A radio-theranostic nanoparticle with high specific drug loading for cancer therapy and imaging

Journal of Controlled Release

Volumn 217, Issue , 2015, Pages 170-182

  Satterlee, Andrew B ^a,b   Yuan, Hong ^c   Huang, Leaf ^a,b  

^a UNC Hamner Institute for Drug Safety Sciences   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer; High specific drug loading; Nanoparticle; Theranostic

Indexed keywords

BALLOONS; CELL DEATH; DISEASES; ENCAPSULATION; NANOPARTICLES; RADIOISOTOPES; TUMORS;

ANTI-CANCER THERAPIES; APOPTOTIC CELL DEATH; CANCER; DOUBLE-STRANDED DNA BREAKS; DRUG LOADING; ENCAPSULATION EFFICIENCY; THERANOSTIC; TUMOR MICROENVIRONMENT;

LOADING;

CALCIUM PHOSPHATE; DOUBLE STRANDED DNA; LIPID CALCIUM PHOSPHATE; LUTETIUM 177; NANOCARRIER; SUCROSE; UNCLASSIFIED DRUG; LUTETIUM; NANOPARTICLE; RADIOISOTOPE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLADDER CANCER; CANCER INHIBITION; CANCER RADIOTHERAPY; CANCER SCINTISCANNING; CONTROLLED STUDY; DISTRIBUTION HALF-LIFE; DOUBLE STRANDED DNA BREAK; DRUG CLEARANCE; DRUG CYTOTOXICITY; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG MECHANISM; ELIMINATION HALF-LIFE; FEMALE; HUMAN; HUMAN CELL; MOUSE; MOUSE MODEL; NANOENCAPSULATION; NON SMALL CELL LUNG CANCER; NONHUMAN; PLASMA CLEARANCE; PRIORITY JOURNAL; RADIOISOTOPE THERAPY; RENAL CLEARANCE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SUCROSE GRADIENT; TRANSMISSION ELECTRON MICROSCOPY; TUMOR MICROENVIRONMENT; TUMOR MODEL; TUMOR VOLUME; TUMOR XENOGRAFT; WHOLE BODY IMAGING; WHOLE BODY SCINTISCANNING; 3T3 CELL LINE; ANIMAL; DNA DAMAGE; DRUG EFFECTS; METABOLISM; NEOPLASMS; NUDE MOUSE; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; THERANOSTIC NANOMEDICINE; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; CALCIUM PHOSPHATES; CELL LINE, TUMOR; DNA DAMAGE; FEMALE; HUMANS; LUTETIUM; MICE; MICE, NUDE; NANOPARTICLES; NEOPLASMS; NIH 3T3 CELLS; RADIOISOTOPES; THERANOSTIC NANOMEDICINE; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TUMOR MICROENVIRONMENT;

EID: 84941776941     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.08.048     Document Type: Article

References (34)

1. S.J. Goldsmith Radioimmunotherapy of lymphoma: Bexxar and Zevalin Semin. Nucl. Med. 40 2 2010 122 135
2. A.J. Grillo-Lopez Zevalin: the first radioimmunotherapy approved for the treatment of lymphoma Expert. Rev. Anticancer. Ther. 2 5 2002 485 493
3. L.E. van der Kolk, and et al. Complement activation plays a key role in the side-effects of rituximab treatment Br. J. Haematol. 115 4 2001 807 811
4. H.S. Kulkarni, and P.M. Kasi Rituximab and cytokine release syndrome Case Rep. Oncol. 5 1 2012 134 141
5. A.R. Rezvani, and D.G. Maloney Rituximab resistance Best Pract. Res. Clin. Haematol. 24 2 2011 203 216
6. J. Li, Y. Yang, and L. Huang Calcium phosphate nanoparticles with an asymmetric lipid bilayer coating for siRNA delivery to the tumor J. Control. Release 158 1 2012 108 114
7. Y. Zhang, and et al. Codelivery of VEGF siRNA and gemcitabine monophosphate in a single nanoparticle formulation for effective treatment of NSCLC Mol. Ther. 21 8 2013 1559 1569
8. Y. Zhang, and et al. Combinational delivery of c-myc siRNA and nucleoside analogs in a single, synthetic nanocarrier for targeted cancer therapy Biomaterials 34 33 2013 8459 8468
9. Y. Hu, and et al. A highly efficient synthetic vector: nonhydrodynamic delivery of DNA to hepatocyte nuclei in vivo ACS Nano 7 6 2013 5376 5384
10. R. Banerjee, and et al. Anisamide-targeted stealth liposomes: a potent carrier for targeting doxorubicin to human prostate cancer cells Int. J. Cancer 112 4 2004 693 700
11. Y.C. Tseng, and et al. Lipid-calcium phosphate nanoparticles for delivery to the lymphatic system and SPECT/CT imaging of lymph node metastases Biomaterials 35 16 2014 4688 4698
12. L. Miao, and et al. Nanoparticles with precise ratiometric Co-loading and Co-delivery of gemcitabine monophosphate and cisplatin for treatment of bladder cancer Adv. Funct. Mater. 24 42 2014 6601 6611
13. Y. Zhang, W.Y. Kim, and L. Huang Systemic delivery of gemcitabine triphosphate via LCP nanoparticles for NSCLC and pancreatic cancer therapy Biomaterials 34 13 2013 3447 3458
14. Y. Zhang, and et al. PKSolver: an add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel Comput. Methods Prog. Biomed. 99 3 2010 306 314
15. X.L.A.R.H. Byrne Rare earth and yttrium phosphate solubilities in aqueous solution Geochim. Cosmochim. Acta 61 8 1997 1625 1633
16. S. Zaichick, and et al. Accumulation of rare earth elements in human bone within the lifespan Metallomics 3 2 2011 186 194
17. J. Zhang, and et al. Synergistic anti-tumor effects of combined gemcitabine and cisplatin nanoparticles in a stroma-rich bladder carcinoma model J. Control. Release 182 2014 90 96
18. J.F. Torres-Roca, and et al. Prediction of radiation sensitivity using a gene expression classifier Cancer Res. 65 16 2005 7169 7176
19. M.G. Honig, and R.I. Hume Dil and diO: versatile fluorescent dyes for neuronal labelling and pathway tracing Trends Neurosci. 12 9 1989 333 335 340-1
20. S. Guo, and et al. Lipid-coated cisplatin nanoparticles induce neighboring effect and exhibit enhanced anticancer efficacy ACS Nano 7 11 2013 9896 9904
21. E.P. Rogakou, and et al. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 J. Biol. Chem. 273 10 1998 5858 5868
22. D.E. Ingber Can cancer be reversed by engineering the tumor microenvironment? Semin. Cancer Biol. 18 5 2008 356 364
23. P.P. Provenzano, and et al. Collagen reorganization at the tumor-stromal interface facilitates local invasion BMC Med. 4 1 2006 38
24. T.R. Cox, and J.T. Erler Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer Dis. Model. Mech. 4 2 2011 165 178
25. C.J. Baglole, and et al. More than structural cells, fibroblasts create and orchestrate the tumor microenvironment Immunol. Investig. 35 3-4 2006 297 325
26. A.K. Clark, and et al. A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer Biomaterials 34 20 2013 4777 4785
27. S. Sofou Radionuclide carriers for targeting of cancer Int. J. Nanomedicine 3 2 2008 181 199
28. E.M. Bednarczyk Radiopharmaceuticals in nuclear pharmacy and nuclear medicine, 3rd edition Ann. Pharmacother. 2012
29. J.R. Terman, and A. Kashina Post-translational modification and regulation of actin Curr. Opin. Cell Biol. 25 1 2013 30 38
30. N.O. Metreveli, and et al. UV-vis and FT-IR spectra of ultraviolet irradiated collagen in the presence of antioxidant ascorbic acid Ecotoxicol. Environ. Saf. 73 3 2010 448 455
31. C.A. Miles, and et al. Identification of an intermediate state in the helix-coil degradation of collagen by ultraviolet light J. Biol. Chem. 275 42 2000 33014 33020
32. E. Fujimori Ultraviolet light-induced change in collagen macromolecules Biopolymers 3 2 1965 115 119
33. A. Sionkowska, and A. Kaminska Thermal helix-coil transition in UV irradiated collagen from rat tail tendon Int. J. Biol. Macromol. 24 4 1999 337 340
34. U. Gluck, and et al. Regulation of adherens junction protein expression in growth-activated 3T3 cells and in regenerating liver Exp. Cell Res. 202 2 1992 477 486