-
1
-
-
58149165364
-
Results of the Cord Blood Transplantation Study (COBLT) : Clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies
-
Kurtzberg J, Prasad VK, Carter SL, et al. Results of the Cord Blood Transplantation Study (COBLT) : Clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies. Blood 2008; 112: 4318-4327.
-
(2008)
Blood
, vol.112
, pp. 4318-4327
-
-
Kurtzberg, J.1
Prasad, V.K.2
Carter, S.L.3
-
2
-
-
78649462137
-
Allogeneic hematopoietic cell transplantation for hematologic malignancy: Relative risks and benefits of double umbilical cord blood
-
Brunstein CG, Gutman JA, Weisdorf DJ, et al. Allogeneic hematopoietic cell transplantation for hematologic malignancy: Relative risks and benefits of double umbilical cord blood. Blood 2010; 116: 4693-4699.
-
(2010)
Blood
, vol.116
, pp. 4693-4699
-
-
Brunstein, C.G.1
Gutman, J.A.2
Weisdorf, D.J.3
-
3
-
-
79960172161
-
Delayed platelet recovery after allogeneic transplantation: A predictor of increased treatment-related mortality and poorer survival
-
Ramirez P, Brunstein CG, Miller B, et al. Delayed platelet recovery after allogeneic transplantation: A predictor of increased treatment-related mortality and poorer survival. Bone Marrow Transplant 2011; 46: 981-986.
-
(2011)
Bone Marrow Transplant
, vol.46
, pp. 981-986
-
-
Ramirez, P.1
Brunstein, C.G.2
Miller, B.3
-
4
-
-
9244219607
-
Transplants of umbilical-cord blood or bone marrow from unrelated donors in adults with acute leukemia
-
Rocha V, Labopin M, Sanz G, et al. Transplants of umbilical-cord blood or bone marrow from unrelated donors in adults with acute leukemia. N Engl J Med 2004; 351: 2276-2285.
-
(2004)
N Engl J Med
, vol.351
, pp. 2276-2285
-
-
Rocha, V.1
Labopin, M.2
Sanz, G.3
-
5
-
-
84888212251
-
Analysis of the clonal growth and differentiation dynamics of primitive barcoded human cord blood cells in NSG mice
-
Cheung AM, Nguyen LV, Carles A, et al. Analysis of the clonal growth and differentiation dynamics of primitive barcoded human cord blood cells in NSG mice. Blood 2013; 122: 3129-3137.
-
(2013)
Blood
, vol.122
, pp. 3129-3137
-
-
Cheung, A.M.1
Nguyen, L.V.2
Carles, A.3
-
7
-
-
79960106880
-
Isolation of single human hematopoietic stem cells capable of long-Term multilineage engraftment
-
Notta F, Doulatov S, Laurenti E, et al. Isolation of single human hematopoietic stem cells capable of long-Term multilineage engraftment. Science 2011; 333: 218-221.
-
(2011)
Science
, vol.333
, pp. 218-221
-
-
Notta, F.1
Doulatov, S.2
Laurenti, E.3
-
8
-
-
3242754448
-
Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity
-
Hope KJ, Jin L, Dick JE. Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity. Nat Immunol 2004; 5: 738-743.
-
(2004)
Nat Immunol
, vol.5
, pp. 738-743
-
-
Hope, K.J.1
Jin, L.2
Dick, J.E.3
-
10
-
-
84863011896
-
Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling
-
Csaszar E, Kirouac DC, Yu M, et al. Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling. Cell Stem Cell 2012; 10: 218-229.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 218-229
-
-
Csaszar, E.1
Kirouac, D.C.2
Yu, M.3
-
11
-
-
84871071832
-
Cord-blood engraftment with ex vivo mesenchymal-cell coculture
-
de Lima M, McNiece I, Robinson SN, et al. Cord-blood engraftment with ex vivo mesenchymal-cell coculture. N Engl J Med 2012; 367: 2305-2315.
-
(2012)
N Engl J Med
, vol.367
, pp. 2305-2315
-
-
De Lima, M.1
McNiece, I.2
Robinson, S.N.3
-
12
-
-
84923351242
-
Niche-based screening in multiple myeloma identifies a kinesin-5 inhibitor with improved selectivity over hematopoietic progenitors
-
Chattopadhyay S, Stewart AL, Mukherjee S, et al. Niche-based screening in multiple myeloma identifies a kinesin-5 inhibitor with improved selectivity over hematopoietic progenitors. Cell Rep 2015; 10: 755-770.
-
(2015)
Cell Rep
, vol.10
, pp. 755-770
-
-
Chattopadhyay, S.1
Stewart, A.L.2
Mukherjee, S.3
-
13
-
-
84920063456
-
Long term maintenance of myeloid leukemic stem cells cultured with unrelated human mesenchymal stromal cells
-
Ito S, Barrett AJ, Dutra A, et al. Long term maintenance of myeloid leukemic stem cells cultured with unrelated human mesenchymal stromal cells. Stem Cell Res 2015; 14: 95-104.
-
(2015)
Stem Cell Res
, vol.14
, pp. 95-104
-
-
Ito, S.1
Barrett, A.J.2
Dutra, A.3
-
14
-
-
76349113345
-
Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution
-
Delaney C, Heimfeld S, Brashem-Stein C, et al. Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution. Nat Med 2010; 16: 232-236.
-
(2010)
Nat Med
, vol.16
, pp. 232-236
-
-
Delaney, C.1
Heimfeld, S.2
Brashem-Stein, C.3
-
15
-
-
77956519710
-
Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells
-
Boitano AE, Wang J, Romeo R, et al. Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science 2010; 329: 1345-1348.
-
(2010)
Science
, vol.329
, pp. 1345-1348
-
-
Boitano, A.E.1
Wang, J.2
Romeo, R.3
-
16
-
-
34250883337
-
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis
-
North TE, Goessling W, Walkley CR, et al. Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature 2007; 447: 1007-1011.
-
(2007)
Nature
, vol.447
, pp. 1007-1011
-
-
North, T.E.1
Goessling, W.2
Walkley, C.R.3
-
17
-
-
67049134758
-
Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation
-
Hoggatt J, Singh P, Sampath J, Pelus LM. Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation. Blood 2009; 113: 5444-5455.
-
(2009)
Blood
, vol.113
, pp. 5444-5455
-
-
Hoggatt, J.1
Singh, P.2
Sampath, J.3
Pelus, L.M.4
-
18
-
-
79953885122
-
Prostaglandin E2 enhances human cord blood stemcell xenotransplants and shows long-Term safety in preclinical nonhuman primate transplant models
-
Goessling W, Allen RS, Guan X, et al. Prostaglandin E2 enhances human cord blood stemcell xenotransplants and shows long-Term safety in preclinical nonhuman primate transplant models. Cell Stem Cell 2011; 8: 445-458.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 445-458
-
-
Goessling, W.1
Allen, R.S.2
Guan, X.3
-
19
-
-
34347334543
-
+ or lineage-human umbilical cord blood donor hematopoietic stem cells/hematopoietic progenitor cells improves long-Term engraftment into NOD/SCID/Beta2null immunodeficient mice
-
+ or lineage-human umbilical cord blood donor hematopoietic stem cells/hematopoietic progenitor cells improves long-Term engraftment into NOD/SCID/Beta2null immunodeficient mice. Stem Cells Dev 2007; 16: 355-360.
-
(2007)
Stem Cells Dev
, vol.16
, pp. 355-360
-
-
Christopherson, K.W.1
Paganessi, L.A.2
Napier, S.3
Porecha, N.K.4
-
20
-
-
2942622157
-
+ cells and increases their engraftment potential in NOD/SCID mice
-
+ cells and increases their engraftment potential in NOD/SCID mice. Exp Hematol 2004; 32: 547-555.
-
(2004)
Exp Hematol
, vol.32
, pp. 547-555
-
-
Peled, T.1
Landau, E.2
Mandel, J.3
-
21
-
-
84858339102
-
Nicotinamide, a SIRT1 inhibitor, inhibits differentiation and facilitates expansion of hematopoietic progenitor cells with enhanced bone marrow homing and engraftment
-
Peled T, Shoham H, Aschengrau D, et al. Nicotinamide, a SIRT1 inhibitor, inhibits differentiation and facilitates expansion of hematopoietic progenitor cells with enhanced bone marrow homing and engraftment. Exp Hematol 2012; 40: 342.e1-355.e1.
-
(2012)
Exp Hematol
, vol.40
, pp. 342e1-355e1
-
-
Peled, T.1
Shoham, H.2
Aschengrau, D.3
-
22
-
-
84902206817
-
Epigenetic reprogramming induces the expansion of cord blood stem cells
-
Chaurasia P, Gajzer DC, Schaniel C, et al. Epigenetic reprogramming induces the expansion of cord blood stem cells. J Clin Invest 2014; 124: 2378-2395.
-
(2014)
J Clin Invest
, vol.124
, pp. 2378-2395
-
-
Chaurasia, P.1
Gajzer, D.C.2
Schaniel, C.3
-
23
-
-
84907221142
-
Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal
-
Fares I, Chagraoui J, Gareau Y, et al. Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal. Science 2014; 345: 1509-1512.
-
(2014)
Science
, vol.345
, pp. 1509-1512
-
-
Fares, I.1
Chagraoui, J.2
Gareau, Y.3
-
24
-
-
77949354161
-
In vivo prostaglandin E2 treatment alters the bone marrow microenvironment and preferentially expands shortterm hematopoietic stem cells
-
Frisch BJ, Porter RL, Gigliotti BJ, et al. In vivo prostaglandin E2 treatment alters the bone marrow microenvironment and preferentially expands shortterm hematopoietic stem cells. Blood 2009; 114: 4054-4063.
-
(2009)
Blood
, vol.114
, pp. 4054-4063
-
-
Frisch, B.J.1
Porter, R.L.2
Gigliotti, B.J.3
-
25
-
-
62149148156
-
Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration
-
Goessling W, North TE, Loewer S, et al. Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell 2009; 136: 1136-1147.
-
(2009)
Cell
, vol.136
, pp. 1136-1147
-
-
Goessling, W.1
North, T.E.2
Loewer, S.3
-
26
-
-
84888273208
-
Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation
-
Cutler C, Multani P, Robbins D, et al. Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. Blood 2013; 122: 3074-3081.
-
(2013)
Blood
, vol.122
, pp. 3074-3081
-
-
Cutler, C.1
Multani, P.2
Robbins, D.3
-
27
-
-
84875956072
-
In vivo DPP-4 inhibition to enhance engraftment of single-unit cord blood transplants in adults with hematological malignancies
-
Farag SS, Srivastava S, Messina-Graham S, et al. In vivo DPP-4 inhibition to enhance engraftment of single-unit cord blood transplants in adults with hematological malignancies. Stem Cells Dev 2013; 22: 1007-1015.
-
(2013)
Stem Cells Dev
, vol.22
, pp. 1007-1015
-
-
Farag, S.S.1
Srivastava, S.2
Messina-Graham, S.3
-
28
-
-
43849087808
-
Transplantation of ex vivo expanded cord blood cells using the copper chelator tetraethylenepentamine: A phase I/II clinical trial
-
de Lima M, McMannis J, Gee A, et al. Transplantation of ex vivo expanded cord blood cells using the copper chelator tetraethylenepentamine: A phase I/II clinical trial. Bone Marrow Transplant 2008; 41: 771-778.
-
(2008)
Bone Marrow Transplant
, vol.41
, pp. 771-778
-
-
De Lima, M.1
McMannis, J.2
Gee, A.3
-
29
-
-
84903794165
-
Umbilical cord blood expansion with nicotinamide provides long-Term multilineage engraftment
-
Horwitz ME, Chao NJ, Rizzieri DA, et al. Umbilical cord blood expansion with nicotinamide provides long-Term multilineage engraftment. J Clin Invest 2014; 124: 3121-3128.
-
(2014)
J Clin Invest
, vol.124
, pp. 3121-3128
-
-
Horwitz, M.E.1
Chao, N.J.2
Rizzieri, D.A.3
-
30
-
-
47149088471
-
Cytokines regulating hematopoietic stem cell function
-
Zhang CC, Lodish HF. Cytokines regulating hematopoietic stem cell function. Curr Opin Hematol 2008; 15: 307-311.
-
(2008)
Curr Opin Hematol
, vol.15
, pp. 307-311
-
-
Zhang, C.C.1
Lodish, H.F.2
-
31
-
-
84874299202
-
Rapid and sustained engraftment of a single allogeneic ex-vivo expanded cord blood unit (CBU) after reduced intensity conditioning (RIC) in adults. Preliminary Results of a Prospective Trial
-
Abstract 486
-
Milpied N, Dazey B, Ivanovic Z, et al. Rapid and sustained engraftment of a single allogeneic ex-vivo expanded cord blood unit (CBU) after reduced intensity conditioning (RIC) in adults. Preliminary Results of a Prospective Trial. Blood (ASH Annual Meeting Abstracts) 2011, 118 (Abstract 486).
-
(2011)
Blood (ASH Annual Meeting Abstracts)
, pp. 118
-
-
Milpied, N.1
Dazey, B.2
Ivanovic, Z.3
-
32
-
-
80855164547
-
Clinical-scale cultures of cord blood CD34 (+) cells to amplify committed progenitors and maintain stem cell activity
-
Ivanovic Z, Duchez P, Chevaleyre J, et al. Clinical-scale cultures of cord blood CD34 (+) cells to amplify committed progenitors and maintain stem cell activity. Cell Transplant 2011; 20: 1453-1463.
-
(2011)
Cell Transplant
, vol.20
, pp. 1453-1463
-
-
Ivanovic, Z.1
Duchez, P.2
Chevaleyre, J.3
-
33
-
-
79953681887
-
Small-molecule regulators of human stem cell self-renewal
-
Bouchez LC, Boitano AE, de Lichtervelde L, et al. Small-molecule regulators of human stem cell self-renewal. Chembiochem 2011; 12: 854-857.
-
(2011)
Chembiochem
, vol.12
, pp. 854-857
-
-
Bouchez, L.C.1
Boitano, A.E.2
De Lichtervelde, L.3
-
34
-
-
84869162797
-
G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment
-
Chen X, Skutt-Kakaria K, Davison J, et al. G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment. Genes Dev 2012; 26: 2499-2511.
-
(2012)
Genes Dev
, vol.26
, pp. 2499-2511
-
-
Chen, X.1
Skutt-Kakaria, K.2
Davison, J.3
-
35
-
-
84904304099
-
Small molecule inhibitors in acute myeloid leukemia: From the bench to the clinic
-
Al-Hussaini M, DiPersio JF. Small molecule inhibitors in acute myeloid leukemia: From the bench to the clinic. Expert Rev Hematol 2014; 7: 439-464.
-
(2014)
Expert Rev Hematol
, vol.7
, pp. 439-464
-
-
Al-Hussaini, M.1
DiPersio, J.F.2
-
36
-
-
33746498580
-
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9
-
Krivtsov AV, Twomey D, Feng Z, et al. Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature 2006; 442: 818-822.
-
(2006)
Nature
, vol.442
, pp. 818-822
-
-
Krivtsov, A.V.1
Twomey, D.2
Feng, Z.3
-
37
-
-
78751661556
-
Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells
-
Notta F, Mullighan CG, Wang JC, et al. Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells. Nature 2011; 469: 362-367.
-
(2011)
Nature
, vol.469
, pp. 362-367
-
-
Notta, F.1
Mullighan, C.G.2
Wang, J.C.3
-
38
-
-
78751644099
-
Genetic variegation of clonal architecture and propagating cells in leukaemia
-
Anderson K, Lutz C, van Delft FW, et al. Genetic variegation of clonal architecture and propagating cells in leukaemia. Nature 2011; 469: 356-361.
-
(2011)
Nature
, vol.469
, pp. 356-361
-
-
Anderson, K.1
Lutz, C.2
Van Delft, F.W.3
-
39
-
-
84897954369
-
Identification of small molecules that support human leukemia stem cell activity ex vivo
-
Pabst C, Krosl J, Fares I, et al. Identification of small molecules that support human leukemia stem cell activity ex vivo. Nat Methods 2014; 11: 436-442.
-
(2014)
Nat Methods
, vol.11
, pp. 436-442
-
-
Pabst, C.1
Krosl, J.2
Fares, I.3
-
40
-
-
34250789303
-
Therapeutic implications of leukemia stem cell development
-
Stubbs MC, Armstrong SA. Therapeutic implications of leukemia stem cell development. Clin Cancer Res 2007; 13: 3439-3442.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3439-3442
-
-
Stubbs, M.C.1
Armstrong, S.A.2
-
41
-
-
84927583177
-
Stemistry: The control of stem cells in situ using chemistry
-
Davies SG, Kennewell PD, Russell AJ, et al. Stemistry: The control of stem cells in situ using chemistry. J Med Chem 2015; 28: 2863-2894.
-
(2015)
J Med Chem
, vol.28
, pp. 2863-2894
-
-
Davies, S.G.1
Kennewell, P.D.2
Russell, A.J.3
|