Expression and role of neuroglobin in rats with sepsis-associated encephalopathy

Critical Care Medicine

Volumn 42, Issue 1, 2014, Pages

  Zhang, Li Na ^a   Ai, Yu Hang ^a   Gong, Hua ^a   Guo, Qu Lian ^a   Huang, Li ^a   Liu, Zhi Yong ^a   Yao, Bo ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

cecal ligation and puncture; hemin; neuroglobin; sepsis associated encephalopathy

Indexed keywords

HEMIN; MALONALDEHYDE; NEUROGLOBIN; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD ANALYSIS; BRAIN; BRAIN DISEASE; CONTROLLED STUDY; ELECTROENCEPHALOGRAPH; ENZYME LINKED IMMUNOSORBENT ASSAY; EVOKED RESPONSE; GENE EXPRESSION; IMMUNOREACTIVITY; MALE; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEPSIS;

EID: 84891526402     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3182a63b1a     Document Type: Article

References (22)

1. Zhang LN, Wang XT, Ai YH, et al: Epidemiological features and risk factors of sepsis-associated encephalopathy in intensive care unit patients: 2008-2011. Chin Med J (Engl) 2012; 125:828-831
2. Chelazzi C, Consales G, De Gaudio AR: Sepsis associated encephalopathy. Curr Anaesthesia Crit Care 2008; 19:15-21
3. Sun Y, Jin K, Mao XO, et al: Neuroglobin is up-regulated by and protects neurons from hypoxic-ischemic injury. Proc Natl Acad Sci USA 2001; 98:15306-15311
4. Sun Y, Jin K, Peel A, et al: Neuroglobin protects the brain from experimental stroke in vivo. Proc Natl Acad Sci USA 2003; 100:3497-3500
5. Shang A, Zhou D, Wang L, et al: Increased neuroglobin levels in the cerebral cortex and serum after ischemia-reperfusion insults. Brain Res 2006; 1078:219-226
6. Du XG, Guang P, Chen XM, et al: A quantitative study of neuroglobin in cerebral cortex after traumatic brain injury in rats. Chin J Forensic Med 2005; 21:129-132
7. Sun JL, Sun ZY: Expression of Ngb and HIF-1 in brain tissue of post-resuscitation rats. Chin J Crit Care Med 2011; 31:819-822
8. Zhu Y, Sun Y, Jin K, et al: Hemin induces neuroglobin expression in neural cells. Blood 2002; 100:2494-2498
9. Fang J, Qin H, Seki T, et al: Therapeutic potential of pegylated hemin for reactive oxygen species-related diseases via induction of heme oxygenase-1: Results from a rat hepatic ischemia/reperfusion injury model. J Pharmacol Exp Ther 2011; 339:779-789
10. Bortscher S, Chang J, Vilz TO, et al: Hemin induction of HO-1 protects against LPS-induced septic ileus. J Surg Res 2012; 178:866-873
11. Li RC, Guo SZ, Lee SK, et al: Neuroglobin protects against oxidative stress in global ischemia. J Cereb Blood Flow Metab 2010; 30:1874-1882
12. Sharshar T, Polito A, Checinski A, et al: Septic-associated encephalopathy-Everything starts at a microlevel. Crit Care 2010; 14:199
13. Wichterman KA, Baue AE, Chaudry IH: Sepsis and septic shock-A review of laboratory models and a proposal. J Surg Res 1980; 29:189-201
14. Paxinos G, Watson C: The Rat Brain in Stereotaxic Coordinates. San Diego, CA, Academic Press, 1998
15. Fromowitz FB, Viola MV, Chao S, et al: ras p21 expression in the progression of breast cancer. Hum Pathol 1987; 18:1268-1275
16. Kafa IM, Uysal M, Bakirci S, et al: Sepsis induces apoptotic cell death in different regions of the brain in a rat model of sepsis. Acta Neurobiol Exp (Wars) 2010; 70:246-260
17. Jin K, Mao XO, Xie L, et al: Pharmacological induction of neuroglobin expression. Pharmacology 2011; 87:81-84
18. De Marinis E, Ascenzi P, Pellegrini M, et al: 17-estradiol-A new modulator of neuroglobin levels in neurons: Role in neuroprotection against H2O2-induced toxicity. Neurosignals 2010; 18:223-235
19. Cai B, Lin Y, Xue XH, et al: TAT-mediated delivery of neuroglobin protects against focal cerebral ischemia in mice. Exp Neurol 2011; 227:224-231
20. Wei X, Yu Z, Cho KS, et al: Neuroglobin is an endogenous neuroprotectant for retinal ganglion cells against glaucomatous damage. Am J Pathol 2011; 179:2788-2797
21. Pesce A, Bolognesi M, Bocedi A, et al: Neuroglobin and cytoglobin. Fresh blood for the vertebrate globin family. EMBO Rep 2002; 3:1146-1151
22. Raychaudhuri S, Skommer J, Henty K, et al: Neuroglobin protects nerve cells from apoptosis by inhibiting the intrinsic pathway of cell death. Apoptosis 2010; 15:401-411