메뉴 건너뛰기




Volumn 10, Issue 7, 2015, Pages

Improved methods to generate spheroid cultures from tumor cells, tumor cells & fibroblasts or tumor-fragments: microenvironment, microvesicles and MiRNA

Author keywords

[No Author keywords available]

Indexed keywords

AGAROSE; MICRORNA; BIOLOGICAL MARKER;

EID: 84942033507     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0133895     Document Type: Article
Times cited : (29)

References (45)
  • 1
    • 0015598413 scopus 로고
    • Repair of potentially lethal radiation damage in vitro and in vivo
    • Little JB, Hahn GM, Frindel E, Tubiana M. Repair of potentially lethal radiation damage in vitro and in vivo. Radiol 1973; 106: 689-694.
    • (1973) Radiol , vol.106 , pp. 689-694
    • Little, J.B.1    Hahn, G.M.2    Frindel, E.3    Tubiana, M.4
  • 2
    • 0017722296 scopus 로고
    • The effect of extreme hypoxia and glucose on repair of potentially lethal and sublethal radiation damage by mammalian cells
    • PMID: 877230
    • Koch CJ, Meneses J, Harris JW. The effect of extreme hypoxia and glucose on repair of potentially lethal and sublethal radiation damage by mammalian cells. Radiat Res 1977; 70: 542-551. PMID: 877230.
    • (1977) Radiat Res , vol.70 , pp. 542-551
    • Koch, C.J.1    Meneses, J.2    Harris, J.W.3
  • 3
    • 0024473604 scopus 로고
    • G1 events and regulation of cell proliferation
    • PMID: 2683075
    • Pardee AB. G1 events and regulation of cell proliferation. Science 1989; 246: 603-608. PMID: 2683075.
    • (1989) Science , vol.246 , pp. 603-608
    • Pardee, A.B.1
  • 4
    • 0024281372 scopus 로고
    • Cell and environmental interactions in tumor microregions: The multicellular spheroid model
    • PMID: 2451290
    • Sutherland RM. Cell and environmental interactions in tumor microregions: the multicellular spheroid model. Science 1988; 240: 177-184. PMID: 2451290.
    • (1988) Science , vol.240 , pp. 177-184
    • Sutherland, R.M.1
  • 5
    • 33845307724 scopus 로고    scopus 로고
    • Resistance of tumor cells to chemo- And radiotherapy modulated by the threedimensional architecture of solid tumors and spheroids
    • Durand RE, Olive PL. Resistance of tumor cells to chemo- And radiotherapy modulated by the threedimensional architecture of solid tumors and spheroids. Meth in Cell Biol 2001; 64: 211-233.
    • (2001) Meth in Cell Biol , vol.64 , pp. 211-233
    • Durand, R.E.1    Olive, P.L.2
  • 6
    • 0014885887 scopus 로고
    • A multi-component radiation survival curve using an in vitro tumour model
    • Sutherland RM, Inch WR, McCredie JA, Kruuv J. A multi-component radiation survival curve using an in vitro tumour model. Int J Radiat Biol 1970; 18: 491-495.
    • (1970) Int J Radiat Biol , vol.18 , pp. 491-495
    • Sutherland, R.M.1    Inch, W.R.2    McCredie, J.A.3    Kruuv, J.4
  • 7
    • 0016275208 scopus 로고
    • Selective chemotherapy of non-cycling cells in an in vitro tumor model
    • PMID: 4473266
    • Sutherland RM. Selective chemotherapy of non-cycling cells in an in vitro tumor model. Cancer Res. 1974; 34: 3501-3504. PMID: 4473266.
    • (1974) Cancer Res , vol.34 , pp. 3501-3504
    • Sutherland, R.M.1
  • 8
    • 0021191910 scopus 로고
    • Repair of fractionated radiation in plateau phase cultures of human tumor cells and human multicellular tumor spheroids
    • Weichselbaum RR, Little JB, Tomlinson K, Evans SM, Yuhas JM. Repair of fractionated radiation in plateau phase cultures of human tumor cells and human multicellular tumor spheroids. Radiotherapy and Oncology 1983; 2: 41-47.
    • (1983) Radiotherapy and Oncology , vol.2 , pp. 41-47
    • Weichselbaum, R.R.1    Little, J.B.2    Tomlinson, K.3    Evans, S.M.4    Yuhas, J.M.5
  • 9
    • 0024261272 scopus 로고
    • Relations between pH, oxygen partial pressure and growth in cultured cell spheroids
    • PMID: 3182108
    • Carlsson J, Acker H. Relations between pH, oxygen partial pressure and growth in cultured cell spheroids. Int J Cancer 1988; 42: 715-720. PMID: 3182108.
    • (1988) Int J Cancer , vol.42 , pp. 715-720
    • Carlsson, J.1    Acker, H.2
  • 10
    • 0021081179 scopus 로고
    • The radiation response of hypoxic cells in EMT6 spheroids in suspension culture does model data from EMT6 tumors
    • Franko AJ, Koch CJ. The radiation response of hypoxic cells in EMT6 spheroids in suspension culture does model data from EMT6 tumors. Radiat. Res. 1983; 96: 496-504.
    • (1983) Radiat. Res , vol.96 , pp. 496-504
    • Franko, A.J.1    Koch, C.J.2
  • 11
    • 66449096534 scopus 로고    scopus 로고
    • Organotypic glioma spheroids for screening of experimental therapies: How many spheroids and sections are required?
    • De Witt Hamer PC, Leenstar S, Van Norden CJF, Zwinderman AH. Organotypic glioma spheroids for screening of experimental therapies: how many spheroids and sections are required? Cyto 2009; 75A: 528-534.
    • (2009) Cyto , vol.75 A , pp. 528-534
    • De Witt Hamer, P.C.1    Leenstar, S.2    Van Norden, C.J.F.3    Zwinderman, A.H.4
  • 12
    • 40849139438 scopus 로고    scopus 로고
    • Co-culture of head and neck squamous cell carcinoma spheroids with autologous monocytes predicts prognosis
    • Kross KW, Heimdal JH, Olofsson J, Aarstad HJ. Co-culture of head and neck squamous cell carcinoma spheroids with autologous monocytes predicts prognosis. Scan J Immunol 2008; 67: 392-399.
    • (2008) Scan J Immunol , vol.67 , pp. 392-399
    • Kross, K.W.1    Heimdal, J.H.2    Olofsson, J.3    Aarstad, H.J.4
  • 13
    • 84902121858 scopus 로고    scopus 로고
    • Regulation of O2 consumption by the PI3K and mTOR pathways contributes to tumor hypoxia
    • Kelly CJ, Hussien K, Fokas E, Kannan P, Shipley RJ, Ashton TM, et al. Regulation of O2 consumption by the PI3K and mTOR pathways contributes to tumor hypoxia. Radioth Oncol 2014; 111: 72-80.
    • (2014) Radioth Oncol , vol.111 , pp. 72-80
    • Kelly, C.J.1    Hussien, K.2    Fokas, E.3    Kannan, P.4    Shipley, R.J.5    Ashton, T.M.6
  • 14
    • 0030032543 scopus 로고    scopus 로고
    • 2-nitroimidazole (EF5) binding predicts radiation sensitivity in individual 9L subcutaneous tumors
    • PMID: 8542599
    • Evans SM, Jenkins WT, Joiner B, Lord EM, Koch CJ. 2-nitroimidazole (EF5) binding predicts radiation sensitivity in individual 9L subcutaneous tumors. Cancer Res 1996; 56: 405-411. PMID: 8542599.
    • (1996) Cancer Res , vol.56 , pp. 405-411
    • Evans, S.M.1    Jenkins, W.T.2    Joiner, B.3    Lord, E.M.4    Koch, C.J.5
  • 16
    • 0021128745 scopus 로고
    • Binding of misonidazole to V79 spheroids and fragments of Dunning rat prostate and human colon carcinoma in vitro: Diffusion of oxygen and reactive metabolites
    • PMID: 6469756
    • Franko AJ, Koch CJ. Binding of misonidazole to V79 spheroids and fragments of Dunning rat prostate and human colon carcinoma in vitro: diffusion of oxygen and reactive metabolites. Int J Radiat Oncol Biol Phys 1984; 10: 1333-1337. PMID: 6469756.
    • (1984) Int J Radiat Oncol Biol Phys , vol.10 , pp. 1333-1337
    • Franko, A.J.1    Koch, C.J.2
  • 17
    • 0036048395 scopus 로고    scopus 로고
    • Measurement of absolute oxygen levels in cells and tissues using oxygen sensors and the 2-nitroimidazole EF5
    • Sen CK Packer L, (eds). San Diego. Academic Press
    • Koch CJ. Measurement of Absolute Oxygen Levels in Cells and Tissues using Oxygen Sensors and the 2-nitroimidazole EF5. In: Sen CK Packer L, (eds). Meth Enzymol-Antioxidants and Redox Cycling. San Diego. Academic Press, 2002, p 3-31.
    • (2002) Meth Enzymol-Antioxidants and Redox Cycling , pp. 3-31
    • Koch, C.J.1
  • 18
    • 0025392973 scopus 로고
    • Multicellular tumor spheroids from human gliomas maintained in organ culture
    • PMID: 2406382
    • Bjerkvig R, Tonnesen A, Laerum OD, Backlund E-O. Multicellular tumor spheroids from human gliomas maintained in organ culture. J Neurosurg 1990; 72: 463-475. PMID: 2406382.
    • (1990) J Neurosurg , vol.72 , pp. 463-475
    • Bjerkvig, R.1    Tonnesen, A.2    Laerum, O.D.3    Backlund, E.-O.4
  • 19
    • 33644559031 scopus 로고    scopus 로고
    • Identifying cancer stem cells in solid tumors: Case not proven
    • PMID: 16488984
    • Hill RP. Identifying cancer stem cells in solid tumors: case not proven. Cancer Res 2006; 66: 1891- 1986. PMID: 16488984.
    • (2006) Cancer Res , vol.66 , pp. 1891-1986
    • Hill, R.P.1
  • 20
    • 45849089879 scopus 로고    scopus 로고
    • Exploring the role of cancer stem cells in radioresistance
    • Baumann M, Krause M, Hill R. Exploring the role of cancer stem cells in radioresistance. Nature Rev Cancer 2008; 8: 545-554.
    • (2008) Nature Rev Cancer , vol.8 , pp. 545-554
    • Baumann, M.1    Krause, M.2    Hill, R.3
  • 21
    • 16544380146 scopus 로고    scopus 로고
    • The use of 3-D cultures for high-throughput screening: The multicellular spheroid model
    • Kunz-Schughart LA, Freyer JP, Horfstaedter F, Ebner R. The use of 3-D cultures for high-throughput screening: the multicellular spheroid model. J Biomolec Screen 2004; 9: 273-285.
    • (2004) J Biomolec Screen , vol.9 , pp. 273-285
    • Kunz-Schughart, L.A.1    Freyer, J.P.2    Horfstaedter, F.3    Ebner, R.4
  • 22
    • 84908275360 scopus 로고    scopus 로고
    • Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways
    • PMID: 25417103
    • Boelens MC, Wu TJ, Nabet BY, Qiu Y, Yoon T, Azzam DJ, et al. Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways. Cell 2014; 159: 499-513. doi:10.1016/j.cell.2014.09.051 PMID: 25417103.
    • (2014) Cell , vol.159 , pp. 499-513
    • Boelens, M.C.1    Wu, T.J.2    Nabet, B.Y.3    Qiu, Y.4    Yoon, T.5    Azzam, D.J.6
  • 23
  • 25
    • 0034807497 scopus 로고    scopus 로고
    • The Km for radiosensitization by oxygen is much greater than 3 mm of Hg and is further increased by elevated levels of cysteine
    • PMID: 11554850
    • Horan A-M, Koch CJ. The Km for radiosensitization by oxygen is much greater than 3 mm of Hg and is further increased by elevated levels of cysteine. Radiat. Res. 2001; 156: 388-398. PMID: 11554850.
    • (2001) Radiat. Res , vol.156 , pp. 388-398
    • Horan, A.-M.1    Koch, C.J.2
  • 26
    • 84915763634 scopus 로고    scopus 로고
    • Microvesicles as a biomarker for tumor progression versus treatment effect in radiation/temozolamide-treated glioblastoma patients
    • Koch CJ, Lustig RA, Yang X-Y, Jenkins WT, Wolf RL, Martinez-Lage M, et al. Microvesicles as a biomarker for tumor progression versus treatment effect in radiation/temozolamide-treated glioblastoma patients. Translat Onc 2014; 7: 752-758.
    • (2014) Translat Onc , vol.7 , pp. 752-758
    • Koch, C.J.1    Lustig, R.A.2    Yang, X.-Y.3    Jenkins, W.T.4    Wolf, R.L.5    Martinez-Lage, M.6
  • 28
    • 84874604550 scopus 로고    scopus 로고
    • FASTX
    • FASTX. FASTX-Toolkit. http://hannonlab.cshl.edu/fastx-toolkit/index.html.
    • FASTX-Toolkit
  • 31
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • R25.1-R25.10
    • Langmead B, Trapnell C, Pop M, Salzberg SL. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 2009; 10: R25.1-R25.10.
    • (2009) Genome Biol , vol.10
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 33
    • 79953310937 scopus 로고    scopus 로고
    • SHRiMP2: Sensitive yet practical short read mapping
    • PMID: 21278192
    • David M, Dzamba M, Lister D, Ilie L, Brudno M. SHRiMP2: sensitive yet practical short read Mapping. Bioinformatics 2011; 27: 1011-1012. doi:10.1093/bioinformatics/btr046 PMID: 21278192.
    • (2011) Bioinformatics , vol.27 , pp. 1011-1012
    • David, M.1    Dzamba, M.2    Lister, D.3    Ilie, L.4    Brudno, M.5
  • 34
    • 30344435264 scopus 로고    scopus 로고
    • Heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin potentiates the radiation response of tumor cells grown as monolayer cultures and spheroids by inducing apoptosis
    • PMID: 16367912
    • Machida H, Nakajima S, Shikano N, Nishio J, Okada S, Asayama M, et al. Heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin potentiates the radiation response of tumor cells grown as monolayer cultures and spheroids by inducing apoptosis. Cancer Sci 2005; 96: 911-917. PMID: 16367912.
    • (2005) Cancer Sci , vol.96 , pp. 911-917
    • Machida, H.1    Nakajima, S.2    Shikano, N.3    Nishio, J.4    Okada, S.5    Asayama, M.6
  • 35
    • 26944487557 scopus 로고    scopus 로고
    • Radiationenhanced vascular endothelial growth factor (VEGF) secretion in glioblastoma cell lines-A clue to radioresistance
    • Havinga KF, Stalpens LJA, van Bree C, Donker M, Verhoeff JJC, Rodermond HM, et al. Radiationenhanced vascular endothelial growth factor (VEGF) secretion in glioblastoma cell lines-a clue to radioresistance. J Neuro-Oncol 2005; 74: 99-103.
    • (2005) J Neuro-Oncol , vol.74 , pp. 99-103
    • Havinga, K.F.1    Stalpens, L.J.A.2    Van Bree, C.3    Donker, M.4    Verhoeff, J.J.C.5    Rodermond, H.M.6
  • 36
    • 0021382389 scopus 로고
    • A thin-film culturing technique allowing rapid gas-liquid equilibration (6 seconds) with no toxicity to mammalian cells
    • PMID: 6695057
    • Koch CJ. A thin-film culturing technique allowing rapid gas-liquid equilibration (6 seconds) with no toxicity to mammalian cells. Radiat Res 1984; 97: 434-442. PMID: 6695057.
    • (1984) Radiat Res , vol.97 , pp. 434-442
    • Koch, C.J.1
  • 37
    • 36849009670 scopus 로고    scopus 로고
    • Experimental anti-tumor therapy in 3-D: Spheroids-old hat or new challenge?
    • PMID: 18058370
    • Friedrich J, Ebner R, Kunz-Schughart LA. Experimental anti-tumor therapy in 3-D: Spheroids-old hat or new challenge? Int J radiat Biol 2007; 83: 849-871. PMID: 18058370.
    • (2007) Int J Radiat Biol , vol.83 , pp. 849-871
    • Friedrich, J.1    Ebner, R.2    Kunz-Schughart, L.A.3
  • 38
    • 77953066865 scopus 로고    scopus 로고
    • The microenvironment determines the breast cancer cells' phenotype: Organization of MCF7 cells in 3D cultures
    • PMID: 20529269
    • Krause S, Maffini MV, Soto AM, Sonnenschein C. The microenvironment determines the breast cancer cells' phenotype: organization of MCF7 cells in 3D cultures. BMC Cancer 2010; 10: 263. doi:10.1186/1471-2407-10-263 PMID: 20529269.
    • (2010) BMC Cancer , vol.10 , pp. 263
    • Krause, S.1    Maffini, M.V.2    Soto, A.M.3    Sonnenschein, C.4
  • 39
    • 84883810070 scopus 로고    scopus 로고
    • Application of concave microwells to pancreatic tumor spheroids enabling anticancer drug evaluation in a clinically relevant drug resistance model
    • PMID: 24039920
    • Yeon SE, No DY, Lee S-H, Nam SW, Oh I-H, Lee J, Kuh J. Application of concave microwells to pancreatic tumor spheroids enabling anticancer drug evaluation in a clinically relevant drug resistance model. PLOS One 2013; 8: e73345. doi:10.1371/journal.pone.0073345 PMID: 24039920.
    • (2013) PLOS One , vol.8 , pp. e73345
    • Yeon, S.E.1    No, D.Y.2    Lee, S.-H.3    Nam, S.W.4    Oh, I.-H.5    Lee, J.6    Kuh, J.7
  • 40
    • 0029922596 scopus 로고    scopus 로고
    • Mulicellular membranes as an in vitro model for extravascular diffusion in tumours
    • Cowan DSM, Hicks KO, Wilson WR. Mulicellular membranes as an in vitro model for extravascular diffusion in tumours. Brit J Cancer 1996; 74: S28-S31.
    • (1996) Brit J Cancer , vol.74 , pp. S28-S31
    • Cowan, D.S.M.1    Hicks, K.O.2    Wilson, W.R.3
  • 42
    • 44849127313 scopus 로고    scopus 로고
    • Importance of antibody concentration in the assessment of cellular hypoxia by flow cytometry: EF5 and Pimonidazole
    • PMID: 18494550
    • Koch CJ. Importance of antibody concentration in the assessment of cellular hypoxia by flow cytometry: EF5 and Pimonidazole. Radiat. Res. 2008; 169: 677-688. doi:10.1667/RR1305.1 PMID: 18494550.
    • (2008) Radiat. Res , vol.169 , pp. 677-688
    • Koch, C.J.1
  • 43
    • 0017808664 scopus 로고
    • Respiration of mammalian cells at low concentrations of oxygen I. Effect of hypoxic cell radiosensitizing drugs
    • Koch CJ, Biaglow JE. Respiration of mammalian cells at low concentrations of oxygen I. Effect of hypoxic cell radiosensitizing drugs. Brit. J. Cancer 1978; 37:163-167.
    • (1978) Brit. J. Cancer , vol.37 , pp. 163-167
    • Koch, C.J.1    Biaglow, J.E.2
  • 44
    • 42949149114 scopus 로고    scopus 로고
    • Glioblastomaderived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria
    • PMID: 18037961
    • Gunther HS, Schmidt NO, Phillips HS, Kemming D, Kharbanda S, Soriano R, et al. Glioblastomaderived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria. Oncogene 2008; 27: 2897-2909. PMID: 18037961.
    • (2008) Oncogene , vol.27 , pp. 2897-2909
    • Gunther, H.S.1    Schmidt, N.O.2    Phillips, H.S.3    Kemming, D.4    Kharbanda, S.5    Soriano, R.6
  • 45
    • 79551542410 scopus 로고    scopus 로고
    • In Vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection
    • PMID: 21266355
    • Marotta D, Karar J, Jenkins WT, Kumanova M, Jenkins KW, Tobias JW, et al. In Vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection. Cancer Res. 2011; 71: 779-789. doi:10.1158/0008-5472.CAN-10-3061 PMID: 21266355.
    • (2011) Cancer Res , vol.71 , pp. 779-789
    • Marotta, D.1    Karar, J.2    Jenkins, W.T.3    Kumanova, M.4    Jenkins, K.W.5    Tobias, J.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.