Flux balance analysis with objective function defined by proteomics data-metabolism of mycobacterium tuberculosis exposed to mefloquine

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Montezano, Daniel ^a   Meek, Laura ^b   Gupta, Rashmi ^c   Bermudez, Luiz E ^b   Bermudez, José C M ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b OREGON STATE UNIVERSITY   (United States)

^c UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEFLOQUINE; ANTIMALARIAL AGENT; BACTERIAL PROTEIN;

ANALYTIC METHOD; ARTICLE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIUM CULTURE; BIOMASS; CELL METABOLISM; CONTROLLED STUDY; DRUG EXPOSURE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SPECIFICITY; FLUX BALANCE ANALYSIS; MASS SPECTROMETRY; METABOLIC FLUX ANALYSIS; METABOLOMICS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE METABOLISM; PROTEOMICS; STOICHIOMETRY; SYSTEM ANALYSIS; TRANSCRIPTOMICS; ALGORITHM; BIOLOGICAL MODEL; COMPUTER SIMULATION; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PROCEDURES;

ALGORITHMS; ANTIMALARIALS; BACTERIAL PROTEINS; COMPUTER SIMULATION; MEFLOQUINE; METABOLIC FLUX ANALYSIS; METABOLIC NETWORKS AND PATHWAYS; MODELS, BIOLOGICAL; MYCOBACTERIUM TUBERCULOSIS; PROTEOMICS;

EID: 84941915231     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0134014     Document Type: Article

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