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Volumn 132, Issue 4, 2015, Pages 231-240

Clozapine-induced myocarditis, a widely overlooked adverse reaction

Author keywords

Clozapine; Drug related side effects and adverse reactions; Incidence; Myocarditis

Indexed keywords

CLOZAPINE; NEUROLEPTIC AGENT;

EID: 84941742118     PISSN: 0001690X     EISSN: 16000447     Source Type: Journal    
DOI: 10.1111/acps.12416     Document Type: Review
Times cited : (127)

References (92)
  • 1
    • 25144466069 scopus 로고    scopus 로고
    • The choice of antipsychotic drugs for schizophrenia
    • Freedman R. The choice of antipsychotic drugs for schizophrenia. N Engl J Med 2005;353:1286-1288.
    • (2005) N Engl J Med , vol.353 , pp. 1286-1288
    • Freedman, R.1
  • 2
    • 58049157203 scopus 로고    scopus 로고
    • Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis
    • Leucht S, Corves C, Arbter D, Engel RR, Li C, Davis JM. Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis. Lancet 2009;373:31-41.
    • (2009) Lancet , vol.373 , pp. 31-41
    • Leucht, S.1    Corves, C.2    Arbter, D.3    Engel, R.R.4    Li, C.5    Davis, J.M.6
  • 3
    • 84865322363 scopus 로고    scopus 로고
    • Clozapine for the treatment of schizophrenia
    • Fakra E, Azorin JM. Clozapine for the treatment of schizophrenia. Expert Opin Pharmacother 2012;13:1923-1935.
    • (2012) Expert Opin Pharmacother , vol.13 , pp. 1923-1935
    • Fakra, E.1    Azorin, J.M.2
  • 5
    • 0033610722 scopus 로고    scopus 로고
    • Myocarditis and cardiomyopathy associated with clozapine
    • Kilian JG, Kerr K, Lawrence C, Celermajer DS. Myocarditis and cardiomyopathy associated with clozapine. Lancet 1999;354:1841-1845.
    • (1999) Lancet , vol.354 , pp. 1841-1845
    • Kilian, J.G.1    Kerr, K.2    Lawrence, C.3    Celermajer, D.S.4
  • 6
    • 33846074353 scopus 로고    scopus 로고
    • Clozapine-associated myocarditis: a review of 116 cases of suspected myocarditis associated with the use of clozapine in Australia during 1993-2003
    • Haas SJ, Hill R, Krum H et al. Clozapine-associated myocarditis: a review of 116 cases of suspected myocarditis associated with the use of clozapine in Australia during 1993-2003. Drug Saf 2007;30:47-57.
    • (2007) Drug Saf , vol.30 , pp. 47-57
    • Haas, S.J.1    Hill, R.2    Krum, H.3
  • 9
    • 55249117530 scopus 로고    scopus 로고
    • Clozapine and myocarditis: a case series from the New Zealand Intensive Medicines Monitoring Programme
    • Hill GR, Harrison-Woolrych M. Clozapine and myocarditis: a case series from the New Zealand Intensive Medicines Monitoring Programme. N Z Med J 2008;121:68-74.
    • (2008) N Z Med J , vol.121 , pp. 68-74
    • Hill, G.R.1    Harrison-Woolrych, M.2
  • 10
    • 84868155778 scopus 로고    scopus 로고
    • Beyond white blood cell monitoring: screening in the initial phase of clozapine therapy
    • Cohen D, Bogers JP, van Dijk D, Bakker B, Schulte PF. Beyond white blood cell monitoring: screening in the initial phase of clozapine therapy. J Clin Psychiatry 2012;73:1307-1312.
    • (2012) J Clin Psychiatry , vol.73 , pp. 1307-1312
    • Cohen, D.1    Bogers, J.P.2    van Dijk, D.3    Bakker, B.4    Schulte, P.F.5
  • 11
    • 11144267254 scopus 로고    scopus 로고
    • Clozapine-related myocarditis and cardiomyopathy in an Australian metropolitan psychiatric service
    • Reinders J, Parsonage W, Lange D, Potter JM, Plever S. Clozapine-related myocarditis and cardiomyopathy in an Australian metropolitan psychiatric service. Aust N Z J Psychiatry 2004;38:915-922.
    • (2004) Aust N Z J Psychiatry , vol.38 , pp. 915-922
    • Reinders, J.1    Parsonage, W.2    Lange, D.3    Potter, J.M.4    Plever, S.5
  • 12
    • 0021893976 scopus 로고
    • ECG changes developing during clozapine treatment
    • Beier J, Haastrup S. ECG changes developing during clozapine treatment. Ugeskr Laeger 1985;147:619-620.
    • (1985) Ugeskr Laeger , vol.147 , pp. 619-620
    • Beier, J.1    Haastrup, S.2
  • 13
    • 0021962263 scopus 로고
    • Tolerability and therapeutic effect of clozapine. A retrospective investigation of 216 patients treated with clozapine for up to 12 years
    • Juul Povlsen U, Noring U, Fog R, Gerlach J. Tolerability and therapeutic effect of clozapine. A retrospective investigation of 216 patients treated with clozapine for up to 12 years. Acta Psychiatr Scand 1985;71:176-185.
    • (1985) Acta Psychiatr Scand , vol.71 , pp. 176-185
    • Juul Povlsen, U.1    Noring, U.2    Fog, R.3    Gerlach, J.4
  • 14
    • 0023951942 scopus 로고
    • The effect of long-term treatment with clozapine in schizophrenia: a retrospective study in 96 patients treated with clozapine for up to 13 years
    • Lindstrom LH. The effect of long-term treatment with clozapine in schizophrenia: a retrospective study in 96 patients treated with clozapine for up to 13 years. Acta Psychiatr Scand 1988;77:524-529.
    • (1988) Acta Psychiatr Scand , vol.77 , pp. 524-529
    • Lindstrom, L.H.1
  • 15
    • 0026516617 scopus 로고
    • Clozapine tissue concentrations following an apparent suicidal overdose of Clozaril
    • Meeker JE, Herrmann PW, Som CW, Reynolds PC. Clozapine tissue concentrations following an apparent suicidal overdose of Clozaril. J Anal Toxicol 1992;16:54-56.
    • (1992) J Anal Toxicol , vol.16 , pp. 54-56
    • Meeker, J.E.1    Herrmann, P.W.2    Som, C.W.3    Reynolds, P.C.4
  • 16
    • 0028771184 scopus 로고
    • Allergic myocarditis in clozapine treatment
    • Jensen VE, Gotzsche O. Allergic myocarditis in clozapine treatment. Ugeskr Laeger 1994;156:4151-4152.
    • (1994) Ugeskr Laeger , vol.156 , pp. 4151-4152
    • Jensen, V.E.1    Gotzsche, O.2
  • 19
    • 0031045055 scopus 로고    scopus 로고
    • Peri-/myocarditis with clozapine (Leponex)
    • Khalil N. Peri-/myocarditis with clozapine (Leponex). Psychiatr Prax 1997;24:46.
    • (1997) Psychiatr Prax , vol.24 , pp. 46
    • Khalil, N.1
  • 20
    • 0035704443 scopus 로고    scopus 로고
    • Reversible myocarditis in a patient receiving clozapine
    • Kirpekar VC, Deshpande SM, Joshi PP. Reversible myocarditis in a patient receiving clozapine. Indian Heart J 2001;53:779-781.
    • (2001) Indian Heart J , vol.53 , pp. 779-781
    • Kirpekar, V.C.1    Deshpande, S.M.2    Joshi, P.P.3
  • 21
    • 0035032483 scopus 로고    scopus 로고
    • Clozapine rechallenge after myocarditis
    • Reid P. Clozapine rechallenge after myocarditis. Aust N Z J Psychiatry 2001;35:249.
    • (2001) Aust N Z J Psychiatry , vol.35 , pp. 249
    • Reid, P.1
  • 22
    • 0036205483 scopus 로고    scopus 로고
    • Clozapine associated pericarditis and elevated troponin I
    • Kay SE, Doery J, Sholl D. Clozapine associated pericarditis and elevated troponin I. Aust N Z J Psychiatry 2002;36:143-144.
    • (2002) Aust N Z J Psychiatry , vol.36 , pp. 143-144
    • Kay, S.E.1    Doery, J.2    Sholl, D.3
  • 23
    • 0036091820 scopus 로고    scopus 로고
    • Clozapine-associated cardiomyopathy
    • Phan KL, Taylor SF. Clozapine-associated cardiomyopathy. Psychosomatics 2002;43:248.
    • (2002) Psychosomatics , vol.43 , pp. 248
    • Phan, K.L.1    Taylor, S.F.2
  • 24
    • 6344275647 scopus 로고    scopus 로고
    • Sudden cardiac death due to hypersensitivity myocarditis during clozapine treatment
    • Fineschi V, Neri M, Riezzo I, Turillazzi E. Sudden cardiac death due to hypersensitivity myocarditis during clozapine treatment. Int J Legal Med 2004;118:307-309.
    • (2004) Int J Legal Med , vol.118 , pp. 307-309
    • Fineschi, V.1    Neri, M.2    Riezzo, I.3    Turillazzi, E.4
  • 26
    • 33745842230 scopus 로고    scopus 로고
    • Clozapine induced myopericarditis: early recognition improves clinical outcome
    • Razminia M, Salem Y, Devaki S, Shah N, Khosla S. Clozapine induced myopericarditis: early recognition improves clinical outcome. Am J Ther 2006;13:274-276.
    • (2006) Am J Ther , vol.13 , pp. 274-276
    • Razminia, M.1    Salem, Y.2    Devaki, S.3    Shah, N.4    Khosla, S.5
  • 28
    • 84992769705 scopus 로고    scopus 로고
    • Clozapine and heart in the Hunter region
    • Tirupati S. Clozapine and heart in the Hunter region. Aust N Z J Psychiatry 2006;40:97.
    • (2006) Aust N Z J Psychiatry , vol.40 , pp. 97
    • Tirupati, S.1
  • 30
    • 34447507806 scopus 로고    scopus 로고
    • Acute myocarditis associated with clozapine
    • Varambally S, Howpage P. Acute myocarditis associated with clozapine. Australas Psychiatry 2007;15:343-346.
    • (2007) Australas Psychiatry , vol.15 , pp. 343-346
    • Varambally, S.1    Howpage, P.2
  • 31
    • 33947165756 scopus 로고    scopus 로고
    • Myocarditis associated with clozapine studied by cardiovascular magnetic resonance
    • Belloni E, de Cobelli F, Esposito A et al. Myocarditis associated with clozapine studied by cardiovascular magnetic resonance. J Cardiovasc Magn Reson 2007;9:591-593.
    • (2007) J Cardiovasc Magn Reson , vol.9 , pp. 591-593
    • Belloni, E.1    de Cobelli, F.2    Esposito, A.3
  • 35
    • 70849125132 scopus 로고    scopus 로고
    • Monitoring of clozapine-induced myocarditis
    • Caetano D. Monitoring of clozapine-induced myocarditis. Australas Psychiatry 2009;17:421.
    • (2009) Australas Psychiatry , vol.17 , pp. 421
    • Caetano, D.1
  • 36
  • 37
    • 77952868191 scopus 로고    scopus 로고
    • Cardiovascular magnetic resonance in mild to moderate clozapine-induced myocarditis: is there a role in the absence of electrocardiographic and echocardiographic abnormalities?
    • Ariyarajah V, Shaikh N, Garber PJ, Kirkpatrick I, McGregor R, Jassal DS. Cardiovascular magnetic resonance in mild to moderate clozapine-induced myocarditis: is there a role in the absence of electrocardiographic and echocardiographic abnormalities? J Magn Reson Imaging 2010;31:1473-1476.
    • (2010) J Magn Reson Imaging , vol.31 , pp. 1473-1476
    • Ariyarajah, V.1    Shaikh, N.2    Garber, P.J.3    Kirkpatrick, I.4    McGregor, R.5    Jassal, D.S.6
  • 38
    • 77955628908 scopus 로고    scopus 로고
    • The safety and tolerability of clozapine in aged patients: a retrospective clinical file review
    • O'connor DW, Sierakowski C, Chin LF, Singh D. The safety and tolerability of clozapine in aged patients: a retrospective clinical file review. World J Biol Psychiatry 2010;11:788-791.
    • (2010) World J Biol Psychiatry , vol.11 , pp. 788-791
    • O'connor, D.W.1    Sierakowski, C.2    Chin, L.F.3    Singh, D.4
  • 40
    • 77955300647 scopus 로고    scopus 로고
    • Clozapine rechallenge following clozapine-induced pericarditis
    • Crews MP, Dhillon GS, MacCabe JH. Clozapine rechallenge following clozapine-induced pericarditis. J Clin Psychiatry 2010;71:959-961.
    • (2010) J Clin Psychiatry , vol.71 , pp. 959-961
    • Crews, M.P.1    Dhillon, G.S.2    MacCabe, J.H.3
  • 43
    • 78650675407 scopus 로고    scopus 로고
    • Successful clozapine rechallenge after acute myocarditis
    • Bray A, Reid R. Successful clozapine rechallenge after acute myocarditis. Aust NZ J Psychiatry 2011;45:90.
    • (2011) Aust NZ J Psychiatry , vol.45 , pp. 90
    • Bray, A.1    Reid, R.2
  • 44
    • 84865419978 scopus 로고    scopus 로고
    • The difficulties of diagnosing clozapine myocarditis: damned if you do, damned if you don't
    • Power B, Williams H, Shymko G. The difficulties of diagnosing clozapine myocarditis: damned if you do, damned if you don't. Australas Psychiatry 2012;20:165-166.
    • (2012) Australas Psychiatry , vol.20 , pp. 165-166
    • Power, B.1    Williams, H.2    Shymko, G.3
  • 45
    • 84875139605 scopus 로고    scopus 로고
    • Multimodality cardiac imaging in Clozapine-induced eosinophilic constrictive perimyocarditis
    • Albouaini K, Ruzsics B, Chenzbraun A. Multimodality cardiac imaging in Clozapine-induced eosinophilic constrictive perimyocarditis. Eur Heart J Cardiovasc Imaging 2013;14:338.
    • (2013) Eur Heart J Cardiovasc Imaging , vol.14 , pp. 338
    • Albouaini, K.1    Ruzsics, B.2    Chenzbraun, A.3
  • 46
    • 84876194600 scopus 로고    scopus 로고
    • Successful re-exposure to clozapine after eosinophilia and clinically suspected myocarditis
    • Granja-Ingram NM, James J, Clark N, Stovall J, Heckers S. Successful re-exposure to clozapine after eosinophilia and clinically suspected myocarditis. Rev Bras Psiquiatr 2013;35:95-96.
    • (2013) Rev Bras Psiquiatr , vol.35 , pp. 95-96
    • Granja-Ingram, N.M.1    James, J.2    Clark, N.3    Stovall, J.4    Heckers, S.5
  • 48
    • 84886310149 scopus 로고    scopus 로고
    • Clozapine-induced cardiomyopathy: a first case in Japan
    • Kikuchi Y, Ataka K, Yagisawa K et al. Clozapine-induced cardiomyopathy: a first case in Japan. Schizophr Res 2013;150:586-587.
    • (2013) Schizophr Res , vol.150 , pp. 586-587
    • Kikuchi, Y.1    Ataka, K.2    Yagisawa, K.3
  • 49
    • 84897455516 scopus 로고    scopus 로고
    • Successful rechallenge of clozapine therapy following previous clozapine-induced myocarditis confirmed on cardiac MRI
    • Chow V, Feijo I, Trieu J, Starling J, Kritharides L. Successful rechallenge of clozapine therapy following previous clozapine-induced myocarditis confirmed on cardiac MRI. J Child Adolesc Psychopharmacol 2014;24:99-101.
    • (2014) J Child Adolesc Psychopharmacol , vol.24 , pp. 99-101
    • Chow, V.1    Feijo, I.2    Trieu, J.3    Starling, J.4    Kritharides, L.5
  • 50
    • 84921631829 scopus 로고    scopus 로고
    • Clozapine-induced myocarditis: is mandatory monitoring warranted for its early recognition?
    • 2014:513108.
    • Munshi TA, Volochniouk D, Hassan T, Mazhar N. Clozapine-induced myocarditis: is mandatory monitoring warranted for its early recognition? Case Rep Psychiatry 2014;2014:513108.
    • (2014) Case Rep Psychiatry
    • Munshi, T.A.1    Volochniouk, D.2    Hassan, T.3    Mazhar, N.4
  • 51
    • 0003191986 scopus 로고
    • Myocarditis with antipsychotics: recent cases with clozapine (Clozaril)
    • Internet:(Accessed 8 Oct 2013).
    • Committee on Safety of Medicines. Myocarditis with antipsychotics: recent cases with clozapine (Clozaril). Curr Prob Pharmacovigil 1993;19:9-10. Internet: http://www.mhra.gov.uk/home/idcplg?IdcService=GET_FILE&dDocName=CON2024456&RevisionSelectionMethod=LatestReleased (Accessed 8 Oct 2013).
    • (1993) Curr Prob Pharmacovigil , vol.19 , pp. 9-10
  • 54
    • 0035913277 scopus 로고    scopus 로고
    • Myocarditis and cardiomyopathy associated with clozapine use in the United States
    • la Grenade L, Graham D, Trontell A. Myocarditis and cardiomyopathy associated with clozapine use in the United States. N Engl J Med 2001;345:224-225.
    • (2001) N Engl J Med , vol.345 , pp. 224-225
    • la Grenade, L.1    Graham, D.2    Trontell, A.3
  • 55
    • 0036257674 scopus 로고    scopus 로고
    • Antipsychotic clozapine (Clozaril): Myocarditis and cardiovascular toxicity
    • Wooltorton E. Antipsychotic clozapine (Clozaril): Myocarditis and cardiovascular toxicity. Can Med Assoc J 2002;166:1185-1186.
    • (2002) Can Med Assoc J , vol.166 , pp. 1185-1186
    • Wooltorton, E.1
  • 56
    • 84880723218 scopus 로고    scopus 로고
    • Echocardiographic monitoring for clozapine cardiac toxicity: lessons from real-world experience
    • Murch S, Tran N, Liew D, Petrakis M, Prior D, Castle D. Echocardiographic monitoring for clozapine cardiac toxicity: lessons from real-world experience. Australas Psychiatry 2013;21:258-261.
    • (2013) Australas Psychiatry , vol.21 , pp. 258-261
    • Murch, S.1    Tran, N.2    Liew, D.3    Petrakis, M.4    Prior, D.5    Castle, D.6
  • 57
    • 0035912544 scopus 로고    scopus 로고
    • Antipsychotic drugs and heart muscle disorder in international pharmacovigilance: data mining study
    • Coulter DM, Bate A, Meyboom RH, Lindquist M, Edwards IR. Antipsychotic drugs and heart muscle disorder in international pharmacovigilance: data mining study. BMJ 2001;322:1207-1209.
    • (2001) BMJ , vol.322 , pp. 1207-1209
    • Coulter, D.M.1    Bate, A.2    Meyboom, R.H.3    Lindquist, M.4    Edwards, I.R.5
  • 58
    • 79955978927 scopus 로고    scopus 로고
    • A new monitoring protocol for clozapine induced myocarditis based on an analysis of 75 cases and 94 controls
    • Ronaldson KJ, Taylor AJ, Fitzgerald PB, Topliss DJ, McNeil JJ. A new monitoring protocol for clozapine induced myocarditis based on an analysis of 75 cases and 94 controls. Aust NZ J Psychiatry 2011;45:458-465.
    • (2011) Aust NZ J Psychiatry , vol.45 , pp. 458-465
    • Ronaldson, K.J.1    Taylor, A.J.2    Fitzgerald, P.B.3    Topliss, D.J.4    McNeil, J.J.5
  • 59
    • 79955474912 scopus 로고    scopus 로고
    • Clinical course and analysis of ten fatal cases of clozapine-induced myocarditis and comparison with 66 surviving cases
    • Ronaldson KJ, Taylor AJ, Fitzgerald PB, Topliss DJ, McNeil JJ. Clinical course and analysis of ten fatal cases of clozapine-induced myocarditis and comparison with 66 surviving cases. Schizophr Res 2011;128:161-165.
    • (2011) Schizophr Res , vol.128 , pp. 161-165
    • Ronaldson, K.J.1    Taylor, A.J.2    Fitzgerald, P.B.3    Topliss, D.J.4    McNeil, J.J.5
  • 61
    • 21244440442 scopus 로고    scopus 로고
    • Myocarditis, pericarditis and cardiomyopathy in patients treated with clozapine
    • Wehmeier PM, Heiser P, Remschmidt H. Myocarditis, pericarditis and cardiomyopathy in patients treated with clozapine. J Clin Pharm Ther 2005;30:91-96.
    • (2005) J Clin Pharm Ther , vol.30 , pp. 91-96
    • Wehmeier, P.M.1    Heiser, P.2    Remschmidt, H.3
  • 62
    • 3342931111 scopus 로고    scopus 로고
    • Chart review for potential features of myocarditis, pericarditis, and cardiomyopathy in children and adolescents treated with clozapine
    • Wehmeier PM, Schuler-Springorum M, Heiser P, Remschmidt H. Chart review for potential features of myocarditis, pericarditis, and cardiomyopathy in children and adolescents treated with clozapine. J Child Adolesc Psychopharmacol 2004;14:267-271.
    • (2004) J Child Adolesc Psychopharmacol , vol.14 , pp. 267-271
    • Wehmeier, P.M.1    Schuler-Springorum, M.2    Heiser, P.3    Remschmidt, H.4
  • 63
    • 84866908977 scopus 로고    scopus 로고
    • Rapid clozapine dose titration and concomitant sodium valproate increase the risk of myocarditis with clozapine: a case-control study
    • Ronaldson KJ, Fitzgerald PB, Taylor AJ, Topliss DJ, Wolfe R, McNeil JJ. Rapid clozapine dose titration and concomitant sodium valproate increase the risk of myocarditis with clozapine: a case-control study. Schizophr Res 2012;141:173-178.
    • (2012) Schizophr Res , vol.141 , pp. 173-178
    • Ronaldson, K.J.1    Fitzgerald, P.B.2    Taylor, A.J.3    Topliss, D.J.4    Wolfe, R.5    McNeil, J.J.6
  • 64
    • 84941744742 scopus 로고    scopus 로고
    • Clozaril (clozapine) Product Information, Australia (26 Aug 2014):(Accessed 16 Oct).
    • Novartis Pharmaceuticals Australia Pty Ltd. Clozaril (clozapine) Product Information, Australia (26 Aug 2014): https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2009-PI-00043-3 (Accessed 16 Oct 2014).
    • (2014)
  • 65
    • 84941743157 scopus 로고    scopus 로고
    • Clozaril (clozapine) Label, USA (29 Sep 2014):(Accessed 16 Oct).
    • Novartis Pharmaceuticals Corporation. Clozaril (clozapine) Label, USA (29 Sep 2014): http://www.accessdata.fda.gov/drugsatfda_docs/label/2014/019758s072lbl.pdf (Accessed 16 Oct 2014).
    • (2014)
  • 66
    • 84941736138 scopus 로고    scopus 로고
    • Clozaril (clozapine) Summary of Product characteristics, United Kingdom (14 Apr 2014):(Accessed 16 Oct 2014).
    • Novartis Pharmaceuticals UK Limited. Clozaril (clozapine) Summary of Product characteristics, United Kingdom (14 Apr 2014): http://www.mhra.gov.uk/home/groups/spcpil/documents/spcpil/con1410501563443.pdf (Accessed 16 Oct 2014).
    • (2014)
  • 68
    • 77956008256 scopus 로고    scopus 로고
    • Diagnostic characteristics of clozapine induced myocarditis identified by an analysis of 38 cases and 47 controls
    • Ronaldson KJ, Taylor AJ, Fitzgerald PB, Topliss DJ, Elsik M, McNeil JJ. Diagnostic characteristics of clozapine induced myocarditis identified by an analysis of 38 cases and 47 controls. J Clin Psych 2010;71:976-981.
    • (2010) J Clin Psych , vol.71 , pp. 976-981
    • Ronaldson, K.J.1    Taylor, A.J.2    Fitzgerald, P.B.3    Topliss, D.J.4    Elsik, M.5    McNeil, J.J.6
  • 71
    • 58149260289 scopus 로고    scopus 로고
    • The incidence and characteristics of clozapine- induced fever in a local psychiatric unit in Hong Kong
    • Chung JP, Chong CS, Chung K, Dunn EL, Wai-Nang Tang OW, Chan W. The incidence and characteristics of clozapine- induced fever in a local psychiatric unit in Hong Kong. Can J Psychiatry 2008;53:857-862.
    • (2008) Can J Psychiatry , vol.53 , pp. 857-862
    • Chung, J.P.1    Chong, C.S.2    Chung, K.3    Dunn, E.L.4    Wai-Nang Tang, O.W.5    Chan, W.6
  • 72
    • 0036774571 scopus 로고    scopus 로고
    • Clozapine-induced fevers and 1-year clozapine discontinuation rate
    • Tham JC, Dickson RA. Clozapine-induced fevers and 1-year clozapine discontinuation rate. J Clin Psych 2002;63:880-884.
    • (2002) J Clin Psych , vol.63 , pp. 880-884
    • Tham, J.C.1    Dickson, R.A.2
  • 75
    • 0024443179 scopus 로고
    • Efficacy and adverse effects of clozapine in the treatment of schizophrenia and tardive dyskinesia-a retrospective study of 387 patients
    • Naber D, Leppig M, Grohmann R, Hippius H. Efficacy and adverse effects of clozapine in the treatment of schizophrenia and tardive dyskinesia-a retrospective study of 387 patients. Psychopharmacology 1989;99(Suppl):S73-S76.
    • (1989) Psychopharmacology , vol.99 , Issue.Suppl , pp. S73-S76
    • Naber, D.1    Leppig, M.2    Grohmann, R.3    Hippius, H.4
  • 76
    • 0027212612 scopus 로고
    • Spiking fever and profuse diarrhea with clozapine treatment
    • Patterson BD, Jennings JL. Spiking fever and profuse diarrhea with clozapine treatment. Am J Psychiatry 1993;150:1126.
    • (1993) Am J Psychiatry , vol.150 , pp. 1126
    • Patterson, B.D.1    Jennings, J.L.2
  • 78
    • 58549111991 scopus 로고    scopus 로고
    • Increases in C-reactive protein may predict recurrence of clozapine-induced fever
    • Kohen I, Afzal N, Hussain S, Manu P. Increases in C-reactive protein may predict recurrence of clozapine-induced fever. Ann Pharmacother 2009;43:143-146.
    • (2009) Ann Pharmacother , vol.43 , pp. 143-146
    • Kohen, I.1    Afzal, N.2    Hussain, S.3    Manu, P.4
  • 79
    • 84879643745 scopus 로고    scopus 로고
    • Management of clozapine-induced fever: a case of continued therapy throughout fever
    • Martin N, Williams R. Management of clozapine-induced fever: a case of continued therapy throughout fever. J Psychiatry Neurosci 2013;38:E9-E10.
    • (2013) J Psychiatry Neurosci , vol.38 , pp. E9-E10
    • Martin, N.1    Williams, R.2
  • 80
    • 84885716729 scopus 로고    scopus 로고
    • Clozapine-induced elevated C-reactive protein and fever mimic infection
    • e5-6.
    • Štuhec M. Clozapine-induced elevated C-reactive protein and fever mimic infection. Gen Hosp Psychiatry 2013;35:680. e5-6.
    • (2013) Gen Hosp Psychiatry , vol.35 , pp. 680
    • Štuhec, M.1
  • 81
    • 84898724764 scopus 로고    scopus 로고
    • Management of clozapine-induced fever in a child
    • Driver DI, Anvari AA, Peroutka CM et al. Management of clozapine-induced fever in a child. Am J Psychiatry 2014;171:398-402.
    • (2014) Am J Psychiatry , vol.171 , pp. 398-402
    • Driver, D.I.1    Anvari, A.A.2    Peroutka, C.M.3
  • 85
    • 58349114259 scopus 로고    scopus 로고
    • Atypical antipsychotic drugs and the risk of sudden cardiac death
    • Ray WA, Chung CP, Murray KT, Hall K, Stein MC. Atypical antipsychotic drugs and the risk of sudden cardiac death. N Engl J Med 2009;360:225-235.
    • (2009) N Engl J Med , vol.360 , pp. 225-235
    • Ray, W.A.1    Chung, C.P.2    Murray, K.T.3    Hall, K.4    Stein, M.C.5
  • 88
    • 84867640817 scopus 로고    scopus 로고
    • Update on the adverse effects of clozapine: focus on myocarditis
    • de Berardis D, Serroni N, Campanella D et al. Update on the adverse effects of clozapine: focus on myocarditis. Curr Drug Saf 2012;7:55-62.
    • (2012) Curr Drug Saf , vol.7 , pp. 55-62
    • de Berardis, D.1    Serroni, N.2    Campanella, D.3
  • 89
    • 60149100470 scopus 로고    scopus 로고
    • Reasons for discontinuing clozapine: matched, case-control comparison with risperidone long-acting injection
    • Taylor DM, Douglas-Hall P, Olofinjana B, Whiskey E, Thomas A. Reasons for discontinuing clozapine: matched, case-control comparison with risperidone long-acting injection. Br J Psychiatry 2009;194:165-167.
    • (2009) Br J Psychiatry , vol.194 , pp. 165-167
    • Taylor, D.M.1    Douglas-Hall, P.2    Olofinjana, B.3    Whiskey, E.4    Thomas, A.5
  • 90
    • 58249089282 scopus 로고    scopus 로고
    • Cardiac-related findings at autopsy in people with severe mental illness treated with clozapine or risperidone
    • Kelly DL, Wehring HJ, Linthicum J et al. Cardiac-related findings at autopsy in people with severe mental illness treated with clozapine or risperidone. Schizophr Res 2009;107:134-138.
    • (2009) Schizophr Res , vol.107 , pp. 134-138
    • Kelly, D.L.1    Wehring, H.J.2    Linthicum, J.3
  • 92
    • 84876533595 scopus 로고    scopus 로고
    • Second-generation antipsychotic medications and risk of pneumonia in schizophrenia
    • Kuo C, Yang SY, Liao YT et al. Second-generation antipsychotic medications and risk of pneumonia in schizophrenia. Schizophr Bull 2013;39:648-657.
    • (2013) Schizophr Bull , vol.39 , pp. 648-657
    • Kuo, C.1    Yang, S.Y.2    Liao, Y.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.