Macrophage infiltration induces gastric cancer invasiveness by activating the β-catenin pathway

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Wu, Ming Hsun ^a   Lee, Wei Jiunn ^b   Hua, Kuo Tai ^c   Kuo, Min Liang ^c   Lin, Ming Tsan ^a,c  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CD68 ANTIGEN; CYCLIN D1; HERMES ANTIGEN; MATRILYSIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA; WNT PROTEIN;

ADULT; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CD44 GENE; CELL DENSITY; CONTROLLED STUDY; CYCLIN D1 GENE; CYTOKINE PRODUCTION; FEMALE; GAIN OF FUNCTION MUTATION; GASTRIC CANCER CELL LINE; GENE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; LOSS OF FUNCTION MUTATION; MACROPHAGE ACTIVATION; MACROPHAGE MIGRATION; MAJOR CLINICAL STUDY; MALE; METASTASIS POTENTIAL; MIDDLE AGED; PREDICTIVE VALUE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER; SURVIVAL PREDICTION; TUMOR ASSOCIATED LEUKOCYTE; TUMOR INVASION; TUMOR MICROENVIRONMENT; WESTERN BLOTTING; WNT SIGNALING PATHWAY; AGED; CELL NUCLEUS; IMMUNOLOGY; MACROPHAGE; METABOLISM; PATHOLOGY; STOMACH TUMOR; TUMOR CELL LINE;

AGED; BETA CATENIN; CELL LINE, TUMOR; CELL NUCLEUS; FEMALE; HUMANS; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; PROTEIN TRANSPORT; STOMACH NEOPLASMS;

EID: 84941963250     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0134122     Document Type: Article

References (37)

1. Ferlay J, Bray F, Pisani P, Parkin D. GLOBOCAN 2002: Cancer Incidence, Mortality and Prevalence Worldwide: IARC press 2004
2. Correa P. Helicobacter pylori infection and gastric cancer. Cancer Epidemiol Biomarkers Prev. 2003; 12(3):238s-41s. PMID: 12646518
3. Balkwill F. Tumor necrosis factor or tumor promoting factor? Cytokine Growth Factor Rev. 2002; 13 (2):135-41. PMID: 11900989
4. Bingle L, Brown NJ, Lewis CE. The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J Pathol. 2002; 196(3):254-65. Epub 2002/02/22. doi: 10. 1002/path.1027 [pii]. PMID: 11857487
5. Wu MH, Tsai YT, Hua KT, Chang KC, Kuo ML, Lin MT. Eicosapentaenoic acid and docosahexaenoic acid inhibit macrophage-induced gastric cancer cell migration by attenuating the expression of matrix metalloproteinase 10. J Nutr Biochem. 2012. Epub 2012/01/31. S0955-2863(11)00271-3 [pii] doi: 10. 1016/j.jnutbio.2011.09.004 PMID: 22285823
6. Taketo MM. Wnt signaling and gastrointestinal tumorigenesis in mouse models. Oncogene. 2006; 25 (57):7522-30. PMID: 17143296
7. Tsukamoto T, Yamamoto M, Ogasawara N, Ushijima T, Nomoto T, Fujita H, et al. beta-Catenin mutations and nuclear accumulation during progression of rat stomach adenocarcinomas. Cancer Sci. 2003; 94(12):1046-51. PMID: 14662019
8. Lowy AM, Clements WM, Bishop J, Kong L, Bonney T, Sisco K, et al. beta-Catenin/Wnt signaling regulates expression of the membrane type 3 matrix metalloproteinase in gastric cancer. Cancer Res. 2006; 66(9):4734-41. PMID: 16651426
9. Oshima H, Hioki K, Popivanova BK, Oguma K, Van Rooijen N, Ishikawa TO, et al. Prostaglandin E signaling and bacterial infection recruit tumor-promoting macrophages to mouse gastric tumors. Gastroenterology. 2011; 140(2):596-607 e7. Epub 2010/11/13. S0016-5085(10)01604-5 [pii] doi: 10.1053/j. gastro.2010.11.007 PMID: 21070778
10. Chen JJ, Lin YC, Yao PL, Yuan A, Chen HY, Shun CT, et al. Tumor-associated macrophages: the double- edged sword in cancer progression. J Clin Oncol. 2005; 23(5):953-64. PMID: 15598976
11. Lin MT, Chang CC, Lin BR, Yang HY, Chu CY, Wu MH, et al. Elevated expression of Cyr61 enhances peritoneal dissemination of gastric cancer cells through integrin alpha2beta1. J Biol Chem. 2007; 282 (47):34594-604. Epub 2007/10/02. M706600200 [pii] doi: 10.1074/jbc.M706600200 PMID: 17905740
12. Bikkavilli RK, Feigin ME, Malbon CC. p38 mitogen-activated protein kinase regulates canonical Wntbeta- catenin signaling by inactivation of GSK3beta. Journal of cell science. 2008; 121(Pt 21):3598-607. Epub 2008/10/24. doi: 10.1242/jcs.032854 PMID: 18946023
13. Cervenka I, Wolf J, Masek J, Krejci P, Wilcox WR, Kozubik A, et al. Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6. Molecular and cellular biology. 2011; 31(1):179-89. Epub 2010/10/27. doi: 10.1128/MCB.00550-10 PMID: 20974802; PubMed Central PMCID: PMC3019858
14. Condeelis J, Pollard JW. Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell. 2006; 124(2):263-6. Epub 2006/01/28. S0092-8674(06)00055-9 [pii] doi: 10.1016/j.cell. 2006.01.007 PMID: 16439202
15. Allavena P, Sica A, Solinas G, Porta C, Mantovani A. The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages. Crit Rev Oncol Hematol. 2008; 66(1):1-9. Epub 2007/10/05. S1040-8428(07)00162-X [pii] doi: 10.1016/j.critrevonc.2007.07.004 PMID: 17913510
16. Crumley AB, Going JJ, Hilmy M, Dutta S, Tannahill C, McKernan M, et al. Interrelationships between Tumor Proliferative Activity, Leucocyte and Macrophage Infiltration, Systemic Inflammatory Response, and Survival in Patients Selected for Potentially Curative Resection for Gastroesophageal Cancer. Ann Surg Oncol. 2011. Epub 2011/03/17. doi: 10.1245/s10434-011-1658-7 PMID: 21409484
17. Osinsky S, Bubnovskaya L, Ganusevich I, Kovelskaya A, Gumenyuk L, Olijnichenko G, et al. Hypoxia, tumour-associated macrophages, microvessel density, VEGF and matrix metalloproteinases in human gastric cancer: interaction and impact on survival. Clin Transl Oncol. 2011; 13(2):133-8. Epub 2011/02/18CLAT394 [pii]. PMID: 21324802. doi: 10.1007/s12094-011-0630-0
18. Ishigami S, Natsugoe S, Tokuda K, Nakajo A, Okumura H, Matsumoto M, et al. Tumor-associated macrophage (TAM) infiltration in gastric cancer. Anticancer Res. 2003; 23(5A):4079-83. Epub 2003/12/12. PMID: 14666722
19. Ohno S, Inagawa H, Dhar DK, Fujii T, Ueda S, Tachibana M, et al. The degree of macrophage infiltration into the cancer cell nest is a significant predictor of survival in gastric cancer patients. Anticancer Res. 2003; 23(6D):5015-22. Epub 2004/02/26. PMID: 14981961
20. Mizukami Y, Kono K, Kawaguchi Y, Akaike H, Kamimura K, Sugai H, et al. Localisation pattern of Foxp3+ regulatory T cells is associated with clinical behaviour in gastric cancer. Br J Cancer. 2008; 98 (1):148-53. Epub 2007/12/19. 6604149 [pii] doi: 10.1038/sj.bjc.6604149 PMID: 18087278; PubMed Central PMCID: PMC2359685
21. Ivanov DB, Philippova MP, Tkachuk VA. Structure and functions of classical cadherins. Biochemistry (Mosc). 2001; 66(10):1174-86. Epub 2001/12/12. BCM66101450 [pii]. PMID: 11736639
22. Bremnes RM, Veve R, Hirsch FR, Franklin WA. The E-cadherin cell-cell adhesion complex and lung cancer invasion, metastasis, and prognosis. Lung Cancer. 2002; 36(2):115-24. Epub 2002/04/17. S0169500201004718 [pii]. PMID: 11955645
23. Julkunen K, Makinen K, Karja V, Kosma VM, Eskelinen M. alpha-, beta- and chi-catenin expression in human pancreatic cancer. Anticancer Res. 2003; 23(6D):5043-7. Epub 2004/02/26. PMID: 14981965
24. Brabletz T, Jung A, Reu S, Porzner M, Hlubek F, Kunz-Schughart LA, et al. Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment. Proc Natl Acad Sci U S A. 2001; 98(18):10356-61. Epub 2001/08/30. doi: 10.1073/pnas.171610498 98/18/ 10356 [pii]. PMID: 11526241; PubMed Central PMCID: PMC56965
25. Brabletz T, Jung A, Spaderna S, Hlubek F, Kirchner T. Opinion: migrating cancer stem cells-an integrated concept of malignant tumour progression. Nat Rev Cancer. 2005; 5(9):744-9. Epub 2005/09/09. nrc1694 [pii] doi: 10.1038/nrc1694 PMID: 16148886
26. Fodde R, Brabletz T. Wnt/beta-catenin signaling in cancer stemness and malignant behavior. Curr Opin Cell Biol. 2007; 19(2):150-8. Epub 2007/02/20. S0955-0674(07)00021-X [pii] doi: 10.1016/j.ceb. 2007.02.007 PMID: 17306971
27. Fernando HC, Dekeratry D, Downie G, Finley D, Sullivan V, Sarkar S, et al. Feasibility of spray cryotherapy and balloon dilation for non-malignant strictures of the airway. Eur J Cardiothorac Surg. 2011; 40 (5):1177-80. Epub 2011/04/13. S1010-7940(11)00264-8 [pii] doi: 10.1016/j.ejcts.2011.02.062 PMID: 21482131
28. Yamamoto H, Kitadai Y, Oue N, Ohdan H, Yasui W, Kikuchi A. Laminin gamma2 mediates Wnt5ainduced invasion of gastric cancer cells. Gastroenterology. 2009; 137(1):242-52, 52 e1-6. Epub 2009/ 07/08. PMID: 19582886
29. Yamamoto H, Oue N, Sato A, Hasegawa Y, Matsubara A, Yasui W, et al. Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase. Oncogene. 2010; 29 (14):2036-46. Epub 2010/01/27. doi: 10.1038/onc.2009.496 PMID: 20101234
30. Bakker ER, Das AM, Helvensteijn W, Franken PF, Swagemakers S, van der Valk MA, et al. Wnt5a promotes human colon cancer cell migration and invasion but does not augment intestinal tumorigenesis in Apc1638N mice. Carcinogenesis. 2013; 34(11):2629-38. Epub 2013/06/15. doi: 10.1093/carcin/ bgt215 PMID: 23764752
31. Tetsu O, McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature. 1999; 398(6726):422-6. PMID: 10201372
32. van de Wetering M, Sancho E, Verweij C, de Lau W, Oving I, Hurlstone A, et al. The beta-catenin/TCF- 4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell. 2002; 111(2):241-50. PMID: 12408868
33. Peifer M, Polakis P. Wnt signaling in oncogenesis and embryogenesis-a look outside the nucleus. Science. 2000; 287(5458):1606-9. Epub 2000/03/25. PMID: 10733430
34. Morin PJ. beta-catenin signaling and cancer. Bioessays. 1999; 21(12):1021-30. Epub 1999/12/02. doi: 10.1002/(SICI)1521-1878(199912)22:1<1021::AID-BIES6>3.0.CO;2-P [pii]. PMID: 10580987
35. Dvory-Sobol H, Sagiv E, Liberman E, Kazanov D, Arber N. Suppression of gastric cancer cell growth by targeting the beta-catenin/T-cell factor pathway. Cancer. 2007; 109(2):188-97. Epub 2006/12/07. doi: 10.1002/cncr.22416 PMID: 17149756
36. Hayakawa K, Meng Y, Hiramatsu N, Kasai A, Yamauchi K, Yao J, et al. Priming of glomerular mesangial cells by activated macrophages causes blunted responses to proinflammatory stimuli. J Immunol. 2006; 176(4):2529-37. PMID: 16456014
37. Arnott CH, Scott KA, Moore RJ, Hewer A, Phillips DH, Parker P, et al. Tumour necrosis factor-alpha mediates tumour promotion via a PKC alpha- and AP-1-dependent pathway. Oncogene. 2002; 21 (31):4728-38. Epub 2002/07/09. doi: 10.1038/sj.onc.1205588 PMID: 12101411