SYK expression endows human ZAP70-deficient CD8 T cells with residual TCR signaling

Clinical Immunology

Volumn 161, Issue 2, 2015, Pages 103-109

  Hauck, Fabian ^a,b   Blumenthal, Britta ^d,e   Fuchs, Sebastian ^d,e   Lenoir, Christelle ^b   Martin, Emmanuel ^b   Speckmann, Carsten ^e   Vraetz, Thomas ^e   Mannhardt Laakmann, Wilma ^f   Lambert, Nathalie ^g   Gil, Marine ^g   Borte, Stephan ^h,i   Audrain, Marie ^j   Schwarz, Klaus ^k   Lim, Annick ^l   Schamel, Wolfgang W ^d,e   Fischer, Alain ^b,c,g,m   Ehl, Stephan ^e   Rensing Ehl, Anne ^e   Picard, Capucine ^b,c,g   Latour, Sylvain ^b,c  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b IMAGINE INSTITUTE   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d UNIVERSITY OF FREIBURG   (Germany)

^e UNIVERSITY OF FREIBURG   (Germany)

^f UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^g HÔPITAL NECKER ENFANTS MALADES   (France)

^h Klinikum St Georg   (Germany)

ⁱ UNIVERSITY OF LEIPZIG   (Germany)

^j NANTES UNIVERSITY HOSPITAL   (France)

^k German Red Cross Blood Transfusion Service Baden Württemberg Hessen and University Hospital Ulm   (Germany)

^l INSTITUT PASTEUR   (France)

^m Centre de Recherche Interdisciplinaire en Biologie   (France)

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Author keywords

CID; Live vaccine adverse event; SYK; TCR signaling; TREC newborn screening; ZAP70

Indexed keywords

ACETAZOLAMIDE; ACICLOVIR; CALCIUM ION; IMMUNOGLOBULIN; IMMUNOSUPPRESSIVE AGENT; LIVE VACCINE; MEASLES MUMPS RUBELLA VACCINE; PENICILLIN V; PROTEIN KINASE SYK; PROTEIN KINASE ZAP 70; RAPAMYCIN; STEROID; VARICELLA ZOSTER VACCINE; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE; ZAP70 PROTEIN, HUMAN;

ACINETOBACTER BAUMANNII; ADULT RESPIRATORY DISTRESS SYNDROME; ANTIBIOTIC PROPHYLAXIS; APOPTOSIS; ARTICLE; ARTIFICIAL VENTILATION; BRONCHIOLITIS; BRONCHITIS; CALCIUM TRANSPORT; CASE REPORT; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHILD; COMBINED IMMUNODEFICIENCY; DEGRANULATION; DERMATITIS; FAILURE TO THRIVE; GASTROENTERITIS; GENETIC ANALYSIS; GENOTYPE; GRAFT VERSUS HOST REACTION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HERPES ZOSTER; HERPES ZOSTER ENCEPHALITIS; HETEROZYGOTE; HUMAN; HUMAN CELL; HUMAN RESPIRATORY SYNCYTIAL VIRUS; INFANT; INFECTION; INFECTION SENSITIVITY; INJECTION SITE RASH; INTRACELLULAR SIGNALING; INTRACRANIAL HYPERTENSION; LOW DRUG DOSE; LUNG INFECTION; MALE; MISSENSE MUTATION; MOLECULAR GENETICS; MYCOSIS; NEWBORN; NEWBORN SCREENING; NONSENSE MUTATION; ONSET AGE; OPPORTUNISTIC INFECTION; PERICARDITIS; PHENOTYPE; PNEUMONIA; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECURRENT INFECTION; REDUCED INTENSITY CONDITIONING; ROTAVIRUS; SEPSIS; STAPHYLOCOCCUS AUREUS; STENOTROPHOMONAS MALTOPHILIA; SUPERINFECTION; THRUSH; DEFICIENCY; IMMUNE DEFICIENCY; IMMUNOLOGY; MUTATION; RETROSPECTIVE STUDY; SEVERE COMBINED IMMUNODEFICIENCY; SIGNAL TRANSDUCTION;

CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHILD, PRESCHOOL; HUMANS; IMMUNOLOGIC DEFICIENCY SYNDROMES; INFANT; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MUTATION; PROTEIN-TYROSINE KINASES; RECEPTORS, ANTIGEN, T-CELL; RETROSPECTIVE STUDIES; SEVERE COMBINED IMMUNODEFICIENCY; SIGNAL TRANSDUCTION; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 84942526194     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2015.07.002     Document Type: Article

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