AMP-regulated protein kinase activity in the hearts of mice treated with low- or high-fat diet measured using novel LC–MS method

Molecular and Cellular Biochemistry

Volumn 404, Issue 1-2, 2015, Pages 5-10

  Rybakowska, I M ^a   Slominska, E M ^a   Romaszko, P ^a   Olkowicz, M ^a,b   Kaletha, K ^a   Smolenski, R T ^a  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

^b POZNA UNIVERSITY OF LIFE SCIENCES   (Poland)

Author keywords

Adenosine deaminase; AMP deaminase; AMP regulated protein kinase; High fat diet

Indexed keywords

ADENOSINE DEAMINASE; ADENOSINE MONOPHOSPHATE DEAMINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUCOSE; NUCLEOTIDE; ADENOSINE PHOSPHATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ENZYME ACTIVITY; FEMALE; GLUCOSE BLOOD LEVEL; HEART; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID DIET; LOW FAT DIET; MASS FRAGMENTOGRAPHY; MOUSE; NONHUMAN; NUCLEOTIDE METABOLISM; PROTEIN PURIFICATION; ANIMAL; BIOSYNTHESIS; CARDIAC MUSCLE; ENZYMOLOGY; ISOLATION AND PURIFICATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; OBESITY; PATHOLOGY;

ADENOSINE MONOPHOSPHATE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CHROMATOGRAPHY, LIQUID; DIET, HIGH-FAT; MASS SPECTROMETRY; MICE; MYOCARDIUM; OBESITY;

EID: 84941743716     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-015-2360-z     Document Type: Article

References (13)

1. Hardie DG, Hawley SA, Scott JW (2006) AMP-activated protein kinase-development of the energy sensor concept. J Physiol 574:7–15
2. Hardie DG, Salt IP, Hawley SA, Davies SP (1999) AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge. Biochem J 338:717–722
3. Folmes CD, Wagg CS, Shen M, Clanachan AS, Tian R, Lopaschuk GD (2009) Suppression of 5′-AMP-activated protein kinase activity does not impair recovery of contractile function during reperfusion of ischemic hearts. Am J Physiol Heart Circ Physiol 297:H313–H321
4. Andersson U, Filipsson K, Abbott CR, Woods A, Smith K, Bloom SR, Carling D, Small CJ (2004) AMP-activated protein kinase plays a role in the control of food intake. J Biol Chem 279:12005–12008
5. Saltiel AR, Kahn CR (2001) Insulin signaling and the regulation of glucose and lipid metabolism. Nature 414:799–806
6. An D, Kewalramani G, Chan JK, Qi D, Ghosh S, Pulinilkunnil T, Abrahani A, Innis SM, Rodrigues B (2006) Metformin influences cardiomyocyte cell death by pathways that are dependent and independent of caspase-3. Diabetologia 49:2174–2184
7. Russell RR, Bergeron R, Shulman GI, Young LH (1999) Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR. Am J Physiol 277:H643–H649
8. Żydowo M (1976) Adenine compound in the heart. Int J Biochem 7:353–357
9. Smolenski RT, Suitters A, Yacoub MH (1992) Adenine nucleotide catabolism and adenosine formation in isolated human cardiomyocytes. J Mol Cell Cardiol 24:91–96
10. Baron SJ, Li J, Russell RR, Neumann D, Miller EJ, Tuerk R, Wallimann T, Hurley RL, Witters LA, Young LH (2005) Dual mechanisms regulating AMPK kinase action in the ischemic heart. Circ Res 96:337–345
11. Rybakowska I, Slominska EM, Romaszko P, Lipiński M, Żukowska P, Smolenski RT (2014) Activity of AMP-regulated protein kinase and AMP-deaminase in the heart of mice fed high fat diet. Nucleosides Nucleotides Nucleic Acids 33:347–352
12. Kochan Z, Smolenski RT, Yacoub MH, Seymour AL (1994) Nucleotide and adenosine metabolism in different cell types of human and rat heart. J Mol Cell Cardiol 26:1497–1503
13. Smolenski RT, Lachno DR, Ledingham SJ, Yacoub MH (1990) Determination of sixteen nucleotides, nucleosides and bases using high-performance liquid chromatography and its application to the study of purine metabolism in hearts for transplantation. J Chromatogr 527:414–420