Evaluation of sterol transport from the endoplasmic reticulum to mitochondria using mitochondrially targeted bacterial sterol acyltransferase in Saccharomyces cerevisiae

Bioscience, Biotechnology and Biochemistry

Volumn 79, Issue 10, 2015, Pages 1608-1614

  Tian, Siqi ^a   Ohta, Akinori ^b   Horiuchi, Hiroyuki ^a   Fukuda, Ryouichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b CHUBU UNIVERSITY   (Japan)

Author keywords

Endoplasmic reticulum; Mitochondria; Saccharomyces cerevisiae; Sterol; Transport

Indexed keywords

BIOLOGICAL MEMBRANES; CELL MEMBRANES; ESTERS; MITOCHONDRIA; PROTEINS; YEAST;

ENDOPLASMIC RETICULUM; ENHANCED GREEN FLUORESCENT PROTEIN; MEMBRANE SPANNING DOMAINS; MICROSCOPIC OBSERVATIONS; SACCHAROMYCES CEREVISIAE MUTANT; STEROL; SUBCELLULAR FRACTIONATION; TRANSPORT;

ALCOHOLS;

ARE1 PROTEIN, S CEREVISIAE; ARE2 PROTEIN, S CEREVISIAE; BACTERIAL PROTEIN; CHAPERONE; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ESTER; ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; NUCLEAR PROTEIN; PET100 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; STEROL;

DEFICIENCY; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MITOCHONDRION; SACCHAROMYCES CEREVISIAE; TRANSPORT AT THE CELLULAR LEVEL;

BACTERIAL PROTEINS; BIOLOGICAL TRANSPORT; CHOLESTEROL ESTERS; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION, FUNGAL; GREEN FLUORESCENT PROTEINS; MITOCHONDRIA; MOLECULAR CHAPERONES; NUCLEAR PROTEINS; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; STEROL O-ACYLTRANSFERASE; STEROLS;

EID: 84942163276     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1080/09168451.2015.1058702     Document Type: Article

References (38)

1. Maxfield FR, Menon AK. Intracellular sterol transport and distribution. Curr. Opin. Cell Biol. 2006;18:379-385.
2. Zinser E, Sperka-Gottlieb CD, Fasch EV, Kohlwein SD, Paltauf F, Daum G. Phospholipid synthesis and lipid composition of subcellular membranes in the unicellular eukaryote Saccharomyces cerevisiae. J. Bacteriol. 1991;173:2026-2034.
3. Mesmin B, Antonny B, Drin G. Insights into the mechanisms of sterol transport between organelles. Cell. Mol. Life Sci. 2013;70: 3405-3421.
4. Daum G, Lees ND, Bard M, Dickson R. Biochemistry, cell biology and molecular biology of lipids of Saccharomyces cerevisiae. Yeast. 1998;14:1471-1510.
5. Kohlwein SD, Veenhuis M, van der Klei IJ. Lipid droplets and peroxisomes: key players in cellular lipid homeostasis or a matter of fat-store 'em up or burn 'em down. Genetics. 2013;193:1-50.
6. Kaplan MR, Simoni RD. Transport of cholesterol from the endoplasmic reticulum to the plasma membrane. J. Cell Biol. 1985;101:446-453.
7. Urbani L, Simoni RD. Cholesterol and vesicular stomatitis virus G protein take separate routes from the endoplasmic reticulum to the plasma membrane. J. Biol. Chem. 1990;265:1919-1923.
8. Heino S, Lusa S, Somerharju P, Ehnholm C, Olkkonen VM, Ikonen E. Dissecting the role of the Golgi complex and lipid rafts in biosynthetic transport of cholesterol to the cell surface. Proc. Nat. Acad. Sci. USA. 2000;97:8375-8380.
9. Baumann NA, Sullivan DP, Ohvo-Rekilä H, et al. Transport of newly synthesized sterol to the sterol-enriched plasma membrane occurs via nonvesicular equilibration. Biochemistiry. 2005;44: 5816-5826.
10. Holthuis JC, Menon AK. Lipid landscapes and pipelines in membrane homeostasis. Nature. 2014;510:48-57.
11. Tatsuta T, Scharwey M, Langer T. Mitochondrial lipid trafficking. Trends Cell. Biol. 2014;24:44-52.
12. Lev S. Nonvesicular lipid transfer from the endoplasmic reticulum. Cold Spring Harbor Perspect. Biol. 2012;4:a013300.
13. Wüstner D. Fluorescent sterols as tools in membrane biophysics and cell biology. Chem. Phys. Lipids. 2007;146:1-25.
14. Raychaudhuri S, Im YJ, Hurley JH, et al. Nonvesicular sterol movement from plasma membrane to ER requires oxysterolbinding protein-related proteins and phosphoinositides. J. Cell Biol. 2006; 173:107-119.
15. Horvath SE, Daum G. Lipids of mitochondria. Prog. Lipid Res. 2013;52:590-614.
16. Altmann K, Westermann B. Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. Mol. Biol. Cell. 2005;16:5410-5417.
17. Nikawa J, Kawabata M. PCR-and ligation-mediated synthesis of marker cassettes with long flanking homology regions for gene disruption in Saccharomyces cerevisiae. Nucleic Acids Res. 1998;26:860-861.
18. Kobayashi S, Mizuike A, Horiuchi H, Fukuda R, Ohta A. Mitochondrially-targeted bacterial phosphatidylethanolamine methyltransferase sustained phosphatidylcholine synthesis of a Saccharomyces cerevisiae Δpem1 Δpem2 double mutant without exogenous choline supply. Biochim. Biophys. Acta. 2014;1841: 1264-1271.
19. Gietz RD, Sugino A. New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene. 1988;74:527-534.
20. Fukuda R, Horiuchi H, Ohta A, Takagi M. The prosequence of Rhizopus niveus aspartic proteinase-I supports correct folding and secretion of its mature part in Saccharomyces cerevisiae. J. Biol. Chem. 1994;269:9556-9561.
21. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 1959;37:911-917.
22. Michalec Č. The nature of cholesterol esters in human blood serum. Biochim. Biophys. Acta. 1956;19:187-188.
23. Kobayashi S, Hirakawa K, Horiuchi H, Fukuda R, Ohta A. Phosphatidic acid and phosphoinositides facilitate liposome association of Yas3p and potentiate derepression of ARE1 (alkane-responsive element one)-mediated transcription control. Fungal Genet. Biol. 2013;61:100-110.
24. Zinser E, Daum G. Isolation and biochemical charakcterization of organelles from the yeast, Saccharomyces cerevisiae. Yeast. 1995;11:493-536.
25. Wuestehube LJ, Schekman RW. Reconstitution of transport from endoplasmic reticulum to Golgi complex using endoplasmic reticulum-enriched membrane fraction from yeast. Methods Enzymol. 1992;219:124-136.
26. Vipond R, Bricknell IR, Durant E, et al. Defined deletion mutants demonstrate that the major secreted toxins are not essential for the virulence of Aeromonas salmonicida. Infect. Immun. 1998;66:1990-1998.
27. Forsha D, Church C, Wazny P, Poyton RO. Structure and function of Pet100p, a molecular chaperone required for the assembly of cytochrome c oxidase in Saccharomyces cerevisiae. Biochem. Soc. Trans. 2001;29:436-441.
28. Church C, Goehring B, Forsha D, Wazny P, Poyton RO. Poyton RO. a role for Pet100p in the assembly of yeast cytochrome c oxidase: interaction with a subassembly that accumulates in a pet100 mutant. J. Biol. Chem. 2005;280:1854-1863.
29. Binns D, Januszewski T, Chen Y, et al. An intimate collaboration between peroxisomes and lipid bodies. J. Cell Biol. 2006;173:719-731.
30. Guo Y, Cordes KR, Farese RV, Walther TC. Lipid droplets at a glance. J. Cell Sci. 2009;122:749-752.
31. Buckley JT, Halasa LN, MacIntyre S. Purification and partial characterization of a bacterial phospholipid:cholesterol acyltransferase. J. Biol. Chem. 1982;257:3320-3325.
32. Kornmann B, Currie E, Collins SR, et al. An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science. 2009;325:477-481.
33. Nguyen TT, Lewandowska A, Choi JY, et al. Gem1 and ERMES do Not directly affect phosphatidylserine transport from ER to mitochondria or mitochondrial inheritance. Traffic. 2012;13:880-890.
34. Elbaz-Alon Y, Rosenfeld-Gur E, Shinder V, Futerman AH, Geiger T, Schuldiner M. A dynamic interface between vacuoles and mitochondria in yeast. Dev. Cell. 2014;30:95-102.
35. Hönscher C, Mari M, Auffarth K, et al. Cellular metabolism regulates contact sites between vacuoles and mitochondria. Dev. Cell. 2014;30:86-94.
36. Kim YJ, Hernandez ML, Balla T. Inositol lipid regulation of lipid transfer in specialized membrane domains. Trends Cell Biol. 2013;23:270-278.
37. Beh CT, McMaster CR, Kozminski KG, Menon AK. A detour for yeast oxysterol binding proteins. J. Biol. Chem. 2012;287:11481-11488.
38. Olkkonen VM, Li S. Oxysterol-binding proteins: sterol and phosphoinositide sensors coordinating transport, signaling and metabolism. Prog. Lipid Res. 2013;52:529-538.