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Volumn 12, Issue 1, 2015, Pages

Adult autologous mesenchymal stem cells for the treatment of suspected non-infectious inflammatory diseases of the canine central nervous system: Safety, feasibility and preliminary clinical findings

Author keywords

Central nervous system; Dog; Meningoencephalitis; Mesenchymal stem cells

Indexed keywords

CYTARABINE; ETIRACETAM; PHENOBARBITAL; PREDNISOLONE; PREDNISONE; ANTIINFLAMMATORY AGENT;

EID: 84942512763     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0402-9     Document Type: Article
Times cited : (31)

References (51)
  • 1
    • 84908547850 scopus 로고    scopus 로고
    • Perspectives on meningoencephalomyelitis of unknown origin
    • Coates JR, Jeffery ND: Perspectives on meningoencephalomyelitis of unknown origin. Vet Clin Small Anim. 2014;44 (6):1157-1185.
    • (2014) Vet Clin Small Anim , vol.44 , Issue.6 , pp. 1157-1185
    • Coates, J.R.1    Jeffery, N.D.2
  • 2
    • 77950616104 scopus 로고    scopus 로고
    • Idiopathic granulomatous and necrotising inflammatory disorders of the canine central nervous system: a review and future perspectives
    • Talarico LR, Schatzberg SJ. Idiopathic granulomatous and necrotising inflammatory disorders of the canine central nervous system: a review and future perspectives. J Small Anim Pract. 2010;51:138-49.
    • (2010) J Small Anim Pract , vol.51 , pp. 138-149
    • Talarico, L.R.1    Schatzberg, S.J.2
  • 4
    • 0025929446 scopus 로고
    • Myocardial necrosis in a pug dog with necrotizing meningoencephalitis
    • Bradley GA. Myocardial necrosis in a pug dog with necrotizing meningoencephalitis. Vet Pathol. 1991;28:91-3.
    • (1991) Vet Pathol. , vol.28 , pp. 91-93
    • Bradley, G.A.1
  • 5
    • 0024662020 scopus 로고
    • A necrotizing meningoencephalitis of pug dogs
    • Cordy DR, Holliday TA. A necrotizing meningoencephalitis of pug dogs. Vet Pathol. 1989;26:191-4.
    • (1989) Vet Pathol. , vol.26 , pp. 191-194
    • Cordy, D.R.1    Holliday, T.A.2
  • 6
    • 7744231464 scopus 로고    scopus 로고
    • Cervical hyperaesthesia in a Maltese terrier with necrotising meningoencephalitis
    • Fearnside SM, Kessell AE, Powe JR. Cervical hyperaesthesia in a Maltese terrier with necrotising meningoencephalitis. Aust Vet J. 2004;82:550-2.
    • (2004) Aust Vet J , vol.82 , pp. 550-552
    • Fearnside, S.M.1    Kessell, A.E.2    Powe, J.R.3
  • 7
    • 84985396253 scopus 로고
    • Magnetic resonance imaging in two dogs with central nervous system disease
    • Panciera DL, Duncan ID, Messing A. Magnetic resonance imaging in two dogs with central nervous system disease. J Small Anim Pract. 1987;28:587-96.
    • (1987) J Small Anim Pract , vol.28 , pp. 587-596
    • Panciera, D.L.1    Duncan, I.D.2    Messing, A.3
  • 8
    • 1542469358 scopus 로고    scopus 로고
    • A comparative pathological study on canine necrotizing meningoencephalitis and granulomatous meningoencephalomyelitis
    • Suzuki M, Uchida K, Morozumi M, Hasegawa T, Yanai T, Nakayama H, et al. A comparative pathological study on canine necrotizing meningoencephalitis and granulomatous meningoencephalomyelitis. J Vet Med Sci. 2003;65:1233-9.
    • (2003) J Vet Med Sci , vol.65 , pp. 1233-1239
    • Suzuki, M.1    Uchida, K.2    Morozumi, M.3    Hasegawa, T.4    Yanai, T.5    Nakayama, H.6    Tateyama, S.7
  • 10
    • 0035234375 scopus 로고    scopus 로고
    • Necrotizing meningoencephalitis associated with cortical hippocampal hamartia in a Pekingese dog
    • Cantile C, Chianini F, Arispici M, Fatzer R. Necrotizing meningoencephalitis associated with cortical hippocampal hamartia in a Pekingese dog. Vet Pathol. 2001;38:119-22.
    • (2001) Vet Pathol , vol.38 , pp. 119-122
    • Cantile, C.1    Chianini, F.2    Arispici, M.3    Fatzer, R.4
  • 11
    • 70449521221 scopus 로고    scopus 로고
    • Leigh-like subacute necrotising encephalopathy in Yorkshire terriers: neuropathological characterisation, respiratory chain activities and mitochondrial DNA
    • Baiker K, Hofmann S, Fischer A, Gödde T, Medl S, Schmahl W, et al. Leigh-like subacute necrotising encephalopathy in Yorkshire terriers: neuropathological characterisation, respiratory chain activities and mitochondrial DNA. Acta Neuropathol. 2009;118:697-709.
    • (2009) Acta Neuropathol , vol.118 , pp. 697-709
    • Baiker, K.1    Hofmann, S.2    Fischer, A.3    Gödde, T.4    Medl, S.5    Schmahl, W.6    Bauer, M.F.7    Matiasek, K.8
  • 13
    • 77649274092 scopus 로고    scopus 로고
    • Immunohistochemical characterization of inflammatory and glial responses in a case of necrotizing leukoencephalitis in a French bulldog
    • Spitzbarth I, Schenk HC, Tipold A, Beineke A. Immunohistochemical characterization of inflammatory and glial responses in a case of necrotizing leukoencephalitis in a French bulldog. J Comp Pathol. 2010;142:235-41.
    • (2010) J Comp Pathol , vol.142 , pp. 235-241
    • Spitzbarth, I.1    Schenk, H.C.2    Tipold, A.3    Beineke, A.4
  • 14
    • 77952550276 scopus 로고    scopus 로고
    • Clinical findings and treatment of non-infectious meningoencephalomyelitis in dogs: a systematic review of 457 published cases from 1962 to 2008
    • Granger N, Smith PM, Jeffery ND. Clinical findings and treatment of non-infectious meningoencephalomyelitis in dogs: a systematic review of 457 published cases from 1962 to 2008. Vet J. 2010;184:290-7.
    • (2010) Vet J , vol.184 , pp. 290-297
    • Granger, N.1    Smith, P.M.2    Jeffery, N.D.3
  • 15
    • 0031606613 scopus 로고    scopus 로고
    • Immunohistochemical characterization of inflammatory cells in brains of dogs with granulomatous meningoencephalitis
    • Kipar A, Baumgartner W, Vogl C, Gaedke K, Wellman M. Immunohistochemical characterization of inflammatory cells in brains of dogs with granulomatous meningoencephalitis. Vet Pathol. 1998;35:43-52.
    • (1998) Vet Pathol , vol.35 , pp. 43-52
    • Kipar, A.1    Baumgartner, W.2    Vogl, C.3    Gaedke, K.4    Wellman, M.5
  • 16
    • 84985325695 scopus 로고
    • Granulomatous meningoencephalomyelitis in 21 dogs
    • Thomas JB, Eger C. Granulomatous meningoencephalomyelitis in 21 dogs. J Small Anim Pract. 1989;30:287-93.
    • (1989) J Small Anim Pract , vol.30 , pp. 287-293
    • Thomas, J.B.1    Eger, C.2
  • 19
    • 0035400122 scopus 로고    scopus 로고
    • Neuronal survival after CNS insult is determined by a genetically encoded autoimmune response
    • Kipnis J, Yoles E, Schori H, Hauben E, Shaked I, Schwartz M. Neuronal survival after CNS insult is determined by a genetically encoded autoimmune response. J Neurosci. 2001;21:4564-71.
    • (2001) J Neurosci , vol.21 , pp. 4564-4571
    • Kipnis, J.1    Yoles, E.2    Schori, H.3    Hauben, E.4    Shaked, I.5    Schwartz, M.6
  • 20
    • 77956344034 scopus 로고    scopus 로고
    • Looking at the blood-brain barrier: molecular anatomy and possible investigation approaches
    • Cardoso R, Brites D, Brito MA. Looking at the blood-brain barrier: molecular anatomy and possible investigation approaches. Brain Res Rev. 2010;64:328-64.
    • (2010) Brain Res Rev , vol.64 , pp. 328-364
    • Cardoso, R.1    Brites, D.2    Brito, M.A.3
  • 23
    • 41449102630 scopus 로고    scopus 로고
    • Treatment of 11 dogs with meningoencephalomyelitis of unknown origin with a combination of prednisolone and cytosine arabinoside
    • Menaut P, Landart J, Behr S, Lanore D, Trumel C. Treatment of 11 dogs with meningoencephalomyelitis of unknown origin with a combination of prednisolone and cytosine arabinoside. Vet Rec. 2008;162:241-5.
    • (2008) Vet Rec , vol.162 , pp. 241-245
    • Menaut, P.1    Landart, J.2    Behr, S.3    Lanore, D.4    Trumel, C.5
  • 24
    • 65849291460 scopus 로고    scopus 로고
    • Chimerization of astroglial population in the lumbar spinal cord after mesenchymal stem cell transplantation prolongs survival in a rat model of amyotrophic lateral sclerosis
    • Boucherie C, Schafer S, Lavand'homme P, Maloteaux JM, Hermans E. Chimerization of astroglial population in the lumbar spinal cord after mesenchymal stem cell transplantation prolongs survival in a rat model of amyotrophic lateral sclerosis. J Neurosci Res. 2009;87:2034-46.
    • (2009) J Neurosci Res , vol.87 , pp. 2034-2046
    • Boucherie, C.1    Schafer, S.2    Lavand'homme, P.3    Maloteaux, J.M.4    Hermans, E.5
  • 25
    • 71749083461 scopus 로고    scopus 로고
    • Mesenchymal stem cell transplantation attenuates blood brain barrier damage and neuroinflammation and protects dopaminergic neurons against MPTP toxicity in the substantia nigra in a model of Parkinson's disease
    • Chao YX, He BP, Tay SS. Mesenchymal stem cell transplantation attenuates blood brain barrier damage and neuroinflammation and protects dopaminergic neurons against MPTP toxicity in the substantia nigra in a model of Parkinson's disease. J Neuroimmunol. 2009;216:39-50.
    • (2009) J Neuroimmunol , vol.216 , pp. 39-50
    • Chao, Y.X.1    He, B.P.2    Tay, S.S.3
  • 27
    • 79956227192 scopus 로고    scopus 로고
    • Mesenchymal stem cells in a transgenic mouse model of multiple system atrophy: immunomodulation and neuroprotection
    • Stemberger S, Jamnig A, Stefanova N, Lepperdinger G, Reindl M, Wenning GK. Mesenchymal stem cells in a transgenic mouse model of multiple system atrophy: immunomodulation and neuroprotection. PLoS One. 2011;6(5):e19808.
    • (2011) PLoS One , vol.6 , Issue.5 , pp. e19808
    • Stemberger, S.1    Jamnig, A.2    Stefanova, N.3    Lepperdinger, G.4    Reindl, M.5    Wenning, G.K.6
  • 28
    • 33746424373 scopus 로고    scopus 로고
    • Mesenchymal stem cells as trophic mediators
    • Caplan AI, Dennis JE. Mesenchymal stem cells as trophic mediators. J Cell Biochem. 2006;98:1076-84.
    • (2006) J Cell Biochem , vol.98 , pp. 1076-1084
    • Caplan, A.I.1    Dennis, J.E.2
  • 29
    • 79959951133 scopus 로고    scopus 로고
    • The MSC: an injury drugstore
    • Caplan AI, Correa D. The MSC: an injury drugstore. Cell Stem Cell. 2011;9:11-5.
    • (2011) Cell Stem Cell , vol.9 , pp. 11-15
    • Caplan, A.I.1    Correa, D.2
  • 31
    • 34648860537 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stromal cells for the repair of central nervous system injury
    • Parr AM, Tator CH, Keating A. Bone marrow-derived mesenchymal stromal cells for the repair of central nervous system injury. Bone Marrow Transplant. 2007;40:609-19.
    • (2007) Bone Marrow Transplant , vol.40 , pp. 609-619
    • Parr, A.M.1    Tator, C.H.2    Keating, A.3
  • 32
    • 67349288557 scopus 로고    scopus 로고
    • Effects of human marrow stromal cells on activation of microglial cells and production of inflammatory factors induced by lipopolysaccharide
    • Zhou C, Zhang C, Chi S, Xu Y, Teng J, Wang H, et al. Effects of human marrow stromal cells on activation of microglial cells and production of inflammatory factors induced by lipopolysaccharide. Brain Res. 2009;1269:23-30.
    • (2009) Brain Res , vol.1269 , pp. 23-30
    • Zhou, C.1    Zhang, C.2    Chi, S.3    Xu, Y.4    Teng, J.5    Wang, H.6    Song, Y.7    Zhao, R.8
  • 33
    • 70349159499 scopus 로고    scopus 로고
    • Multipotent mesenchymal stromal cells attenuate chronic inflammation and injury-induced sensitivity to mechanical stimuli in experimental spinal cord injury
    • Abrams MB, Dominguez C, Pernold K, Reger R, Wiesenfeld-Hallin Z, Olson L, et al. Multipotent mesenchymal stromal cells attenuate chronic inflammation and injury-induced sensitivity to mechanical stimuli in experimental spinal cord injury. Restor Neurol Neurosci. 2009;27:307-21.
    • (2009) Restor Neurol Neurosci , vol.27 , pp. 307-321
    • Abrams, M.B.1    Dominguez, C.2    Pernold, K.3    Reger, R.4    Wiesenfeld-Hallin, Z.5    Olson, L.6    Prockop, D.7
  • 34
    • 34247109495 scopus 로고    scopus 로고
    • Bone marrow stromal cells induce changes in pain behavior after sciatic nerve constriction
    • Musolino PL, Coronel MF, Hokfelt T, Villar MJ. Bone marrow stromal cells induce changes in pain behavior after sciatic nerve constriction. Neurosci Lett. 2007;418:97-101.
    • (2007) Neurosci Lett , vol.418 , pp. 97-101
    • Musolino, P.L.1    Coronel, M.F.2    Hokfelt, T.3    Villar, M.J.4
  • 36
    • 84942540821 scopus 로고    scopus 로고
    • Linee guida concernenti i requisiti sanitari minimi per l'impiego delle cellule staminali in medicina veterinaria
    • 147/CSR del 17 ottobre
    • Linee guida concernenti i requisiti sanitari minimi per l'impiego delle cellule staminali in medicina veterinaria. Rep Atti n. 147/CSR del 17 ottobre 2013
    • (2013) Rep Atti n
  • 37
    • 0001316645 scopus 로고
    • Surgical preparation of externalized carotid artery loops in dogs
    • Brown ML, Korol B. Surgical preparation of externalized carotid artery loops in dogs. Physiol Behav. 1968;3(1):207-8.
    • (1968) Physiol Behav , vol.3 , Issue.1 , pp. 207-208
    • Brown, M.L.1    Korol, B.2
  • 39
    • 0036779688 scopus 로고    scopus 로고
    • Unravelling the pathogenesis of myasthenia gravis
    • Vincent A. Unravelling the pathogenesis of myasthenia gravis. Nat Rev Immunol. 2002;2:797-804.
    • (2002) Nat Rev Immunol , vol.2 , pp. 797-804
    • Vincent, A.1
  • 45
    • 84860915471 scopus 로고    scopus 로고
    • The role of pro- and anti-inflammatory cytokines in the pathogenesis of spontaneous canine diseases
    • Spitzbarth I, Baumgartner W, Beineke A. The role of pro- and anti-inflammatory cytokines in the pathogenesis of spontaneous canine diseases. Vet Immunol Immunopathol. 2012;147:6-24.
    • (2012) Vet Immunol Immunopathol , vol.147 , pp. 6-24
    • Spitzbarth, I.1    Baumgartner, W.2    Beineke, A.3
  • 46
    • 58149252377 scopus 로고    scopus 로고
    • Increase of pro-inflammatory cytokine expression in non-demyelinating early cerebral lesions in nervous canine distemper
    • Beineke A, Markus S, Borlak J, Thum T, Baumgärtner W. Increase of pro-inflammatory cytokine expression in non-demyelinating early cerebral lesions in nervous canine distemper. Viral Immunol. 2008;21:401-10.
    • (2008) Viral Immunol , vol.21 , pp. 401-410
    • Beineke, A.1    Markus, S.2    Borlak, J.3    Thum, T.4    Baumgärtner, W.5
  • 50
    • 77749251918 scopus 로고    scopus 로고
    • Adult-onset drug-refractory seizure disorder associated with anti-voltage-gated potassium-channel antibody
    • Barajas RF, Collins DE, Cha S, Geschwind MD. Adult-onset drug-refractory seizure disorder associated with anti-voltage-gated potassium-channel antibody. Epilepsia. 2010;51:473-7.
    • (2010) Epilepsia , vol.51 , pp. 473-477
    • Barajas, R.F.1    Collins, D.E.2    Cha, S.3    Geschwind, M.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.