메뉴 건너뛰기




Volumn 408, Issue 1-2, 2015, Pages 103-113

The combined treatment with novel platinum(II) complex and anti-MUC1 increases apoptotic response in MDA-MB-231 breast cancer cells

Author keywords

Anti MUC1; Anticancer drugs; Apoptotic markers; Platinum complexes; Targeted therapy

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 8; CASPASE 9; CISPLATIN; LIPOCORTIN 5; MONOCLONAL ANTIBODY; MUCIN 1; PLATINUM DERIVATIVE; PROTEIN BAX; MUC1 PROTEIN, HUMAN; PLATINUM COMPLEX;

EID: 84941997664     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-015-2486-z     Document Type: Article
Times cited : (22)

References (31)
  • 1
    • 79954996475 scopus 로고    scopus 로고
    • Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors
    • COI: 1:CAS:528:DC%2BC3MXls1OltLo%3D, PID: 21346142
    • Zhou Y, Rajabi H, Kufe D (2011) Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors. Mol Pharmacol 79:886–893. doi:10.1124/mol.110.070797
    • (2011) Mol Pharmacol , vol.79 , pp. 886-893
    • Zhou, Y.1    Rajabi, H.2    Kufe, D.3
  • 3
    • 84874743726 scopus 로고    scopus 로고
    • MUC1-C oncoprotein as a target in breast cancer; activation of signaling pathways and therapeutic approaches
    • COI: 1:CAS:528:DC%2BC38XmvFCgs7o%3D, PID: 22580612
    • Kufe DW (2013) MUC1-C oncoprotein as a target in breast cancer; activation of signaling pathways and therapeutic approaches. Oncogene 32:1073–1081. doi:10.1038/onc.2012.158
    • (2013) Oncogene , vol.32 , pp. 1073-1081
    • Kufe, D.W.1
  • 4
    • 84878463053 scopus 로고    scopus 로고
    • MUC1 and metastatic cancer. Expression, function and therapeutic targeting
    • Horm TM, Schroeder JA (2013) MUC1 and metastatic cancer. Expression, function and therapeutic targeting. Cell Adhes Migr 7:187–198. doi:10.4161/cam.23131
    • (2013) Cell Adhes Migr , vol.7 , pp. 187-198
    • Horm, T.M.1    Schroeder, J.A.2
  • 8
    • 70349895167 scopus 로고    scopus 로고
    • MUC1 is a determinant of trastuzumab (Herceptin) resistance in breast cancer cells
    • COI: 1:CAS:528:DC%2BD1MXht1GmtbfN, PID: 19415485
    • Fessler SP, Wotkowicz MT, Mahanta SK, Bamdad C (2009) MUC1 is a determinant of trastuzumab (Herceptin) resistance in breast cancer cells. Breast Cancer Res Treat 118:113–124. doi:10.1007/s10549-009-0412-3
    • (2009) Breast Cancer Res Treat , vol.118 , pp. 113-124
    • Fessler, S.P.1    Wotkowicz, M.T.2    Mahanta, S.K.3    Bamdad, C.4
  • 9
    • 10744220453 scopus 로고    scopus 로고
    • Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents
    • COI: 1:CAS:528:DC%2BD2cXhvVOntb0%3D, PID: 14998492
    • Ren J, Agata N, Chen D, Li Y, Yu WH, Huang L, Raina D, Chen W, Kharbanda S, Kufe D (2004) Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents. Cancer Cell 5:163–175. doi:10.1007/s10549-009-0412-3
    • (2004) Cancer Cell , vol.5 , pp. 163-175
    • Ren, J.1    Agata, N.2    Chen, D.3    Li, Y.4    Yu, W.H.5    Huang, L.6    Raina, D.7    Chen, W.8    Kharbanda, S.9    Kufe, D.10
  • 10
    • 84862304215 scopus 로고    scopus 로고
    • The MUC1-C oncoprotein binds to the BH3 domain of the pro-apoptotic BAX protein and blocks BAX function
    • COI: 1:CAS:528:DC%2BC38Xos1CksrY%3D, PID: 22544745
    • Ahmad R, Alam M, Rajabi H, Kufe D (2012) The MUC1-C oncoprotein binds to the BH3 domain of the pro-apoptotic BAX protein and blocks BAX function. J Biol Chem 287:20866–20875. doi:10.1074/jbc.M112.357293
    • (2012) J Biol Chem , vol.287 , pp. 20866-20875
    • Ahmad, R.1    Alam, M.2    Rajabi, H.3    Kufe, D.4
  • 11
    • 51049090388 scopus 로고    scopus 로고
    • MUC1 oncoprotein blocks death receptor-mediated apoptosis by inhibiting recruitment of caspase-8
    • COI: 1:CAS:528:DC%2BD1cXpt1Squrw%3D, PID: 18676836
    • Agata N, Ahmad R, Kawano T, Raina D, Kharbanda S, Kufe D (2008) MUC1 oncoprotein blocks death receptor-mediated apoptosis by inhibiting recruitment of caspase-8. Cancer Res 68:6136–6144. doi:10.1158/0008-5472
    • (2008) Cancer Res , vol.68 , pp. 6136-6144
    • Agata, N.1    Ahmad, R.2    Kawano, T.3    Raina, D.4    Kharbanda, S.5    Kufe, D.6
  • 13
    • 74949136580 scopus 로고    scopus 로고
    • Immunotherapy of malignant disease with tumor antigen-specific monoclonal antibodies
    • COI: 1:CAS:528:DC%2BC3cXotFyn, PID: 20028761
    • Campoli M, Ferris R, Ferrone S, Wang X (2010) Immunotherapy of malignant disease with tumor antigen-specific monoclonal antibodies. Clin Cancer Res 16:11–20. doi:10.1158/1078-0432
    • (2010) Clin Cancer Res , vol.16 , pp. 11-20
    • Campoli, M.1    Ferris, R.2    Ferrone, S.3    Wang, X.4
  • 14
    • 85045781871 scopus 로고    scopus 로고
    • Monoclonal antibody-related drugs for cancer therapy
    • COI: 1:CAS:528:DC%2BC2cXks1Grsb0%3D, PID: 24270381
    • Li GN, Wang SP, Xue X, Qu XJ, Liu HP (2013) Monoclonal antibody-related drugs for cancer therapy. Drug Discov Ther 7:178–184. doi:10.5582/ddt.2013.v7.5.178
    • (2013) Drug Discov Ther , vol.7 , pp. 178-184
    • Li, G.N.1    Wang, S.P.2    Xue, X.3    Qu, X.J.4    Liu, H.P.5
  • 15
    • 1342343183 scopus 로고    scopus 로고
    • Aromatic analogues of DNA minor groove binders—synthesis and biological evaluation
    • PID: 14987838
    • Pućkowska A, Bielawski K, Bielawska A, Midura-Nowaczek K (2004) Aromatic analogues of DNA minor groove binders—synthesis and biological evaluation. Eur J Med Chem 39:99–105. doi:10.1016/j.ejmech.2003.11.005
    • (2004) Eur J Med Chem , vol.39 , pp. 99-105
    • Pućkowska, A.1    Bielawski, K.2    Bielawska, A.3    Midura-Nowaczek, K.4
  • 16
    • 33745663724 scopus 로고    scopus 로고
    • Novel amidine analogue of melphalan as a specific multifunctional inhibitor of growth and metabolism of human breast cancer cells
    • COI: 1:CAS:528:DC%2BD28XmsFSlsbY%3D, PID: 16730667
    • Bielawski K, Bielawska A, Sosnowska K, Miltyk W, Winnicka K, Pałka J (2006) Novel amidine analogue of melphalan as a specific multifunctional inhibitor of growth and metabolism of human breast cancer cells. Biochem Pharmacol 72:320–331. doi:10.1016/j.bcp.2006.04.028
    • (2006) Biochem Pharmacol , vol.72 , pp. 320-331
    • Bielawski, K.1    Bielawska, A.2    Sosnowska, K.3    Miltyk, W.4    Winnicka, K.5    Pałka, J.6
  • 17
    • 2642521875 scopus 로고    scopus 로고
    • Amidine analogue of chlorambucil is a stronger inhibitor of protein and DNA synthesis in breast cancer MCF-7 cells than is the parent drug
    • COI: 1:CAS:528:DC%2BD2cXkslWku7c%3D, PID: 15178351
    • Sienkiewicz P, Bielawski K, Bielawska A, Pałka J (2004) Amidine analogue of chlorambucil is a stronger inhibitor of protein and DNA synthesis in breast cancer MCF-7 cells than is the parent drug. Eur J Pharmacol 492:95–101. doi:10.1016/j.ejphar.2004.04.001
    • (2004) Eur J Pharmacol , vol.492 , pp. 95-101
    • Sienkiewicz, P.1    Bielawski, K.2    Bielawska, A.3    Pałka, J.4
  • 18
    • 77955056334 scopus 로고    scopus 로고
    • Cytotoxic efficacy of a novel dinuclear platinum(II) complex in human breast cancer cells
    • COI: 1:CAS:528:DC%2BC3cXptlWltrk%3D, PID: 20598681
    • Bielawska A, Popławska B, Surażyński A, Czarnomysy R, Bielawski K (2010) Cytotoxic efficacy of a novel dinuclear platinum(II) complex in human breast cancer cells. Eur J Pharmacol 643:34–41. doi:10.1016/j.ejphar.2010.06.022
    • (2010) Eur J Pharmacol , vol.643 , pp. 34-41
    • Bielawska, A.1    Popławska, B.2    Surażyński, A.3    Czarnomysy, R.4    Bielawski, K.5
  • 19
    • 84873802557 scopus 로고    scopus 로고
    • Cytotoxicity and induction of apoptosis of human breast cancer cells by novel platinum(II) complexes
    • COI: 1:CAS:528:DC%2BC3sXjsFCgt7o%3D, PID: 23376176
    • Bielawski K, Czarnomysy R, Muszyńska A, Bielawska A, Popławska B (2013) Cytotoxicity and induction of apoptosis of human breast cancer cells by novel platinum(II) complexes. Environ Toxicol Pharmacol 35:254–264. doi:10.1016/j.etap.2012.12.010
    • (2013) Environ Toxicol Pharmacol , vol.35 , pp. 254-264
    • Bielawski, K.1    Czarnomysy, R.2    Muszyńska, A.3    Bielawska, A.4    Popławska, B.5
  • 20
    • 84905178125 scopus 로고    scopus 로고
    • Cytotoxic efficacy of a novel dinuclear platinum(II) complex used with anti-MUC1 in human breast cancer cells
    • COI: 1:CAS:528:DC%2BC2cXksF2htrw%3D, PID: 24639126
    • Gornowicz A, Kałuża Z, Bielawska A, Gabryel-Porowska H, Czarnomysy R, Bielawski K (2014) Cytotoxic efficacy of a novel dinuclear platinum(II) complex used with anti-MUC1 in human breast cancer cells. Mol Cell Biochem 392:161–174. doi:10.1007/s11010-014-2018-2
    • (2014) Mol Cell Biochem , vol.392 , pp. 161-174
    • Gornowicz, A.1    Kałuża, Z.2    Bielawska, A.3    Gabryel-Porowska, H.4    Czarnomysy, R.5    Bielawski, K.6
  • 21
    • 84860992007 scopus 로고    scopus 로고
    • Choosing the right cell line for breast cancer research
    • PID: 21884641
    • Holliday DL, Speirs V (2011) Choosing the right cell line for breast cancer research. Breast Cancer Res 13:215. doi:10.1186/bcr2889
    • (2011) Breast Cancer Res , vol.13 , pp. 215
    • Holliday, D.L.1    Speirs, V.2
  • 22
    • 45349089531 scopus 로고    scopus 로고
    • Molecular machinery of mitochondrial fusion and fission
    • COI: 1:CAS:528:DC%2BD1cXls12mtb8%3D, PID: 18372247
    • Westermann B (2008) Molecular machinery of mitochondrial fusion and fission. J Biol Chem 283:13501–13505. doi:10.1074/jbc.R800011200
    • (2008) J Biol Chem , vol.283 , pp. 13501-13505
    • Westermann, B.1
  • 23
    • 41449093973 scopus 로고    scopus 로고
    • Differential effect of proIGF-II and IGF-II on resveratrol induced cell death by regulating survivin cellular localization and mitochondrial depolarization in breast cancer cells
    • COI: 1:CAS:528:DC%2BD1cXjs12ltLo%3D, PID: 18365867
    • Singh SK, Moretta D, Almaguel F, Wall NR, De Leon M, De Leon D (2007) Differential effect of proIGF-II and IGF-II on resveratrol induced cell death by regulating survivin cellular localization and mitochondrial depolarization in breast cancer cells. Growth Factors 25:363–372. doi:10.1080/08977190801886905
    • (2007) Growth Factors , vol.25 , pp. 363-372
    • Singh, S.K.1    Moretta, D.2    Almaguel, F.3    Wall, N.R.4    De Leon, M.5    De Leon, D.6
  • 24
    • 0033694728 scopus 로고    scopus 로고
    • Increased mitochondrial cytochrome c levels and mitochondrial hyperpolarization precede camptothecin-induced apoptosis in Jurkat cells
    • PID: 11139283
    • Sánchez-Alcázar JA, Ault JG, Khodjakov A, Schneider E (2000) Increased mitochondrial cytochrome c levels and mitochondrial hyperpolarization precede camptothecin-induced apoptosis in Jurkat cells. Cell Death Differ 7:1090–1100
    • (2000) Cell Death Differ , vol.7 , pp. 1090-1100
    • Sánchez-Alcázar, J.A.1    Ault, J.G.2    Khodjakov, A.3    Schneider, E.4
  • 25
    • 78649632254 scopus 로고    scopus 로고
    • Monoclonal antibody targeting MUC1 and increasing sensitivity to docetaxel as a novel strategy in treating human epithelial ovarian cancer
    • COI: 1:CAS:528:DC%2BC3cXhsVygsbvE, PID: 21075513
    • Wang L, Chen H, Liu F, Madigan MC, Power CA, Hao J, Patterson KI, Pourgholami MH, O’Brien PM, Perkins AC, Li Y (2011) Monoclonal antibody targeting MUC1 and increasing sensitivity to docetaxel as a novel strategy in treating human epithelial ovarian cancer. Cancer Lett 300:122–133. doi:10.1016/j.canlet.2010.09.013
    • (2011) Cancer Lett , vol.300 , pp. 122-133
    • Wang, L.1    Chen, H.2    Liu, F.3    Madigan, M.C.4    Power, C.A.5    Hao, J.6    Patterson, K.I.7    Pourgholami, M.H.8    O’Brien, P.M.9    Perkins, A.C.10    Li, Y.11
  • 26
    • 80052573203 scopus 로고    scopus 로고
    • Anti-MUC1 monoclonal antibody (C595) and docetaxel markedly reduce tumor burden and ascites, and prolong survival in an in vivo ovarian cancer model
    • COI: 1:CAS:528:DC%2BC3MXht1GisrzK, PID: 21931707
    • Wang L, Chen H, Pourgholami MH, Beretov J, Hao J, Chao H, Perkins AC, Kaersley JH, Li Y (2011) Anti-MUC1 monoclonal antibody (C595) and docetaxel markedly reduce tumor burden and ascites, and prolong survival in an in vivo ovarian cancer model. PLoS One 6:e24405. doi:10.1371/journal.pone.0024405
    • (2011) PLoS One , vol.6 , pp. 24405
    • Wang, L.1    Chen, H.2    Pourgholami, M.H.3    Beretov, J.4    Hao, J.5    Chao, H.6    Perkins, A.C.7    Kaersley, J.H.8    Li, Y.9
  • 27
    • 84902659459 scopus 로고    scopus 로고
    • Breast cancer immunotherapy: monoclonal antibodies and peptide-based vaccines
    • COI: 1:CAS:528:DC%2BC2cXpslyntb8%3D, PID: 24867051
    • Mohit E, Hashemi A, Allahyari M (2014) Breast cancer immunotherapy: monoclonal antibodies and peptide-based vaccines. Expert Rev Clin Immunol 10:927–961. doi:10.1586/1744666X.2014.916211
    • (2014) Expert Rev Clin Immunol , vol.10 , pp. 927-961
    • Mohit, E.1    Hashemi, A.2    Allahyari, M.3
  • 28
    • 2442693937 scopus 로고    scopus 로고
    • The MUC1 onco-protein activates the anti-apoptotic PI3K/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts
    • COI: 1:CAS:528:DC%2BD2cXjvV2gu7s%3D, PID: 14999001
    • Raina D, Kharbanda S, Kufe D (2004) The MUC1 onco-protein activates the anti-apoptotic PI3K/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts. J Biol Chem 279:20607–20612. doi:10.1074/jbc.M310538200
    • (2004) J Biol Chem , vol.279 , pp. 20607-20612
    • Raina, D.1    Kharbanda, S.2    Kufe, D.3
  • 29
    • 13844262819 scopus 로고    scopus 로고
    • Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response
    • COI: 1:CAS:528:DC%2BD2MXitFygu7k%3D, PID: 15710329
    • Wei X, Xu H, Kufe D (2005) Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response. Cancer Cell 7:167–178. doi:10.1016/j.ccr.2005.01.008
    • (2005) Cancer Cell , vol.7 , pp. 167-178
    • Wei, X.1    Xu, H.2    Kufe, D.3
  • 30
    • 33748055445 scopus 로고    scopus 로고
    • MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage
    • COI: 1:CAS:528:DC%2BD28XovVSqu7k%3D, PID: 16888623
    • Raina D, Ahmad R, Kumar S, Ren J, Yoshida K, Kharbanda S, Kufe D (2006) MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage. EMBO J 25:3774–3783. doi:10.1038/sj.emboj.7601263
    • (2006) EMBO J , vol.25 , pp. 3774-3783
    • Raina, D.1    Ahmad, R.2    Kumar, S.3    Ren, J.4    Yoshida, K.5    Kharbanda, S.6    Kufe, D.7
  • 31
    • 84873481897 scopus 로고    scopus 로고
    • Inhibition of the MUC1-C oncoprotein is synergistic with cytotoxic agents in the treatment of breast cancer cells
    • Uschida Y, Raina D, Kharbanda S, Kufe D (2013) Inhibition of the MUC1-C oncoprotein is synergistic with cytotoxic agents in the treatment of breast cancer cells. Cancer Biol Ther 14:127–134. doi:10.4161/cbt.22634
    • (2013) Cancer Biol Ther , vol.14 , pp. 127-134
    • Uschida, Y.1    Raina, D.2    Kharbanda, S.3    Kufe, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.