Neuraminidase of influenza A virus binds lysosome-associated membrane proteins directly and induces lysosome rupture

Journal of Virology

Volumn 89, Issue 20, 2015, Pages 10347-10358

  Ju, Xiangwu ^a,b   Yan, Yiwu ^a,b   Liu, Qiang ^a,b   Li, Ning ^a,b   Sheng, Miaomiao ^a,b   Zhang, Lifang ^a,b   Li, Xiao ^c   Liang, Zhu ^a,b   Huang, Fengming ^a,b   Liu, Kangtai ^a,b   Zhao, Yan ^a,b   Zhang, Yanxu ^a,b   Zou, Zhen ^a,b   Du, Jianchao ^a,b   Zhong, Ying ^a,b   Zhou, Huandi ^a,b   Yang, Peng ^a,b   Lu, Huijun ^c   Tian, Mingyao ^c   Li, Dangsheng ^d   Zhang, Jianming ^a,b   Jin, Ningyi ^c   Jiang, Chengyu ^a,b,e   more..

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b TSINGHUA UNIVERSITY   (China)

^c BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^d Chinese Academy of Sciences   (China)

^e SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; PERAMIVIR; VIRUS SIALIDASE; ZANAMIVIR; CYCLOPENTANE DERIVATIVE; ENZYME INHIBITOR; GUANIDINE DERIVATIVE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN; PROTEIN BINDING; SIALIDASE; VIRUS PROTEIN;

ARTICLE; CATALYSIS; CELL DAMAGE; CELL DEATH; CELL RUPTURE; CONTROLLED STUDY; DEGLYCOSYLATION; EMBRYO; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INFLUENZA A (H1N1); INFLUENZA A (H5N1); INFLUENZA A VIRUS (H1N1); INFLUENZA A VIRUS (H5N1); LIFE CYCLE STAGE; LYSOSOME; MOLECULAR BIOLOGY; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN LOCALIZATION; VIRUS ATTACHMENT; VIRUS ENTRY; VIRUS LOAD; CELL MEMBRANE; CHEMISTRY; CYTOSOL; DRUG EFFECTS; ENZYMOLOGY; EPITHELIUM CELL; HYDROLYSIS; METABOLISM; PROTEIN DEGRADATION; RESPIRATORY TRACT MUCOSA; SPECIES DIFFERENCE; TUMOR CELL LINE; VIROLOGY;

CELL DEATH; CELL LINE, TUMOR; CELL MEMBRANE; CYCLOPENTANES; CYTOSOL; ENZYME INHIBITORS; EPITHELIAL CELLS; GUANIDINES; HUMANS; HYDROLYSIS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H5N1 SUBTYPE; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; LYSOSOMES; NEURAMINIDASE; PROTEIN BINDING; PROTEOLYSIS; RESPIRATORY MUCOSA; SPECIES SPECIFICITY; VIRAL PROTEINS; VIRUS INTERNALIZATION; ZANAMIVIR;

EID: 84942155321     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01411-15     Document Type: Article

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