Osteoprotective effect of combination therapy of low-dose oestradiol with G15, a specific antagonist of GPR30/GPER in ovariectomy-induced osteoporotic rats

Bioscience Reports

Volumn 35, Issue 4, 2015, Pages

  Kang, Wen Bo ^a   Cong, Yu ^b   Ru, Jiang Ying ^c   Ying, Si Qi ^d   Zhu, Ting ^e   Wang, Dong Sheng ^a   Liu, Xiao Wei ^a   Liu, Gang ^a   Zhao, Jian Ning ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

^c YANGZHOU UNIVERSITY   (China)

^d CHONGQING MEDICAL UNIVERSITY   (China)

^e FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Bone; G protein coupled oestrogen receptor 30 (GPR30 GPER); G15; Oestradiol (E2); Osteoporosis; Ovariectomy (OVX)

Indexed keywords

ALKALINE PHOSPHATASE; CALCIUM; ESTRADIOL; G PROTEIN COUPLED RECEPTOR 30; PHOSPHORUS; 1,3 BENZODIOXOLE DERIVATIVE; 4-(6-BROMO-1,3-BENZODIOXOL-5-YL)-3A,4,5,9B-3H-CYCLOPENTA(C)QUINOLINE; G PROTEIN COUPLED RECEPTOR; GPR30 PROTEIN, RAT; QUINOLINE DERIVATIVE;

ARTICLE; BIOMECHANICS; BODY WEIGHT; BONE DENSITY; BONE METABOLISM; BONE MINERAL; BONE STRESS; BONE STRUCTURE; BONE TURNOVER; CONTROLLED STUDY; CORTICAL BONE; ELASTICITY; EXTRACELLULAR MATRIX; FEMALE; LOW DRUG DOSE; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSTEOCLAST; OVARIECTOMY-INDUCED OSTEOPOROSIS; RAT; TRABECULAR BONE; UTERUS; YOUNG MODULUS; ANIMAL; ANTAGONISTS AND INHIBITORS; COMBINATION DRUG THERAPY; METABOLISM; OSTEOPOROSIS; OVARIECTOMY; PROCEDURES; SPRAGUE DAWLEY RAT;

ANIMALS; BENZODIOXOLES; DRUG THERAPY, COMBINATION; ESTRADIOL; FEMALE; OSTEOPOROSIS; OVARIECTOMY; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84941779205     PISSN: 01448463     EISSN: 15734935     Source Type: Journal    
DOI: 10.1042/BSR20150146     Document Type: Article

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