Molecular characteristics of disease-causing and commensal staphylococcus lugdunensis isolates from 2003 to 2013 at a tertiary hospital in Taiwan

PLoS ONE

Volumn 10, Issue 8, 2015, Pages

  Yeh, Chun Fu ^a   Liu, Tsui Ping ^b   Cheng, Chun Wen ^a   Chang, Shih Cheng ^a,b   Lee, Ming Hsun ^a   Lu, Jang Jih ^a,b  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CLINDAMYCIN; COTRIMOXAZOLE; ERYTHROMYCIN; OXACILLIN; PENICILLIN DERIVATIVE; BACTERIAL DNA; BACTERIAL PROTEIN; HEMOLYSIN;

ADULT; AGR GENE; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; CATHETER INFECTION; COMMENSAL; COMMUNITY ACQUIRED INFECTION; CONTROLLED STUDY; FEMALE; GENE LOCUS; HUMAN; MAJOR CLINICAL STUDY; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; STAPHYLOCOCCUS LUGDUNENSIS; TAIWAN; AGED; CROSS INFECTION; DRUG EFFECTS; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MIDDLE AGED; MULTILOCUS SEQUENCE TYPING; MULTIPLEX POLYMERASE CHAIN REACTION; PATHOLOGY; PULSED FIELD GEL ELECTROPHORESIS; TERTIARY CARE CENTER; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BACTERIAL PROTEINS; CROSS INFECTION; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; FEMALE; HEMOLYSIN PROTEINS; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MULTILOCUS SEQUENCE TYPING; MULTIPLEX POLYMERASE CHAIN REACTION; OXACILLIN; STAPHYLOCOCCUS LUGDUNENSIS; TAIWAN; TERTIARY CARE CENTERS;

EID: 84941966216     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0134859     Document Type: Article

References (40)

1. Freney J, Brun Y, Bes M, Meugnier H, Grimont F, Grimont PA, et al. Staphylococcus lugdunensis sp. nov. and Staphylococcus schleiferi sp. nov., two species from human clinical specimens. Int J Syst Bacteriol. 1988; 38(2):168-172.
2. Choi SH, Chung JW, Lee EJ, Kim TH, Lee MS, Kang JM, et al. Incidence, characteristics, and outcomes of Staphylococcus lugdunensis bacteremia. J Clin Microbiol. 2010; 48(9):3346-3349. doi: 10. 1128/JCM.00609-10 PMID: 20592152
3. Shin JH, Jung HJ, Lee HR, Kim JH, Kim HR, Lee JN. Prevalence, identification, and antimicrobial susceptibility of Staphylococcus lugdunensis from various clinical specimens in Korea. Jpn J Infect Dis. 2007; 60(5):312. PMID: 17881876
4. Vandenesch F, Etienne J, Reverdy ME, Eykyn SJ. Endocarditis due to Staphylococcus lugdunensis: report of 11 cases and review. Clin Infect Dis. 1993; 17(5):871-876. PMID: 8286628
5. Frank KL, del Pozo JL, Patel R. From clinical microbiology to infection pathogenesis: how daring to be different works for Staphylococcus lugdunensis. Clin Microbiol Rev. 2008; 21(1):111-133. doi: 10. 1128/CMR.00036-07 PMID: 18202439
6. Hellbacher C, Tornqvist E, Soderquist B. Staphylococcus lugdunensis: clinical spectrum, antibiotic susceptibility, and phenotypic and genotypic patterns of 39 isolates. Clin Microbiol Infect. 2006; 12(1):43-49. PMID: 16460545
7. Lin J-F, Cheng C-W, Kuo A-J, Liu T-P, Yang C-C, Huang C-T, et al. Clinical experience and microbiologic characteristics of invasive Staphylococcus lugdunensis infection in a tertiary center in northern Taiwan. J Microbiol Immunol Infect. 2014 Feb 13. pii: S1684-1182(14)00002-4. doi: 10.1016/j.jmii. 2013.12.010
8. Herchline T, Ayers LW. Occurrence of Staphylococcus lugdunensis in consecutive clinical cultures and relationship of isolation to infection. J Clin Microbiol. 1991; 29(3):419-421. PMID: 2037657
9. Zinkernagel A, Zinkernagel M, Elzi M, Genoni M, Gubler J, Zbinden R, et al. Significance of Staphylococcus lugdunensis bacteremia: report of 28 cases and review of the literature. Infection. 2008; 36 (4):314-321. doi: 10.1007/s15010-008-7287-9 PMID: 18648747
10. Widerström M, Monsen T, Karlsson C, Wiström J. Molecular epidemiology of meticillin-resistant coagulase-negative staphylococci in a Swedish county hospital: evidence of intra-and interhospital clonal spread. J Hosp Infect. 2006; 64(2):177-183. PMID: 16911846
11. Kleiner E, Monk AB, Archer GL, Forbes BA. Clinical significance of Staphylococcus lugdunensis isolated from routine cultures. Clin Infect Dis. 2010; 51(7):801-803. doi: 10.1086/656280 PMID: 20726772
12. Wu A-B, Wang M-C, Tseng C-C, Lin W-H, Teng C-H, Huang A-H, et al. Clinical and microbiological characteristics of community-acquired Staphylococcus lugdunensis infections in Southern Taiwan. J Clin Microbiol. 2011; 49(8):3015-3018. doi: 10.1128/JCM.01138-11 PMID: 21697317
13. Yen TY, Sung YJ, Lin HC, Peng CT, Tien N, Hwang KP, et al. Emergence of oxacillin-resistant Staphylococcus lugdunensis carrying staphylococcal cassette chromosome mec type V in central Taiwan. J Microbiol Immunol Infect. 2014 Dec 11. pii: S1684-1182(14)00249-7. doi: 10.1016/j.jmii.2014.11.018
14. Jarraud S, Lyon GJ, Figueiredo AM, Lina G, Vandenesch F, Etienne J, et al. Exfoliatin-producing strains define a fourth agr specificity group in Staphylococcus aureus. J Bacteriol. 2000; 182(22):6517-6522. PMID: 11053400
15. Dufour P, Jarraud S, Vandenesch F, Greenland T, Novick RP, Bes M, et al. High genetic variability of the agr locus in Staphylococcus species. J Bacteriol. 2002; 184(4):1180-1186. PMID: 11807079
16. Jarraud S, Mougel C, Thioulouse J, Lina G, Meugnier H, Forey F, et al. Relationships between Staphylococcus aureus genetic background, virulence factors, agr groups (alleles), and human disease. Infect Immun. 2002; 70(2):631-641. PMID: 11796592
17. Rautenberg M, Joo H-S, Otto M, Peschel A. Neutrophil responses to staphylococcal pathogens and commensals via the formyl peptide receptor 2 relates to phenol-soluble modulin release and virulence. FASEB J. 2011; 25(4):1254-1263. doi: 10.1096/fj.10-175208 PMID: 21183593
18. Donvito B, Etienne J, Greenland T, Mouren C, Delorme V, Vandenesch F. Distribution of the synergistic haemolysin genes hld and slush with respect to agr in human staphylococci. FEMS Microbiol Lett. 1997; 151(2):139-144. PMID: 9228746
19. Tseng S-P, Lin Y-T, Tsai J-C, Hung W-C, Chen H-J, Chen P-F, et al. Genotypes and phenotypes of Staphylococcus lugdunensis isolates recovered from bacteremia. J Microbiol Immunol Infect. 2013 Dec 31. pii: S1684-1182(13)00229-6. doi: 10.1016/j.jmii.2013.11.006
20. Liu C, Shen D, Guo J, Wang K, Wang H, Yan Z, et al. Clinical and microbiological characterization of Staphylococcus lugdunensis isolates obtained from clinical specimens in a hospital in China. BMC Microbiol. 2012; 12(1): 168.
21. Souvenir D, Anderson DE, Palpant S, Mroch H, Askin S, Anderson J, et al. Blood cultures positive for coagulase-negative staphylococci: antisepsis, pseudobacteremia, and therapy of patients. J Clin Microbiol. 1998; 36(7): 1923-1926. PMID: 9650937
22. Fadel HJ, Patel R, Vetter EA, Baddour LM. Clinical significance of a single Staphylococcus lugdunensis-positive blood culture. J Clin Microbiol. 2011; 49(4):1697-1699. doi: 10.1128/JCM.02058-10 PMID: 21270222
23. Morrison MA, Hageman JC, Klevens RM. Case definition for community-associated methicillin-resistant Staphylococcus aureus. J Hosp Infect. 2006; 62(2):241.
24. Noguchi N, Goto K, Ro T, Narui K, Ko M, Nasu Y, et al. Using the tannase gene to rapidly and simply identify Staphylococcus lugdunensis. Diagn Microbiol Infect Dis. 2010; 66(1):120-123. doi: 10.1016/j. diagmicrobio.2009.03.028 PMID: 19446981
25. Szabados F, Woloszyn J, Richter C, Kaase M, Gatermann S. Identification of molecularly defined Staphylococcus aureus strains using matrix-assisted laser desorption/ionization time of flight mass spectrometry and the Biotyper 2.0 database. J Med Microbiol. 2010; 59(7):787-790.
26. Clinical and Laboratory StandardsInstitute. Performance standards for antimicrobial susceptibility testing; twenty-second informational supplement (CLSI Document M100-S22. 2012). Wayne, PA: Clinical and Laboratory Standards Institute; 2012
27. Kondo Y, Ito T, Ma XX, Watanabe S, Kreiswirth BN, Etienne J, et al. Combination of multiplex PCRs for staphylococcal cassette chromosome mec type assignment: rapid identification system for mec, ccr, and major differences in junkyard regions. Antimicrob Agents Chemother. 2007; 51(1):264-274. PMID: 17043114
28. McDougal LK, Steward CD, Killgore GE, Chaitram JM, McAllister SK, Tenover FC. Pulsed-field gel electrophoresis typing of oxacillin-resistant Staphylococcus aureus isolates from the United States: establishing a national database. J Clin Microbiol. 2003; 41(11):5113-5120. PMID: 14605147
29. Mediavilla JR, Chen L, Mathema B, Kreiswirth BN. Global epidemiology of community-associated methicillin resistant Staphylococcus aureus (CA-MRSA). Curr Opin Microbiol. 2012; 15(5):588-595. doi: 10.1016/j.mib.2012.08.003 PMID: 23044073
30. Kaito C, Saito Y, Nagano G, Ikuo M, Omae Y, Hanada Y, et al. Transcription and translation products of the cytolysin gene psm-mec on the mobile genetic element SCCmec regulate Staphylococcus aureus virulence. PLoS Path. 2011; 7(2):e1001267.
31. Kaito C, Omae Y, Matsumoto Y, Nagata M, Yamaguchi H, Aoto T, et al. A novel gene, fudoh, in the SCCmec region suppresses the colony spreading ability and virulence of Staphylococcus aureus. PLoS One. 2008; 3(12):e3921. doi: 10.1371/journal.pone.0003921 PMID: 19079549
32. Gonzalez BE, Rueda AM, Shelburne SA III, Musher DM, Hamill RJ, Hultén KG. Community-associated strains of methicillin-resistant Staphylococccus aureus as the cause of healthcare-associated infection. Infect Control Hosp Epidemiol. 2006; 27(10):1051-1056. PMID: 17006811
33. Brennan GI, Shore AC, Corcoran S, Tecklenborg S, Coleman DC, O'Connell B. Emergence of hospitaland community-associated panton-valentine leukocidin-positive methicillin-resistant Staphylococcus aureus genotype ST772-MRSA-V in Ireland and detailed investigation of an ST772-MRSA-V cluster in a neonatal intensive care unit. J Clin Microbiol. 2012; 50(3):841-847. doi: 10.1128/JCM.06354-11 PMID: 22189119
34. Seybold U, Kourbatova EV, Johnson JG, Halvosa SJ, Wang YF, King MD, et al. Emergence of community-associated methicillin-resistant Staphylococcus aureus USA300 genotype as a major cause of health care - associated blood stream infections. Clin Infect Dis. 2006; 42(5):647-656. PMID: 16447110
35. David M, Kearns A, Gossain S, Ganner M, Holmes A. Community-associated meticillin-resistant Staphylococcus aureus: nosocomial transmission in a neonatal unit. J Hosp Infect. 2006; 64(3):244-250. PMID: 16928408
36. Hebert G. Hemolysins and other characteristics that help differentiate and biotype Staphylococcus lugdunensis and Staphylococcus schleiferi. J Clin Microbiol. 1990; 28(11): 2425-2431. PMID: 2254418
37. Donvito B, Etienne J, Denoroy L, Greenland T, Benito Y, Vandenesch F. Synergistic hemolytic activity of Staphylococcus lugdunensis is mediated by three peptides encoded by a non-agr genetic locus. Infect Immun. 1997; 65(1):95-100. PMID: 8975897
38. Schwan WR, Langhorne MH, Ritchie HD, Stover CK. Loss of hemolysin expression in Staphylococcus aureus agr mutants correlates with selective survival during mixed infections in murine abscesses and wounds. FEMS Immunol Med Microbiol. 2003; 38(1):23-28. PMID: 12900051
39. Fowler VG, Sakoulas G, McIntyre LM, Meka VG, Arbeit RD, Cabell CH, et al. Persistent bacteremia due to methicillin-resistant Staphylococcus aureus infection is associated with agr dysfunction and lowlevel in vitro resistance to thrombin-induced platelet microbicidal protein. J Infect Dis. 2004; 190 (6):1140-1149. PMID: 15319865
40. Schweizer ML, Furuno JP, Sakoulas G, Johnson JK, Harris AD, Shardell MD, et al. Increased mortality with accessory gene regulator (agr) dysfunction in Staphylococcus aureus among bacteremic patients. Antimicrob Agents Chemother. 2011; 55(3):1082-1087. doi: 10.1128/AAC.00918-10 PMID: 21173172