Effects of bone marrow‑derived mesenchymal stem cells transfected with survivin on pulmonary fibrosis in mice

Experimental and Therapeutic Medicine

Volumn 10, Issue 5, 2015, Pages 1857-1864

  Zhou, Mi ^a   Chen, Dong Ling ^a   Jiang, Tao ^a   Feng, Yan Mei ^a   Han, Xiao Li ^a  

^a THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Mesenchymal stem cells; Mice; Pulmonary fibrosis; Survivin

Indexed keywords

CASPASE 3; CASPASE 9; GELATINASE B; GREEN FLUORESCENT PROTEIN; HYDROXYPROLINE; LIPOCORTIN 5; MESSENGER RNA; SURFACTANT PROTEIN A; SURVIVIN; TRANSFORMING GROWTH FACTOR BETA1; VIRUS VECTOR;

AGAR GEL ELECTROPHORESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEOMYCIN-INDUCED PULMONARY FIBROSIS; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CELL INFILTRATION; CELL VIABILITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; LUNG FIBROSIS; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; WESTERN BLOTTING;

EID: 84942255237     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2015.2715     Document Type: Article

References (32)

1. Liu X, Qian L, Nan HY, Cui M, Hao XY and Du YF: Function of the transforming growth factor-β 1/c-Jun N-terminal kinase signaling pathway in the action of thalidomide on a rat model of pulmonary fibrosis. Exp Ther Med 7: 669-674, 2014.
2. Moodley Y, Atienza D, Manuelpillai U, Samuel CS, Tchongue J, Ilancheran S, Boyd R and Trounson A: Human umbilical cord mesenchymal stem cells reduce fibrosis of bleomycin-induced lung injury. Am J Pathol 175: 303-313, 2009.
3. Selman M, King TE and Pardo A: Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med 134: 136-151, 2001.
4. Ortiz LA, Gambelli F, McBride C, Gaupp D, Baddo M, Kaminski N and Phinney DG: Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects. Proc Natl Acad Sci USA 100: 8407-8411, 2003.
5. Zhang ZH, Lu Y, Luan Y and Zhao JJ: Effect of bone marrow mesenchymal stem cells on experimental pulmonary arterial hypertension. Exp Ther Med 4: 839-843, 2012.
6. Kondo K, Shintani S, Shibata R, Murakami H, Murakami R, Imaizumi M, Kitagawa Y and Murohara T: Implantation of adipose-derived regenerative cells enhances ischemia-induced angiogenesis. Arterioscler Thromb Vasc Biol 29: 61-66, 2009.
7. Tzouvelekis A, Harokopos V, Paparountas T, Oikonomou N, Chatziioannou A, Vilaras G, Tsiambas E, Karameris A, Bouros D and Aidinis V: Comparative expression profiling in pulmonary fibrosis suggests a role of hypoxia-inducible factor-1α in disease pathogenesis. Am J Respir Crit Care Med 176: 1108-1119, 2007.
8. Wu Z, Wang X, Yang R, Liu Y, Zhao W, Si J, Ma X, Su C, Liu Y, Tan Y, Liu W, et al: Effects of carbon ion beam irradiation on lung injury and pulmonary fibrosis in mice. Exp Ther Med 5: 771-776, 2013.
9. Sun YW, Li BP, Wang Xuan, Zhang L, Lu PY and Zhao XY: Oriented migration of intravenously administrated mesenchymal stem cells transfected with adenovirus vector mediated green fluorescence protein in the lung tissue of pulmonary emphysema rats. Zhongguo Zu Zhi Gong Cheng Yan Jiu Yu Lin Chuang Kang Fu 14: 2528-2532, 2010 (In Chinese).
10. Cai Y: Pulmonary fibrosis drug treatment progress. Shi Jie Lin Chuang Yao Wu 29: 17-19, 2008 (In Chinese).
11. Liu T, Xie M, Wang HL and Ling W: Effect of matrine and IFN-γ on bleomycin-induced pulmonary fibrosis. Nanjing Yi Ke Da Xue Xue Bao 28: 592-596, 2008 (In Chinese).
12. Bhatt N, Baran C, Allen J, Magro C and Marsh CB: Promising pharmacologic innovations in treating pulmonary fibrosis. Curr Opin Pharmacol 6: 284-292, 2006.
13. Lettieri CJ, Veerappan GR, Helman DL, Mulligan CR and Shorr AF: Outcomes and safety of surgical lung biopsy for interstitial lung disease. Chest 127: 1600-1605, 2005.
14. Hu F: Research progress of Chinese medicine treatment of pulmonary fibrosis. Yi Yao Dao Bao 11: 1471-1474, 2011 (In Chinese).
15. Xu L, Xiao W, Ma DD, Zhou SY and Zhang QH: Ulcerative colitis combined with acute interstitial lung disease and airway disease: A case report and literature review. Exp Ther Med 8: 1229-1236, 2014.
16. Kotton DN, Ma BY, Cardoso WV, Sanderson EA, Summer RS, Williams MC and Fine A: Bone marrow-derived cells as progenitors of lung alveolar epithelium. Development 128: 5181-5188, 2001.
17. Krause DS, Theise ND, Collector MI, Henegariu O, Hwang S, Gardner R, Neutzel S and Sharkis SJ: Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell 105: 369-377, 2001.
18. Teke T, Maden E, Kiyici A, Korkmaz C, Gok Z, Ozer F, Imecik O and Uzun K: Cigarette smoke and bleomycin-induced pulmonary oxidative stress in rats. Exp Ther Med 4: 121-124, 2012.
19. Tzouvelekis A, Antoniadis A and Bouros D: Stem cell therapy in pulmonary fibrosis. Curr Opin Pulm Med 17: 368-373, 2011.
20. Cui A, Dai HP and Dai JW: Effects of bone marrow mesenchymal stem cells on bleomycin induced pulmonary fibrosis in rats. Zhonghua Jie He He Hu Xi Za Zhi 30: 677-682, 2007 (In Chinese).
21. Rojas M, Xu J, Woods CR, Spears W, Roman J and Brigham KL: Bone marrow-derived mesenchymal stem cells in repair of the injured lung. Am J Respir Cell Mol Biol 33: 145-152, 2005.
22. Beardmore VA, Ahonen LJ, Gorbsky GJ and Kallio MJ: Survivin dynamics increases at centromeres during G2/M phase transition and is regulated by microtubule-attachment and Aurora B kinase activity. J Cell Sci 117: 4033-4042, 2004.
23. Yang M, Liu Y, Lu S, Wang Z, Wang R, Zi Y and Li J: Analysis of the expression levels of surviving and VEGF in patients with acute lymphoblastic leukemia. Exp Ther Med 5: 305-307, 2013.
24. Liu F, Liu S, He S, Xie Z, Zu X and Jiang Y: Survivin transcription is associated with P-glycoprotein/MDR1 over expression in the multidrug resistance of MCF-7 breast cancer cells. Oncol Rep 23: 1469-1475, 2010.
25. Chen Y, Ma N, Mei J, Xiao HB, Lu SW, Xu HY and Zhong H: In vitro induction of human bone marrow mesenchymal stem cells to differentiate into type Ⅱ alveolar epithelial cells. Zhong Guo Zu Zhi Gong Cheng Yan Jiu 16: 1737-1741, 2012 (In Chinese).
26. Guo T, Fang M, Zhang D and Li X: Combination treatment with asiaticoside and repamycin: A new hope for in-stent restenosis. Exp Ther Med 6: 557-561, 2013.
27. Jiang PC, Xiong WP, Wang G, Ma C, Yao WQ, Kendell SF, Mehling BM, Yuan XH and Wu DC: A clinical trial report of autologous bone marrow-derived mesenchymal stem cell transplantation in patients with spinal cord injury. Exp Ther Med 6: 140-146, 2013.
28. Rubio D, Garcia S, Paz MF, De la Cueva T, Lopez-Fernandez LA, Lloyd AC, Garcia-Castro J and Bernad A: Molecular characterization of spontaneous mesenchymal stem cell transformation. PLoS One 3: e1398, 2008.
29. de la Fuente R, Bernad A, Garcia-Castro J, Martin MC and Cigudosa JC: Retraction: Spontaneous human adult stem cell transformation. Cancer Res 70: 6682, 2010.
30. Lin ZX and Xu H: Current understanding into the biological characteristics of mesenchymal stem cells. Zhongguo Zu Zhi Gong Cheng Yan Jiu Yu Lin Chuang Kang Fu 15: 3577-3580, 2011 (In Chinese).
31. Wang LZ, Xu L, Tan DM and Tan Y: The progress of survivin. Yi Xue Zong Shu 12: 1089-1092, 2006 (In Chinese).
32. Kobayashi M, Huang CL, Sonobe M, Kikuchi R, Ishikawa M, Kitamura J, Miyahara R, Menju T, Iwakiri S, Itoi K, Yasumizu R and Date H: Intratumoral Wnt2B expression affects tumor proliferation and survival in malignant pleural mesothelioma patients. Exp Ther Med 3: 952-958, 2012.