Rifampin resistance missed in automated liquid culture system for Mycobacterium tuberculosis isolates with specific rpoB mutations

Journal of Clinical Microbiology

Volumn 51, Issue 8, 2013, Pages 2641-2645

  Rigouts, Leen ^a,b   Gumusboga, Mourad ^a   De Rijk, Willem Bram ^a   Nduwamahoro, Elie ^a   Uwizeye, Cécile ^a   De Jong, Bouke ^a   Van Deun, Armand ^a  

^a INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^b UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

RIFAMPICIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; AUTOMATION; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIUM CULTURE; CODON; CONTROLLED STUDY; CULTURE MEDIUM; DRUG SCREENING; DRUG SUSCEPTIBILITY TESTING; GENE MUTATION; GENOTYPE; INTERMETHOD COMPARISON; LOEWENSTEIN MEDIUM; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR TYPING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RPOB GENE;

ANTITUBERCULAR AGENTS; AUTOMATION, LABORATORY; BACTERIAL PROTEINS; CULTURE MEDIA; DIAGNOSTIC ERRORS; DRUG RESISTANCE, BACTERIAL; HUMANS; MICROBIAL SENSITIVITY TESTS; MUTATION, MISSENSE; MYCOBACTERIUM TUBERCULOSIS; RIFAMPIN;

EID: 84880576143     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.02741-12     Document Type: Article

References (23)

1. Anonymous. 2011. The worldwide epidemic of multidrug-resistant tuberculosis. Editorial. Lancet Infect. Dis. 11:333.
2. Martin A, Panaiotov S, Portaels F, Hoffner S, Palomino JC, Ängeby K. 2008. The nitrate reductase assay for the rapid detection of isoniazid and rifampicin resistance in Mycobacterium tuberculosis: a systematic review and meta-analysis. J. Antimicrob. Chemother. 62:56-64.
3. Palomino JC, Martin A, Camacho M, Guerra H, Swings J, Portaels F. 2002. Resazurin microtiter assay plate: simple and inexpensive method for detection of drug resistance in Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 46:2720-2722.
4. Moore DAJ, Mendoza D, Gilman RH, Evans CAW, Hollm Delgado MG, Guerra J, Caviedes L, Vargas D, Ticona E, Ortiz J, Soto G, Serpa J. 2004. Microscopic observation drug susceptibility assay, a rapid, reliable diagnostic test for multidrug-resistant tuberculosis suitable for use in resource-poor settings. J. Clin. Microbiol. 42:4432-4437.
5. Lemus D, Martin A, Montoro E, Portaels F, Palomino JC. 2004. Rapid alternative methods for detection of rifampicin resistance in Mycobacterium tuberculosis. J. Antimicrob. Chemother. 54:130-133.
6. Campbell PJ, Morlock GP, Sikes RD, Dalton TL, Metchock B, Starks AM, Hooks DP, Cowan LS, Plikaytis BB, Posey JE. 2011. Molecular detection of mutations associated with first- and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 55:2032-2041.
7. Ramaswamy S, Musser JM. 1998. Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 update. Tuber. Lung Dis. 79:3-29.
8. Barry CE, Stayden RA, III, Mdluli K. 1998. Mechanisms of isoniazid resistance in Mycobacterium tuberculosis. Drug Res. Update 1:128-134.
9. Van Deun A, Barrera L, Bastian I, Fattorini L, Hoffmann H, Kam KM, Rigouts L, Rüsch-Gerdes S, Wright A. 2009. Mycobacterium tuberculosis strains with highly discordant rifampin susceptibility test results. J. Clin. Microbiol. 47:3501-3506.
10. Rigouts L, Nolasco O, de Rijk P, Nduwamahoro E, Van Deun A, Ramsay A, Arevalo J, Portaels F. 2007. Newly developed primers for comprehensive amplification of the rpoB gene and detection of rifampin resistance in Mycobacterium tuberculosis. J. Clin. Microbiol. 45:252-254.
11. Canetti G, Froman S, Grosset J, Hauduroy P, Langerova M, Mahler HT, Meissner G, Mitchison DA, Sula L. 1963. Mycobacteria: laboratory methods for testing drug sensitivity and resistance. Bull. World Health Organ. 29:565-578.
12. Kamerbeek J, Schouls L, Kolik A, van Agterveld M, van Soolingen D, Kuijper S, Bunschoten A, Molhuizen H, Shaw R, Goyal M, van Embden J. 1997. Simultaneous detection and strain differentiation of Mycobacterium tuberculosis for diagnosis and epidemiology. J. Clin. Microbiol. 35: 907-914.
13. Victor TC, Warren R, Butt JL, Jordaan AM, Felix JV, Venter A, Sirgel FA, Schaaf HS, Donald PR, Richardson M, Cynamon MH, van Helden PD. 1997. Genome and MIC stability in Mycobacterium tuberculosis and indications for continuation of use of isoniazid in multidrug-resistant tuberculosis. Med. Microbiol. 46:847-857.
14. Ohno H, Koga H, Kuroita T, Tomono K, Ogawa K, Yanagihara K, Yamamoto Y, Miyamoto J, Tashiro T, Kohno S. 1997. Rapid prediction of rifampin susceptibility of Mycobacterium tuberculosis. Am J. Respir. Crit. Care Med. 155:2057-2063.
15. Van Deun A, Aung KJM, Bola V, Lebeke R, Hossain MA, de Rijk WB, Rigouts L, Gumusboga A, Torrea G, de Jong BC. 2013. Rifampin drug resistance tests for tuberculosis: challenging the gold standard. J. Clin. Microbiol. 51:2633-2640.
16. Williamson DA, Roberts SA, Bower JE, Vaughan R, Newton S, Lowe O, Lewis CA, Freeman JT. 2012. Clinical failures associated with rpoB mutations in phenotypically occult multidrug-resistant Mycobacterium tuberculosis. Int. J. Tuberc. Lung Dis. 16:216-220.
17. World Health Organization. 2011. Rapid implementation of the Xpert MTB/RIF diagnostic test. Technical and operational "How to" practical considerations. World Health Organization document WHO/HTM/TB/2011.2.
18. Billington OJ, McHugh TD, Gillespie SH. 1999. Physiological cost of rifampin resistance induced in vitro in Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 43:1866-1869.
19. Gagneux S, Davis Long C, Small PM, Van T, Schoolnik GK, Bohannan BJM. 2006. The competitive cost of antibiotic resistance in Mycobacterium tuberculosis. Science 312:1944-1946.
20. Mariam DH, Mengistu Y, Hoffner SE, Andersson DI. 2004. Effect of rpoB mutations conferring rifampin resistance on fitness of Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 48:1289-1294.
21. Ahmad S, Al-Mutairi N, Mokaddas E. 2009. Comparison of performance of two DNA line probe assays for rapid detection of multidrugresistant isolates of Mycobacterium tuberculosis. Indian J. Exp. Biol. 47: 454-462.
22. Al-Mutairi NM, Ahmad S, Mokaddas E. 2011. Performance comparison of four methods for detecting multidrug-resistant Mycobacterium tuberculosis strains. Int. J. Tuberc. Lung Dis. 15:110-115.
23. Chen L, Gan X, Li N, Wang J, Li K, Zhang H. 2010. rpoB gene mutation profile in rifampicin-resistant Mycobacterium tuberculosis clinical isolates from Guizhou, one of the highest incidence rate regions in China. J. Antimicrob. Chemother 65:1299-1301.