-
1
-
-
0022399581
-
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
-
PMID:2999974
-
Coussens L, Yang-Feng TL, Liao YC, Chen E, Gray A, McGrath J, et al. Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science 1985; 230:1132-9; PMID:2999974; http://dx.doi.org/10.1126/science. 2999974.
-
(1985)
Science
, vol.230
, pp. 1132-1139
-
-
Coussens, L.1
Yang-Feng, T.L.2
Liao, Y.C.3
Chen, E.4
Gray, A.5
McGrath, J.6
-
2
-
-
0034255737
-
HER-2/neu is expressed in human renal cell carcinoma at heterogeneous levels independently of tumor grading and staging and can be recognized by HLA-A2
-
PMID:10897039
-
Seliger B, Rongcun Y, Atkins D, Hammers S, Huber C, Störkel S, et al. HER-2/neu is expressed in human renal cell carcinoma at heterogeneous levels independently of tumor grading and staging and can be recognized by HLA-A2.1-restricted cytotoxic T lymphocytes. Int J Cancer 2000; 87:349-59; PMID:10897039.
-
(2000)
1-restricted cytotoxic T lymphocytes. Int J Cancer
, vol.87
, pp. 349-359
-
-
Seliger, B.1
Rongcun, Y.2
Atkins, D.3
Hammers, S.4
Huber, C.5
Störkel, S.6
-
3
-
-
18044376819
-
Frequencies of HER-2/neu expression and gene amplification in patients with oesophageal squamous cell carcinoma
-
PMID:15785739
-
Mimura K, Kono K, Hanawa M, Mitsui F, Sugai H, Miyagawa N, et al. Frequencies of HER-2/neu expression and gene amplification in patients with oesophageal squamous cell carcinoma. Br J Cancer 2005; 92:1253-60; PMID:15785739;http://dx.doi.org/10.1038/ sj.bjc.6602499
-
(2005)
Br J Cancer
, vol.92
, pp. 1253-1260
-
-
Mimura, K.1
Kono, K.2
Hanawa, M.3
Mitsui, F.4
Sugai, H.5
Miyagawa, N.6
-
4
-
-
34447339121
-
HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer
-
PMID:16882699
-
Al-Kuraya K, Novotny H, Bavi P, Siraj AK, Uddin S, Ezzat A, et al. HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer. J Clin Pathol 2007; 60:768-72; PMID:16882699; http://dx.doi.org/10.1136/jcp.2006.038281.
-
(2007)
J Clin Pathol
, vol.60
, pp. 768-772
-
-
Al-Kuraya, K.1
Novotny, H.2
Bavi, P.3
Siraj, A.K.4
Uddin, S.5
Ezzat, A.6
-
5
-
-
0037140070
-
Status of c-erbB-2 in gastric adenocarcinoma: a comparative study of immunohistochemistry, fluorescence in situ hybridization and enzyme-linked immuno-sorbent assay
-
PMID:11948459.
-
Takehana T, Kunitomo K, Kono K, Kitahara F, Iizuka H, Matsumoto Y, et al. Status of c-erbB-2 in gastric adenocarcinoma: a comparative study of immunohistochemistry, fluorescence in situ hybridization and enzyme-linked immuno-sorbent assay. Int J Cancer 2002; 98:833-7; PMID:11948459.
-
(2002)
Int J Cancer
, vol.98
, pp. 833-837
-
-
Takehana, T.1
Kunitomo, K.2
Kono, K.3
Kitahara, F.4
Iizuka, H.5
Matsumoto, Y.6
-
6
-
-
0029053749
-
Identification of an immunodominant peptide of HER-2/neu protooncogene recognized by ovarian tumor-specific cytotoxic T lymphocyte lines
-
PMID:7539040
-
Fisk B, Blevins TL, Wharton JT, Ioannides CG. Identification of an immunodominant peptide of HER-2/neu protooncogene recognized by ovarian tumor-specific cytotoxic T lymphocyte lines. J Exp Med 1995; 181:2109-17; PMID:7539040; http:// dx.doi.org/10.1084/jem.181.6.2109.
-
(1995)
J Exp Med
, vol.181
, pp. 2109-2117
-
-
Fisk, B.1
Blevins, T.L.2
Wharton, J.T.3
Ioannides, C.G.4
-
7
-
-
0031712512
-
Identification of HER2/neu-derived peptide epitopes recognized by gastric cancer-specific cytotoxic T lymphocytes
-
PMID:9754653.
-
Kono K, Rongcun Y, Charo J, Ichihara F, Celis E, Sette A, et al. Identification of HER2/neu-derived peptide epitopes recognized by gastric cancer-specific cytotoxic T lymphocytes. Int J Cancer 1998; 78:202-8; PMID:9754653.
-
(1998)
Int J Cancer
, vol.78
, pp. 202-208
-
-
Kono, K.1
Rongcun, Y.2
Charo, J.3
Ichihara, F.4
Celis, E.5
Sette, A.6
-
8
-
-
70350435441
-
Concurrent trastuzumab and HER2/ neu-specific vaccination in patients with metastatic breast cancer
-
PMID:19720923
-
Disis ML, Wallace DR, Gooley TA, Dang Y, Slota M, Lu H, et al. Concurrent trastuzumab and HER2/ neu-specific vaccination in patients with metastatic breast cancer. J Clin Oncol 2009; 27:4685-92; PMID:19720923; http://dx.doi.org/10.1200/ JCO.2008.20.6789.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4685-4692
-
-
Disis, M.L.1
Wallace, D.R.2
Gooley, T.A.3
Dang, Y.4
Slota, M.5
Lu, H.6
-
9
-
-
27144464759
-
Clinical trial results of a HER2/neu (E75) vaccine to prevent recurrence in high-risk breast cancer patients
-
PMID:16157940
-
Peoples GE, Gurney JM, Hueman MT, Woll MM, Ryan GB, Storrer CE, et al. Clinical trial results of a HER2/neu (E75) vaccine to prevent recurrence in high-risk breast cancer patients. J Clin Oncol 2005; 23:7536-45; PMID:16157940; http://dx.doi. org/10.1200/JCO.2005.03.047.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7536-7545
-
-
Peoples, G.E.1
Gurney, J.M.2
Hueman, M.T.3
Woll, M.M.4
Ryan, G.B.5
Storrer, C.E.6
-
10
-
-
65349097929
-
The impact of HER2/ neu expression level on response to the E75 vaccine: from US
-
PMID:19351776
-
Benavides LC, Gates JD, Carmichael MG, Patil R, Holmes JP, Hueman MT, et al. The impact of HER2/ neu expression level on response to the E75 vaccine: from U.S. Military Cancer Institute Clinical Trials Group Study I-01 and I-02. Clin Cancer Res 2009; 15:2895-904; PMID:19351776; http://dx.doi. org/10.1158/1078-0432.CCR-08-1126.
-
(2009)
Military Cancer Institute Clinical Trials Group Study I-01 and I-02. Clin Cancer Res
, vol.15
, pp. 2895-2904
-
-
Benavides, L.C.1
Gates, J.D.2
Carmichael, M.G.3
Patil, R.4
Holmes, J.P.5
Hueman, M.T.6
-
11
-
-
38949139497
-
Combined clinical trial results of a HER2/neu (E75) vaccine for the prevention of recurrence in high-risk breast cancer patients: USMilitary Cancer Institute Clinical Trials Group Study I-01 and I-02
-
PMID:18245541
-
Peoples GE, Holmes JP, Hueman MT, Mittendorf EA, Amin A, Khoo S, et al. Combined clinical trial results of a HER2/neu (E75) vaccine for the prevention of recurrence in high-risk breast cancer patients: USMilitary Cancer Institute Clinical Trials Group Study I-01 and I-02. Clin Cancer Res 2008; 14:797-803; PMID:18245541; http://dx.doi. org/10.1158/1078-0432.CCR-07-1448.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 797-803
-
-
Peoples, G.E.1
Holmes, J.P.2
Hueman, M.T.3
Mittendorf, E.A.4
Amin, A.5
Khoo, S.6
-
12
-
-
1642535582
-
HER-2/neu-mediated regulation of components of the MHC class I antigenprocessing pathway
-
PMID:14729627
-
Herrmann F, Lehr HA, Drexler I, Sutter G, Hengstler J, Wollscheid U, et al. HER-2/neu-mediated regulation of components of the MHC class I antigenprocessing pathway. Cancer Res 2004; 64:215-20; PMID:14729627; http://dx.doi.org/10.1158/0008-5472.CAN-2522-2.
-
(2004)
Cancer Res
, vol.64
, pp. 215-220
-
-
Herrmann, F.1
Lehr, H.A.2
Drexler, I.3
Sutter, G.4
Hengstler, J.5
Wollscheid, U.6
-
13
-
-
0031870766
-
Down-regulation of major histocompatibility complex class I expression in mammary carcinoma of HER-2/neu transgenic mice
-
PMID:9714068.
-
Lollini PL, Nicoletti G, Landuzzi L, De Giovanni C, Rossi I, Di Carlo E, et al. Down-regulation of major histocompatibility complex class I expression in mammary carcinoma of HER-2/neu transgenic mice. Int J Cancer 1998; 77:937-41; PMID:9714068.
-
(1998)
Int J Cancer
, vol.77
, pp. 937-941
-
-
Lollini, P.L.1
Nicoletti, G.2
Landuzzi, L.3
de Giovanni, C.4
Rossi, I.5
di Carlo, E.6
-
14
-
-
33644597584
-
Interferon-gamma renders tumors that express low levels of Her-2/neu sensitive to cytotoxic T cells
-
PMID:16151808
-
Kaplan BL, Norell H, Callender GG, Ohlum T, Kiessling R, Nishimura MI. Interferon-gamma renders tumors that express low levels of Her-2/neu sensitive to cytotoxic T cells. Cancer Immunol Immunother 2006; 55:653-62; PMID:16151808; http://dx.doi. org/10.1007/s00262-005-0050-5.
-
(2006)
Cancer Immunol Immunother
, vol.55
, pp. 653-662
-
-
Kaplan, B.L.1
Norell, H.2
Callender, G.G.3
Ohlum, T.4
Kiessling, R.5
Nishimura, M.I.6
-
15
-
-
78649581349
-
T cell recognition of HLA-A2 restricted tumor antigens is impaired by the oncogene HER2
-
PMID:20715101
-
Mimura K, Ando T, Poschke I, Mougiakakos D, Johansson CC, Ichikawa J, et al. T cell recognition of HLA-A2 restricted tumor antigens is impaired by the oncogene HER2. Int J Cancer 2011; 128:390-401; PMID:20715101; http://dx.doi.org/10.1002/ ijc.25613.
-
(2011)
Int J Cancer
, vol.128
, pp. 390-401
-
-
Mimura, K.1
Ando, T.2
Poschke, I.3
Mougiakakos, D.4
Johansson, C.C.5
Ichikawa, J.6
-
16
-
-
1242315584
-
Signal transduction and oncogenesis by ErbB/HER receptors
-
PMID:14967450
-
Marmor MD, Skaria KB, Yarden Y. Signal transduction and oncogenesis by ErbB/HER receptors. Int J Radiat Oncol Biol Phys 2004; 58:903-13; PMID:14967450; http://dx.doi.org/10.1016/j.ijrobp.2003.06.002.
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.58
, pp. 903-913
-
-
Marmor, M.D.1
Skaria, K.B.2
Yarden, Y.3
-
17
-
-
0344825125
-
Small interfering RNA (siRNA) inhibits the expression of the Her2/neu gene, upregulates HLA class I and induces apoptosis of Her2/neu positive tumor cell lines
-
PMID:14618618
-
Choudhury A, Charo J, Parapuram SK, Hunt RC, Hunt DM, Seliger B, et al. Small interfering RNA (siRNA) inhibits the expression of the Her2/neu gene, upregulates HLA class I and induces apoptosis of Her2/neu positive tumor cell lines. Int J Cancer 2004; 108:71-7; PMID:14618618; http://dx.doi. org/10.1002/ijc.11497.
-
(2004)
Int J Cancer
, vol.108
, pp. 71-77
-
-
Choudhury, A.1
Charo, J.2
Parapuram, S.K.3
Hunt, R.C.4
Hunt, D.M.5
Seliger, B.6
-
18
-
-
6944238452
-
Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway
-
PMID:15367412
-
DeGraffenried LA, Fulcher L, Friedrichs WE, Grünwald V, Ray RB, Hidalgo M. Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway. Ann Oncol 2004; 15:1510-6; PMID:15367412; http:// dx.doi.org/10.1093/annonc/mdh388.
-
(2004)
Ann Oncol
, vol.15
, pp. 1510-1516
-
-
DeGraffenried, L.A.1
Fulcher, L.2
Friedrichs, W.E.3
Grünwald, V.4
Ray, R.B.5
Hidalgo, M.6
-
19
-
-
5144226211
-
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
-
PMID:15324695
-
Nagata Y, Lan KH, Zhou X, Tan M, Esteva FJ, Sahin AA, et al. PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell 2004; 6:117-27; PMID:15324695; http://dx.doi. org/10.1016/j.ccr.2004.06.022.
-
(2004)
Cancer Cell
, vol.6
, pp. 117-127
-
-
Nagata, Y.1
Lan, K.H.2
Zhou, X.3
Tan, M.4
Esteva, F.J.5
Sahin, A.A.6
-
20
-
-
0032804162
-
Allelic loss of the PTEN region (10q23) in breast carcinomas of poor pathophenotype
-
PMID:10617300
-
Garcia JM, Silva JM, Dominguez G, Gonzalez R, Navarro A, Carretero L, et al. Allelic loss of the PTEN region (10q23) in breast carcinomas of poor pathophenotype. Breast Cancer Res Treat 1999; 57:237-43; PMID:10617300; http://dx.doi. org/10.1023/A:1006273516976.
-
(1999)
Breast Cancer Res Treat
, vol.57
, pp. 237-243
-
-
Garcia, J.M.1
Silva, J.M.2
Dominguez, G.3
Gonzalez, R.4
Navarro, A.5
Carretero, L.6
-
21
-
-
0035971181
-
Phosphatidylinositol-3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance
-
PMID:11139588
-
Campbell RA, Bhat-Nakshatri P, Patel NM, Constantinidou D, Ali S, Nakshatri H. Phosphatidylinositol-3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. J Biol Chem 2001; 276:9817-24; PMID:11139588; http://dx.doi.org/10.1074/jbc. M010840200.
-
(2001)
J Biol Chem
, vol.276
, pp. 9817-9824
-
-
Campbell, R.A.1
Bhat-Nakshatri, P.2
Patel, N.M.3
Constantinidou, D.4
Ali, S.5
Nakshatri, H.6
-
23
-
-
0032213456
-
Immunization with a peptide epitope (p369-377) from HER-2/neu leads to peptidespecific cytotoxic T lymphocytes that fail to recognize HER-2/neu+ tumors
-
PMID:9809997
-
Zaks TZ, Rosenberg SA. Immunization with a peptide epitope (p369-377) from HER-2/neu leads to peptidespecific cytotoxic T lymphocytes that fail to recognize HER-2/neu+ tumors. Cancer Res 1998; 58:4902-8; PMID:9809997.
-
(1998)
Cancer Res
, vol.58
, pp. 4902-4908
-
-
Zaks, T.Z.1
Rosenberg, S.A.2
-
24
-
-
50949133930
-
CTLs directed against HER2 specifically cross-react with HER3 and HER4
-
PMID:18523278
-
Conrad H, Gebhard K, Krönig H, Neudorfer J, Busch DH, Peschel C, et al. CTLs directed against HER2 specifically cross-react with HER3 and HER4. J Immunol 2008; 180:8135-45; PMID:18523278.
-
(2008)
J Immunol
, vol.180
, pp. 8135-8145
-
-
Conrad, H.1
Gebhard, K.2
Krönig, H.3
Neudorfer, J.4
Busch, D.H.5
Peschel, C.6
-
25
-
-
55249121137
-
Downregulation of HLA Class I molecules in the tumour is associated with a poor prognosis in patients with oesophageal squamous cell carcinoma
-
PMID:18841157
-
Mizukami Y, Kono K, Maruyama T, Watanabe M, Kawaguchi Y, Kamimura K, et al. Downregulation of HLA Class I molecules in the tumour is associated with a poor prognosis in patients with oesophageal squamous cell carcinoma. Br J Cancer 2008; 99:1462-7; PMID:18841157; http://dx.doi.org/10.1038/ sj.bjc.6604715.
-
(2008)
Br J Cancer
, vol.99
, pp. 1462-1467
-
-
Mizukami, Y.1
Kono, K.2
Maruyama, T.3
Watanabe, M.4
Kawaguchi, Y.5
Kamimura, K.6
-
26
-
-
50649087258
-
Molecular mechanisms of MHC class I abnormalities and APM components in human tumors
-
PMID:18408926
-
Seliger B. Molecular mechanisms of MHC class I abnormalities and APM components in human tumors. Cancer Immunol Immunother 2008; 57:1719-26; PMID:18408926; http://dx.doi.org/10.1007/s00262-008-0515-4.
-
(2008)
Cancer Immunol Immunother
, vol.57
, pp. 1719-1726
-
-
Seliger, B.1
-
27
-
-
77955512899
-
Inverse correlation of HER2 with MHC class I expression on oesophageal squamous cell carcinoma
-
PMID:20628381
-
Maruyama T, Mimura K, Sato E, Watanabe M, Mizukami Y, Kawaguchi Y, et al. Inverse correlation of HER2 with MHC class I expression on oesophageal squamous cell carcinoma. Br J Cancer 2010; 103:552-9; PMID:20628381; http://dx.doi.org/10.1038/ sj.bjc.6605772.
-
(2010)
Br J Cancer
, vol.103
, pp. 552-59
-
-
Maruyama, T.1
Mimura, K.2
Sato, E.3
Watanabe, M.4
Mizukami, Y.5
Kawaguchi, Y.6
-
28
-
-
77953036244
-
Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial
-
PMID:20529245
-
Norell H, Poschke I, Charo J, Wei WZ, Erskine C, Piechocki MP, et al. Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial. J Transl Med 2010; 8:53; PMID:20529245; http://dx.doi. org/10.1186/1479-5876-8-53.
-
(2010)
J Transl Med
, vol.8
, pp. 53
-
-
Norell, H.1
Poschke, I.2
Charo, J.3
Wei, W.Z.4
Erskine, C.5
Piechocki, M.P.6
-
29
-
-
77649173208
-
Lapatinib restores hormone sensitivity with differential effects on estrogen receptor signaling in cell models of human epidermal growth factor receptor 2-negative breast cancer with acquired endocrine resistance
-
PMID:20179226
-
Leary AF, Drury S, Detre S, Pancholi S, Lykkesfeldt AE, Martin LA, et al. Lapatinib restores hormone sensitivity with differential effects on estrogen receptor signaling in cell models of human epidermal growth factor receptor 2-negative breast cancer with acquired endocrine resistance. Clin Cancer Res 2010; 16:1486-97; PMID:20179226; http://dx.doi.org/10.1158/1078-0432.CCR-09-1764.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1486-1497
-
-
Leary, A.F.1
Drury, S.2
Detre, S.3
Pancholi, S.4
Lykkesfeldt, A.E.5
Martin, L.A.6
-
30
-
-
0030013525
-
Immunohistochemical expression of the c-kit proto-oncogene product in human malignant and non-malignant breast tissues
-
PMID:8630284
-
Chui X, Egami H, Yamashita J, Kurizaki T, Ohmachi H, Yamamoto S, et al. Immunohistochemical expression of the c-kit proto-oncogene product in human malignant and non-malignant breast tissues. Br J Cancer 1996; 73:1233-6; PMID:8630284; http:// dx.doi.org/10.1038/bjc.1996.236.
-
(1996)
Br J Cancer
, vol.73
, pp. 1233-1236
-
-
Chui, X.1
Egami, H.2
Yamashita, J.3
Kurizaki, T.4
Ohmachi, H.5
Yamamoto, S.6
-
31
-
-
66849140730
-
Ki67 index, HER2 status and prognosis of patients with luminal B breast cancer
-
PMID:19436038
-
Cheang MC, Chia SK, Voduc D, Gao D, Leung S, Snider J, et al. Ki67 index, HER2 status and prognosis of patients with luminal B breast cancer. J Natl Cancer Inst 2009; PMID:19436038; 101:736-50; http:// dx.doi.org/10.1093/jnci/djp082.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 736-750
-
-
Cheang, M.C.1
Chia, S.K.2
Voduc, D.3
Gao, D.4
Leung, S.5
Snider, J.6
|