High-throughput sequencing reveals an altered T cell repertoire in X-linked agammaglobulinemia

Clinical Immunology

Volumn 161, Issue 2, 2015, Pages 190-196

  Ramesh, Manish ^a   Simchoni, Noa ^b   Hamm, David ^c   Cunningham Rundles, Charlotte ^b  

^a MONTEFIORE MEDICAL CENTER   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c ADAPTIVE BIOTECHNOLOGIES   (United States)

Author keywords

Amino acid sequence; High throughput sequencing; Junctional diversity; T cell receptor; XLA

Indexed keywords

T LYMPHOCYTE RECEPTOR; DNA; IMMUNOGLOBULIN VARIABLE REGION; LYMPHOCYTE ANTIGEN RECEPTOR;

ADULT; AMINO ACID SEQUENCE; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; GENE DELETION; GENE INSERTION; GENETIC VARIABILITY; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; T LYMPHOCYTE; VDJ RECOMBINATION; X LINKED AGAMMAGLOBULINEMIA; ADOLESCENT; AGAMMAGLOBULINEMIA; B LYMPHOCYTE; CASE CONTROL STUDY; GENETICS; IMMUNOGLOBULIN VARIABLE REGION; INFANT; METABOLISM; MIDDLE AGED; PRESCHOOL CHILD; PROCEDURES; X CHROMOSOME LINKED DISORDER; YOUNG ADULT;

ADOLESCENT; ADULT; AGAMMAGLOBULINEMIA; B-LYMPHOCYTES; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; DNA; GENETIC DISEASES, X-LINKED; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; INFANT; MALE; MIDDLE AGED; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES; YOUNG ADULT;

EID: 84942575118     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2015.09.002     Document Type: Article

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