Effect of polyphenol supplements on redox status of blood cells: a randomized controlled exercise training trial

European Journal of Nutrition

Volumn 54, Issue 7, 2015, Pages 1081-1093

  Carrera Quintanar, Lucrecia ^a   Funes, Lorena ^a   Vicente Salar, Nestor ^a   Blasco Lafarga, Cristina ^b   Pons, Antoni ^c,d   Micol, Vicente ^a,d   Roche, Enrique ^a,d  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

^c UNIVERSITAT DE LES ILLES BALEARS   (Spain)

^d Instituto de Salud Carlos III   (Spain)

Author keywords

Almond beverage; Lippia citriodora; Phenolic compounds; Weight lifting

Indexed keywords

ANTIOXIDANT; CATALASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; LIPPIA CITRIODORA EXTRACT; MANGANESE SUPEROXIDE DISMUTASE; PLANT EXTRACT; POLYPHENOL DERIVATIVE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; POLYPHENOL;

ADULT; ALMOND; ALOYSIA CITRODORA; ARTICLE; BEVERAGE; CONTROLLED STUDY; ENZYME ACTIVITY; EXERCISE; GENE EXPRESSION; HUMAN; LEUKOCYTE; LYMPHOCYTE; MALE; NEUTROPHIL; NORMAL HUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; ADIPOSE TISSUE; BIOASSAY; BLOOD CELL; BODY MASS; DIET; DIETARY SUPPLEMENT; DRUG EFFECTS; ERYTHROCYTE; METABOLISM; OXIDATION REDUCTION REACTION; SKELETAL MUSCLE; YOUNG ADULT;

ADIPOSE TISSUE; ANTIOXIDANTS; BLOOD CELLS; BODY MASS INDEX; CATALASE; DIET; DIETARY SUPPLEMENTS; ENDPOINT DETERMINATION; ERYTHROCYTES; EXERCISE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HUMANS; MALE; MUSCLE, SKELETAL; NEUTROPHILS; OXIDATION-REDUCTION; OXIDATIVE STRESS; POLYPHENOLS; SINGLE-BLIND METHOD; SUPEROXIDE DISMUTASE; YOUNG ADULT;

EID: 84942371302     PISSN: 14366207     EISSN: 14366215     Source Type: Journal    
DOI: 10.1007/s00394-014-0785-x     Document Type: Article

References (60)

1. McGinley C, Shafat A, Donnelly AE (2009) Does antioxidant vitamin supplementation protect against muscle damage? Sports Med 39:1011–1032
2. Morton JP, Kayani AC, McArdle A, Drust B (2009) The exercise-induced stress response of skeletal muscle, with specific emphasis on humans. Sports Med 39:643–662
3. Smith C, Kruger MJ, Smith RM, Myburgh KH (2008) The inflammatory response to skeletal muscle injury: illuminating complexities. Sports Med 38:947–969
4. Toumi H, F’guyer S, Best TM (2006) The role of neutrophils in injury and repair following muscle stretch. J Anat 208:459–470
5. Geering B, Simon HU (2011) Peculiarities of cell death mechanisms in neutrophils. Cell Death Differ 18:1457–1469
6. Tauler P, Aguilo A, Gimeno I, Noguera A, Agusti A, Tur JA, Pons A (2003) Differential response of lymphocytes and neutrophils to high intensity physical activity and to vitamin C diet supplementation. Free Radic Res 37:931–938
7. Cases N, Aguilo A, Tauler P, Sureda A, Llompart I, Pons A, Tur JA (2005) Differential response of plasma and immune cell’s vitamin E levels to physical activity and antioxidant vitamin supplementation. Eur J Clin Nutr 59:781–788
8. Moreira A, Delgado L, Moreira P, Haahtela T (2009) Does exercise increase the risk of upper respiratory tract infections? Br Med Bull 90:111–131
9. Gleeson M, Bishop NC (2000) Elite athlete immunology: importance of nutrition. Int J Sports Med 21(Suppl 1):S44–S50
10. Sen CK (2001) Antioxidants in exercise nutrition. Sports Med 31:891–908
11. Nikolaidis MG, Kerksick CM, Lamprecht M, McAnulty SR (2012) Does vitamin C and E supplementation impair the favourable adaptations of regular exercise? Oxid Med Cell Longev. doi:10.1155/2012/707941
12. Jakeman P, Maxwell S (1993) Effect of antioxidant vitamin supplementation on muscle function after eccentric exercise. Eur J Appl Phys Occup Physiol 67:426–430
13. Shafat A, Butler P, Jensen RI, Donnelly AE (2004) Effects of dietary supplementation with vitamins C and E on muscle function during and after eccentric contractions in humans. Eur J Appl Physiol 93:196–202
14. Gomez-Cabrera MC, Domenech E, Romagnoli M, Arduini A, Borras C, Pallardo FV, Sastre J, Viña J (2008) Oral administration of vitamin C decreases muscle mitochondria biogenesis and hampers training-induced adaptations in endurance performance. Am J Clin Nutr 87:142–149
15. Marshall RJ, Scott KC, Hill RC, Lewis DD, Sundstrom D, Jones GL, Harper J (2002) Supplemental vitamin C appears to slow racing greyhounds. J Nutr 132(Suppl 2):1616S–1621S
16. Bailey DM, Williams C, Betts JA, Thompson D, Hurst TL (2011) Oxidative stress, inflammation and recovery of muscle function after damaging exercise: effect of 6-week mixed antioxidant supplementation. Eur J Appl Physiol 111:925–936
17. Yfanti C, Akerstrom T, Nielsen S, Nielsen AR, Mounier R, Mortensen OH, Lykkesfeldt J, Rose AJ, Fischer CP, Pedersen BK (2010) Antioxidant supplementation does not alter endurance training adaptation. Med Sci Sports Exerc 42:1388–1395
18. Higashida K, Kim SH, Higuchi M, Holloszy JO, Han DH (2011) Normal adaptations to exercise despite protection against oxidative stress. Am J Physiol Endocrinol Metab 301:E779–E784
19. Elhaimeur F, Courderot-Masuyer C, Nicod L, Guyon C, Richert I, Berthelot A (2002) Dietary vitamin C supplementation decreases blood pressure in DOCA-salt hypertensive male Sprague-Dawley rats and this is associated with increased liver oxidative stress. Mol Cell Biochem 237:77–83
20. Nieman DC, Henson DA, McAnulty SR, McAnulty LS, Morrow JD, Ahmed A, Heward CB (2004) Vitamin E and immunity after the Kona Triathlon World Championship. Med Sci Sports Exerc 36:1328–1335
21. McAnulty SR, McAnulty LS, Nieman DC, Morrow JD, Shooter LA, Holmes S, Heward C, Henson DA (2005) Effect of alpha-tocopherol supplementation on plasma homocysteine and oxidative stress in highly trained athletes before and after exhaustive exercise. J Nutr Biochem 16:530–537
22. Close GL, Ashton T, Cable T, Doran D, Holloway C, McArdle F, McLaren DP (2006) Ascorbic acid supplementation does not attenuate post-exercise muscle soreness following muscle-damaging exercise but may delay the recovery process. Br J Nutr 95:976–981
23. Rytter E, Vessby B, Asgard R, Ersson C, Moussavian S, Sjödin A, Abramsson-Zetterberg L, Möller L, Basu S (2010) Supplementation with a combination of antioxidants does not affect glycaemic control, oxidative stress or inflammation in type 2 diabetes subjects. Free Radic Res 44:1445–1453
24. Theodorou AA, Nikolaidis MG, Paschalis V, Koutsias S, Panayiotou G, Fatouros IG, Koutedakis Y, Jamurtas AZ (2011) No effect of antioxidant supplementation on muscle performance and blood redox adaptations to eccentric training. Am J Clin Nutr 93:1373–1383
25. Niess AM, Simon P (2007) Response and adaptation of skeletal muscle to exercise: the role of reactive oxygen species. Front Biosci 12:4826–4838
26. Bucci LR (2000) Selected herbals and human exercise performance. Am J Clin Nutr 72(Suppl 2):624S–636S
27. Funes L, Fernandez-Arroyo S, Laporta O, Pons A, Roche E, Segura-Carretero A, Fernandez-Gutierrez A, Micol V (2009) Correlation between plasma antioxidant capacity and verbascoside levels in rats after oral administration of lemon verbena extracts. Food Chem 117:589–598
28. Carrera-Quintanar L, Funes L, Viudes E, Tur J, Micol V, Roche E, Pons A (2012) Antioxidant effect of lemon verbena extracts in lymphocytes of university students performing aerobic training program. Scand J Med Sci Sports 22:454–461
29. Funes L, Carrera-Quintanar L, Cerdan-Calero M, Ferrer MD, Drobnic F, Pons A, Roche E, Micol V (2011) Effect of lemon verbena supplementation on muscular damage markers, proinflammatory cytokines release and neutrophils’oxidative stress in chronic exercise. Eur J Appl Physiol 111:695–705
30. Sureda A, Tauler P, Aguilo A, Cases N, Llompart I, Tur JA, Pons A (2007) Antioxidant supplementation influences the neutrophil tocopherol associated protein expression, but not the inflammatory response to exercise. Cent Eur J Biol 2:56–70
31. Sureda A, Tauler P, Aguilo A, Cases N, Llompart I, Tur JA, Pons A (2008) Influence of an antioxidant vitamin-enriched drink on pre- and post-exercise lymphocyte antioxidant system. Ann Nutr Metab 52:233–240
32. Venkatachalam M, Sathe SK (2006) Chemical composition of selected edible nut seeds. J Agric Food Chem 54:4705–4714
33. Mestre-Alfaro A, Ferrer MD, Sureda A, Tauler P, Martinez E, Bibiloni MM, Micol V, Tur JA, Pons A (2011) Phytoestrogens enhance antioxidant enzymes after swimming exercise and modulate sex hormone plasma levels in female swimmers. Eur J Appl Physiol 111:2281–2294
34. Quirantes-Piné R, Herranz-López M, Funes L, Borrás-Linares I, Micol V, Segura-Carretero A, Fernández-Gutiérrez A (2013) Phenylpropanoids and their metabolites are the major compounds responsible for blood-cell protection against oxidative stress after administration of Lippia citriodora in rats. Phytomedicine 20:1112–1118
35. Marfell-Jones M, Olds T, Steward A, Carter L (2006) International standards for anthropometric assessment. ISAK, Potchefstroom
36. Boyum A (1964) Separation of white blood cells. Nature 204:793–794
37. Trinder P (1969) Determination of blood glucose using an oxidase–peroxidase system with a non-carcinogenic chromogen. J Clin Pathol 22:158–161
38. Bucolo G, David H (1973) Quantitative determination of serum triglycerides by the use of enzymes. Clin Chem 19:476–482
39. Fossati P, Prencipe L, Berti G (1980) Use of 3,5-dichloro-2-hydroxybenzenesulfonic acid/4-aminophenazone chromogenic system in direct enzymic assay of uric acid in serum and urine. Clin Chem 26:227–231
40. Bowers LD, Wong ET (1980) Kinetic serum creatineine assays. II. A critical evaluation and review. Clin Chem 26:555–561
41. Weisshaar D, Gossrau E, Faderl B (1975) Normal ranges of alpha-HBDH, LDH, AP, and LAP as measured with substrate-optimated test charges. Med Welt 26:387–392
42. Young DS, Friedman RB (2001) Effects of disease on clinical laboratory tests. AACC Press, Washington DC
43. McCord JM, Fridovich I (1969) Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J Biol Chem 244:6049–6055
44. Aebi H (1984) Catalase in vitro. Methods Enzymol 105:121–126
45. Flohé L, Gunzler WA (1984) Assays of glutathione peroxidase. Methods Enzymol 105:114–121
46. Goldberg DM, Spooner RJ (1985) Glutathione reductase. In: Bergmeyer HU (ed) Methods of enzymatic analysis. Verlag Chemie, Basel, pp 258–265
47. Levine RL, Williams JA, Stadtman ER, Shacter E (1994) Carbonyl assays for determination of oxidatively modified proteins. Methods Enzymol 233:346–357
48. Laporta O, Funes L, Garzon MT, Villalain J, Micol V (2007) Role of membranes on the antibacterial and anti-inflammatory activities of the bioactive compounds from hypoxis rooperi corm extract. Arch Biochem Biophys 467:119–131
49. (−ΔΔCt) method. Methods 25:402–408
50. Bloomer RJ (2008) Effect of exercise on oxidative stress biomarkers. Adv Clin Chem 46:1–50
51. Vander A, Sherman J, Luciano D (2001) Human physiology. McGraw Hill, Boston
52. Hausser J, Syed AP, Selevsek N, van Nimwegen E, Jaskiewick L, Aebersold R, Zavolan M (2013) Timescales and bottlenecks in miRNA-dependent gene regulation. Mol Syst Biol 9:711
53. Vogel C, Marcotte EM (2012) Insights into the regulation of protein abundance from proteomic and transcriptomic analyses. Nat Rev Genet 13:227–232
54. Serafini M, Miglio C, Peluso I, Petrosino T (2011) Modulation of plasma non enzimatic antioxidant capacity (NEAC) by plant foods: the role of polyphenols. Curr Top Med Chem 11:1821–1846
55. Yamada K, Tachibana H (2000) Recent topics in anti-oxidant factors. BioFactors 13:167–172
56. Osawa T (1999) Protective role of dietary polyphenols in oxidative stress. Mech Ageing Dev 111:133–139
57. Rice-Evans C (1995) Plant polyphenols: free radical scavengers or chain-breaking antioxidants? Biochem Soc Symp 61:103–116
58. Joven J, Rull A, Rodríguez-Gallego E, Camps J, Riera-Borrull M, Hernández-Aguilera A, Martín-Paredero V, Segura-Carretero A, Micol V, Alonso-Villaverde C, Menéndez JA (2013) Multifunctional targets of dietary polyphenols in disease: a case for chemokine network and energy metabolism. Food Chem Toxicol 51:267–279
59. Bouayed J, Bohn T (2010) Exogenous antioxidants, double-edge swords in cellular redox state. Oxid Med Cell Longev 3:228–237
60. Sureda A, Batle JM, Tauler P, Aguiló A, Cases N, Tur JA, Pons A (2004) Hypoxia/reoxygenation and vitamin C intake influence NO synthesis and antioxidant defenses of neutrophils. Free Radic Biol Med 37:1744–1755