Design and synthesis of butenolide-based amide derivatives as anti-inflammatory agents

Medicinal Chemistry Research

Volumn 24, Issue 11, 2015, Pages 3775-3784

  Ali, Yakub ^a   Alam, Mohammad Sarwar ^a   Hamid, Hinna ^a   Husain, Asif ^b   Dhulap, Abhijeet ^c   Bano, Sameena ^a   Kharbanda, Chetna ^a   Nazreen, Syed ^a   Haider, Saqlain ^a  

^a HAMDARD UNIVERSITY   (India)

^b HAMDARD UNIVERSITY   (India)

^c CSIR Unit for Research and Development of Information Products   (India)

Author keywords

Amide derivatives; Analgesic; Anti inflammatory; Hepatotoxicity; Immunohistochemistry; TNF ; Ulcerogenic

Indexed keywords

AMIDE; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; BUTENOLIDE; CYCLOOXYGENASE 2 INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOMETACIN; TUMOR NECROSIS FACTOR ALPHA;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; EX VIVO STUDY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; LIVER TOXICITY; MOLECULAR DOCKING; NONHUMAN; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STOMACH; STRUCTURE ACTIVITY RELATION; ULCEROGENESIS; WISTAR RAT;

EID: 84942502576     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-015-1404-y     Document Type: Article

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