Automated liquid culture system misses isoniazid heteroresistance in Mycobacterium tuberculosis isolates with mutations in the promoter region of the inhA gene

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 34, Issue 3, 2015, Pages 555-560

  Zhang, Z ^a,b   Lu, J ^c   Wang, Y ^b   Pang, Y ^a,b   Zhao, Y ^b  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^c CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ISONIAZID; KATG PROTEIN; BACTERIAL PROTEIN; INHA PROTEIN, MYCOBACTERIUM; OXIDOREDUCTASE; TUBERCULOSTATIC AGENT;

ANTIBIOTIC RESISTANCE; ARTICLE; AUTOMATION; BACTERIAL GROWTH; BACTERIUM ISOLATION; BROTH DILUTION; DRUG SENSITIVITY; DRUG SUSCEPTIBILITY TESTING; GENE MUTATION; GROWTH REGULATION; LIMIT OF DETECTION; LIQUID CULTURE; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROMOTER REGION; DRUG EFFECTS; EVALUATION STUDY; GENETICS; HUMAN; LABORATORY AUTOMATION; LABORATORY DIAGNOSIS; MICROBIAL SENSITIVITY TEST; MUTATION; PROCEDURES; SENSITIVITY AND SPECIFICITY;

ANTITUBERCULAR AGENTS; AUTOMATION, LABORATORY; BACTERIAL PROTEINS; FALSE NEGATIVE REACTIONS; HUMANS; ISONIAZID; MICROBIAL SENSITIVITY TESTS; MUTATION; MYCOBACTERIUM TUBERCULOSIS; OXIDOREDUCTASES; PROMOTER REGIONS, GENETIC; SENSITIVITY AND SPECIFICITY;

EID: 84941742347     PISSN: 09349723     EISSN: 14354373     Source Type: Journal    
DOI: 10.1007/s10096-014-2262-0     Document Type: Article

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