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Volumn 144, Issue 2, 2015, Pages 278-288

Prognostic significance of tumor-infiltrating lymphocytes and the tertiary lymphoid structures in HER2-positive breast cancer treated with adjuvant trastuzumab

Author keywords

Breast carcinoma; HER2; Lymphocytes; MHC I; Tertiary lymphoid structure; Trastuzumab

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; HLA A ANTIGEN; HLA ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TRASTUZUMAB; ANTINEOPLASTIC AGENT; ERBB2 PROTEIN, HUMAN; HLA ANTIGEN CLASS 1; MONOCLONAL ANTIBODY;

EID: 84942581895     PISSN: 00029173     EISSN: 19437722     Source Type: Journal    
DOI: 10.1309/AJCPIXUYDVZ0RZ3G     Document Type: Article
Times cited : (112)

References (38)
  • 1
    • 84901591504 scopus 로고    scopus 로고
    • Two histopathologically different diseases: Hormone receptor-positive and hormone receptor-negative tumors in HER2-positive breast cancer
    • Lee HJ, Park IA, Park SY, et al. Two histopathologically different diseases: hormone receptor-positive and hormone receptor-negative tumors in HER2-positive breast cancer. Breast Cancer Res Treat. 2014;145:615-623.
    • (2014) Breast Cancer Res Treat. , vol.145 , pp. 615-623
    • Lee, H.J.1    Park, I.A.2    Park, S.Y.3
  • 2
    • 73949092850 scopus 로고    scopus 로고
    • Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer
    • Denkert C, Loibl S, Noske A, et al. Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer. J Clin Oncol. 2010;28:105-113.
    • (2010) J Clin Oncol. , vol.28 , pp. 105-113
    • Denkert, C.1    Loibl, S.2    Noske, A.3
  • 3
    • 84866784769 scopus 로고    scopus 로고
    • Impact of hormone receptor status on patterns of recurrence and clinical outcomes among patients with human epidermal growth factor-2-positive breast cancer in the National Comprehensive Cancer Network: A prospective cohort study
    • Vaz-Luis I, Ottesen RA, Hughes ME, et al. Impact of hormone receptor status on patterns of recurrence and clinical outcomes among patients with human epidermal growth factor-2-positive breast cancer in the National Comprehensive Cancer Network: a prospective cohort study. Breast Cancer Res. 2012;14:R129.
    • (2012) Breast Cancer Res. , vol.14 , pp. R129
    • Vaz-Luis, I.1    Ottesen, R.A.2    Hughes, M.E.3
  • 4
    • 79959374405 scopus 로고    scopus 로고
    • Vascular characterisation of triple negative breast carcinomas using dynamic MRI
    • Li SP, Padhani AR, Taylor NJ, et al. Vascular characterisation of triple negative breast carcinomas using dynamic MRI. Eur Radiol. 2011;21:1364-1373.
    • (2011) Eur Radiol. , vol.21 , pp. 1364-1373
    • Li, S.P.1    Padhani, A.R.2    Taylor, N.J.3
  • 5
    • 84875722651 scopus 로고    scopus 로고
    • Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98
    • Loi S, Sirtaine N, Piette F, et al. Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98. J Clin Oncol. 2013;31:860-867.
    • (2013) J Clin Oncol. , vol.31 , pp. 860-867
    • Loi, S.1    Sirtaine, N.2    Piette, F.3
  • 6
    • 84876086929 scopus 로고    scopus 로고
    • Tumor-associated lymphocytes predict response to neoadjuvant chemotherapy in breast cancer patients
    • Lee HJ, Seo JY, Ahn JH, et al. Tumor-associated lymphocytes predict response to neoadjuvant chemotherapy in breast cancer patients. J Breast Cancer. 2013;16:32-39.
    • (2013) J Breast Cancer. , vol.16 , pp. 32-39
    • Lee, H.J.1    Seo, J.Y.2    Ahn, J.H.3
  • 7
    • 84887851057 scopus 로고    scopus 로고
    • Tumour-infiltrating CD8+ lymphocytes as an independent predictive factor for pathological complete response to primary systemic therapy in breast cancer
    • Seo AN, Lee HJ, Kim EJ, et al. Tumour-infiltrating CD8+ lymphocytes as an independent predictive factor for pathological complete response to primary systemic therapy in breast cancer. Br J Cancer. 2013;109:2705-2713.
    • (2013) Br J Cancer. , vol.109 , pp. 2705-2713
    • Seo, A.N.1    Lee, H.J.2    Kim, E.J.3
  • 8
    • 84884589344 scopus 로고    scopus 로고
    • The relationship between lymphocyte subsets and clinico-pathological determinants of survival in patients with primary operable invasive ductal breast cancer
    • Mohammed ZM, Going JJ, Edwards J, et al. The relationship between lymphocyte subsets and clinico-pathological determinants of survival in patients with primary operable invasive ductal breast cancer. Br J Cancer. 2013;109:1676-1684.
    • (2013) Br J Cancer. , vol.109 , pp. 1676-1684
    • Mohammed, Z.M.1    Going, J.J.2    Edwards, J.3
  • 9
    • 84865418286 scopus 로고    scopus 로고
    • The relationship between components of tumour inflammatory cell infiltrate and clinicopathological factors and survival in patients with primary operable invasive ductal breast cancer
    • Mohammed ZM, Going JJ, Edwards J, et al. The relationship between components of tumour inflammatory cell infiltrate and clinicopathological factors and survival in patients with primary operable invasive ductal breast cancer. Br J Cancer. 2012;107:864-873.
    • (2012) Br J Cancer. , vol.107 , pp. 864-873
    • Mohammed, Z.M.1    Going, J.J.2    Edwards, J.3
  • 10
    • 84876795089 scopus 로고    scopus 로고
    • Increased lymphocytic infiltration in breast cancer correlated with molecular subtypes and HER2 gene amplification
    • Tsang JY, Ni YB, Chan SK, et al. Increased lymphocytic infiltration in breast cancer correlated with molecular subtypes and HER2 gene amplification. Histopathology. 2013;62:963-965.
    • (2013) Histopathology. , vol.62 , pp. 963-965
    • Tsang, J.Y.1    Ni, Y.B.2    Chan, S.K.3
  • 11
    • 26844503270 scopus 로고    scopus 로고
    • Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
    • Piccart-Gebhart MJ, Procter M, Leyland-Jones B, et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med. 2005;353:1659-1672.
    • (2005) N Engl J Med. , vol.353 , pp. 1659-1672
    • Piccart-Gebhart, M.J.1    Procter, M.2    Leyland-Jones, B.3
  • 12
    • 84865793850 scopus 로고    scopus 로고
    • Concomitant targeting of tumor cells and induction of T-cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer
    • Wang Q, Li SH, Wang H, et al. Concomitant targeting of tumor cells and induction of T-cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer. Cancer Res. 2012;72:4417-4428.
    • (2012) Cancer Res. , vol.72 , pp. 4417-4428
    • Wang, Q.1    Li, S.H.2    Wang, H.3
  • 13
    • 0034076307 scopus 로고    scopus 로고
    • Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets
    • Clynes RA, Towers TL, Presta LG, et al. Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets. Nat Med. 2000;6:443-446.
    • (2000) Nat Med. , vol.6 , pp. 443-446
    • Clynes, R.A.1    Towers, T.L.2    Presta, L.G.3
  • 14
    • 4444372733 scopus 로고    scopus 로고
    • Pilot study of the mechanism of action of preoperative trastuzumab in patients with primary operable breast tumors overexpressing HER2
    • Gennari R, Menard S, Fagnoni F, et al. Pilot study of the mechanism of action of preoperative trastuzumab in patients with primary operable breast tumors overexpressing HER2. Clin Cancer Res. 2004;10:5650-5655.
    • (2004) Clin Cancer Res. , vol.10 , pp. 5650-5655
    • Gennari, R.1    Menard, S.2    Fagnoni, F.3
  • 15
    • 77953141926 scopus 로고    scopus 로고
    • Superior in vivo efficacy of afucosylated trastuzumab in the treatment of HER2-amplified breast cancer
    • Junttila TT, Parsons K, Olsson C, et al. Superior in vivo efficacy of afucosylated trastuzumab in the treatment of HER2-amplified breast cancer. Cancer Res. 2010;70:4481-4489.
    • (2010) Cancer Res. , vol.70 , pp. 4481-4489
    • Junttila, T.T.1    Parsons, K.2    Olsson, C.3
  • 16
    • 42949157368 scopus 로고    scopus 로고
    • Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer
    • Musolino A, Naldi N, Bortesi B, et al. Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer. J Clin Oncol. 2008;26:1789-1796.
    • (2008) J Clin Oncol. , vol.26 , pp. 1789-1796
    • Musolino, A.1    Naldi, N.2    Bortesi, B.3
  • 17
    • 77955534002 scopus 로고    scopus 로고
    • The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity
    • Park S, Jiang Z, Mortenson ED, et al. The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity. Cancer Cell. 2010;18:160-170.
    • (2010) Cancer Cell. , vol.18 , pp. 160-170
    • Park, S.1    Jiang, Z.2    Mortenson, E.D.3
  • 18
    • 37549011436 scopus 로고    scopus 로고
    • Elements related to heterogeneity of antibody-dependent cell cytotoxicity in patients under trastuzumab therapy for primary operable breast cancer overexpressing Her2
    • Varchetta S, Gibelli N, Oliviero B, et al. Elements related to heterogeneity of antibody-dependent cell cytotoxicity in patients under trastuzumab therapy for primary operable breast cancer overexpressing Her2. Cancer Res. 2007;67:11991-11999.
    • (2007) Cancer Res. , vol.67 , pp. 11991-11999
    • Varchetta, S.1    Gibelli, N.2    Oliviero, B.3
  • 19
    • 79955570584 scopus 로고    scopus 로고
    • Anti-ERBB-2 mAb therapy requires type i and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy
    • Stagg J, Loi S, Divisekera U, et al. Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy. Proc Natl Acad Sci U S A. 2011;108:7142-7147.
    • (2011) Proc Natl Acad Sci U S A. , vol.108 , pp. 7142-7147
    • Stagg, J.1    Loi, S.2    Divisekera, U.3
  • 20
    • 84905178989 scopus 로고    scopus 로고
    • Tumor infiltrating lymphocytes are prognostic in triple negative breast cancer and predictive for trastuzumab benefit in early breast cancer: Results from the FinHER trial
    • Loi S, Michiels S, Salgado R, et al. Tumor infiltrating lymphocytes are prognostic in triple negative breast cancer and predictive for trastuzumab benefit in early breast cancer: results from the FinHER trial. Ann Oncol. 2014;25:1544-1550.
    • (2014) Ann Oncol. , vol.25 , pp. 1544-1550
    • Loi, S.1    Michiels, S.2    Salgado, R.3
  • 21
    • 80052236068 scopus 로고    scopus 로고
    • Human solid tumors contain high endothelial venules: Association with T- and B-lymphocyte infiltration and favorable prognosis in breast cancer
    • Martinet L, Garrido I, Filleron T, et al. Human solid tumors contain high endothelial venules: association with T- and B-lymphocyte infiltration and favorable prognosis in breast cancer. Cancer Res. 2011;71:5678-5687.
    • (2011) Cancer Res. , vol.71 , pp. 5678-5687
    • Martinet, L.1    Garrido, I.2    Filleron, T.3
  • 22
    • 84894514010 scopus 로고    scopus 로고
    • Characteristics of tertiary lymphoid structures in primary cancers
    • Goc J, Fridman WH, Sautes-Fridman C, et al. Characteristics of tertiary lymphoid structures in primary cancers. Oncoimmunology. 2013;2:e26836.
    • (2013) Oncoimmunology. , vol.2 , pp. e26836
    • Goc, J.1    Fridman, W.H.2    Sautes-Fridman, C.3
  • 23
    • 1942542931 scopus 로고    scopus 로고
    • Ligands for L-selectin: Homing, inflammation, and beyond
    • Rosen SD. Ligands for L-selectin: homing, inflammation, and beyond. Annu Rev Immunol. 2004;22:129-156.
    • (2004) Annu Rev Immunol. , vol.22 , pp. 129-156
    • Rosen, S.D.1
  • 24
    • 84899836282 scopus 로고    scopus 로고
    • Neo-antigens predicted by tumor genome meta-analysis correlate with increased patient survival
    • Brown SD, Warren RL, Gibb EA, et al. Neo-antigens predicted by tumor genome meta-analysis correlate with increased patient survival. Genome Res. 2014;24:743-750.
    • (2014) Genome Res. , vol.24 , pp. 743-750
    • Brown, S.D.1    Warren, R.L.2    Gibb, E.A.3
  • 25
    • 84988099642 scopus 로고
    • Can the HLA phenotype be used as a prognostic factor in breast carcinomas?
    • Concha A, Cabrera T, Ruiz-Cabello F, et al. Can the HLA phenotype be used as a prognostic factor in breast carcinomas? Int J Cancer Suppl. 1991;6:146-154.
    • (1991) Int J Cancer Suppl. , vol.6 , pp. 146-154
    • Concha, A.1    Cabrera, T.2    Ruiz-Cabello, F.3
  • 26
    • 78149287242 scopus 로고    scopus 로고
    • American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer
    • Hammond ME, Hayes DF, Wolff AC, et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer. J Oncol Pract. 2010;6:195-197.
    • (2010) J Oncol Pract. , vol.6 , pp. 195-197
    • Hammond, M.E.1    Hayes, D.F.2    Wolff, A.C.3
  • 27
    • 0032896905 scopus 로고    scopus 로고
    • Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer
    • Harvey JM, Clark GM, Osborne CK, et al. Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J Clin Oncol. 1999;17:1474-1481.
    • (1999) J Clin Oncol. , vol.17 , pp. 1474-1481
    • Harvey, J.M.1    Clark, G.M.2    Osborne, C.K.3
  • 28
    • 84890254448 scopus 로고    scopus 로고
    • Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update
    • Wolff AC, Hammond ME, Hicks DG, et al. Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update. Arch Pathol Lab Med. 2013;31:3997-4013.
    • (2013) Arch Pathol Lab Med. , vol.31 , pp. 3997-4013
    • Wolff, A.C.1    Hammond, M.E.2    Hicks, D.G.3
  • 29
    • 27744568370 scopus 로고    scopus 로고
    • Inflammation and prognosis in colorectal cancer
    • Klintrup K, Makinen JM, Kauppila S, et al. Inflammation and prognosis in colorectal cancer. Eur J Cancer. 2005;41:2645-2654.
    • (2005) Eur J Cancer. , vol.41 , pp. 2645-2654
    • Klintrup, K.1    Makinen, J.M.2    Kauppila, S.3
  • 30
    • 84924076132 scopus 로고    scopus 로고
    • Harmonization of the evaluation of tumor infiltrating lymphocytes (TILs) in breast cancer: Recommendations by an international TILs-working group 2014
    • Salgado R, Denkert C, Demaria S, et al. Harmonization of the evaluation of tumor infiltrating lymphocytes (TILs) in breast cancer: recommendations by an international TILs-working group 2014. Ann Oncol. 2015;26:259-271.
    • (2015) Ann Oncol. , vol.26 , pp. 259-271
    • Salgado, R.1    Denkert, C.2    Demaria, S.3
  • 31
    • 84860305582 scopus 로고    scopus 로고
    • Establishment of a monoclonal anti-pan HLA class i antibody suitable for immunostaining of formalin-fixed tissue: Unusually high frequency of down-regulation in breast cancer tissues
    • Torigoe T, Asanuma H, Nakazawa E, et al. Establishment of a monoclonal anti-pan HLA class I antibody suitable for immunostaining of formalin-fixed tissue: unusually high frequency of down-regulation in breast cancer tissues. Pathol Int. 2012;62:303-308.
    • (2012) Pathol Int. , vol.62 , pp. 303-308
    • Torigoe, T.1    Asanuma, H.2    Nakazawa, E.3
  • 32
    • 77954176769 scopus 로고    scopus 로고
    • A new pathological system for grading DCIS with improved prediction of local recurrence: Results from the UKCCCR/ANZ DCIS trial
    • Pinder SE, Duggan C, Ellis IO, et al. A new pathological system for grading DCIS with improved prediction of local recurrence: results from the UKCCCR/ANZ DCIS trial. Br J Cancer. 2010;103:94-100.
    • (2010) Br J Cancer. , vol.103 , pp. 94-100
    • Pinder, S.E.1    Duggan, C.2    Ellis, I.O.3
  • 33
    • 84879661529 scopus 로고    scopus 로고
    • CD4(+) follicular helper T cell infiltration predicts breast cancer survival
    • Gu-Trantien C, Loi S, Garaud S, et al. CD4(+) follicular helper T cell infiltration predicts breast cancer survival. J Clin Invest. 2013;123:2873-2892.
    • (2013) J Clin Invest. , vol.123 , pp. 2873-2892
    • Gu-Trantien, C.1    Loi, S.2    Garaud, S.3
  • 34
    • 84881421259 scopus 로고    scopus 로고
    • High endothelial venule blood vessels for tumor-infiltrating lymphocytes are associated with lymphotoxin beta-producing dendritic cells in human breast cancer
    • Martinet L, Filleron T, Le Guellec S, et al. High endothelial venule blood vessels for tumor-infiltrating lymphocytes are associated with lymphotoxin beta-producing dendritic cells in human breast cancer. J Immunol. 2013;191:2001-2008.
    • (2013) J Immunol. , vol.191 , pp. 2001-2008
    • Martinet, L.1    Filleron, T.2    Le Guellec, S.3
  • 35
    • 84908155711 scopus 로고    scopus 로고
    • Histopathological characterization of ductal carcinoma in situ (DCIS) of the breast according to HER2 amplification status and molecular subtype
    • Van Bockstal M, Lambein K, Denys H, et al. Histopathological characterization of ductal carcinoma in situ (DCIS) of the breast according to HER2 amplification status and molecular subtype. Virchows Arch. 2014;465:275-289.
    • (2014) Virchows Arch. , vol.465 , pp. 275-289
    • Van Bockstal, M.1    Lambein, K.2    Denys, H.3
  • 36
    • 84896957921 scopus 로고    scopus 로고
    • Occurrence of tertiary lymphoid tissue is associated with T-cell infiltration and predicts better prognosis in early-stage colorectal cancers
    • Di Caro G, Bergomas F, Grizzi F, et al. Occurrence of tertiary lymphoid tissue is associated with T-cell infiltration and predicts better prognosis in early-stage colorectal cancers. Clin Cancer Res. 2014;20:2147-2158.
    • (2014) Clin Cancer Res. , vol.20 , pp. 2147-2158
    • Di Caro, G.1    Bergomas, F.2    Grizzi, F.3
  • 37
    • 84886945668 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes, breast cancer subtypes and therapeutic efficacy
    • Loi S. Tumor-infiltrating lymphocytes, breast cancer subtypes and therapeutic efficacy. Oncoimmunology. 2013;2:e24720.
    • (2013) Oncoimmunology. , vol.2 , pp. e24720
    • Loi, S.1
  • 38
    • 84875191933 scopus 로고    scopus 로고
    • Expression of MHC class i on breast cancer cells correlates inversely with HER2 expression
    • Inoue M, Mimura K, Izawa S, et al. Expression of MHC class I on breast cancer cells correlates inversely with HER2 expression. Oncoimmunology. 2012;1:1104-1110.
    • (2012) Oncoimmunology. , vol.1 , pp. 1104-1110
    • Inoue, M.1    Mimura, K.2    Izawa, S.3


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