Gender differences in the prevalence, severity, and composition of coronary artery disease in the young: A study of 1635 individuals undergoing coronary CT angiography fromthe prospective, multinational confirm registry

European Heart Journal Cardiovascular Imaging

Volumn 16, Issue 5, 2015, Pages 490-499

  Otaki, Yuka ^a   Gransar, Heidi ^a   Cheng, Victor Y ^a,b   Dey, Damini ^a,b   Labounty, Troy ^a   Lin, Fay Y ^c   Achenbach, Stephan ^d   Al Mallah, Mouaz ^e   Budoff, Matthew J ^f   Cademartiri, Filippo ^g,h   Callister, Tracy Q ⁱ   Chang, Hyuk Jae ^j   Chinnaiyan, Kavitha ^k   Chow, Benjamin J W ^l   Delago, Augustin ^m   Hadamitzky, Martin ⁿ   Hausleiter, Joerg ⁿ   Kaufmann, Philipp ^o   Maffei, Erica ^g,h   Raff, Gilbert ^k   Shaw, Leslee J ^p   Villines, Todd C ^q   Dunning, Allison ^c   Cury, Ricardo C ^r   Feuchtner, Gudrun ^s   Kim, Yong Jin ^t   Leipsic, Jonathon ^u   Berman, Daniel S ^a,b   Min, James K ^c   more..

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^d UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^e HENRY FORD HOSPITAL   (United States)

^f HARBOR UCLA MEDICAL CENTER   (United States)

^g Giovanni XXIII Hospital   (Italy)

^h ERASMUS MEDICAL CENTER   (Netherlands)

ⁱ Tennessee Heart and Vascular Institute   (United States)

^j Yonsei University Health System   (South Korea)

^k WILLIAM BEAUMONT HOSPITAL   (United States)

^l UNIVERSITY OF OTTAWA   (Canada)

^m Capitol Cardiology Associates   (United States)

ⁿ TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^o UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^p EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^q WALTER REED ARMY MEDICAL CENTER   (United States)

^r BAPTIST CARDIAC AND VASCULAR INSTITUTE   (United States)

^s INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^t Seoul National University Hospital   (South Korea)

^u UNIVERSITY OF BRITISH COLUMBIA   (Canada)

more..

Author keywords

Coronary artery disease; Coronary CT angiography; Coronary risk factors; Young adults

Indexed keywords

ADULT; ANGIOCARDIOGRAPHY; ARTICLE; CARDIOVASCULAR RISK; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; CONFIDENCE INTERVAL; CONTROLLED STUDY; CORONARY ARTERY ANOMALY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY DISEASE; CORONARY COMPUTERIZED TOMOGRAPHIC ANGIOGRAPHY; DIABETES MELLITUS; DISEASE SEVERITY; DYSLIPIDEMIA; FAMILY HISTORY; FEMALE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; REGISTER; SEX DIFFERENCE; SMOKING; CLINICAL TRIAL; CORONARY ANGIOGRAPHY; DIAGNOSTIC IMAGING; GENETIC PREDISPOSITION; GENETICS; MULTICENTER STUDY; RISK FACTOR; SEVERITY OF ILLNESS INDEX; X-RAY COMPUTED TOMOGRAPHY;

ADULT; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; PREVALENCE; PROSPECTIVE STUDIES; REGISTRIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SEX FACTORS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84942097466     PISSN: 20472404     EISSN: 20472412     Source Type: Journal    
DOI: 10.1093/ehjci/jeu281     Document Type: Article

References (24)

1. Arzamendi D, Benito B, Tizon-Marcos H, Flores J, Tanguay JF, Ly H et al. Increase in sudden death from coronary artery disease in young adults. Am Heart J 2011; 161:574-80.
2. Drory Y, Turetz Y, Hiss Y, Lev B, Fisman EZ, Pines A et al. Sudden unexpected death in persons less than 40 years of age. Am J Cardiol 1991;68:1388-92.
3. Rubin JB, Borden WB. Coronary heart disease in young adults. Curr Atheroscler Rep 2012;14:140-9.
4. Berenson GS, Srinivasan SR, BaoW, Newman WP 3rd, Tracy RE, WattigneyWA. Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study. N Engl J Med 1998;338:1650-6.
5. Enos WF Jr, Beyer JC, Holmes RH. Pathogenesis of coronary disease in American soldiers killed in Korea. J Am Med Assoc 1955;158:912-4.
6. EnosWF, Holmes RH, Beyer J. Coronary disease among United States soldiers killed in action in Korea; preliminary report. J Am Med Assoc 1953;152:1090-3.
7. McGill HC Jr, McMahan CA, Zieske AW, Sloop GD,Walcott JV, Troxclair DA et al. Associations of coronary heart disease risk factors with the intermediate lesion of atherosclerosis in youth. The Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group. Arterioscler Thromb Vasc Biol 2000;20:1998-2004.
8. McGill HC Jr, McMahan CA, Zieske AW, Tracy RE, Malcom GT, Herderick EE et al. Association of coronary heart disease risk factors with microscopic qualities of coronary atherosclerosis in youth. Circulation 2000;102:374-9.
9. McNamara JJ, MolotMA, Stremple JF, Cutting RT. Coronary artery disease in combat casualties in Vietnam. JAMA 1971;216:1185-7.
10. Tuzcu EM, Kapadia SR, Tutar E, Ziada KM, Hobbs RE, McCarthy PM et al. High prevalence of coronary atherosclerosis in asymptomatic teenagers and young adults: evidence from intravascular ultrasound. Circulation 2001;103:2705-10.
11. Virmani R, Robinowitz M, Geer JC, Breslin PP, Beyer JC, McAllister HA. Coronary artery atherosclerosis revisited in Korean war combat casualties. Arch Pathol Lab Med 1987;111:972-6.
12. Min JK, Dunning A, Lin FY, Achenbach S, Al-Mallah MH, Berman DS et al. Rationale and design of the CONFIRM (COronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter) Registry. J Cardiovasc Comput Tomogr 2011;5:84-92.
13. Budoff MJ, Dowe D, Jollis JG, Gitter M, Sutherland J, Halamert E et al. Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial. J Am Coll Cardiol 2008;52: 1724-32.
14. Meijboom WB, Meijs MF, Schuijf JD, Gitter M, Sutherland J, Halamert E et al. Diagnostic accuracy of 64-slice computed tomography coronary angiography: a prospective, multicenter, multivendor study. J Am Coll Cardiol 2008;52:2135-44.
15. Austen WG, Edwards JE, Frye RL, Gensini GG, Gott VL, Griffith LS et al. A reporting system on patients evaluated for coronary artery disease. Report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association. Circulation 1975;51:5-40.
16. Lin F, Shaw LJ, Berman DS, Callister TQ,Weinsaft JW,Wong FJ et al. Multidetector computed tomography coronary artery plaque predictors of stress-induced myocardial ischemia by SPECT. Atherosclerosis 2008;197:700-9.
17. Berenson GS, Wattigney WA, Tracy RE, Newman WP 3rd, Srinivasan SR, Webber LS et al. Atherosclerosis of the aorta and coronary arteries and cardiovascular risk factors in persons aged 6 to 30 years and studied at necropsy (The Bogalusa Heart Study). Am J Cardiol 1992;70:851-8.
18. McGillHCJr, McMahan CA. Determinants of atherosclerosis in the young. Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group. Am J Cardiol 1998;82:30T-6T.
19. Jousilahti P, Vartiainen E, Tuomilehto J, Puska P. Sex, age, cardiovascular risk factors, and coronary heart disease: a prospective follow-up study of 14 786 middle-aged men and women in Finland. Circulation 1999;99:1165-72.
20. Grady D, Rubin SM, Petitti DB, Fox CS, Black D, Ettinger B et al. Hormone therapy to prevent disease and prolong life in postmenopausal women. Ann Intern Med 1992; 117:1016-37.
21. Shahar E, Folsom AR, Salomaa VV, Stinson VL, McGovern PG, Shimakawa T et al. Relation of hormone-replacement therapy to measures of plasma fibrinolytic activity. Atherosclerosis Risk in Communities (ARIC) Study Investigators. Circulation 1996;93:1970-5.
22. Hoit BD, Gilpin EA, Henning H, Maisel AA, Dittrich H, Carlisle J et al. Myocardial infarction in young patients: an analysis by age subsets. Circulation 1986;74:712-21.
23. Zimmerman FH, Cameron A, Fisher LD,Ng G. Myocardial infarction in young adults: angiographic characterization, risk factors and prognosis (Coronary Artery Surgery Study Registry). J Am Coll Cardiol 1995;26:654-61.
24. Topol EJ, McCarthy J, Gabriel S, Moliterno DJ, Rogers WJ, Newby LK et al. Single nucleotide polymorphisms in multiple novel thrombospondin genes may be associated with familial premature myocardial infarction. Circulation 2001;104:2641-4.