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Volumn 16, Issue 15, 2015, Pages 2319-2330

Bedaquiline and delamanid in tuberculosis

Author keywords

bedaquiline; children; delamanid; extensively drug resistant tuberculosis; multidrugresistant tuberculosis; pediatric tuberculosis; tuberculosis

Indexed keywords

BEDAQUILINE; DELAMANID; NITROIMIDAZOLE DERIVATIVE; OPC-67683; OXAZOLE DERIVATIVE; QUINOLINE DERIVATIVE; TUBERCULOSTATIC AGENT;

EID: 84942193941     PISSN: 14656566     EISSN: 17447666     Source Type: Journal    
DOI: 10.1517/14656566.2015.1080240     Document Type: Review
Times cited : (52)

References (99)
  • 1
    • 84930510601 scopus 로고    scopus 로고
    • Facing multidrug resistant tuberculosis
    • Sotgiu G, Migliori GB. Facing multidrug resistant tuberculosis. Pulm Pharmacol Ther 2014;32:144-8
    • (2014) Pulm Pharmacol Ther , vol.32 , pp. 144-148
    • Sotgiu, G.1    Migliori, G.B.2
  • 2
    • 0032821532 scopus 로고    scopus 로고
    • Studies on the treatment of tuberculosis undertaken by the British Medical Research Council tuberculosis units, 1946-1986, with relevant subsequent publications
    • Fox W, Ellard GA, Mitchison DA. Studies on the treatment of tuberculosis undertaken by the British Medical Research Council tuberculosis units, 1946-1986, with relevant subsequent publications. Int J Tuberc Lung Dis 1999;3(10 Suppl 2):S231-79
    • (1999) Int J Tuberc Lung Dis , vol.3 , Issue.10 , pp. S231-S279
    • Fox, W.1    Ellard, G.A.2    Mitchison, D.A.3
  • 3
  • 4
    • 0035967245 scopus 로고    scopus 로고
    • Interactions among drugs for HIV and opportunistic infections
    • Piscitelli SC, Gallicano KD. Interactions among drugs for HIV and opportunistic infections. N Engl J Med 2001;344:984-96
    • (2001) N Engl J Med , vol.344 , pp. 984-996
    • Piscitelli, S.C.1    Gallicano, K.D.2
  • 6
    • 38949210772 scopus 로고    scopus 로고
    • Culture-confirmed childhood tuberculosis in Cape Town, South Africa: A review of 596 cases
    • Schaaf HS, Marais BJ, Whitelaw A, et al. Culture-confirmed childhood tuberculosis in Cape Town, South Africa: A review of 596 cases. BMC Infect Dis 2007;7:140
    • (2007) BMC Infect Dis , vol.7 , pp. 140
    • Schaaf, H.S.1    Marais, B.J.2    Whitelaw, A.3
  • 7
    • 84888112787 scopus 로고    scopus 로고
    • Recent advances in tuberculosis: New drugs and treatment regimens
    • Sloan DJ, Davies GR, Khoo SH. Recent advances in tuberculosis: new drugs and treatment regimens. Curr Respir Med Rev 2013;9:200-10
    • (2013) Curr Respir Med Rev , vol.9 , pp. 200-210
    • Sloan, D.J.1    Davies, G.R.2    Khoo, S.H.3
  • 8
    • 84878434964 scopus 로고    scopus 로고
    • Drug-resistant tuberculosis: Time for visionary political leadership
    • Abubakar I, Zignol M, Falzon D, et al. Drug-resistant tuberculosis: time for visionary political leadership. Lancet Infect Dis 2013;13:529-39
    • (2013) Lancet Infect Dis , vol.13 , pp. 529-539
    • Abubakar, I.1    Zignol, M.2    Falzon, D.3
  • 9
    • 84892472865 scopus 로고    scopus 로고
    • Mutation rate and the emergence of drug resistance in mycobacterium tuberculosis
    • McGrath M, Gey van Pittius NC, et al. Mutation rate and the emergence of drug resistance in Mycobacterium tuberculosis. J Antimicrob Chemother 2014;69:292-302
    • (2014) J Antimicrob Chemother , vol.69 , pp. 292-302
    • McGrath, M.1    Gey Van Pittius, N.C.2
  • 11
    • 84925369382 scopus 로고    scopus 로고
    • Totally drug-resistant tuberculosis and adjunct therapies
    • Parida SK, Axelsson-Robertson R, Rao MV, et al. Totally drug-resistant tuberculosis and adjunct therapies. J Intern Med 2014;277(4):388-405
    • (2014) J Intern Med , vol.277 , Issue.4 , pp. 388-405
    • Parida, S.K.1    Axelsson-Robertson, R.2    Rao, M.V.3
  • 12
    • 84914701171 scopus 로고    scopus 로고
    • WHO,World Health Organization, Geneva,[Last accessed 6 May 2014]
    • WHO. Global tuberculosis report 2014. World Health Organization, Geneva, 2014. Available from: http://apps.who. int/iris/bitstream/10665/112360/1/ 9789241548748-eng.pdf [Last accessed 6 May 2014]
    • (2014) Global Tuberculosis Report , vol.2014
  • 13
    • 84898902322 scopus 로고    scopus 로고
    • On Behalf of the Sentinel Project on Pediatric Drug-Resistant Tuberculosis. Consensus statement on research definitions for drug-resistant tuberculosis in children
    • Seddon JA, Perez-Velez CM, Schaaf HS, et al. On Behalf of the Sentinel Project on Pediatric Drug-Resistant Tuberculosis. Consensus statement on research definitions for drug-resistant tuberculosis in children. J Pediatric Infect Dis Soc 2013;2:100-9
    • (2013) J Pediatric Infect Dis Soc , vol.2 , pp. 100-109
    • Seddon, J.A.1    Perez-Velez, C.M.2    Schaaf, H.S.3
  • 14
    • 84896029986 scopus 로고    scopus 로고
    • The medical and surgical treatment of drug-resistant tuberculosis
    • Calligaro GL, Moodley L, Symons G, et al. The medical and surgical treatment of drug-resistant tuberculosis. J Thorac Dis 2014;6:186-95
    • (2014) J Thorac Dis , vol.6 , pp. 186-195
    • Calligaro, G.L.1    Moodley, L.2    Symons, G.3
  • 15
  • 16
    • 84898751124 scopus 로고    scopus 로고
    • Extensively drug-resistant tuberculosis: Epidemiology and management
    • Matteelli A, Roggi A, Carvalho AC. Extensively drug-resistant tuberculosis: epidemiology and management. Clin Epidemiol 2014;6:111-18
    • (2014) Clin Epidemiol , vol.6 , pp. 111-118
    • Matteelli, A.1    Roggi, A.2    Carvalho, A.C.3
  • 17
    • 35548965671 scopus 로고    scopus 로고
    • First tuberculosis cases in Italy resistant to all tested drugs
    • Migliori GB, De Iaco G, Besozzi G, et al. First tuberculosis cases in Italy resistant to all tested drugs. Euro Surveill 2007;12:E070517.1
    • (2007) Euro Surveill , vol.12 , pp. E0705171
    • Migliori, G.B.1    De Iaco, G.2    Besozzi, G.3
  • 18
    • 84880162469 scopus 로고    scopus 로고
    • Resistance to fluoroquinolones and second-line injectable drugs: Impact on multidrug-resistant TB outcomes
    • Falzon D, Gandhi N, Migliori GB, et al. Resistance to fluoroquinolones and second-line injectable drugs: impact on multidrug-resistant TB outcomes. Eur Respir J 2013;42:156-68
    • (2013) Eur Respir J , vol.42 , pp. 156-168
    • Falzon, D.1    Gandhi, N.2    Migliori, G.B.3
  • 19
    • 84896273239 scopus 로고    scopus 로고
    • Drug resistance among tuberculosis cases in the European Union and European Economic Area, 2007 to 2012
    • van der Werf MJ, Kodmon C, Hollo V, et al. Drug resistance among tuberculosis cases in the European Union and European Economic Area, 2007 to 2012. Euro Surveill 2014;19:20733
    • (2014) Euro Surveill , vol.19 , pp. 20733
    • Van Der Werf, M.J.1    Kodmon, C.2    Hollo, V.3
  • 20
    • 60749083864 scopus 로고    scopus 로고
    • Treatment outcomes among patients with multidrug-resistant tuberculosis: Systematic review and meta-analysis
    • Orenstein EW, Basu S, Shah NS, et al. Treatment outcomes among patients with multidrug-resistant tuberculosis: systematic review and meta-analysis. Lancet Infect Dis 2009;9:153-61
    • (2009) Lancet Infect Dis , vol.9 , pp. 153-161
    • Orenstein, E.W.1    Basu, S.2    Shah, N.S.3
  • 22
    • 84896455574 scopus 로고    scopus 로고
    • New antituberculosis drugs, regimens, and adjunct therapies: Needs, advances, and future prospects
    • Zumla AI, Gillespie SH, Hoelscher M, et al. New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects. Lancet Infect Dis 2014;14:327-40
    • (2014) Lancet Infect Dis , vol.14 , pp. 327-340
    • Zumla, A.I.1    Gillespie, S.H.2    Hoelscher, M.3
  • 23
    • 77953842683 scopus 로고    scopus 로고
    • Current development and future prospects in chemotherapy of tuberculosis
    • Nuermberger EL, Spigelman MK, Yew WW. Current development and future prospects in chemotherapy of tuberculosis. Respirology 2010;15:764-78
    • (2010) Respirology , vol.15 , pp. 764-778
    • Nuermberger, E.L.1    Spigelman, M.K.2    Yew, W.W.3
  • 24
    • 77951782678 scopus 로고    scopus 로고
    • Rip Van Winkle wakes up: Development of tuberculosis treatment in the 21st century
    • Burman WJ. Rip Van Winkle wakes up: development of tuberculosis treatment in the 21st century. Clin Infect Dis 2010;50(Suppl 3):S165-72
    • (2010) Clin Infect Dis , vol.50 , pp. S165-S172
    • Burman, W.J.1
  • 25
    • 84897579469 scopus 로고    scopus 로고
    • Tuberculosis: Clinical trials and new drug regimens
    • Kwon YS, Jeong BH, Koh WJ. Tuberculosis: clinical trials and new drug regimens. Curr Opin Pulm Med 2014;20:280-6
    • (2014) Curr Opin Pulm Med , vol.20 , pp. 280-286
    • Kwon, Y.S.1    Jeong, B.H.2    Koh, W.J.3
  • 26
    • 84863584732 scopus 로고    scopus 로고
    • New drugs for the treatment of tuberculosis: Hope and reality
    • Grosset JH, Singer TG, Bishai WR. New drugs for the treatment of tuberculosis: hope and reality. Int J Tuberc Lung Dis 2012;16:1005-14
    • (2012) Int J Tuberc Lung Dis , vol.16 , pp. 1005-1014
    • Grosset, J.H.1    Singer, T.G.2    Bishai, W.R.3
  • 27
    • 84914705953 scopus 로고    scopus 로고
    • Respiratory review of 2014: Tuberculosis and nontuberculous mycobacterial pulmonary disease
    • Park CK, Kwon YS. Respiratory review of 2014: tuberculosis and nontuberculous mycobacterial pulmonary disease. Tuberc Respir Dis (Seoul) 2014;77:161-6
    • (2014) Tuberc Respir Dis (Seoul) , vol.77 , pp. 161-166
    • Park, C.K.1    Kwon, Y.S.2
  • 28
    • 78449274705 scopus 로고    scopus 로고
    • Drugs in development for tuberculosis
    • Ginsberg AM. Drugs in development for tuberculosis. Drugs 2010;70:2201-14
    • (2010) Drugs , vol.70 , pp. 2201-2214
    • Ginsberg, A.M.1
  • 30
    • 84860295215 scopus 로고    scopus 로고
    • Tuberculosis: The drug development pipeline at a glance
    • Villemagne B, Crauste C, Flipo M, et al. Tuberculosis: the drug development pipeline at a glance. Eur J Med Chem 2012;51:1-16
    • (2012) Eur J Med Chem , vol.51 , pp. 1-16
    • Villemagne, B.1    Crauste, C.2    Flipo, M.3
  • 31
    • 84895109493 scopus 로고    scopus 로고
    • Bedaquiline-The first ATP synthase inhibitor against multi drug resistant tuberculosis
    • Lakshmanan M, Xavier AS. Bedaquiline-The first ATP synthase inhibitor against multi drug resistant tuberculosis. J Young Pharm 2013;5:112-15
    • (2013) J Young Pharm , vol.5 , pp. 112-115
    • Lakshmanan, M.1    Xavier, A.S.2
  • 32
    • 84892762434 scopus 로고    scopus 로고
    • Bedaquiline: A novel drug to combat multiple drug-resistant tuberculosis
    • Goel D. Bedaquiline: A novel drug to combat multiple drug-resistant tuberculosis. J Pharmacol Pharmacother 2014;5:76-8
    • (2014) J Pharmacol Pharmacother , vol.5 , pp. 76-78
    • Goel, D.1
  • 33
    • 21844435978 scopus 로고    scopus 로고
    • The F1Fo-ATP synthase of Mycobacterium smegmatis is essential for growth
    • Tran SL, Cook GM. The F1Fo-ATP synthase of Mycobacterium smegmatis is essential for growth. J Bacteriol 2005;187:5023-8
    • (2005) J Bacteriol , vol.187 , pp. 5023-5028
    • Tran, S.L.1    Cook, G.M.2
  • 34
    • 80051850771 scopus 로고    scopus 로고
    • Probing the interaction of the diarylquinoline TMC207 with its target mycobacterial ATP synthase
    • Haagsma AC, Podasca I, Koul A, et al. Probing the interaction of the diarylquinoline TMC207 with its target mycobacterial ATP synthase. PLoS ONE 2011;6:e23575
    • (2011) PLoS ONE , vol.6 , pp. e23575
    • Haagsma, A.C.1    Podasca, I.2    Koul, A.3
  • 35
    • 84889076146 scopus 로고    scopus 로고
    • An update on the chemistry and medicinal chemistry of novel antimycobacterial compounds
    • Branco FS, Pinto AC, Boechat N. An update on the chemistry and medicinal chemistry of novel antimycobacterial compounds. Curr Top Med Chem 2013;13:2808-49
    • (2013) Curr Top Med Chem , vol.13 , pp. 2808-2849
    • Branco, F.S.1    Pinto, A.C.2    Boechat, N.3
  • 36
    • 84904260030 scopus 로고    scopus 로고
    • Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism
    • Koul A, Vranckx L, Dhar N, et al. Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism. Nat Commun 2014;5:3369
    • (2014) Nat Commun , vol.5 , pp. 3369
    • Koul, A.1    Vranckx, L.2    Dhar, N.3
  • 37
    • 84908226003 scopus 로고    scopus 로고
    • A Mycobacterium tuberculosis cytochrome bd oxidase mutant is hypersensitive to bedaquiline
    • Berney M, Hartman TE, Jacobs WR Jr. A Mycobacterium tuberculosis cytochrome bd oxidase mutant is hypersensitive to bedaquiline. MBio 2014;5:e01275-14
    • (2014) MBio , vol.5 , pp. e01275-e01314
    • Berney, M.1    Hartman, T.E.2    Jacobs, W.R.J.R.3
  • 38
    • 19944429772 scopus 로고    scopus 로고
    • A diarylquinoline drug active on the atp synthase of mycobacterium tuberculosis
    • Andries K, Verhasselt P, Guillemont J, et al. A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis. Science 2005;307:223-7
    • (2005) Science , vol.307 , pp. 223-227
    • Andries, K.1    Verhasselt, P.2    Guillemont, J.3
  • 39
    • 84857157134 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of TMC207 and its N-desmethyl metabolite in a murine model of tuberculosis
    • Rouan M-C, Lounis N, Gevers T, et al. Pharmacokinetics and pharmacodynamics of TMC207 and its N-desmethyl metabolite in a murine model of tuberculosis. Antimicrob Agents Chemother 2012;56:1444-51
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 1444-1451
    • Rouan, M.-C.1    Lounis, N.2    Gevers, T.3
  • 40
    • 84876269304 scopus 로고    scopus 로고
    • Randomized dose-ranging study of the 14-day early bactericidal activity of bedaquiline (TMC207) in patients with sputum microscopy smear-positive pulmonary tuberculosis
    • Diacon AH, Dawson R, Von Groote-Bidlingmaier F, et al. Randomized dose-ranging study of the 14-day early bactericidal activity of bedaquiline (TMC207) in patients with sputum microscopy smear-positive pulmonary tuberculosis. Antimicrob Agents Chemother 2013;57:2199-203
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 2199-2203
    • Diacon, A.H.1    Dawson, R.2    Von Groote-Bidlingmaier, F.3
  • 41
    • 48749120676 scopus 로고    scopus 로고
    • Early bactericidal activity and pharmacokinetics of the diarylquinoline TMC207 in treatment of pulmonary tuberculosis
    • Rustomjee R, Diacon AH, Allen J, et al. Early bactericidal activity and pharmacokinetics of the diarylquinoline TMC207 in treatment of pulmonary tuberculosis. Antimicrob Agents Chemother 2008;52:2831-5
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 2831-2835
    • Rustomjee, R.1    Diacon, A.H.2    Allen, J.3
  • 42
    • 84926435138 scopus 로고    scopus 로고
    • Rifampicin and rifapentine significantly reduce concentrations of bedaquiline, a new anti-TB drug
    • Svensson EM, Murray S, Karlsson MO, Dooley KE. Rifampicin and rifapentine significantly reduce concentrations of bedaquiline, a new anti-TB drug. J Antimicrob Chemother 2015;70:1106-14
    • (2015) J Antimicrob Chemother , vol.70 , pp. 1106-1114
    • Svensson, E.M.1    Murray, S.2    Karlsson, M.O.3    Dooley, K.E.4
  • 43
    • 45849130229 scopus 로고    scopus 로고
    • Serum zinc and albumin levels in pulmonary tuberculosis patients with and without HIV
    • Ramakrishnan K, Shenbagarathai R, Kavitha K, et al. Serum zinc and albumin levels in pulmonary tuberculosis patients with and without HIV. Jpn J Infect Dis 2008;61:202-4
    • (2008) Jpn J Infect Dis , vol.61 , pp. 202-204
    • Ramakrishnan, K.1    Shenbagarathai, R.2    Kavitha, K.3
  • 44
    • 34248545958 scopus 로고    scopus 로고
    • A computational model of the inhibition of Mycobacterium tuberculosis ATPase by a new drug candidate R207910
    • De Jonge MR, Koymans LHM, Guillemont JEG, et al. A computational model of the inhibition of Mycobacterium tuberculosis ATPase by a new drug candidate R207910. Proteins 2007;67:971-80
    • (2007) Proteins , vol.67 , pp. 971-980
    • De Jonge, M.R.1    Koymans, L.H.M.2    Guillemont, J.E.G.3
  • 45
    • 84860157680 scopus 로고    scopus 로고
    • New mutations in the mycobacterial ATP synthase: New insights into the binding of the diarylquinoline TMC207 to the ATP synthase C-ring structure
    • Segala E, Sougakoff W, Nevejans-Chauffour A, et al. New mutations in the mycobacterial ATP synthase: new insights into the binding of the diarylquinoline TMC207 to the ATP synthase C-ring structure. Antimicrob Agents Chemother 2012;56:2326-34
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 2326-2334
    • Segala, E.1    Sougakoff, W.2    Nevejans-Chauffour, A.3
  • 46
    • 33746916098 scopus 로고    scopus 로고
    • Genetic basis for natural and acquired resistance to the diarylquinoline R207910 in mycobacteria
    • Petrella S, Cambau E, Chauffour A, et al. Genetic basis for natural and acquired resistance to the diarylquinoline R207910 in mycobacteria. Antimicrob Agents Chemother 2006;50:2853-6
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 2853-2856
    • Petrella, S.1    Cambau, E.2    Chauffour, A.3
  • 47
    • 84861140844 scopus 로고    scopus 로고
    • Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: Long term outcome, tolerability, and effect on emergence of drug resistance
    • Diacon AH, Donald PR, Pym A, et al. Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long term outcome, tolerability, and effect on emergence of drug resistance. Antimicrob Agents Chemother 2012;56:3271-6
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 3271-3276
    • Diacon, A.H.1    Donald, P.R.2    Pym, A.3
  • 48
    • 84898619017 scopus 로고    scopus 로고
    • Cross-resistance between clofazimine and bedaquiline through upregulation of MmpL5 in Mycobacterium tuberculosis
    • Hartkoorn RC, Uplekar S, Cole ST. Cross-resistance between clofazimine and bedaquiline through upregulation of MmpL5 in Mycobacterium tuberculosis. Antimicrob Agents Chemother 2014;58:2979-81
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 2979-2981
    • Hartkoorn, R.C.1    Uplekar, S.2    Cole, S.T.3
  • 49
    • 84891543452 scopus 로고    scopus 로고
    • Efflux inhibition with verapamil potentiates bedaquiline in Mycobacterium tuberculosis
    • Gupta S, Cohen KA, Winglee K, et al. Efflux inhibition with verapamil potentiates bedaquiline in Mycobacterium tuberculosis. Antimicrob Agents Chemother 2014;58:574-6
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 574-576
    • Gupta, S.1    Cohen, K.A.2    Winglee, K.3
  • 50
    • 84859753546 scopus 로고    scopus 로고
    • Safety, tolerability, and pharmacokinetic interactions of the antituberculous agent TMC207 (bedaquiline) with efavirenz in healthy volunteers: AIDS clinical trials group study A5267
    • Dooley KE, Park JG, Swindells S, et al. Safety, tolerability, and pharmacokinetic interactions of the antituberculous agent TMC207 (bedaquiline) with efavirenz in healthy volunteers: AIDS Clinical Trials Group Study A5267. J Acquir Immune Defic Syndr 2012;59:455-62
    • (2012) J Acquir Immune Defic Syndr , vol.59 , pp. 455-462
    • Dooley, K.E.1    Park, J.G.2    Swindells, S.3
  • 51
    • 84877861235 scopus 로고    scopus 로고
    • Model-based estimates of the effects of efavirenz on bedaquiline pharmacokinetics and suggested dose adjustments for patients coinfected with HIV and tuberculosis
    • Svensson EM, Aweeka F, Park JG, et al. Model-based estimates of the effects of efavirenz on bedaquiline pharmacokinetics and suggested dose adjustments for patients coinfected with HIV and tuberculosis. Antimicrob Agents Chemother 2013;57:2780-7
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 2780-2787
    • Svensson, E.M.1    Aweeka, F.2    Park, J.G.3
  • 53
    • 66649088576 scopus 로고    scopus 로고
    • Unorthodox approach to the development of a new antituberculosis therapy
    • Barry CE III. Unorthodox approach to the development of a new antituberculosis therapy. N Engl J Med 2009;360:2466-7
    • (2009) N Engl J Med , vol.360 , pp. 2466-2467
    • Barry, C.E.1
  • 54
    • 84884558821 scopus 로고    scopus 로고
    • Bedaquiline: A new drug approved for treatment of multidrugresistant tuberculosis
    • Deoghare S. Bedaquiline: A new drug approved for treatment of multidrugresistant tuberculosis. Indian J Pharmacol 2013;45:536-7
    • (2013) Indian J Pharmacol , vol.45 , pp. 536-537
    • Deoghare, S.1
  • 55
    • 84907377122 scopus 로고    scopus 로고
    • TMC207-C208 study group,multidrug-resistant tuberculosis and culture conversion with bedaquiline
    • Diacon AH, Pym A, Grobusch MP, et al. TMC207-C208 Study group. Multidrug-resistant tuberculosis and culture conversion with bedaquiline. N Engl J Med 2014;371:723-32
    • (2014) N Engl J Med , vol.371 , pp. 723-732
    • Diacon, A.H.1    Pym, A.2    Grobusch, M.P.3
  • 56
    • 84891942518 scopus 로고    scopus 로고
    • Bedaquiline in MDR/XDR-TB cases: First experience on compassionate use
    • Tiberi S, De Lorenzo S, Centis R, et al. Bedaquiline in MDR/XDR-TB cases: first experience on compassionate use. Eur Respir J 2014;43:289-92
    • (2014) Eur Respir J , vol.43 , pp. 289-292
    • Tiberi, S.1    De Lorenzo, S.2    Centis, R.3
  • 57
    • 84942207119 scopus 로고    scopus 로고
    • Treatment of patients with MDR-TB
    • [Last accessed 10 May 2015]
    • Treatment of patients with MDR-TB. Anti-infective drugs advisory committee meeting briefing document TMC207 (bedaquiline). Available from: www.fda. gov/downloads/AdvisoryCommittees/ CommitteesMeetingMaterials/Drugs/ Anti-InfectiveDrugsAdvisoryCommittee/ UCM329260.pdf [Last accessed 10 May 2015]
    • Anti-infective Drugs Advisory Committee Meeting Briefing Document TMC207 (Bedaquiline)
  • 58
    • 84892866241 scopus 로고    scopus 로고
    • Bedaquiline: A novel diarylquinoline for multidrug-resistant tuberculosis
    • Chahine EB, Karaoui LR, Mansour H. Bedaquiline: A novel diarylquinoline for multidrug-resistant tuberculosis. Ann Pharmacother 2014;48:107-15
    • (2014) Ann Pharmacother , vol.48 , pp. 107-115
    • Chahine, E.B.1    Karaoui, L.R.2    Mansour, H.3
  • 60
    • 84883789341 scopus 로고    scopus 로고
    • Rising to the challenge: New therapies for tuberculosis
    • Wong EB, Cohen KA, Bishai WR. Rising to the challenge: new therapies for tuberculosis. Trends Microbiol 2013;21:493-501
    • (2013) Trends Microbiol , vol.21 , pp. 493-501
    • Wong, E.B.1    Cohen, K.A.2    Bishai, W.R.3
  • 61
    • 84885749877 scopus 로고    scopus 로고
    • Pharmaceutical approval update
    • Goldenberg MM. Pharmaceutical approval update. PT 2013;38:150-2
    • (2013) PT , vol.38 , pp. 150-152
    • Goldenberg, M.M.1
  • 62
    • 84885362205 scopus 로고    scopus 로고
    • Bedaquiline: First FDAapproved tuberculosis drug in 40 years
    • Mahajan R. Bedaquiline: first FDAapproved tuberculosis drug in 40 years. Int J Appl Basic Med Res 2013;3:1-2
    • (2013) Int J Appl Basic Med Res , vol.3 , pp. 1-2
    • Mahajan, R.1
  • 63
    • 84942207120 scopus 로고    scopus 로고
    • FDA accelerated approval letter to Janssen Research and Development
    • Washington, DC,[Last accessed 10 May 2015]
    • Cox EM. FDA accelerated approval letter to Janssen Research and Development. Food and Drug Administration, Washington, DC, 2012. Available from: www.accessdata. fda.gov/drugsatfda-docs/ appletter/2012/204384Orig1s000ltr.pdf [Last accessed 10 May 2015]
    • (2012) Food and Drug Administration
    • Cox, E.M.1
  • 64
    • 84907302558 scopus 로고    scopus 로고
    • FDA approval of bedaquiline-the benefit-risk balance for drug-resistant tuberculosis
    • Cox E, Laessig K. FDA approval of bedaquiline-the benefit-risk balance for drug-resistant tuberculosis. N Engl J Med 2014;371:689-91
    • (2014) N Engl J Med , vol.371 , pp. 689-691
    • Cox, E.1    Laessig, K.2
  • 65
    • 66649090346 scopus 로고    scopus 로고
    • The diarylquinoline TMC207 for multidrug-resistant tuberculosis
    • Diacon AH, Pym A, Grobusch M, et al. The diarylquinoline TMC207 for multidrug-resistant tuberculosis. N Engl J Med 2009;360:2397-405
    • (2009) N Engl J Med , vol.360 , pp. 2397-2405
    • Diacon, A.H.1    Pym, A.2    Grobusch, M.3
  • 66
    • 84891918791 scopus 로고    scopus 로고
    • Extensively drug-resistant tuberculosis: Early access to bedaquiline for a UK patient
    • van Halsema C, Humphreys S, Bonington A. Extensively drug-resistant tuberculosis: early access to bedaquiline for a UK patient. Eur Respir J 2014;43:292-4
    • (2014) Eur Respir J , vol.43 , pp. 292-294
    • Van Halsema, C.1    Humphreys, S.2    Bonington, A.3
  • 67
    • 84908870550 scopus 로고    scopus 로고
    • Briefing Package: TMC207 (Bedaquiline) FDA,MD; November 28,[Last accessed 10 May 2015]
    • FDA. Briefing package: TMC207 (bedaquiline). Treatment of patients with MDR-TB. Anti-Infective Drugs Advisory Committee Meeting Silver Spring, MD; November 28, 2012. Available from: http://www.fda.gov/downloads/ advisorycommittees/ committeesmeetingmaterials/drugs/antiinfectivedrugsadvisorycommittee/ ucm329260.pdf [Last accessed 10 May 2015]
    • (2012) Treatment of Patients with MDR-TB. Anti-Infective Drugs Advisory Committee Meeting Silver Spring
  • 68
    • 84908877912 scopus 로고    scopus 로고
    • Bedaquiline: A novel antitubercular agent for the treatment of multidrug-resistant tuberculosis
    • Worley MV, Estrada SJ. Bedaquiline: A novel antitubercular agent for the treatment of multidrug-resistant tuberculosis. Pharmacotherapy 2014;34:1187-97
    • (2014) Pharmacotherapy , vol.34 , pp. 1187-1197
    • Worley, M.V.1    Estrada, S.J.2
  • 69
    • 79952422865 scopus 로고    scopus 로고
    • Sterilizing activity of second-line regimens containing TMC207 in a murine model of tuberculosis
    • Veziris N, Ibrahim M, Lounis N, et al. Sterilizing activity of second-line regimens containing TMC207 in a murine model of tuberculosis. PLoS ONE 2011;6:e17556
    • (2011) PLoS ONE , vol.6 , pp. e17556
    • Veziris, N.1    Ibrahim, M.2    Lounis, N.3
  • 70
    • 84866488944 scopus 로고    scopus 로고
    • New treatment options for multidrugresistant tuberculosis
    • Field SK, Fisher D, Jarand JM, et al. New treatment options for multidrugresistant tuberculosis. Ther Adv Respir Dis 2012;6:255-68
    • (2012) Ther Adv Respir Dis , vol.6 , pp. 255-268
    • Field, S.K.1    Fisher, D.2    Jarand, J.M.3
  • 71
    • 41149173349 scopus 로고    scopus 로고
    • Synthesis and antitubercular activity of 7-(R)-and 7-(S)-methyl-2-nitro-6-(S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazines, analogues of PA-824
    • Xiaojin Li, Ujjini H, Manjunatha UH, et al. Synthesis and antitubercular activity of 7-(R)-and 7-(S)-methyl-2-nitro-6-(S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazines, analogues of PA-824. Bioorg Med Chem Lett 2009;18:2256-62
    • (2009) Bioorg Med Chem Lett , vol.18 , pp. 2256-2262
    • Xiaojin, L.1    Ujjini, H.2    Manjunatha, U.H.3
  • 72
    • 0032508046 scopus 로고    scopus 로고
    • Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
    • Cole ST, Brosch R, Parkhill J, et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 1998;393:537-44
    • (1998) Nature , vol.393 , pp. 537-544
    • Cole, S.T.1    Brosch, R.2    Parkhill, J.3
  • 73
    • 33845323336 scopus 로고    scopus 로고
    • OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice
    • Matsumoto M, Hashizume H, Tomishige T, et al. OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice. PLoS Med 2006;3:e466
    • (2006) PLoS Med , vol.3 , pp. e466
    • Matsumoto, M.1    Hashizume, H.2    Tomishige, T.3
  • 74
    • 43249102891 scopus 로고    scopus 로고
    • No authors listed. OPC-67683
    • No authors listed. OPC-67683. Tuberculosis (Edinb) 2008;88:132-3
    • (2008) Tuberculosis (Edinb) , vol.88 , pp. 132-133
  • 75
    • 84905712035 scopus 로고    scopus 로고
    • Delamanid: A new armor in combating drug-resistant tuberculosis
    • Xavier AS, Lakshmanan M. Delamanid: A new armor in combating drug-resistant tuberculosis. J Pharmacol Pharmacother 2014;5:222-4
    • (2014) J Pharmacol Pharmacother , vol.5 , pp. 222-224
    • Xavier, A.S.1    Lakshmanan, M.2
  • 76
    • 80052393888 scopus 로고    scopus 로고
    • Nitroimidazoles for the treatment of TB: Past, present and future
    • Mukherjee T, Boshoff H. Nitroimidazoles for the treatment of TB: past, present and future. Future Med Chem 2011;3:1427-1454.76
    • (2011) Future Med Chem , vol.3 , pp. 1427-145476
    • Mukherjee, T.1    Boshoff, H.2
  • 77
    • 79958718650 scopus 로고    scopus 로고
    • Early bactericidal activity of delamanid (OPC-67683) in smearpositive pulmonary tuberculosis patients
    • Diacon AH, Dawson R, Hanekom M, et al. Early bactericidal activity of delamanid (OPC-67683) in smearpositive pulmonary tuberculosis patients. Int J Tuberc Lung Dis 2011;15:949-54
    • (2011) Int J Tuberc Lung Dis , vol.15 , pp. 949-954
    • Diacon, A.H.1    Dawson, R.2    Hanekom, M.3
  • 78
    • 84893119514 scopus 로고    scopus 로고
    • The early bactericidal activity of antituberculosis drugs
    • Diacon AH, Donald PR. The early bactericidal activity of antituberculosis drugs. Expert Rev Anti Infect Ther 2014;12:223-37
    • (2014) Expert Rev Anti Infect Ther , vol.12 , pp. 223-237
    • Diacon, A.H.1    Donald, P.R.2
  • 79
    • 50649089808 scopus 로고    scopus 로고
    • The early bactericidal activity of anti-tuberculosis drugs: A literature review
    • Donald PR, Diacon AH. The early bactericidal activity of anti-tuberculosis drugs: A literature review. Tuberculosis (Edinb) 2008;88(Suppl 1):S75-83
    • (2008) Tuberculosis (Edinb , vol.88 , pp. S75-83
    • Donald, P.R.1    Diacon, A.H.2
  • 80
    • 84942207121 scopus 로고    scopus 로고
    • European medicines agency
    • [Last accessed 10 May 2015]
    • European Medicines Agency. Delamanid assessment report 2013. Available from: www.ema.europa.eu/ema/index.jsp? curl=pages/medicines/human/ medicines/002552/human-med-001699. jsp&mid=WC0b01ac058001d124 [Last accessed 10 May 2015]
    • (2013) Delamanid Assessment Report
  • 81
    • 84942207122 scopus 로고    scopus 로고
    • European medicines agency
    • [Last accessed May 2015]
    • European Medicines Agency. Delamanid (Deltyba): summary of product characteristics. 2014. Available from: http://ec.europa.eu/health/documents/ community-register/2014/ 20140428126881/anx-126881-en.pdf [Last accessed May 2015]
    • (2014) Delamanid (Deltyba): Summary of Product Characteristics
  • 82
    • 84910092131 scopus 로고    scopus 로고
    • Delamanid does not inhibit or induce cytochrome p450 enzymes in vitro
    • Shimokawa Y, Sasahara K, Yoda N, et al. Delamanid does not inhibit or induce cytochrome p450 enzymes in vitro. Biol Pharm Bull 2014;37:1727-35
    • (2014) Biol Pharm Bull , vol.37 , pp. 1727-1735
    • Shimokawa, Y.1    Sasahara, K.2    Yoda, N.3
  • 83
    • 84935101210 scopus 로고    scopus 로고
    • Delamanid: A review of its use in patients with multidrugresistant tuberculosis
    • Blair HA, Scott LJ. Delamanid: A review of its use in patients with multidrugresistant tuberculosis. Drugs 2015;75:91-100
    • (2015) Drugs , vol.75 , pp. 91-100
    • Blair, H.A.1    Scott, L.J.2
  • 84
    • 84861864703 scopus 로고    scopus 로고
    • Delamanid for multidrug-resistant pulmonary tuberculosis
    • Gler MT, Skripconoka V, Sanchez-Garavito E, et al. Delamanid for multidrug-resistant pulmonary tuberculosis. N Engl J Med 2012;366:2151-60
    • (2012) N Engl J Med , vol.366 , pp. 2151-2160
    • Gler, M.T.1    Skripconoka, V.2    Sanchez-Garavito, E.3
  • 85
    • 1642292440 scopus 로고    scopus 로고
    • Hypokalemia among patients receiving treatment for multidrug-resistant tuberculosis
    • Shin S, Furin J, Alcántara F. Hypokalemia among patients receiving treatment for multidrug-resistant tuberculosis. Chest 2004;125:974-80
    • (2004) Chest , vol.125 , pp. 974-980
    • Shin, S.1    Furin, J.2    Alcántara, F.3
  • 86
    • 84878776777 scopus 로고    scopus 로고
    • Delamanid improves outcomes and reduces mortality in multidrug-resistant tuberculosis
    • Skripconoka V, Danilovits M, Pehme L. Delamanid improves outcomes and reduces mortality in multidrug-resistant tuberculosis. Eur Respir J 2013;41:1393-400
    • (2013) Eur Respir J , vol.41 , pp. 1393-1400
    • Skripconoka, V.1    Danilovits, M.2    Pehme, L.3
  • 87
    • 84942207123 scopus 로고    scopus 로고
    • European medicines agency,public summary of opinion on orphan designation
    • 15 Nov ,[Last accessed 10 May 2015]
    • European medicines agency. Public summary of opinion on orphan designation. Media release. 15 Nov 2011. Available from: http://www.ema. europa.eu/docs/en-GB/document-library/ Orphan-designation/2009/10/ WC500006083.pdf [Last accessed 10 May 2015]
    • (2011) Media Release
  • 89
    • 84904039980 scopus 로고    scopus 로고
    • Delamanid: First global approval
    • Ryan NJ, Lo JH. Delamanid: first global approval. Drugs 2014;74:1041-5
    • (2014) Drugs , vol.74 , pp. 1041-1045
    • Ryan, N.J.1    Lo, J.H.2
  • 90
    • 84888370233 scopus 로고    scopus 로고
    • Clinical benefit of delamanid (OPC-67683) in the treatment of multidrug-resistant tuberculosis patients in China
    • Zhang Q, Liu Y, Tang S, et al. Clinical benefit of delamanid (OPC-67683) in the treatment of multidrug-resistant tuberculosis patients in China. Cell Biochem Biophys 2013;67:957-63
    • (2013) Cell Biochem Biophys , vol.67 , pp. 957-963
    • Zhang, Q.1    Liu, Y.2    Tang, S.3
  • 91
    • 84906890048 scopus 로고    scopus 로고
    • ERS/WHO Tuberculosis Consilium assistance with extensively drug-resistant tuberculosis management in a child: Case study of compassionate delamanid use
    • Esposito S, D'Ambrosio L, Tadolini M, et al. ERS/WHO Tuberculosis Consilium assistance with extensively drug-resistant tuberculosis management in a child: case study of compassionate delamanid use. Eur Respir J 2014;44:811-15
    • (2014) Eur Respir J , vol.44 , pp. 811-815
    • Esposito, S.1    D'Ambrosio, L.2    Tadolini, M.3
  • 94
    • 84896938981 scopus 로고    scopus 로고
    • Novel regimens identified in mice for treatment of latent tuberculosis infection in contacts of patients with multidrugresistant tuberculosis
    • Lanoix JP, Betoudji F, Nuermberger E. Novel regimens identified in mice for treatment of latent tuberculosis infection in contacts of patients with multidrugresistant tuberculosis. Antimicrob Agents Chemother 2014;58:2316-23221
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 2316-23221
    • Lanoix, J.P.1    Betoudji, F.2    Nuermberger, E.3
  • 98
    • 84924312173 scopus 로고    scopus 로고
    • Bactericidal activity of pyrazinamide and clofazimine alone and in combinations with pretomanid and bedaquiline
    • Diacon AH, Dawson R, von Groote-Bidlingmaier F, et al. Bactericidal activity of pyrazinamide and clofazimine alone and in combinations with pretomanid and bedaquiline. Am J Respir Crit Care Med 2015;191:943-53
    • (2015) Am J Respir Crit Care Med , vol.191 , pp. 943-953
    • Diacon, A.H.1    Dawson, R.2    Von Groote-Bidlingmaier, F.3
  • 99
    • 84929030774 scopus 로고    scopus 로고
    • Efficiency and safety of the combination of moxifloxacin, pretomanid (PA-824), and pyrazinamide during the first 8 weeks of antituberculosis treatment: A phase 2b, open-label, partly randomised trial in patients with drugsusceptible or drug-resistant pulmonary tuberculosis
    • Dawson R, Diacon AH, Everitt D, et al. Efficiency and safety of the combination of moxifloxacin, pretomanid (PA-824), and pyrazinamide during the first 8 weeks of antituberculosis treatment: A phase 2b, open-label, partly randomised trial in patients with drugsusceptible or drug-resistant pulmonary tuberculosis. Lancet 2015;385:1738-47
    • (2015) Lancet , vol.385 , pp. 1738-1747
    • Dawson, R.1    Diacon, A.H.2    Everitt, D.3


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