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Volumn 15, Issue 1, 2015, Pages 1-11

Appropriate initial antibiotic therapy in hospitalized patients with gram-negative infections: Systematic review and meta-analysis

Author keywords

Appropriate initial antibiotic therapy; Gram negative; Healthcare associated; Hospital acquired; Inappropriate initial antibiotic therapy; Systematic review

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT;

EID: 84942581362     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/s12879-015-1123-5     Document Type: Article
Times cited : (93)

References (77)
  • 1
    • 84942672575 scopus 로고    scopus 로고
    • Available online: Accessed January 12
    • Healthcare-associated Infections (HAIs). HAI Prevalence Data and Statistics. Centers for Disease Control and Prevention website. Available online: http://www.cdc.gov/HAI/surveillance/index.html. Accessed January 12, 2015
    • (2015)
  • 2
    • 84870946642 scopus 로고    scopus 로고
    • Antimicrobial-resistant pathogens associated with healthcare-associated infections: summary of data reported to the national healthcare safety network at the centers for disease control and prevention, 2009-2010
    • Sievert DM, Ricks P, Edwards JR, Schneider A, Patel J, Srinivasan A, et al. Antimicrobial-resistant pathogens associated with healthcare-associated infections: summary of data reported to the national healthcare safety network at the centers for disease control and prevention, 2009-2010. Infect Control Hosp Epidemiol. 2013;34:1-14.
    • (2013) Infect Control Hosp Epidemiol , vol.34 , pp. 1-14
    • Sievert, D.M.1    Ricks, P.2    Edwards, J.R.3    Schneider, A.4    Patel, J.5    Srinivasan, A.6
  • 3
    • 80054953696 scopus 로고    scopus 로고
    • Combination antibiotic therapy for empiric and definitive treatment of gram-negative infections: insights from the society of infectious diseases pharmacists
    • Boyd N, Nailor MD. Combination antibiotic therapy for empiric and definitive treatment of gram-negative infections: insights from the society of infectious diseases pharmacists. Pharmacotherapy. 2011;31:1073-84.
    • (2011) Pharmacotherapy , vol.31 , pp. 1073-1084
    • Boyd, N.1    Nailor, M.D.2
  • 4
    • 33747179934 scopus 로고    scopus 로고
    • The beta-lactamase threat in Enterobacteriaceae, pseudomonas and acinetobacter
    • Livermore DM, Woodford N. The beta-lactamase threat in Enterobacteriaceae, pseudomonas and acinetobacter. Trends Microbiol. 2006;14:413-20.
    • (2006) Trends Microbiol , vol.14 , pp. 413-420
    • Livermore, D.M.1    Woodford, N.2
  • 5
    • 84889582557 scopus 로고    scopus 로고
    • Health care-associated infections: a meta-analysis of costs and financial impact on the US health care system
    • Zimlichman E, Henderson D, Tamir O, Franz C, Song P, Yamin CK, et al. Health care-associated infections: a meta-analysis of costs and financial impact on the US health care system. JAMA Intern Med. 2013;173:2039-46.
    • (2013) JAMA Intern Med , vol.173 , pp. 2039-2046
    • Zimlichman, E.1    Henderson, D.2    Tamir, O.3    Franz, C.4    Song, P.5    Yamin, C.K.6
  • 6
    • 84988850633 scopus 로고    scopus 로고
    • Clinical and economic consequences of hospital-acquired resistant and multidrug-resistant Pseudomonas aeruginosa infections: a systematic review and meta-analysis
    • Nathwani D, Raman G, Sulham K, Gavaghan M, Menon V. Clinical and economic consequences of hospital-acquired resistant and multidrug-resistant Pseudomonas aeruginosa infections: a systematic review and meta-analysis. Antimicrob Resist Infect Control. 2014;3:32.
    • (2014) Antimicrob Resist Infect Control , vol.3 , pp. 32
    • Nathwani, D.1    Raman, G.2    Sulham, K.3    Gavaghan, M.4    Menon, V.5
  • 7
    • 77955171857 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
    • Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ. 2010;8:336-41.
    • (2010) BMJ , vol.8 , pp. 336-341
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 10
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey SG, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315:629-34.
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey, S.G.2    Schneider, M.3    Minder, C.4
  • 12
    • 39049102555 scopus 로고    scopus 로고
    • Evaluation of risk factors for the acquisition of bloodstream infections with extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species in the intensive care unit; antibiotic management and clinical outcome
    • Cordery RJ, Roberts CH, Cooper SJ, Bellinghan G, Shetty N. Evaluation of risk factors for the acquisition of bloodstream infections with extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species in the intensive care unit; antibiotic management and clinical outcome. J Hosp Infect. 2008;68:108-15.
    • (2008) J Hosp Infect , vol.68 , pp. 108-115
    • Cordery, R.J.1    Roberts, C.H.2    Cooper, S.J.3    Bellinghan, G.4    Shetty, N.5
  • 13
    • 0036449283 scopus 로고    scopus 로고
    • Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae bloodstream infection: risk factors and clinical outcome
    • Du B, Long Y, Liu H, Chen D, Liu D, Xu Y, et al. Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae bloodstream infection: risk factors and clinical outcome. Intensive Care Med. 2002;28:1718-23.
    • (2002) Intensive Care Med , vol.28 , pp. 1718-1723
    • Du, B.1    Long, Y.2    Liu, H.3    Chen, D.4    Liu, D.5    Xu, Y.6
  • 14
    • 84870870303 scopus 로고    scopus 로고
    • The influence of carbapenem resistance on mortality in solid organ transplant recipients with Acinetobacter baumannii infection
    • de Gouvea EF, Martins IS, Halpern M, Ferreira AL, Basto ST, Goncalves RT, et al. The influence of carbapenem resistance on mortality in solid organ transplant recipients with Acinetobacter baumannii infection. BMC Infect Dis. 2012;12:351.
    • (2012) BMC Infect Dis , vol.12 , pp. 351
    • Gouvea, E.F.1    Martins, I.S.2    Halpern, M.3    Ferreira, A.L.4    Basto, S.T.5    Goncalves, R.T.6
  • 15
    • 77956023741 scopus 로고    scopus 로고
    • Acinetobacter pneumonia: Is the outcome different from the pneumonias caused by other agents
    • Edis EC, Hatipoglu ON, Tansel O, Sut N. Acinetobacter pneumonia: Is the outcome different from the pneumonias caused by other agents. Ann Thoracic Med. 2010;5:92-6.
    • (2010) Ann Thoracic Med , vol.5 , pp. 92-96
    • Edis, E.C.1    Hatipoglu, O.N.2    Tansel, O.3    Sut, N.4
  • 16
    • 70350412317 scopus 로고    scopus 로고
    • Impact of early appropriate antimicrobial therapy on survival in Acinetobacter baumannii bloodstream infections
    • Erbay A, Idil A, Gozel MG, Mumcuoglu I, Balaban N. Impact of early appropriate antimicrobial therapy on survival in Acinetobacter baumannii bloodstream infections. Int J Antimicrob Agents. 2009;34:575-9.
    • (2009) Int J Antimicrob Agents , vol.34 , pp. 575-579
    • Erbay, A.1    Idil, A.2    Gozel, M.G.3    Mumcuoglu, I.4    Balaban, N.5
  • 17
    • 33749170489 scopus 로고    scopus 로고
    • Comparison of mortality of patients with Acinetobacter baumannii bacteraemia receiving appropriate and inappropriate empirical therapy
    • Falagas ME, Kasiakou SK, Rafailidis PI, Zouglakis G, Morfou P. Comparison of mortality of patients with Acinetobacter baumannii bacteraemia receiving appropriate and inappropriate empirical therapy. J Antimicrob Chemother. 2006;57:1251-4.
    • (2006) J Antimicrob Chemother , vol.57 , pp. 1251-1254
    • Falagas, M.E.1    Kasiakou, S.K.2    Rafailidis, P.I.3    Zouglakis, G.4    Morfou, P.5
  • 18
    • 34547700428 scopus 로고    scopus 로고
    • Optimal management therapy for Pseudomonas aeruginosa ventilator-associated pneumonia: an observational, multicenter study comparing monotherapy with combination antibiotic therapy
    • Garnacho-Montero J, Sa-Borges M, Sole-Violan J, Barcenilla F, Escoresca-Ortega A, Ochoa M, et al. Optimal management therapy for Pseudomonas aeruginosa ventilator-associated pneumonia: an observational, multicenter study comparing monotherapy with combination antibiotic therapy. Crit Care Med. 2007;35:1888-95.
    • (2007) Crit Care Med , vol.35 , pp. 1888-1895
    • Garnacho-Montero, J.1    Sa-Borges, M.2    Sole-Violan, J.3    Barcenilla, F.4    Escoresca-Ortega, A.5    Ochoa, M.6
  • 19
    • 84868316904 scopus 로고    scopus 로고
    • Risk factors for mortality in patients with nosocomial gram-negative bacteremia
    • Gozel M, Erbay A, Bodur H, Eren S, Balaban N. Risk factors for mortality in patients with nosocomial gram-negative bacteremia. Turkiye Klinikleri J Med Sci. 2012;32:1641-7.
    • (2012) Turkiye Klinikleri J Med Sci , vol.32 , pp. 1641-1647
    • Gozel, M.1    Erbay, A.2    Bodur, H.3    Eren, S.4    Balaban, N.5
  • 20
    • 84866593987 scopus 로고    scopus 로고
    • Risk factors and clinical outcomes of patients with carbapenem-resistant Acinetobacter baumannii bacteremia
    • Huang ST, Chiang MC, Kuo SC, Lee YT, Chiang TH, Yang SP, et al. Risk factors and clinical outcomes of patients with carbapenem-resistant Acinetobacter baumannii bacteremia. J Microbiol Immunol Infect. 2012;45:356-62.
    • (2012) J Microbiol Immunol Infect , vol.45 , pp. 356-362
    • Huang, S.T.1    Chiang, M.C.2    Kuo, S.C.3    Lee, Y.T.4    Chiang, T.H.5    Yang, S.P.6
  • 21
    • 63449141214 scopus 로고    scopus 로고
    • Attributable mortality of imipenem-resistant nosocomial Acinetobacter baumannii bloodstream infection
    • Jamulitrat S, Arunpan P, Phainuphong P. Attributable mortality of imipenem-resistant nosocomial Acinetobacter baumannii bloodstream infection. J Med Assoc Thai. 2009;92:413-9.
    • (2009) J Med Assoc Thai , vol.92 , pp. 413-419
    • Jamulitrat, S.1    Arunpan, P.2    Phainuphong, P.3
  • 22
    • 77955662258 scopus 로고    scopus 로고
    • Impact of inappropriate antimicrobial therapy on outcome in patients with hospital-acquired pneumonia caused by Acinetobacter baumannii
    • Joung MK, Kwon KT, Kang CI, Cheong HS, Rhee JY, Jung DS, et al. Impact of inappropriate antimicrobial therapy on outcome in patients with hospital-acquired pneumonia caused by Acinetobacter baumannii. J Infect. 2010;61:212-8.
    • (2010) J Infect , vol.61 , pp. 212-218
    • Joung, M.K.1    Kwon, K.T.2    Kang, C.I.3    Cheong, H.S.4    Rhee, J.Y.5    Jung, D.S.6
  • 23
    • 12944295224 scopus 로고    scopus 로고
    • Bloodstream infections caused by antibiotic-resistant gram-negative bacilli: risk factors for mortality and impact of inappropriate initial antimicrobial therapy on outcome
    • Kang CI, Kim SH, Park WB, Lee KD, Kim HB, Kim EC, et al. Bloodstream infections caused by antibiotic-resistant gram-negative bacilli: risk factors for mortality and impact of inappropriate initial antimicrobial therapy on outcome. Antimicrob Agents Chemother. 2005;49:760-6.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 760-766
    • Kang, C.I.1    Kim, S.H.2    Park, W.B.3    Lee, K.D.4    Kim, H.B.5    Kim, E.C.6
  • 24
    • 84862902944 scopus 로고    scopus 로고
    • Risk factors for mortality in patients with carbapenem-resistant Acinetobacter baumannii bacteremia: impact of appropriate antimicrobial therapy
    • Kim YJ, Kim SI, Hong KW, Kim YR, Park YJ, Kang MW. Risk factors for mortality in patients with carbapenem-resistant Acinetobacter baumannii bacteremia: impact of appropriate antimicrobial therapy. J Korean Med Sci. 2012;27:471-5.
    • (2012) J Korean Med Sci , vol.27 , pp. 471-475
    • Kim, Y.J.1    Kim, S.I.2    Hong, K.W.3    Kim, Y.R.4    Park, Y.J.5    Kang, M.W.6
  • 25
    • 49449085432 scopus 로고    scopus 로고
    • Predictors of 30-day mortality and hospital costs in patients with ventilator-associated pneumonia attributed to potentially antibiotic-resistant gram-negative bacteria
    • Kollef KE, Schramm GE, Wills AR, Reichley RM, Micek ST, Kollef MH. Predictors of 30-day mortality and hospital costs in patients with ventilator-associated pneumonia attributed to potentially antibiotic-resistant gram-negative bacteria. Chest. 2008;134:281-7.
    • (2008) Chest , vol.134 , pp. 281-287
    • Kollef, K.E.1    Schramm, G.E.2    Wills, A.R.3    Reichley, R.M.4    Micek, S.T.5    Kollef, M.H.6
  • 26
    • 84878929109 scopus 로고    scopus 로고
    • Evaluation of the effect of appropriate antimicrobial therapy on mortality associated with Acinetobacter nosocomialis bacteraemia
    • Kuo SC, Lee YT, Yang SP, Chiang MC, Lin YT, Tseng FC, et al. Evaluation of the effect of appropriate antimicrobial therapy on mortality associated with Acinetobacter nosocomialis bacteraemia. Clin Microbiol Infect. 2013;19:634-9.
    • (2013) Clin Microbiol Infect , vol.19 , pp. 634-639
    • Kuo, S.C.1    Lee, Y.T.2    Yang, S.P.3    Chiang, M.C.4    Lin, Y.T.5    Tseng, F.C.6
  • 27
    • 84899586272 scopus 로고    scopus 로고
    • Risk factors and outcome analysis of acinetobacter baumannii complex bacteremia in critical patients
    • Lee HY, Chen CL, Wu SR, Huang CW, Chiu CH. Risk factors and outcome analysis of acinetobacter baumannii complex bacteremia in critical patients. Crit Care Med. 2014;42:1081-8.
    • (2014) Crit Care Med , vol.42 , pp. 1081-1088
    • Lee, H.Y.1    Chen, C.L.2    Wu, S.R.3    Huang, C.W.4    Chiu, C.H.5
  • 28
    • 70849130952 scopus 로고    scopus 로고
    • Clinical and microbiological analysis of Elizabethkingia meningoseptica bacteremia in adult patients in Taiwan
    • Lin YT, Chiu CH, Chan YJ, Lin ML, Yu KW, Wang FD, et al. Clinical and microbiological analysis of Elizabethkingia meningoseptica bacteremia in adult patients in Taiwan. Scand J Infect Dis. 2009;41:628-34.
    • (2009) Scand J Infect Dis , vol.41 , pp. 628-634
    • Lin, Y.T.1    Chiu, C.H.2    Chan, Y.J.3    Lin, M.L.4    Yu, K.W.5    Wang, F.D.6
  • 29
    • 79960468376 scopus 로고    scopus 로고
    • Nosocomial Klebsiella pneumoniae bacteraemia in adult cancer patients--characteristics of neutropenic and non-neutropenic patients
    • Lin YT, Liu CJ, Fung CP, Tzeng CH. Nosocomial Klebsiella pneumoniae bacteraemia in adult cancer patients--characteristics of neutropenic and non-neutropenic patients. Scand J Infect Dis. 2011;43:603-8.
    • (2011) Scand J Infect Dis , vol.43 , pp. 603-608
    • Lin, Y.T.1    Liu, C.J.2    Fung, C.P.3    Tzeng, C.H.4
  • 30
    • 34948821753 scopus 로고    scopus 로고
    • Predictors of 30-day mortality among patients with Pseudomonas aeruginosa bloodstream infections: impact of delayed appropriate antibiotic selection
    • Lodise Jr TP, Patel N, Kwa A, Graves J, Furuno JP, Graffunder E, et al. Predictors of 30-day mortality among patients with Pseudomonas aeruginosa bloodstream infections: impact of delayed appropriate antibiotic selection. Antimicrob Agents Chemother. 2007;51:3510-5.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 3510-3515
    • Lodise, T.P.1    Patel, N.2    Kwa, A.3    Graves, J.4    Furuno, J.P.5    Graffunder, E.6
  • 31
    • 84859911288 scopus 로고    scopus 로고
    • The impact of multidrug resistance in healthcare-associated and nosocomial Gram-negative bacteraemia on mortality and length of stay: cohort study
    • Lye DC, Earnest A, Ling ML, Lee TE, Yong HC, Fisher DA, et al. The impact of multidrug resistance in healthcare-associated and nosocomial Gram-negative bacteraemia on mortality and length of stay: cohort study. Clin Microbiol Infect. 2012;18:502-8.
    • (2012) Clin Microbiol Infect , vol.18 , pp. 502-508
    • Lye, D.C.1    Earnest, A.2    Ling, M.L.3    Lee, T.E.4    Yong, H.C.5    Fisher, D.A.6
  • 33
    • 24044447840 scopus 로고    scopus 로고
    • Clinical outcomes and therapeutic options of bloodstream infections caused by extended-spectrum beta-lactamase-producing Escherichia coli
    • Metan G, Zarakolu P, Cakir B, Hascelik G, Uzun O. Clinical outcomes and therapeutic options of bloodstream infections caused by extended-spectrum beta-lactamase-producing Escherichia coli. Int J Antimicrob Agents. 2005;26:254-7.
    • (2005) Int J Antimicrob Agents , vol.26 , pp. 254-257
    • Metan, G.1    Zarakolu, P.2    Cakir, B.3    Hascelik, G.4    Uzun, O.5
  • 34
    • 68949194579 scopus 로고    scopus 로고
    • Factors influencing survival in patients with multi-drug-resistant Acinetobacter bacteraemia
    • Metan G, Sariguzel F, Sumerkan B. Factors influencing survival in patients with multi-drug-resistant Acinetobacter bacteraemia. Eur J Intern Med. 2009;20:540-4.
    • (2009) Eur J Intern Med , vol.20 , pp. 540-544
    • Metan, G.1    Sariguzel, F.2    Sumerkan, B.3
  • 35
    • 84876706549 scopus 로고    scopus 로고
    • Factors influencing the early mortality in haematological malignancy patients with nosocomial Gram negative bacilli bacteraemia: a retrospective analysis of 154 cases
    • Metan G, Demiraslan H, Kaynar LG, Zararsiz G, Alp E, Eser B. Factors influencing the early mortality in haematological malignancy patients with nosocomial Gram negative bacilli bacteraemia: a retrospective analysis of 154 cases. Braz J Infect Dis. 2013;17:143-9.
    • (2013) Braz J Infect Dis , vol.17 , pp. 143-149
    • Metan, G.1    Demiraslan, H.2    Kaynar, L.G.3    Zararsiz, G.4    Alp, E.5    Eser, B.6
  • 38
    • 84861885387 scopus 로고    scopus 로고
    • The excess financial burden of multidrug resistance in severe gram-negative infections in Singaporean hospitals
    • Ng E, Earnest A, Lye DC, Ling ML, Ding Y, Hsu LY. The excess financial burden of multidrug resistance in severe gram-negative infections in Singaporean hospitals. Ann Acad Med Singap. 2012;41:189-93.
    • (2012) Ann Acad Med Singap , vol.41 , pp. 189-193
    • Ng, E.1    Earnest, A.2    Lye, D.C.3    Ling, M.L.4    Ding, Y.5    Hsu, L.Y.6
  • 39
    • 84878656341 scopus 로고    scopus 로고
    • The clinical characteristics, carbapenem resistance, and outcome of Acinetobacter bacteremia according to genospecies
    • Park KH, Shin JH, Lee SY, Kim SH, Jang MO, Kang SJ, et al. The clinical characteristics, carbapenem resistance, and outcome of Acinetobacter bacteremia according to genospecies. PLoS ONE [Electronic Resource]. 2013;8:e65026.
    • (2013) PLoS ONE [Electronic Resource] , vol.8 , pp. e65026
    • Park, K.H.1    Shin, J.H.2    Lee, S.Y.3    Kim, S.H.4    Jang, M.O.5    Kang, S.J.6
  • 40
    • 39049155380 scopus 로고    scopus 로고
    • Infections due to Escherichia coli producing extended-spectrum beta-lactamase among hospitalised patients: factors influencing mortality
    • Pena C, Gudiol C, Calatayud L, Tubau F, Dominguez MA, Pujol M, et al. Infections due to Escherichia coli producing extended-spectrum beta-lactamase among hospitalised patients: factors influencing mortality. J Hosp Infect. 2008;68:116-22.
    • (2008) J Hosp Infect , vol.68 , pp. 116-122
    • Pena, C.1    Gudiol, C.2    Calatayud, L.3    Tubau, F.4    Dominguez, M.A.5    Pujol, M.6
  • 41
    • 84874113830 scopus 로고    scopus 로고
    • Impact of multidrug resistance on Pseudomonas aeruginosa ventilator-associated pneumonia outcome: predictors of early and crude mortality
    • Pena C, Gomez-Zorrilla S, Oriol I, Tubau F, Dominguez MA, Pujol M, et al. Impact of multidrug resistance on Pseudomonas aeruginosa ventilator-associated pneumonia outcome: predictors of early and crude mortality. Eur J Clin Microbiol. 2013;32:413-20.
    • (2013) Eur J Clin Microbiol , vol.32 , pp. 413-420
    • Pena, C.1    Gomez-Zorrilla, S.2    Oriol, I.3    Tubau, F.4    Dominguez, M.A.5    Pujol, M.6
  • 42
    • 77951811232 scopus 로고    scopus 로고
    • Risk factors and prognosis of nosocomial bloodstream infections caused by extended-spectrum-beta-lactamase-producing Escherichia coli
    • Rodriguez-Bano J, Picon E, Gijon P, Hernandez JR, Cisneros JM, Pena C, et al. Risk factors and prognosis of nosocomial bloodstream infections caused by extended-spectrum-beta-lactamase-producing Escherichia coli. J Clin Microbiol. 2010;48:1726-31.
    • (2010) J Clin Microbiol , vol.48 , pp. 1726-1731
    • Rodriguez-Bano, J.1    Picon, E.2    Gijon, P.3    Hernandez, J.R.4    Cisneros, J.M.5    Pena, C.6
  • 43
    • 84924621522 scopus 로고    scopus 로고
    • Clinical characteristics and risk factors for mortality in cefepime-resistant Pseudomonas aeruginosa bacteremia
    • Su TY, Ye JJ, Hsu PC, Wu HF, Chia JH, Lee MH. Clinical characteristics and risk factors for mortality in cefepime-resistant Pseudomonas aeruginosa bacteremia. J Microbiol Immunol Infect. 2015;48:175-82.
    • (2015) J Microbiol Immunol Infect , vol.48 , pp. 175-182
    • Su, T.Y.1    Ye, J.J.2    Hsu, P.C.3    Wu, H.F.4    Chia, J.H.5    Lee, M.H.6
  • 45
    • 54949128320 scopus 로고    scopus 로고
    • Controlling for severity of illness in outcome studies involving infectious diseases: impact of measurement at different time points
    • Thom KA, Shardell MD, Osih RB, Schweizer ML, Furuno JP, Perencevich EN, et al. Controlling for severity of illness in outcome studies involving infectious diseases: impact of measurement at different time points. Infect Control Hosp Epidemiol. 2008;29:1048-53.
    • (2008) Infect Control Hosp Epidemiol , vol.29 , pp. 1048-1053
    • Thom, K.A.1    Shardell, M.D.2    Osih, R.B.3    Schweizer, M.L.4    Furuno, J.P.5    Perencevich, E.N.6
  • 46
    • 52949098803 scopus 로고    scopus 로고
    • Impact of empiric antimicrobial therapy on outcomes in patients with Escherichia coli and Klebsiella pneumoniae bacteremia: a cohort study
    • Thom KA, Schweizer ML, Osih RB, McGregor JC, Furuno JP, Perencevich EN, et al. Impact of empiric antimicrobial therapy on outcomes in patients with Escherichia coli and Klebsiella pneumoniae bacteremia: a cohort study. BMC Infect Dis. 2008;8:116.
    • (2008) BMC Infect Dis , vol.8 , pp. 116
    • Thom, K.A.1    Schweizer, M.L.2    Osih, R.B.3    McGregor, J.C.4    Furuno, J.P.5    Perencevich, E.N.6
  • 47
    • 84866072596 scopus 로고    scopus 로고
    • Predictors of mortality in bloodstream infections caused by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae: importance of combination therapy
    • Tumbarello M, Viale P, Viscoli C, Trecarichi EM, Tumietto F, Marchese A, et al. Predictors of mortality in bloodstream infections caused by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae: importance of combination therapy. Clin Infect Dis. 2012;55:943-50.
    • (2012) Clin Infect Dis , vol.55 , pp. 943-950
    • Tumbarello, M.1    Viale, P.2    Viscoli, C.3    Trecarichi, E.M.4    Tumietto, F.5    Marchese, A.6
  • 50
    • 84864364922 scopus 로고    scopus 로고
    • Risk factors for pan-resistant Pseudomonas aeruginosa bacteremia and the adequacy of antibiotic therapy
    • Tuon FF, Gortz LW, Rocha JL. Risk factors for pan-resistant Pseudomonas aeruginosa bacteremia and the adequacy of antibiotic therapy. Braz J Infect Dis. 2012;16:351-6.
    • (2012) Braz J Infect Dis , vol.16 , pp. 351-356
    • Tuon, F.F.1    Gortz, L.W.2    Rocha, J.L.3
  • 52
    • 84880012470 scopus 로고    scopus 로고
    • Comparison between bacteremia caused by carbapenem resistant Acinetobacter baumannii and Acinetobacter nosocomialis
    • Yang YS, Lee YT, Tsai WC, Kuo SC, Sun JR, Yang CH, et al. Comparison between bacteremia caused by carbapenem resistant Acinetobacter baumannii and Acinetobacter nosocomialis. BMC Infect Dis. 2013;13:311.
    • (2013) BMC Infect Dis , vol.13 , pp. 311
    • Yang, Y.S.1    Lee, Y.T.2    Tsai, W.C.3    Kuo, S.C.4    Sun, J.R.5    Yang, C.H.6
  • 53
    • 81255171675 scopus 로고    scopus 로고
    • Predictors of mortality in patients with bloodstream infections caused by KPC-producing Klebsiella pneumoniae and impact of appropriate antimicrobial treatment
    • Zarkotou O, Pournaras S, Tselioti P, Dragoumanos V, Pitiriga V, Ranellou K, et al. Predictors of mortality in patients with bloodstream infections caused by KPC-producing Klebsiella pneumoniae and impact of appropriate antimicrobial treatment. Clin Microbiol Infect. 2011;17:1798-803.
    • (2011) Clin Microbiol Infect , vol.17 , pp. 1798-1803
    • Zarkotou, O.1    Pournaras, S.2    Tselioti, P.3    Dragoumanos, V.4    Pitiriga, V.5    Ranellou, K.6
  • 54
    • 47549109407 scopus 로고    scopus 로고
    • Predictors of mortality from community-onset bloodstream infections due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae
    • Apisarnthanarak A, Kiratisin P, Mundy LM. Predictors of mortality from community-onset bloodstream infections due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae. Infect Control Hosp Epidemiol. 2008;29:671-4.
    • (2008) Infect Control Hosp Epidemiol , vol.29 , pp. 671-674
    • Apisarnthanarak, A.1    Kiratisin, P.2    Mundy, L.M.3
  • 55
    • 84879724442 scopus 로고    scopus 로고
    • Prevalence and risk factor analysis of resistant Escherichia coli urinary tract infections in the emergency department
    • Bailey AM, Weant KA, Baker SN. Prevalence and risk factor analysis of resistant Escherichia coli urinary tract infections in the emergency department. Pharm Pract. 2013;11:96-101.
    • (2013) Pharm Pract , vol.11 , pp. 96-101
    • Bailey, A.M.1    Weant, K.A.2    Baker, S.N.3
  • 56
    • 33645759039 scopus 로고    scopus 로고
    • Importance of appropriateness of empiric antibiotic therapy on clinical outcomes in intra-abdominal infections
    • Bare M, Castells X, Garcia A, Riu M, Comas M, Egea MJ. Importance of appropriateness of empiric antibiotic therapy on clinical outcomes in intra-abdominal infections. Int J Technol Assess Health Care. 2006;22:242-8.
    • (2006) Int J Technol Assess Health Care , vol.22 , pp. 242-248
    • Bare, M.1    Castells, X.2    Garcia, A.3    Riu, M.4    Comas, M.5    Egea, M.J.6
  • 57
    • 0035871033 scopus 로고    scopus 로고
    • Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae: risk factors for infection and impact of resistance on outcomes
    • Lautenbach E, Patel JB, Bilker WB, Edelstein PH, Fishman NO. Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae: risk factors for infection and impact of resistance on outcomes. Clin Infect Dis. 2001;32:1162-71.
    • (2001) Clin Infect Dis , vol.32 , pp. 1162-1171
    • Lautenbach, E.1    Patel, J.B.2    Bilker, W.B.3    Edelstein, P.H.4    Fishman, N.O.5
  • 58
    • 34250791128 scopus 로고    scopus 로고
    • Clinical and economic impact of multidrug resistance in nosocomial Acinetobacter baumannii bacteremia
    • Lee NY, Lee HC, Ko NY, Chang CM, Shih HI, Wu CJ, et al. Clinical and economic impact of multidrug resistance in nosocomial Acinetobacter baumannii bacteremia. Infect Control Hosp Epidemiol. 2007;28:713-9.
    • (2007) Infect Control Hosp Epidemiol , vol.28 , pp. 713-719
    • Lee, N.Y.1    Lee, H.C.2    Ko, N.Y.3    Chang, C.M.4    Shih, H.I.5    Wu, C.J.6
  • 59
    • 79551605326 scopus 로고    scopus 로고
    • Impact of discordant empirical therapy on outcome of community-acquired bacteremic acute pyelonephritis
    • Lee SS, Kim Y, Chung DR. Impact of discordant empirical therapy on outcome of community-acquired bacteremic acute pyelonephritis. J Infect. 2011;62:159-64.
    • (2011) J Infect , vol.62 , pp. 159-164
    • Lee, S.S.1    Kim, Y.2    Chung, D.R.3
  • 60
    • 84898602351 scopus 로고    scopus 로고
    • Impact of extended-spectrum beta-lactamase-producing organisms on clinical and economic outcomes in patients with urinary tract infection
    • MacVane SH, Tuttle LO, Nicolau DP. Impact of extended-spectrum beta-lactamase-producing organisms on clinical and economic outcomes in patients with urinary tract infection. J Hosp Med (Online). 2014;9:232-8.
    • (2014) J Hosp Med (Online) , vol.9 , pp. 232-238
    • MacVane, S.H.1    Tuttle, L.O.2    Nicolau, D.P.3
  • 64
    • 26444601973 scopus 로고    scopus 로고
    • Inappropriate initial treatment of secondary intra-abdominal infections leads to increased risk of clinical failure and costs
    • Sturkenboom MC, Goettsch WG, Picelli G, in 't Veld B, Yin DD, De Jong RB, et al. Inappropriate initial treatment of secondary intra-abdominal infections leads to increased risk of clinical failure and costs. Br J Clin Pharmacol. 2005;60:438-43.
    • (2005) Br J Clin Pharmacol , vol.60 , pp. 438-443
    • Sturkenboom, M.C.1    Goettsch, W.G.2    Picelli, G.3    In't Veld, B.4    Yin, D.D.5    Jong, R.B.6
  • 65
    • 77957336334 scopus 로고    scopus 로고
    • Costs of bloodstream infections caused by Escherichia coli and influence of extended-spectrum-beta-lactamase production and inadequate initial antibiotic therapy
    • Tumbarello M, Spanu T, Di BR, Marchetti M, Ruggeri M, Trecarichi EM, et al. Costs of bloodstream infections caused by Escherichia coli and influence of extended-spectrum-beta-lactamase production and inadequate initial antibiotic therapy. Antimicrob Agents Chemother. 2010;54:4085-91.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 4085-4091
    • Tumbarello, M.1    Spanu, T.2    Di, B.R.3    Marchetti, M.4    Ruggeri, M.5    Trecarichi, E.M.6
  • 66
    • 77953097553 scopus 로고    scopus 로고
    • Impact of Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae on the outcome of community-onset bacteremic urinary tract infections
    • Yang YS, Ku CH, Lin JC, Shang ST, Chiu CH, Yeh KM, et al. Impact of Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae on the outcome of community-onset bacteremic urinary tract infections. J Microbiol Immunol Infect. 2010;43:194-9.
    • (2010) J Microbiol Immunol Infect , vol.43 , pp. 194-199
    • Yang, Y.S.1    Ku, C.H.2    Lin, J.C.3    Shang, S.T.4    Chiu, C.H.5    Yeh, K.M.6
  • 67
    • 84864235202 scopus 로고    scopus 로고
    • Using the rate of bacterial clearance determined by real-time polymerase chain reaction as a timely surrogate marker to evaluate the appropriateness of antibiotic usage in critical patients with Acinetobacter baumannii bacteremia
    • Chuang YC, Chang SC, Wang WK. Using the rate of bacterial clearance determined by real-time polymerase chain reaction as a timely surrogate marker to evaluate the appropriateness of antibiotic usage in critical patients with Acinetobacter baumannii bacteremia. [Erratum appears in Crit Care Med. 2012;40(10):2932]. Crit Care Med 2012, 40:2273-2280.
    • (2012) [Erratum appears in Crit Care Med , vol.40 , Issue.10 , pp. 2932
    • Chuang, Y.C.1    Chang, S.C.2    Wang, W.K.3
  • 68
    • 84866656640 scopus 로고    scopus 로고
    • Treatment outcomes in patients with third-generation cephalosporin-resistant Enterobacter bacteremia
    • O'Neal CS, O'Neal HR, Daniels TL, Talbot TR. Treatment outcomes in patients with third-generation cephalosporin-resistant Enterobacter bacteremia. Scandinavian J Infect Dis. 2012;44:726-32.
    • (2012) Scandinavian J Infect Dis , vol.44 , pp. 726-732
    • O'Neal, C.S.1    O'Neal, H.R.2    Daniels, T.L.3    Talbot, T.R.4
  • 69
    • 79960044046 scopus 로고    scopus 로고
    • Clinical outcomes of patients infected with carbapenem-resistant Acinetobacter baumannii treated with single or combination antibiotic therapy
    • Santimaleeworagun W, Wongpoowarak P, Chayakul P, Pattharachayakul S, Tansakul P, Garey KW. Clinical outcomes of patients infected with carbapenem-resistant Acinetobacter baumannii treated with single or combination antibiotic therapy. J Med Assoc Thai. 2011;94:863-70.
    • (2011) J Med Assoc Thai , vol.94 , pp. 863-870
    • Santimaleeworagun, W.1    Wongpoowarak, P.2    Chayakul, P.3    Pattharachayakul, S.4    Tansakul, P.5    Garey, K.W.6
  • 70
    • 84873742512 scopus 로고    scopus 로고
    • De-escalation of antimicrobial therapy for bacteraemia due to difficult-to-treat Gram-negative bacilli
    • Shime N, Kosaka T, Fujita N. De-escalation of antimicrobial therapy for bacteraemia due to difficult-to-treat Gram-negative bacilli. Infection. 2013;41:203-10.
    • (2013) Infection , vol.41 , pp. 203-210
    • Shime, N.1    Kosaka, T.2    Fujita, N.3
  • 71
    • 77957980707 scopus 로고    scopus 로고
    • Origins and evolution of antibiotic resistance
    • Davies J, Davies D. Origins and evolution of antibiotic resistance. Microbiol Mol Biol Rev. 2010;74:417-33.
    • (2010) Microbiol Mol Biol Rev , vol.74 , pp. 417-433
    • Davies, J.1    Davies, D.2
  • 72
    • 84942601773 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention. Available online: Published 2013. Accessed on January 12
    • Threat Report 2013: Antibiotic/Antimicrobial Resistance. Centers for Disease Control and Prevention. Available online: http://www.cdc.gov/drugresistance/threat-report-2013/. Published 2013. Accessed on January 12, 2015
    • (2015) Threat Report 2013: Antibiotic/Antimicrobial Resistance.
  • 73
    • 77957708554 scopus 로고    scopus 로고
    • Complicated urinary tract infections: practical solutions for the treatment of multiresistant Gram-negative bacteria
    • iii25-33
    • Pallett A, Hand K. Complicated urinary tract infections: practical solutions for the treatment of multiresistant Gram-negative bacteria. J Antimicrob Chemother. 2010;65 Suppl 3:iii25-33.
    • (2010) J Antimicrob Chemother , vol.65
    • Pallett, A.1    Hand, K.2
  • 74
    • 79952199427 scopus 로고    scopus 로고
    • Management of complicated urinary tract infections in the era of antimicrobial resistance
    • Bader MS, Hawboldt J, Brooks A. Management of complicated urinary tract infections in the era of antimicrobial resistance. Postgrad Med. 2010;122:7-15.
    • (2010) Postgrad Med , vol.122 , pp. 7-15
    • Bader, M.S.1    Hawboldt, J.2    Brooks, A.3
  • 75
    • 84926343938 scopus 로고    scopus 로고
    • Multi-drug resistance, inappropriate initial antibiotic therapy and mortality in Gram-negative severe sepsis and septic shock: a retrospective cohort study
    • Zilberberg MD, Shorr AF, Micek ST, Vazquez-Guillamet C, Kollef MH. Multi-drug resistance, inappropriate initial antibiotic therapy and mortality in Gram-negative severe sepsis and septic shock: a retrospective cohort study. Crit Care. 2014;18:596.
    • (2014) Crit Care , vol.18 , pp. 596
    • Zilberberg, M.D.1    Shorr, A.F.2    Micek, S.T.3    Vazquez-Guillamet, C.4    Kollef, M.H.5
  • 76
    • 84942578246 scopus 로고    scopus 로고
    • Available online: Published on 2009. Accessed on January 12
    • The bacterial challenge: time to react. Available online: http://ecdc.europa.eu/en/publications/Publications/0909_TER_The_Bacterial_Challenge_Time_to_React.pdf. Published on 2009. Accessed on January 12, 2015
    • (2015) The bacterial challenge: time to react.
  • 77
    • 84895779263 scopus 로고    scopus 로고
    • Addressing the emergence and impact of multidrug-resistant gram-negative organisms: a critical focus for the next decade
    • Lautenbach E, Perencevich EN. Addressing the emergence and impact of multidrug-resistant gram-negative organisms: a critical focus for the next decade. Infect Control Hosp Epidemiol. 2014;35:333-5.
    • (2014) Infect Control Hosp Epidemiol , vol.35 , pp. 333-335
    • Lautenbach, E.1    Perencevich, E.N.2


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