Sepsis-induced selective parvalbumin interneuron phenotype loss and cognitive impairments may be mediated by NADPH oxidase 2 activation in mice

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Ji, Mu Huo ^a   Qiu, Li Li ^a   Tang, Hui ^a   Ju, Ling Sha ^a   Sun, Xiao Ru ^a   Zhang, Hui ^a   Jia, Min ^a   Zuo, Zhi Yi ^b   Shen, Jin Chun ^a   Yang, Jian Jun ^a  

^a NANJING UNIVERSITY   (China)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

Cognition; NADPH oxidase; Oxidative stress; Parvalbumin interneurons; Sepsis

Indexed keywords

4 HYDROXYNONENAL; APOCYNIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MALONALDEHYDE; PARVALBUMIN; POSTSYNAPTIC DENSITY PROTEIN 95; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; ACETOPHENONE DERIVATIVE; CYBB PROTEIN, MOUSE; MEMBRANE PROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CECAL LIGATION AND PUNCTURE-INDUCED SEPSIS; COGNITION; COHORT ANALYSIS; CONTROLLED STUDY; ENZYME ACTIVATION; FEAR; INTERNEURON; MALE; MOUSE; NONHUMAN; OPEN FIELD BEHAVIOR; OXIDATIVE STRESS; PHENOTYPE; PROTEIN EXPRESSION; SEPSIS ASSOCIATED ENCEPHALOPATHY; SHAM PROCEDURE; SURVIVAL RATE; ANIMAL; C57BL MOUSE; CELL CULTURE; COGNITION DISORDERS; COMPLICATION; CONDITIONING; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; EXPLORATORY BEHAVIOR; HIPPOCAMPUS; METABOLISM; NERVE CELL; PATHOLOGY; PSYCHOLOGY; SEPSIS;

ACETOPHENONES; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELLS, CULTURED; COGNITION DISORDERS; CONDITIONING (PSYCHOLOGY); DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; FEAR; HIPPOCAMPUS; INTERNEURONS; MALE; MALONDIALDEHYDE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; NADPH OXIDASE; NEURONS; OXIDATIVE STRESS; PARVALBUMINS; SEPSIS; SUPEROXIDE DISMUTASE;

EID: 84942318401     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0401-x     Document Type: Article

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