Evolution of a chimeric aspartate kinase for L-lysine production using a synthetic RNA device

Applied Microbiology and Biotechnology

Volumn 99, Issue 20, 2015, Pages 8527-8536

  Wang, Junming ^a   Gao, Dongfang ^a   Yu, Xiaoli ^a   Li, Wen ^a   Qi, Qingsheng ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Aspartate kinase; Escherichia coli; Evolution; L lysine; Riboswitch

Indexed keywords

AMINO ACIDS; BACTERIOLOGY; BIOCHEMISTRY; BIOSYNTHESIS; ENZYME INHIBITION; ESCHERICHIA COLI; METABOLITES; PLANTS (BOTANY); RNA;

ASPARTATES; EVOLUTION; L-LYSINE; L-LYSINE PRODUCTION; LYSINE BIOSYNTHESIS PATHWAY; RECOMBINANT ESCHERICHIA COLI; RIBOSWITCHES; THERMUS THERMOPHILUS;

ENZYMES;

ASPARTATE KINASE; LYSINE; RNA; THREONINE; HYBRID PROTEIN;

AMINO ACID; BIOACCUMULATION; CATALYSIS; ENZYME ACTIVITY; EQUIPMENT; INHIBITION; METABOLITE; MICROBIAL ACTIVITY; MUTATION; RNA; THERMOPHILIC BACTERIUM;

AMINO ACID SYNTHESIS; ARTICLE; BACILLUS SUBTILIS; CHIMERA; CITRIC ACID CYCLE; CONTROLLED STUDY; DNA REPLICATION ORIGIN; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ESCHERICHIA COLI; FEEDBACK SYSTEM; GENE CASSETTE; GENE INACTIVATION; IN VITRO STUDY; MOLECULAR CLONING; NEGATIVE FEEDBACK; NONHUMAN; PHENOTYPE; PROTEIN STRUCTURE; RANDOMIZED CONTROLLED TRIAL; RIBOSWITCH; THERMUS THERMOPHILUS; WILD TYPE; ENZYMOLOGY; GENETIC SCREENING; GENETICS; METABOLISM; PROCEDURES;

BACILLUS SUBTILIS; ESCHERICHIA COLI; THERMUS THERMOPHILUS;

ASPARTATE KINASE; BACILLUS SUBTILIS; ESCHERICHIA COLI; GENETIC TESTING; LYSINE; RECOMBINANT FUSION PROTEINS; THERMUS THERMOPHILUS;

EID: 84941993348     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-015-6615-0     Document Type: Article

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