.C.2    Lee, S.W.3    Yang, Y.I.4    Suh, S.I.5    Park, Y.M.6    Oh, S.7    Shin, J.G.8    Yao, S.9    Chen, L.10
  • 30
    • 84863115998 scopus 로고    scopus 로고
    • Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape
    • PMID:22186141
    • Woo SR, Turnis ME, Goldberg MV, Bankoti J, Selby M, Nirschl CJ, Bettini ML, Gravano DM, Vogel P, Liu CL et al. Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape. Cancer Res 2011; 72:917-27; PMID:22186141; http://dx.doi.org/10.1158/0008-5472.CAN-11-1620
    • (2011) Cancer Res , vol.72 , pp. 917-927
    • Woo, S.R.1    Turnis, M.E.2    Goldberg, M.V.3    Bankoti, J.4    Selby, M.5    Nirschl, C.J.6    Bettini, M.L.7    Gravano, D.M.8    Vogel, P.9    Liu, C.L.10
  • 31
    • 0242708508 scopus 로고    scopus 로고
    • Strong HLA-DR expression in microsatellite stable carcinomas of the large bowel is associated with good prognosis
    • PMID:12232760
    • Løvig T, Andersen SN, Thorstensen L, Diep CB, Meling GI, Lothe RA, Rognum TO. Strong HLA-DR expression in microsatellite stable carcinomas of the large bowel is associated with good prognosis. British J Cancer 2002; 87:756-62; PMID:12232760; http://dx.doi.org/10.1038/sj.bjc.6600507
    • (2002) British J Cancer , vol.87 , pp. 756-762
    • Løvig, T.1    Ersen, S.N.2    Thorstensen, L.3    Diep, C.B.4    Meling, G.I.5    Lothe, R.A.6    Rognum, T.O.7
  • 33
    • 78349277576 scopus 로고    scopus 로고
    • Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: Cohort study and literature review
    • PMID:20927778
    • Nosho K, Baba Y, Tanaka N, Shima K, Hayashi M, Meyerhardt JA, Giovannucci E, Dranoff G, Fuchs CS, Ogino S. Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature review. J Pathol 2010; 222:350-66; PMID:20927778; http://dx.doi.org/10.1002/path.2774
    • (2010) J Pathol , vol.222 , pp. 350-366
    • Nosho, K.1    Baba, Y.2    Tanaka, N.3    Shima, K.4    Hayashi, M.5    Meyerhardt, J.A.6    Giovannucci, E.7    Dranoff, G.8    Fuchs, C.S.9    Ogino, S.10
  • 34
    • 0023845231 scopus 로고
    • Kirsten murine sarcoma virus abolishes interferon gamma-induced class II but not class I major histocompatibility antigen expression in a murine fibroblast line
    • PMID:2831293
    • Maudsley DJ, Morris AG. Kirsten murine sarcoma virus abolishes interferon gamma-induced class II but not class I major histocompatibility antigen expression in a murine fibroblast line. J Exp Med 1988; 167:706-11; PMID:2831293; http://dx.doi.org/10.1084/jem.167.2.706
    • (1988) J Exp Med , vol.167 , pp. 706-711
    • Maudsley, D.J.1    Morris, A.G.2
  • 35
    • 0025752591 scopus 로고
    • Reduced stimulation of helper T cells by Ki-ras transformed cells
    • PMID:1826672
    • Maudsley DJ, Bateman WJ, Morris AG. Reduced stimulation of helper T cells by Ki-ras transformed cells. Immunology 1991; 72:277-81; PMID:1826672
    • (1991) Immunology , vol.72 , pp. 277-281
    • Maudsley, D.J.1    Bateman, W.J.2    Morris, A.G.3
  • 36
    • 1242319374 scopus 로고    scopus 로고
    • St€orkel S, Seliger B. MHC class I antigen processing pathway defects, ras mutations and disease stage in colorectal carcinoma
    • Atkins D, Breuckmann A, Schmahl GE, Binner P, Ferrone S, Krummenauer F, St€orkel S, Seliger B. MHC class I antigen processing pathway defects, ras mutations and disease stage in colorectal carcinoma. Int J Cancer 2004; 109:265-73; http://dx.doi.org/10.1002/ijc.11681
    • (2004) Int J Cancer , vol.109 , pp. 265-273
    • Atkins, D.1    Breuckmann, A.2    Schmahl, G.E.3    Binner, P.4    Ferrone, S.5    Krummenauer, F.6
  • 37
    • 44749084859 scopus 로고    scopus 로고
    • Role of Stat3 in suppressing anti-tumor immunity
    • PMID:18479894
    • Kortylewski M, Yu H. Role of Stat3 in suppressing anti-tumor immunity. Curr Opin Immunol 2008; 20:228-33; PMID:18479894; http://dx.doi.org/10.1016/j.coi.2008.03.010
    • (2008) Curr Opin Immunol , vol.20 , pp. 228-233
    • Kortylewski, M.1    Yu, H.2
  • 38
    • 51349123892 scopus 로고    scopus 로고
    • Cancer immunotherapy by dendritic cells
    • PMID:18799145
    • Melief CJ. Cancer immunotherapy by dendritic cells. Immunity 2008; 29:372-83; PMID:18799145; http://dx.doi.org/10.1016/j.immuni.2008.08.004
    • (2008) Immunity , vol.29 , pp. 372-383
    • Melief, C.J.1
  • 39
    • 84863561591 scopus 로고    scopus 로고
    • Oncogenic PI3K mutations lead to NF-kappaB-dependent cytokine expression following growth factor deprivation
    • PMID:22552288
    • Hutti JE, Pfefferle AD, Russell SC, Sircar M, Perou CM, Baldwin AS. Oncogenic PI3K mutations lead to NF-kappaB-dependent cytokine expression following growth factor deprivation. Cancer Res 2012; 72:3260-9; PMID:22552288; http://dx.doi.org/10.1158/0008-5472.CAN-11-4141
    • (2012) Cancer Res , vol.72 , pp. 3260-3269
    • Hutti, J.E.1    Pfefferle, A.D.2    Russell, S.C.3    Sircar, M.4    Perou, C.M.5    Baldwin, A.S.6
  • 40
    • 0025998557 scopus 로고
    • Aspirin use and reduced risk of fatal colon cancer
    • PMID:1669840
    • Thun MJ, Namboodiri MM, Heath CW. Aspirin use and reduced risk of fatal colon cancer. N Engl J Med 1991; 325:1593-6; PMID:1669840; http://dx.doi.org/10.1056/NEJM199112053252301
    • (1991) N Engl J Med , vol.325 , pp. 1593-1596
    • Thun, M.J.1    Namboodiri, M.M.2    Heath, C.W.3
  • 46
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • PMID:22810696
    • Comprehensive molecular characterization of human colon and rectal cancer. Nature 2012; 487:330-7; PMID:22810696; http://dx.doi.org/10.1038/nature11252
    • (2012) Nature , vol.487 , pp. 330-337


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