Staphylococcus aureus extracellular adherence protein triggers TNFα release, promoting attachment to endothelial cells via protein A

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Edwards, Andrew M ^a,d   Bowden, Maria Gabriela ^b,e   Brown, Eric L ^c   Laabei, Maisem ^a   Massey, Ruth C ^a  

^a University of Bath   (United Kingdom)

^b UNIVERSITY OF TEXAS   (United States)

^c UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF HOUSTON DOWNTOWN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; EXTRACELLULAR ADHERENCE PROTEIN; PROTEIN P33; STAPHYLOCOCCUS PROTEIN A; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTEREMIA; BACTERIAL CHROMOSOME; BACTERIAL GENE; BACTERIUM ADHERENCE; CELL SURFACE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE SEVERITY; DOSE TIME EFFECT RELATION; ENDOTHELIUM CELL; EXTRACELLULAR ADHERENCE PROTEIN GENE; FIBRONECTIN BINDING PROTEIN A GENE; GEH GENE; GENE INACTIVATION; GENE INSERTION; GENE MUTATION; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PURIFICATION; STAPHYLOCOCCUS AUREUS; UPREGULATION; WEIGHT REDUCTION;

ADHESINS, BACTERIAL; ANIMALS; BACTERIAL ADHESION; BACTERIAL PROTEINS; CHROMOSOMES, BACTERIAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCARDITIS; GENE EXPRESSION REGULATION, BACTERIAL; GENETIC COMPLEMENTATION TEST; HUMANS; INFLAMMATION; MICE; OSTEOMYELITIS; RNA-BINDING PROTEINS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCAL PROTEIN A; STAPHYLOCOCCUS AUREUS; STEM CELLS; TUMOR NECROSIS FACTOR-ALPHA; VIRULENCE FACTORS;

EID: 84865050224     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043046     Document Type: Article

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