Investigating the role of shape on the biological impact of gold nanoparticles in vitro

Nanomedicine

Volumn 10, Issue 17, 2015, Pages 2643-2657

  Tian, Furong ^a,b   Clift, Martin J D ^c   Casey, Alan ^b   Del Pino, Pablo ^d   Pelaz, Beatriz ^e   Conde, João ^f   Byrne, Hugh J ^b   Rothen Rutishauser, Barbara ^c   Estrada, Giovani ^a   De La Fuente, Jesús M ^g   Stoeger, Tobias ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b DUBLIN INSTITUTE OF TECHNOLOGY   (Ireland)

^c UNIVERSITY OF FRIBOURG   (Switzerland)

^d CIC BIOMAGUNE   (Spain)

^e PHILIPPS UNIVERSITY MARBURG   (Germany)

^f USA   (United States)

^g CSIC   (Spain)

Author keywords

biocompatibility; caspases; Cathepsin B; CD95 (APO 1 Fas); cell death; gold nanoparticles; lung epithelial cells; nanoparticle shape; nanotoxicology; reactive oxygen species

Indexed keywords

CASPASE; CATHEPSIN B; F ACTIN; FAS LIGAND; GOLD NANOPARTICLE; LACTATE DEHYDROGENASE; PROTEINASE; REACTIVE OXYGEN METABOLITE; CASP3 PROTEIN, HUMAN; CASP8 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE 3; CASPASE 8; CASPASE 9; CTSB PROTEIN, HUMAN; FAS ANTIGEN; FAS PROTEIN, HUMAN; GOLD; METAL NANOPARTICLE;

ADENOCARCINOMA CELL LINE; APOPTOSIS; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; BIOCOMPATIBILITY; CELL COUNT; CELL STRUCTURE; CELL SURFACE; CELL SURVIVAL; CELL VIABILITY; CELLULAR DISTRIBUTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME RELEASE; EPITHELIUM CELL; GEOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR INTERACTION; MOLECULAR WEIGHT; NANOTOXICOLOGY; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPARATION TECHNIQUE; SIGNAL TRANSDUCTION; SURFACE AREA; SURVIVAL RATE; THICKNESS; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL; CHEMISTRY; DRUG DELIVERY SYSTEM; DRUG EFFECTS; METABOLISM; SURFACE PROPERTY; TUMOR CELL LINE;

ANTIGENS, CD95; APOPTOSIS; CASPASE 3; CASPASE 8; CASPASE 9; CATHEPSIN B; CELL LINE, TUMOR; CELL SURVIVAL; DRUG DELIVERY SYSTEMS; EPITHELIAL CELLS; GOLD; HUMANS; METAL NANOPARTICLES; MICROSCOPY, ELECTRON, TRANSMISSION; PARTICLE SIZE; REACTIVE OXYGEN SPECIES; SPECTROPHOTOMETRY, ATOMIC; SURFACE PROPERTIES;

EID: 84941886516     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.15.103     Document Type: Article

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