Blockade of Ets-1 attenuates epidermal growth factor-dependent collagen loss in human carotid plaque smooth muscle cells

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 309, Issue 6, 2015, Pages H1075-H1086

  Rao, Velidi H ^a   Rai, Vikrant ^a   Stoupa, Samantha ^a   Agrawal, Devendra K ^a  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Carotid plaque; Collagen types I and III; Epidermal growth factor; Matrix metalloproteinases; V ets erythroblastosis virus E26 oncogene homologue 1; Vascular smooth muscle cells

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 4; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GELATINASE B; INTERSTITIAL COLLAGENASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR ETS 1; ETS1 PROTEIN, HUMAN; MMP1 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE;

ARTICLE; CAROTID ARTERY OBSTRUCTION; CAROTID ATHEROSCLEROSIS; CELL CYCLE S PHASE; CELL ISOLATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERSTITIUM; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE CELL; AGED; CULTURE TECHNIQUE; FEMALE; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; MIDDLE AGED; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

AGED; CAROTID STENOSIS; CELL CULTURE TECHNIQUES; COLLAGEN; EPIDERMAL GROWTH FACTOR; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 9; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEIN C-ETS-1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84941712482     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00378.2015     Document Type: Article

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