메뉴 건너뛰기




Volumn 26, Issue 5, 2011, Pages 742-748

Synthesis and biological evaluation of some new pyridazinone derivatives

Author keywords

Analgesic; Anti inflammatory; Lipid peroxidation; Pyridazinone

Indexed keywords

5 (4 CHLORO BENZYL) 3 (4 CHLORO PHENYL) 1,6 DIHYDRO 6 PYRIDAZINONE; 5 (4 CHLORO BENZYL) 3 (4 METHYL PHENYL) 1,6 DIHYDRO 6 PYRIDAZINONE; 5 (4 FLUORO BENZYL) 3 (4 CHLORO PHENYL) 1,6 DIHYDRO 6 PYRIDAZINONE; 5 (4 FLUORO BENZYL) 3 (4 METHYL PHENYL) 1,6 DIHYDRO 6 PYRIDAZINONE; IBUPROFEN; METHYL GROUP; PYRIDAZINONE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 80052826491     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2010.548810     Document Type: Article
Times cited : (9)

References (17)
  • 1
    • 0035034031 scopus 로고    scopus 로고
    • Valdecoxib and Parecoxib sodium. Analgesic, antiarthritic, cyclooxygenase-2 inhibitor
    • DOI 10.1358/dof.2001.026.02.610299
    • Sorbera LA, Leeson P, Castaner J, Castaner RM. Valdecoxib and parecoxib sodium: analgesic, antiarthritic, cyclooxygenase-2 inhibitor. Drugs Future 2001;26:133-140. (Pubitemid 32372328)
    • (2001) Drugs of the Future , vol.26 , Issue.2 , pp. 133-140
    • Sorbera, L.A.1    Leeson, P.A.2    Castaner, J.3    Castaner, R.M.4
  • 5
    • 17144393290 scopus 로고    scopus 로고
    • Adverse cardiovascular efects of the coxibs
    • Dogné JM, Supuran CT, Pratico D. Adverse cardiovascular efects of the coxibs. J Med Chem 2005;48:2251-2257.
    • (2005) J Med Chem , vol.48 , pp. 2251-2257
    • Dogné, J.M.1    Supuran, C.T.2    Pratico, D.3
  • 6
    • 0023240562 scopus 로고
    • A novel class of cardiotonics. Synthesis and pharmacological properties of [4-(substituted-amino)phenyl]pyridazinones and related derivatives
    • Okushima H, Narimatsu A, Kobayashi M, Furuya R, Tsuda K, Kitada Y. A novel class of cardiotonics. Synthesis and pharmacological properties of [4-(substituted-amino)phenyl]pyridazinones and related derivatives. J Med Chem 1987;30:1157-1161. (Pubitemid 17117974)
    • (1987) Journal of Medicinal Chemistry , vol.30 , Issue.7 , pp. 1157-1161
    • Okushima, H.1    Narimatsu, A.2    Kobayashi, M.3
  • 7
    • 0022538127 scopus 로고
    • Dihydropyridazinone cardiotonics: The discovery and inotropic activity of 1,3-dihydro-3,3-dimethyl-5-(1,4,5,6-tetrahydro-6-oxo-3-pyrid azinyl)-2H-indol-2-one
    • Robertson DW, Krushinski JH, Beedle EE, Wyss V, Pollock GD, Wilson H et al. Dihydropyridazinone cardiotonics: the discovery and inotropic activity of 1,3-dihydro-3,3-dimethyl-5-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl) -2H-indol-2-one. J Med Chem 1986;29:1832-1840. (Pubitemid 16030281)
    • (1986) Journal of Medicinal Chemistry , vol.29 , Issue.10 , pp. 1832-1840
    • Robertson, D.W.1    Krushinski, J.H.2    Beedle, E.E.3
  • 8
    • 0019843130 scopus 로고
    • Studies on new antiulcer agents. I. Synthesis and antisecretory activity of pyridazine derivatives
    • Yamada T, Nobuhara Y, Shimamura H, Yoshihara K, Yamaguchi A, Ohki M. Studies on new antiulcer agents. I. Synthesis and antisecretory activity of pyridazine derivatives. Chem Pharm Bull 1981;29:3433-3439. (Pubitemid 12154611)
    • (1981) Chemical and Pharmaceutical Bulletin , vol.29 , Issue.12 , pp. 3433-3439
    • Yamada, T.1    Nobuhara, Y.2    Shimamura, H.3
  • 10
    • 0023949447 scopus 로고
    • Synthesis and analgesic efect of N-substituted 5-arylidene-6-methyl-3- (4H)-pyridazinones
    • Rubat C, Coudert P, Couquelet J, Bastide P, Bastide J. Synthesis and analgesic efect of N-substituted 5-arylidene-6-methyl-3-(4H)-pyridazinones. Chem Pharm Bull 1988;36:1558-1561.
    • (1988) Chem Pharm Bull , vol.36 , pp. 1558-1561
    • Rubat, C.1    Coudert, P.2    Couquelet, J.3    Bastide, P.4    Bastide, J.5
  • 11
    • 0024444033 scopus 로고
    • Synthesis and pharmacological evaluation of N-substituted 4,6-diaryl-3-pyridazinones as analgesic, antiinflammatory and antipyretic agents
    • Rubat C, Coudert P, Tronche P, Bastide J, Bastide P, Privat AM. Synthesis and pharmacological evaluation of N-substituted 4,6-diaryl-3-pyridazinones as analgesic, antiinfammatory and antipyretic agents. Chem Pharm Bull 1989;37:2832-2835. (Pubitemid 19279397)
    • (1989) Chemical and Pharmaceutical Bulletin , vol.37 , Issue.10 , pp. 2832-2835
    • Rubat, C.1    Coudert, P.2    Tronche, P.3    Bastide, J.4    Bastide, P.5    Privat, A.-M.6
  • 12
    • 68949149416 scopus 로고    scopus 로고
    • Synthesis, reactions and biological activity of 3-arylidene-5-(4- methylphenyl)-2(3H)-furanones
    • Husain A, Alam MM, Siddiqui N. Synthesis, reactions and biological activity of 3-arylidene-5-(4-methylphenyl)-2(3H)-furanones. J Serb Chem Soc 2009;74:103-115.
    • (2009) J Serb Chem Soc , vol.74 , pp. 103-115
    • Husain, A.1    Alam, M.M.2    Siddiqui, N.3
  • 13
    • 64249160971 scopus 로고    scopus 로고
    • Synthesis and pharmacological evaluation of 2(3H)-furanones and 2(3H)-pyrrolones, combining analgesic and anti-infammatory properties with reduced gastrointestinal toxicity and lipid peroxidation
    • Alam MM, Husain A, Hasan SM, Suruchi, Anwer T. Synthesis and pharmacological evaluation of 2(3H)-furanones and 2(3H)-pyrrolones, combining analgesic and anti-infammatory properties with reduced gastrointestinal toxicity and lipid peroxidation. Eur J Med Chem 2009;44:2636-2642.
    • (2009) Eur J Med Chem , vol.44 , pp. 2636-2642
    • Alam, M.M.1    Husain, A.2    Hasan, S.M.3    Suruchi, A.T.4
  • 14
    • 67249094291 scopus 로고
    • Carrageenin-induced edema in hind paw of the rat as an assay for antiifammatory drugs
    • Winter CA, Risley EA, Nuss GW. Carrageenin-induced edema in hind paw of the rat as an assay for antiifammatory drugs. Proc Soc Exp Biol Med 1962;111:544-547.
    • (1962) Proc Soc Exp Biol Med , vol.111 , pp. 544-547
    • Winter, C.A.1    Risley, E.A.2    Nuss, G.W.3
  • 15
    • 84873776176 scopus 로고
    • A method for evaluating both non-narcotic and narcotic analgesics
    • Siegmund E, Cadmus R, Lu G. A method for evaluating both non-narcotic and narcotic analgesics. Proc Soc Exp Biol Med 1957;95:729-731.
    • (1957) Proc Soc Exp Biol Med , vol.95 , pp. 729-731
    • Siegmund, E.1    Cadmus, R.2    Lu, G.3
  • 16
    • 0018667262 scopus 로고
    • The role of direct tissue contact in the production of gastrointestinal ulcers by anti-inflammatory drugs in rats
    • DOI 10.1016/0041-008X(79)90153-4
    • Cioli V, Putzolu S, Rossi V, Scorza Barcellona P, Corradino C. Te role of direct tissue contact in the production of gastrointestinal ulcers by anti-infammatory drugs in rats. Toxicol Appl Pharmacol 1979;50:283-289. (Pubitemid 10233388)
    • (1979) Toxicology and Applied Pharmacology , vol.50 , Issue.2 , pp. 283-289
    • Cioli, V.1    Putzolu, S.2    Rossi, V.3
  • 17
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • DOI 10.1016/0003-2697(79)90738-3
    • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:351-358. (Pubitemid 9194347)
    • (1979) Analytical Biochemistry , vol.95 , Issue.2 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.