메뉴 건너뛰기




Volumn 22, Issue 5, 2015, Pages e151-e157

Colchicine: New Insights to an Old Drug

Author keywords

colchicine; gout; inflammasome; mechanism of action; toxicity

Indexed keywords

COLCHICINE; CYTOCHROME P450 3A4; INFLAMMASOME; INTERLEUKIN 1BETA; URATE; ANTIGOUT AGENT; CARRIER PROTEIN; CYTOCHROME P450 3A; NLRP3 PROTEIN, HUMAN; URIC ACID;

EID: 84941880512     PISSN: 10752765     EISSN: 15363686     Source Type: Journal    
DOI: 10.1097/01.mjt.0000433937.07244.e1     Document Type: Article
Times cited : (32)

References (35)
  • 1
    • 33745226185 scopus 로고    scopus 로고
    • A concise history of gout and hyperuricemia and their treatment
    • Nuki G, Simkin PA. A concise history of gout and hyperuricemia and their treatment. Arthritis Res Ther. 2006;8(Suppl 1):S1.
    • (2006) Arthritis Res Ther , vol.8 , pp. S1
    • Nuki, G.1    Simkin, P.A.2
  • 2
    • 77954220989 scopus 로고    scopus 로고
    • Colchicine poisoning: The dark side of an ancient drug
    • Finkelstein Y, Aks SE, Hutson JR, et al. Colchicine poisoning: the dark side of an ancient drug. Clin Toxicol (Phila). 2010;48:407-414.
    • (2010) Clin Toxicol (Phila) , vol.48 , pp. 407-414
    • Finkelstein, Y.1    Aks, S.E.2    Hutson, J.R.3
  • 3
    • 51449124322 scopus 로고    scopus 로고
    • Colchicine: Its mechanism of action and efficacy in crystal-induced inflammation
    • Nuki G. Colchicine: its mechanism of action and efficacy in crystal-induced inflammation. Curr Rheumatol Rep. 2008;10:218-227.
    • (2008) Curr Rheumatol Rep , vol.10 , pp. 218-227
    • Nuki, G.1
  • 4
    • 0141998606 scopus 로고    scopus 로고
    • Molecular identification of a danger signal that alerts the immune system to dying cells
    • Shi Y, Evans JE, Rock KL. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature. 2003;425:516-521.
    • (2003) Nature , vol.425 , pp. 516-521
    • Shi, Y.1    Evans, J.E.2    Rock, K.L.3
  • 5
  • 6
    • 81055157096 scopus 로고    scopus 로고
    • The emerging role of interleukin-1b in autoinflammatory diseases
    • Lane T, Lachmann HJ. The emerging role of interleukin-1b in autoinflammatory diseases. Curr Allergy Asthma Rep. 2011;11:361-368.
    • (2011) Curr Allergy Asthma Rep , vol.11 , pp. 361-368
    • Lane, T.1    Lachmann, H.J.2
  • 7
    • 78650926948 scopus 로고    scopus 로고
    • Sodium overload and water influx activate the NALP3 inflammasome
    • Schorn C, Frey B, Lauber K, et al. Sodium overload and water influx activate the NALP3 inflammasome. J Biol Chem. 2011;286;35-41.
    • (2011) J Biol Chem , vol.286 , pp. 35-41
    • Schorn, C.1    Frey, B.2    Lauber, K.3
  • 8
    • 39549112322 scopus 로고    scopus 로고
    • Urate crystals, inflammation, and colchicine
    • McCarty DJ. Urate crystals, inflammation, and colchicine. Arthritis Rheum. 2008;58:S20-S24.
    • (2008) Arthritis Rheum , vol.58 , pp. S20-S24
    • McCarty, D.J.1
  • 9
    • 33749015997 scopus 로고    scopus 로고
    • Microtubule motors at the intersection of trafficking and transport
    • Caviston JP, Holzbaur ELF. Microtubule motors at the intersection of trafficking and transport. Trends Cell Biol. 2006;16:530-537.
    • (2006) Trends Cell Biol , vol.16 , pp. 530-537
    • Caviston, J.P.1    Holzbaur, E.L.F.2
  • 10
    • 0031736401 scopus 로고    scopus 로고
    • Does the lack of the P-glycoprotein efflux pump in neutrophils explain the efficacy of colchicine in familial Mediterranean fever and other inflammatory diseases?
    • Ben-Chetrit E, Levy M. Does the lack of the P-glycoprotein efflux pump in neutrophils explain the efficacy of colchicine in familial Mediterranean fever and other inflammatory diseases? Med Hypotheses. 1998;51:377-380.
    • (1998) Med Hypotheses , vol.51 , pp. 377-380
    • Ben-Chetrit, E.1    Levy, M.2
  • 11
    • 0029144844 scopus 로고
    • Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils
    • Cronstein BN, Molad Y, Reibman J, et al. Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils. J Clin Invest. 1995;96:994-1002.
    • (1995) J Clin Invest , vol.96 , pp. 994-1002
    • Cronstein, B.N.1    Molad, Y.2    Reibman, J.3
  • 12
    • 40949147771 scopus 로고    scopus 로고
    • Colchicine suppresses neutrophil superoxide production in a murine model of gouty arthritis: A rationale for use of low-dose colchicine
    • Chia EW, Grainger R, Harper JL. Colchicine suppresses neutrophil superoxide production in a murine model of gouty arthritis: a rationale for use of low-dose colchicine. Br J Pharmacol. 2008;153:1288-1295.
    • (2008) Br J Pharmacol , vol.153 , pp. 1288-1295
    • Chia, E.W.1    Grainger, R.2    Harper, J.L.3
  • 13
    • 0027360268 scopus 로고
    • Crystalinduced neutrophil activation. IV. Specific inhibition of tyrosine phosphorylation by colchicine
    • Roberge CJ, Gaudry M, de M-edicis R, et al. Crystalinduced neutrophil activation. IV. Specific inhibition of tyrosine phosphorylation by colchicine. J Clin Invest. 1993;92:1722-1729.
    • (1993) J Clin Invest , vol.92 , pp. 1722-1729
    • Roberge, C.J.1    Gaudry, M.2    De Medicis, R.3
  • 14
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • Martinon F, P-etrilli V, Mayor A, et al. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature. 2006;440:237-241.
    • (2006) Nature , vol.440 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3
  • 15
    • 0016378052 scopus 로고
    • Prophylactic colchicine therapy in familial Mediterranean fever. A controlled, doubleblind study
    • Goldstein RC, Schwabe AD. Prophylactic colchicine therapy in familial Mediterranean fever. A controlled, doubleblind study. Ann Intern Med. 1974;81:792-794.
    • (1974) Ann Intern Med , vol.81 , pp. 792-794
    • Goldstein, R.C.1    Schwabe, A.D.2
  • 16
    • 0016251282 scopus 로고
    • Colchicine therapy for familial mediterranean fever. A double-blind trial
    • Dinarello CA, Wolff SM, Goldfinger SE, et al. Colchicine therapy for familial mediterranean fever. A double-blind trial. N Engl J Med. 1974;291:934-937.
    • (1974) N Engl J Med , vol.291 , pp. 934-937
    • Dinarello, C.A.1    Wolff, S.M.2    Goldfinger, S.E.3
  • 17
    • 0016223474 scopus 로고
    • A controlled trial of colchicine in preventing attacks of familial mediterranean fever
    • Zemer D, Revach M, Pras M, et al. A controlled trial of colchicine in preventing attacks of familial mediterranean fever. N Engl J Med. 1974;291:932-934.
    • (1974) N Engl J Med , vol.291 , pp. 932-934
    • Zemer, D.1    Revach, M.2    Pras, M.3
  • 18
    • 79952425658 scopus 로고    scopus 로고
    • Anti-interleukin 1 treatment for patients with familial Mediterranean fever resistant to colchicine
    • Ozen S, Bilginer Y, Aktay Ayaz N, et al. Anti-interleukin 1 treatment for patients with familial Mediterranean fever resistant to colchicine. J Rheumatol. 2011;38:516-518.
    • (2011) J Rheumatol , vol.38 , pp. 516-518
    • Ozen, S.1    Bilginer, Y.2    Aktay Ayaz, N.3
  • 19
    • 77957675505 scopus 로고    scopus 로고
    • Interleukin-1 antagonism in acute gout: Is targeting a single cytokine the answer?
    • Neogi T. Interleukin-1 antagonism in acute gout: is targeting a single cytokine the answer? Arthritis Rheum. 2010;62: 2845-2849.
    • (2010) Arthritis Rheum , vol.62 , pp. 2845-2849
    • Neogi, T.1
  • 20
    • 0043182879 scopus 로고
    • Does colchicine work? the results of the first controlled study in acute gout
    • Ahern MJ, Reid C, Gordon TP, et al. Does colchicine work? The results of the first controlled study in acute gout. Aust N Z J Med. 1987;17:301-304.
    • (1987) Aust N Z J Med , vol.17 , pp. 301-304
    • Ahern, M.J.1    Reid, C.2    Gordon, T.P.3
  • 21
    • 33748608331 scopus 로고    scopus 로고
    • EULAR evidence based recommendations for gout. Part II: Management. Report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT)
    • Zhang W, Doherty M, Bardin T, et al. EULAR evidence based recommendations for gout. Part II: management. Report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis. 2006;65:1312-1324.
    • (2006) Ann Rheum Dis , vol.65 , pp. 1312-1324
    • Zhang, W.1    Doherty, M.2    Bardin, T.3
  • 22
    • 77950525312 scopus 로고    scopus 로고
    • High versus low dosing of oral colchicine for early acute gout flare: Twentyfour-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallel-group, dosecomparison colchicine study
    • TerkeltaubRA, FurstDE, BennettK, et al. High versus low dosing of oral colchicine for early acute gout flare: twentyfour-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallel-group, dosecomparison colchicine study. Arthritis Rheum. 2010;62: 1060-1068.
    • (2010) Arthritis Rheum , vol.62 , pp. 1060-1068
    • Terkeltaub, R.A.1    Furst, D.E.2    Bennett, K.3
  • 23
    • 25444510637 scopus 로고    scopus 로고
    • Colchicine as firstchoice therapy for recurrent pericarditis: Results of the CORE (COlchicine for REcurrent pericarditis) trial
    • Imazio M, Bobbio M, Cecchi E, et al. Colchicine as firstchoice therapy for recurrent pericarditis: results of the CORE (COlchicine for REcurrent pericarditis) trial. Arch Intern Med. 2005;165:1987-1991.
    • (2005) Arch Intern Med , vol.165 , pp. 1987-1991
    • Imazio, M.1    Bobbio, M.2    Cecchi, E.3
  • 24
    • 0035717365 scopus 로고    scopus 로고
    • Prevalence of ischaemic heart disease in patients with familial Mediterranean fever
    • Langevitz P, Livneh A, Neumann L, et al. Prevalence of ischaemic heart disease in patients with familial Mediterranean fever. Isr Med Assoc J. 2001;3:9-12.
    • (2001) Isr Med Assoc J , vol.3 , pp. 9-12
    • Langevitz, P.1    Livneh, A.2    Neumann, L.3
  • 25
    • 84863513850 scopus 로고    scopus 로고
    • Colchicine use is associated with decreased prevalence of myocardial infarction in patients with gout
    • Crittenden DB, Lehmann RA, Schneck L, et al. Colchicine use is associated with decreased prevalence of myocardial infarction in patients with gout. J Rheumatol. 2012;39: 1458-1464.
    • (2012) J Rheumatol , vol.39 , pp. 1458-1464
    • Crittenden, D.B.1    Lehmann, R.A.2    Schneck, L.3
  • 26
    • 84872678868 scopus 로고    scopus 로고
    • Low-dose colchicine for secondary prevention of cardiovascular disease
    • Nidorf SM, Eikelboom JW, Budgeon CA, et al. Low-dose colchicine for secondary prevention of cardiovascular disease. J Am Coll Cardiol. 2013;61:404-410.
    • (2013) J Am Coll Cardiol , vol.61 , pp. 404-410
    • Nidorf, S.M.1    Eikelboom, J.W.2    Budgeon, C.A.3
  • 27
    • 77958548721 scopus 로고    scopus 로고
    • COlchicine for the Prevention of the Post-pericardiotomy Syndrome (COPPS): A multicentre, randomized, double-blind, placeo-controlled trial
    • Imazio M, Trinchero R, Brucato A, et al. COlchicine for the Prevention of the Post-pericardiotomy Syndrome (COPPS): a multicentre, randomized, double-blind, placeo-controlled trial. Eur Heart J. 2010;31:2749-2754.
    • (2010) Eur Heart J , vol.31 , pp. 2749-2754
    • Imazio, M.1    Trinchero, R.2    Brucato, A.3
  • 28
    • 81855184470 scopus 로고    scopus 로고
    • Colchicine reduces postoperative atrial fibrillation: Results of the COlchicine for the Prevention of the Postpericardiotomy Syndrome (COPPS) atrial fibrillation substudy
    • Imazio M, Brucato A, Ferrazzi P, et al. Colchicine reduces postoperative atrial fibrillation: results of the COlchicine for the Prevention of the Postpericardiotomy Syndrome (COPPS) atrial fibrillation substudy. Circulation. 2011;124: 2290-2295.
    • (2011) Circulation , vol.124 , pp. 2290-2295
    • Imazio, M.1    Brucato, A.2    Ferrazzi, P.3
  • 29
    • 84879780646 scopus 로고    scopus 로고
    • Rationale and design of the colchicine for prevention of the postpericardiotomy syndrome and postoperative atrial fibrillation (COPPS-2 trial): A randomized, placebo-controlled, multicentre study on the use of colchicine for the primary prevention of the postpericardiotomy syndrome, postoperative effusions and postoperative atrial fibrillation
    • Imazio M, Belli R, Brucato A, et al. Rationale and design of the colchicine for prevention of the postpericardiotomy syndrome and postoperative atrial fibrillation (COPPS-2 trial): a randomized, placebo-controlled, multicentre study on the use of colchicine for the primary prevention of the postpericardiotomy syndrome, postoperative effusions and postoperative atrial fibrillation. Am Heart J. 2013; 166:13-19.
    • (2013) Am Heart J , vol.166 , pp. 13-19
    • Imazio, M.1    Belli, R.2    Brucato, A.3
  • 30
    • 20444481745 scopus 로고    scopus 로고
    • Inflammation of atrium after cardiac surgery is associated with inhomogeneity of atrial conduction and atrial fibrillation
    • Ishii Y, Schuessler RB, Gaynor SL, et al. Inflammation of atrium after cardiac surgery is associated with inhomogeneity of atrial conduction and atrial fibrillation. Circulation. 2005;111:2881-2888.
    • (2005) Circulation , vol.111 , pp. 2881-2888
    • Ishii, Y.1    Schuessler, R.B.2    Gaynor, S.L.3
  • 31
    • 77950547453 scopus 로고    scopus 로고
    • Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation
    • Rudolph V, Andrie RP, Rudolph TK, et al. Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation. Nat Med. 2010;16:470-474.
    • (2010) Nat Med , vol.16 , pp. 470-474
    • Rudolph, V.1    Andrie, R.P.2    Rudolph, T.K.3
  • 33
    • 0028327265 scopus 로고
    • Colchicine disposition in patients with familial Mediterranean fever with renal impairment
    • Ben-Chetrit E, Scherrmann JM, Zylber-Katz E, et al. Colchicine disposition in patients with familial Mediterranean fever with renal impairment. J Rheumatol. 1994;21:710-713.
    • (1994) J Rheumatol , vol.21 , pp. 710-713
    • Ben-Chetrit, E.1    Scherrmann, J.M.2    Zylber-Katz, E.3
  • 34
    • 79961101131 scopus 로고    scopus 로고
    • Novel evidence-based colchicine dose-reduction algorithm to predict and prevent colchicine toxicity in the presence of cytochrome P450 3A4/P-glycoprotein inhibitors
    • Terkeltaub RA, Furst DE, Digiacinto JL, et al. Novel evidence-based colchicine dose-reduction algorithm to predict and prevent colchicine toxicity in the presence of cytochrome P450 3A4/P-glycoprotein inhibitors. Arthritis Rheum. 2011;63:2226-2237.
    • (2011) Arthritis Rheum , vol.63 , pp. 2226-2237
    • Terkeltaub, R.A.1    Furst, D.E.2    Digiacinto, J.L.3
  • 35
    • 84867366942 scopus 로고    scopus 로고
    • Effects of grapefruit and seville orange juices on the pharmacokinetic properties of colchicine in healthy subjects
    • Wason S, Digiacinto JL, Davis MW. Effects of grapefruit and seville orange juices on the pharmacokinetic properties of colchicine in healthy subjects. Clin Ther. 2012;34: 2161-2173.
    • (2012) Clin Ther , vol.34 , pp. 2161-2173
    • Wason, S.1    Digiacinto, J.L.2    Davis, M.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.