Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades

Science

Volumn 349, Issue 6255, 2015, Pages 1525-1529

  Mutti, Francesco G ^a,c   Knaus, Tanja ^a,c   Scrutton, Nigel S ^a   Breuer, Michael ^b   Turner, Nicholas J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b BASF SE   (Germany)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DEHYDROGENASE; ALCOHOL DERIVATIVE; ALKANOL; AMINE; AMINE DEHYDROGENASE; AMMONIA; AROMATIC ALCOHOL; NITROGEN; UNCLASSIFIED DRUG; AROMATIC AMINE DEHYDROGENASE; HYDROGEN; OXIDOREDUCTASE;

ALCOHOL; ALIPHATIC HYDROCARBON; AMMONIUM; AROMATIC HYDROCARBON; BACTERIUM; ENZYME ACTIVITY; HYDROGEN; NITROGEN; NITROGEN COMPOUND; REDOX CONDITIONS;

AMINATION; ARTICLE; BACILLUS; BIOCATALYSIS; BIOTRANSFORMATION; CHIRALITY; ENANTIOSELECTIVITY; ENZYME ACTIVITY; ENZYME METABOLISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; HYDROGEN BORROWING AMINATION; LACTOBACILLUS; NONHUMAN; PH; PRIORITY JOURNAL; CHEMISTRY; ENZYMOLOGY; GENETIC ENGINEERING; GENETICS; SYNTHESIS;

BACILLUS SP.; LACTOBACILLUS SP.;

ALCOHOL DEHYDROGENASE; ALCOHOLS; AMINATION; AMINES; BACILLUS; BIOCATALYSIS; GENETIC ENGINEERING; HYDROGEN; LACTOBACILLUS; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS;

EID: 84942357824     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aac9283     Document Type: Article

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