Prevalence and antibiotic susceptibility of bacteria from acute and chronic wounds in Malaysian subjects

Journal of Infection in Developing Countries

Volumn 9, Issue 9, 2015, Pages 936-944

  Wong, Shin Yee ^a   Manikam, Rishya ^a   Muniandy, Sekaran ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

Antibiotic resistance; Microbiota; Wound

Indexed keywords

AMPICILLIN; AZTREONAM; CEFALOTIN; CEFAZOLIN; CEFUROXIME; CHLORAMPHENICOL; CIPROFLOXACIN; DALFOPRISTIN PLUS QUINUPRISTIN; DAPTOMYCIN; LEVOFLOXACIN; LINEZOLID; PENICILLIN DERIVATIVE; PIPERACILLIN PLUS TAZOBACTAM; SULTAMICILLIN; TETRACYCLINE; TIGECYCLINE; ANTIINFECTIVE AGENT;

ADULT; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM CULTURE; CHRONIC WOUND; CONTROLLED STUDY; FEMALE; FISHER EXACT TEST; HUMAN; MAJOR CLINICAL STUDY; MALAYSIA; MALE; MICROFLORA; PROTEUS MIRABILIS; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STAPHYLOCOCCUS HAEMOLYTICUS; WOUND HEALING; AGED; BACTERIUM; CLASSIFICATION; DRUG EFFECTS; INJURY; ISOLATION AND PURIFICATION; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MIDDLE AGED; PREVALENCE; PROSPECTIVE STUDY; VERY ELDERLY; WOUND INFECTION;

ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BACTERIA; BACTERIOLOGICAL TECHNIQUES; FEMALE; HUMANS; MALAYSIA; MALE; MIDDLE AGED; PREVALENCE; PROSPECTIVE STUDIES; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; WOUND INFECTION; WOUNDS AND INJURIES;

EID: 84942543869     PISSN: 20366590     EISSN: 19722680     Source Type: Journal    
DOI: 10.3855/jidc.5882     Document Type: Article

References (54)

1. Pruitt Jr BA, McManus AT, Kim SH, Goodwin CW (1998) Burn wound infections: current status. World J Surg 22: 135-145.
2. Segre JA (2006) Epidermal barrier formation and recovery in skin disorders. J Clin Invest 116: 1150-1158.
3. Bowler PG, Duerden BI, Armstrong DG (2001) Wound microbiology and associated approaches to wound management. Clin Microbiol Rev 14: 244-269.
4. Epstein FH, Singer AJ, Clark RA (1999) Cutaneous wound healing. N Eng J Med 341: 738-746.
5. Chaby G, Senet P, Vaneau M, Martel P, Guillaume JC, Meaume S, Teot L, Debure C, Dompmartin A, Bachelet H, Carsin H, Matz V, Richard JL, Rochet JM, Sales-Aussias N, Zaqnoli A, Dennis C, Guillot B, Chosidow O (2007) Dressings for acute and chronic wounds: a systematic review. Arch Dermatol 143: 1297-1304.
6. Wolcott RD, Rhoads DD, Dowd SE (2008) Biofilms and chronic wound inflammation. J Wound Care 17: 333-341.
7. Moreo K (2005) Understanding and overcoming the challenges of effective case management for patients with chronic wounds. Case Manager 30: 145-151.
8. Hareendran A, Bradburry A, Budd J, Geroulakos G, Hobbs R, Kenkre J, Symonds T (2005) Measuring the impact of venous leg ulcers on quality of life. J Wound Care 14: 53-57.
9. Eming SA, Krieg T, Davidson JM (2007) Inflammation in wound repair: molecular and cellular mechanisms. J Invest Dermatol 127: 514-525.
10. Loots MA, Lamme EN, Zeegelaar J, Mekkes JR, Bos JD, Middelkoop E (1998) Differences in cellular infiltrate and extracellular matrix of chronic diabetic and venous ulcers versus acute wounds. J Invest Dermatol 111: 850-857.
11. Falanga V (2004) The chronic wound: impaired healing and solutions in the context of wound bed preparation. Blood Cells Mol Dis 32: 88-94.
12. Davies CE, Wilson MJ, Hill KE, Stephens P, Hill CM, Harding KG, Thomas DW (2001) Use of molecular techniques to study microbial diversity in the skin: chronic wounds reevaluated. Wound Repair Regen 9: 332-340.
13. Bowler PG, Davies BJ (1999) The microbiology of infected and noninfected leg ulcers. Int J Dermatol 38: 573-578.
14. Davies CE, Hill KE, Wilson MJ, Stephens P, Hill CM, Harding KG, Thomas DW (2004) Use of 16S Ribosomal DNA PCR and denaturing gradient gel electrophoresis for analysis of the microfloras of healing and nonhealing chronic venous leg ulcers. J Clin Microbiol 42: 3549-3557.
15. Dowd SE, Wolcott RD, Sun Y, McKeehan T, Smith E, Rhoads D (2008) Polymicrobial nature of chronic diabetic foot ulcer biofilm infections determined using bacterial tag encoded FLX amplicon pyrosequencing (bTEFAP). PLoS One 3: e3326.
16. Sader HS, Jones RN, Silva JB (2002) Skin and soft tissue infections in Latin American medical centers: four-year assessment of the pathogen frequency and antimicrobial susceptibility patterns. Diagn Microbiol Infect Dis 44: 281-288.
17. Mosel M, Li L, Drlica K, Zhao X (2013) Superoxidemediated protection of Escherichia coli from antimicrobials. Antimicrob Agents Chemother 57: 5755-5759.
18. Okeke IN, Laxminarayan R, Bhutta ZA, Duse AG, Jenkins P, O'Brien TF, Pablos-Mendez A, Klugman KP (2005) Antimicrobial resistance in developing countries. Part I: recent trends and current status. Lancet Infect Dis 5: 481-493.
19. Hartemann-Heurtier A, Robert J, Jacqueminet S, HaVan G, Golmard J, Jarlier V, Grimaldi A (2004) Diabetic foot ulcer and multidrug-resistant organisms: risk factors and impact. Diabetic Med 21: 710-715.
20. Clinical and Laboratory Standards Institute (2013) Performance standards for antimicrobial susceptibility testing: 23rd informational supplement (M100-S23). Wayne: CLSI.
21. Stadelmann WK, Digenis AG, Tobin GR (1998) Physiology and healing dynamics of chronic cutaneous wounds. Am J Surg 176: 26-38.
22. Lazarus GS, Cooper DM, Knighton DR, Margolis DJ, Percoraro RE, Rodeheaver G, Robson MC (1994) Definitions and guidelines for assessment of wounds and evaluation of healing. Wound Repair Regen 2: 165-170.
23. Monaco JL, Lawrence WT (2003) Acute wound healing: an overview. Clin Plast Surg 30: 1-12.
24. Gurtner GC, Werner S, Barrandon Y, Longaker MT (2008) Wound repair and regeneration. Nature 453: 314-321.
25. Drinkwater S, Smith A, Burnand K (2002) What can wound fluids tell us about the venous ulcer microenvironment? Int J Low Extrem Wounds 1: 184-190.
26. Baker S, Stacey M, Jopp-McKay A, Hoskin S, Thompson P (1991) Epidemiology of chronic venous ulcers. Br J Surg 78: 864-867.
27. Dale J, Callam M, Ruckley C, Harper D, Berrey P (1983) Chronic ulcers of the leg: a study of prevalence in a Scottish community. Health Bulletin 41: 310.
28. Nelzen O, Bergqvist D, Lindhagen A, Hallböök T (1991) Chronic leg ulcers: an underestimated problem in primary health care among elderly patients. J Epidemiol Community Health 45: 184-187.
29. Guo S, DiPietro LA (2010) Factors Affecting Wound Healing. J Dent Res 89: 219-229.
30. James GA, Swogger E, Wolcott R, Secor P, Sestrich J, Costerton JW, Stewart PS (2008) Biofilms in chronic wounds. Wound Repair Regen 16: 37-44.
31. Gjodsbol K, Christensen JJ, Karlsmark T, Jorgensen B, Klein BM, Krogfelt KA (2006) Multiple bacterial species reside in chronic wounds: a longitudinal study. Int Wound J 3: 225-231.
32. Madsen SM, Westh H, Danielsen L, Rosdahl VT (1996) Bacterial colonization and healing of venous leg ulcers. APMIS 104: 895-899.
33. Zhao G, Hochwalt PC, Usui ML, Underwood RA, Singh PK, James GA, Stewart PS, Fleckman P, Olerud JE (2010) Delayed wound healing in diabetic (db/db) mice with Pseudomonas aeruginosa biofilm challenge: a model for the study of chronic wounds. Wound Repair Regen 18: 467-477.
34. Athanasopoulos AN, Economopoulou M, Orlova VV, Sobke A, Schneider D, Weber H, Augustin HG, Eming SA, Schubert U, Linn T, Nawroth PP, Hussain M, Hammes HP, Herrmann M, Preissner KT, Chavakis T (2006) The extracellular adherence protein (Eap) of Staphylococcus aureus inhibits wound healing by interfering with host defense and repair mechanisms. Blood 107: 2720-2727.
35. Edwards AM, Bowden MG, Brown EL, Laabei M, Massey RC (2012) Staphylococcus aureus extracellular adherence protein triggers TNFalpha release, promoting attachment to endothelial cells via protein A. PLoS One 7: e43046.
36. Bjarnsholt T, Kirketerp-Møller K, Jensen PØ, Madsen KG, Phipps R, Krogfelt K, Høiby N, Givskov M (2008) Why chronic wounds will not heal: a novel hypothesis. Wound Repair Regen 16: 2-10.
37. El-Din AB, El-Nadgy M, Badr R, El-Sabagh A (2008) Pseudomonas aeruginosa exotoxin A: its role in burn wound infection and wound healing. Egypt J Plast Reconstr Surg 32: 59-65.
38. Gurjala AN, Geringer MR, Seth AK, Hong SJ, Smeltzer MS, Galiano RD, Leong KP, Mustoe TA (2011) Development of a novel, highly quantitative in vivo model for the study of biofilm‐impaired cutaneous wound healing. Wound Repair Regen 19: 400-410.
39. Seth AK, Geringer MR, Galiano RD, Leung KP, Mustoe TA, Hong SJ (2012) Quantitative comparison and analysis of species-specific wound biofilm virulence using an in vivo, rabbit-ear model. J Am Coll Surg 215: 388-399.
40. Zhao G, Usui ML, Underwood RA, Singh PK, James GA, Stewart PS, Fleckman P, Olerud JE (2012) Time course study of delayed wound healing in a biofilm‐challenged diabetic mouse model. Wound Repair Regen 20: 342-352.
41. Donlan RM, Costerton JW (2002) Biofilms: survival mechanisms of clinically relevant microorganisms. Clin Microbiol Rev 15: 167-193.
42. Kirby WMM (1944) Extraction of a highly potent penicillin inactivator from penicillin resistant staphylococcal. Science 99: 452-453.
43. Jessen O, Rosendal K, Bülow P, Faber V, Eriksen KR (1969) Changing staphylococci and staphylococcal infections: A tenyear study of bacteria and cases of bacteremia. N Eng J Med 281: 627-635.
44. Goldstein EJ, Citron DM, Nesbit CA (1996) Diabetic foot infections: bacteriology and activity of 10 oral antimicrobial agents against bacteria isolated from consecutive cases. Diabetes Care 19: 638-641.
45. Tentolouris N, Jude E, Smirnof I, Knowles E, Boulton A (1999) Methicillin-resistant Staphylococcus aureus: an increasing problem in a diabetic foot clinic. Diabetic Med 16: 767-771.
46. Jean SS, Hsueh PR (2011) High burden of antimicrobial resistance in Asia. Int J Antimicrob Agents 37: 291-295.
47. Paterson DL (2006) The epidemiological profile of infections with multidrug resistant Pseudomonas aeruginosa and Acinetobacter species. Clinical Infect Dis 43 Suppl 2: S43-S48.
48. Tammelin A, Lindholm C, Hambraeus A (1998) Chronic ulcers and antibiotic treatment. J Wound Care 7: 435-437.
49. Alivoni A, Bassissi P, Pini M (1986) Systemic administration of antibiotics in the management of venous ulcer: A randomized clinical trial. J Am Acad Dermatol 2: 186-191.
50. O'Meara S, Al-Kurdi D, Olugun Y, Ovington L, Martyn-St James M, Richardson R (2013) Antibiotics and antiseptics for venous leg ulcers. Cochrane Database Syst Rev 1: CD003557.
51. Howell-Jones RS, Wilson MJ, Hill KE, Howard AJ, Price PE, Thomas DW (2005) A review of the microbiology, antibiotic usage and resistance in chronic skin wounds. J Antimicrob Chemother 55: 143-149.
52. Drancourt M, Bollet C, Carlioz A, Martelin R, Gayral JP, Raoult D (2000) 16S ribosomal DNA sequence analysis of a large collection of environmental and clinical unidentifiable bacterial isolates. J Clin Microbiol 38: 3623-3630.
53. Liu Y, Liu X, Qu Y, Wang X, Li L, Zhao X (2012) Inhibitors of reactive oxygen species accumulation delay and/or reduce the lethality of several antistaphylococcal agents. Antimicrob Agents Chemother 56: 6048-6050.
54. Landis SJ (2008) Chronic wound infection and antimicrobial use. Adv Skin Wound Care 21: 531-540.