Glycosaminoglycan derivatives: promising candidates for the design of functional biomaterials

Journal of Materials Science: Materials in Medicine

Volumn 26, Issue 9, 2015, Pages

  Scharnweber, Dieter ^a   Hübner, Linda ^a   Rother, Sandra ^a   Hempel, Ute ^a   Anderegg, Ulf ^b   Samsonov, Sergey A ^a   Pisabarro, M Teresa ^a   Hofbauer, Lorenz ^c   Schnabelrauch, Matthias ^d   Franz, Sandra ^b   Simon, Jan ^b   Hintze, Vera ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^d Structural Bioinformatics BIOTEC TU Dresden ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL MEMBRANES; CELLS; CYTOLOGY; DENTAL PROSTHESES; ENZYME ACTIVITY; FIBROBLASTS; PROTEINS; TISSUE; TISSUE REGENERATION;

CELLULAR MICROENVIRONMENT; CHONDROITIN SULPHATE; FUNCTION RELATIONSHIPS; INTERACTION PROFILES; MESENCHYMAL STROMAL CELLS; NATIVE EXTRACELLULAR MATRIX; OSTEOGENIC DIFFERENTIATION; WOUND HEALING PROCESS;

PROCESS CONTROL;

BIOMATERIAL; CELL RECEPTOR; CHONDROITIN SULFATE; GLYCOSAMINOGLYCAN; HYALURONIC ACID DERIVATIVE; SCLEROPROTEIN;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; BONE DEVELOPMENT; BONE REGENERATION; CARBOHYDRATE ANALYSIS; CELL DIFFERENTIATION; CHEMICAL BINDING; CHEMICAL INTERACTION; DENDRITIC CELL; FIBROBLAST; HUMAN; HUMAN CELL; MACROPHAGE; MESENCHYMAL STROMA CELL; MINIPIG; MYOFIBROBLAST; NONHUMAN; OSTEOCLAST ACTIVITY; PRIORITY JOURNAL; PROTEIN INTERACTION; SKIN; SOLUTE; STRUCTURE ACTIVITY RELATION; SULFATION; TISSUE REGENERATION; TOOTH IMPLANT; WOUND HEALING; ANIMAL; ANIMAL MODEL; CHEMISTRY; EXTRACELLULAR MATRIX; METABOLISM; SURFACE PLASMON RESONANCE;

ANIMALS; BIOCOMPATIBLE MATERIALS; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; GLYCOSAMINOGLYCANS; HUMANS; MODELS, ANIMAL; SURFACE PLASMON RESONANCE;

EID: 84941644502     PISSN: 09574530     EISSN: 15734838     Source Type: Journal    
DOI: 10.1007/s10856-015-5563-7     Document Type: Article

References (41)

1. Lienemann PS, Lutolf MP, Ehrbar M. Biomimetic hydrogels for controlled biomolecule delivery to augment bone regeneration. Adv Drug Deliv Rev. 2012;64(12):1078–89. doi:10.1016/j.addr.2012.03.010.
2. Frantz C, Stewart KM, Weaver VM. The extracellular matrix at a glance. J Cell Sci. 2010;123(24):4195–200.
3. Salbach J, Rachner TD, Rauner M, Hempel U, Anderegg U, Franz S, et al. Regenerative potential of glycosaminoglycans for skin and bone. J Mol Med. 2012;90(6):625–35.
4. Gama CI, Hsieh-Wilson LC. Chemical approaches to deciphering the glycosaminoglycan code. Curr Opin Chem Biol. 2005;9(6):609–19.
5. Merceron C, Portron S, Vignes-Colombeix C, Rederstorff E, Masson M, Lesoeur J, et al. Pharmacological modulation of human mesenchymal stem cell chondrogenesis by a chemically oversulfated polysaccharide of marine origin: potential application to cartilage regenerative medicine. Stem Cells. 2012;30(3):471–80.
6. Pichert A, Schlorke D, Franz S, Arnhold J. Functional aspects of the interaction between interleukin-8 and sulfated glycosaminoglycans. Biomatter. 2012;2(3):142–8.
7. Lutolf MP, Blau HM. Artificial stem cell niches. Adv Mater. 2009;21(32–33):3255–68. doi:10.1002/adma.200802582.
8. Kliemt S, Lange C, Otto W, Hintze V, Möller S, von Bergen M, et al. Sulfated hyaluronan containing collagen matrices enhance cell-matrix-interaction, endocytosis, and osteogenic differentiation of human mesenchymal stromal cells. J Proteome Res. 2013;12(1):378–89. doi:10.1021/pr300640h.
9. Hintze V, Samsonov SA, Anselmi M, Moeller S, Becher J, Schnabelrauch M, et al. Sulfated glycosaminoglycans exploit the conformational plasticity of bone morphogenetic protein-2 (BMP-2) and alter the interaction profile with its receptor. Biomacromolecules. 2014;15(8):3083–92. doi:10.1021/bm5006855.
10. Schulz M, Korn P, Stadlinger B, Range U, Möller S, Becher J, et al. Coating with artificial matrices from collagen and sulfated hyaluronan influences the osseointegration of dental implants. J Mater Sci Mater Med. 2014;25(1):247–58. doi:10.1007/s10856-013-5066-3.
11. Salbach-Hirsch J, Kraemer J, Rauner M, Samsonov S, Pisabarro MT, Moeller S, et al. The promotion of osteoclastogenesis by sulfated hyaluronan through interference with osteoprotegerin and receptor activator of NF-κB ligand/osteoprotegerin complex formation. Biomaterials. 2013;34:7653–61.
12. Schiller J, Becher J, Möller S, Nimptsch K, Riemer T, Schnabelrauch M. Synthesis and characterization of chemically modified hyaluronan and chondroitin sulfate. Mini-Rev Org Chem. 2010;7(4):290–9.
13. Hintze V, Miron A, Moeller S, Schnabelrauch M, Wiesmann HP, Worch H, et al. Sulfated hyaluronan and chondroitin sulfate derivatives interact differently with human transforming growth factor-beta 1 (TGF-beta 1). Acta Biomater. 2012;8(6):2144–52.
14. Hintze V, Moeller S, Schnabelrauch M, Bierbaum S, Viola M, Worch H, et al. Modifications of hyaluronan influence the interaction with human bone morphogenetic protein-4 (hBMP-4). Biomacromolecules. 2009;10(12):3290–7.
15. Kunze R, Rösler M, Möller S, Schnabelrauch M, Riemer T, Hempel U, et al. Sulfated hyaluronan derivatives reduce the proliferation rate of primary rat calvarial osteoblasts. Glycoconj J. 2010;27(1):151–8.
16. van der Smissen A, Hintze V, Scharnweber D, Moeller S, Schnabelrauch M, Majok A, et al. Growth promoting substrates for human dermal fibroblasts provided by artificial extracellular matrices composed of collagen I and sulfated glycosaminoglycans. Biomaterials. 2011;32(34):8938–46.
17. Becher J, Möller S, Weiss D, Schiller J, Schnabelrauch M, editors. Synthesis of new regioselectively sulfated hyaluronans for biomedical application. Macromolecular symposia; 2010, Wiley Online Library.
18. Hempel U, Preissler C, Vogel S, Möller S, Hintze V, Becher J, et al. Artificial extracellular matrices with oversulfated glycosaminoglycan derivatives promote the differentiation of osteoblast-precursor cells and premature osteoblasts. Biomed Res Int. 2014. doi:10.1155/2014/934848.
19. Hempel U, Hintze V, Moller S, Schnabelrauch M, Scharnweber D, Dieter P. Artificial extracellular matrices composed of collagen I and sulfated hyaluronan with adsorbed transforming growth factor beta 1 promote collagen synthesis of human mesenchymal stromal cells. Acta Biomater. 2012;8(2):659–66. doi:10.1016/j.actbio.2011.10.026.
20. Hempel U, Moller S, Noack C, Hintze V, Scharnweber D, Schnabelrauch M, et al. Sulfated hyaluronan/collagen I matrices enhance the osteogenic differentiation of human mesenchymal stromal cells in vitro even in the absence of dexamethasone. Acta Biomater. 2012;8(11):4064–72.
21. Miron A, Rother S, Huebner L, Hempel U, Käppler I, Moeller S, et al. Sulfated hyaluronan influences the formation of artificial extracellular matrices and the adhesion of osteogenic cells. Macromol Biosci. 2014;14(12):1783–94.
22. Ruppert R, Hoffmann E, Sebald W. Human bone morphogenetic protein 2 contains a heparin-binding site which modifies its biological activity. Eur J Biochem. 1996;237(1):295–302.
23. Lyon M, Rushton G, Gallagher JT. The interaction of the transforming growth factor-βs with heparin/heparan sulfate is isoform-specific. J Biol Chem. 1997;272(29):18000–6.
24. Takada T, Katagiri T, Ifuku M, Morimura N, Kobayashi M, Hasegawa K, et al. Sulfated polysaccharides enhance the biological activities of bone morphogenetic proteins. J Biol Chem. 2003;278(44):43229–35.
25. Zhao B, Katagiri T, Toyoda H, Takada T, Yanai T, Fukuda T, et al. Heparin potentiates the in vivo ectopic bone formation induced by bone morphogenetic protein-2. J Biol Chem. 2006;281(32):23246–53.
26. Miyazaki T, Miyauchi S, Tawada A, Anada T, Matsuzaka S, Suzuki O. Oversulfated chondroitin sulfate-E binds to BMP-4 and enhances osteoblast differentiation. J Cell Physiol. 2008;217(3):769–77.
27. Kanzaki S, Takahashi T, Kanno T, Ariyoshi W, Shinmyouzu K, Tujisawa T, et al. Heparin inhibits BMP-2 osteogenic bioactivity by binding to both BMP-2 and BMP receptor. J Cell Physiol. 2008;216(3):844–50.
28. Salbach J, Kliemt S, Rauner M, Rachner TD, Goettsch C, Kalkhof S, et al. The effect of the degree of sulfation of glycosaminoglycans on osteoclast function and signaling pathways. Biomaterials. 2012;33(33):8418–29.
29. Salbach-Hirsch J, Ziegler N, Thiele S, Moeller S, Schnabelrauch M, Hintze V, et al. Sulfated glycosaminoglycans support osteoblast functions and concurrently suppress osteoclasts. J Cell Biochem. 2014;115(6):1101–11.
30. Franz S, Rammelt S, Scharnweber D, Simon J. Immune responses to implants—a review of the implications for the design of immunomodulatory biomaterials. Biomaterials. 2011;32(28):6692–709.
31. Acharya AP, Dolgova NV, Clare-Salzler MJ, Keselowsky BG. Adhesive substrate-modulation of adaptive immune responses. Biomaterials. 2008;29(36):4736–50.
32. Lutz MB, Schuler G. Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol. 2002;23(9):445–9.
33. Rutella S, Danese S, Leone G. Tolerogenic dendritic cells: cytokine modulation comes of age. Blood. 2006;108(5):1435–40.
34. Kajahn J, Franz S, Rueckert E, Forstreuter I, Hintze V, Moeller S, et al. Artificial extracellular matrices composed of collagen I and high sulfated hyaluronan modulate monocyte to macrophage differentiation under conditions of sterile inflammation. Biomatter. 2012;2(4):226–73.
35. Franz S, Allenstein F, Kajahn J, Forstreuter I, Hintze V, Möller S, et al. Artificial extracellular matrices composed of collagen I and high-sulfated hyaluronan promote phenotypic and functional modulation of human pro-inflammatory M1 macrophages. Acta Biomater. 2013;9(3):5621–9.
36. Hess R, Jaeschke A, Neubert H, Hintze V, Moeller S, Schnabelrauch M, et al. Synergistic effect of defined artificial extracellular matrices and pulsed electric fields on osteogenic differentiation of human MSCs. Biomaterials. 2012;33(35):8975–85.
37. Wojak-Cwik IM, Hintze V, Schnabelrauch M, Moeller S, Dobrzynski P, Pamula E, et al. Poly(L-lactide-co-glycolide) scaffolds coated with collagen and glycosaminoglycans: impact on proliferation and osteogenic differentiation of human mesenchymal stem cells. J Biomed Mater Res, Part A. 2013;101(11):3109–22. doi:10.1002/jbm.a.34620.
38. van der Smissen A, Samsonov S, Hintze V, Scharnweber D, Moeller S, Schnabelrauch M, et al. Artificial extracellular matrix composed of collagen I and highly sulfated hyaluronan interferes with TGFβ 1 signaling and prevents TGFβ 1-induced myofibroblast differentiation. Acta Biomater. 2013;9(8):7775–86.
39. Abe M, Harpel J, Metz C, Nunes I, Loskutoff D, Rifkin D. An assay for transforming growth factor-β using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Anal Biochem. 1994;216(2):276–84.
40. Heldin C-H, Miyazono K, Ten Dijke P. TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature. 1997;390(6659):465–71.
41. Korn P, Schulz M, Hintze V, Range U, Mai R, Eckelt U, et al. Chondroitin sulfate and sulfated hyaluronan-containing collagen coatings of titanium implants influence peri-implant bone formation in a minipig model. J Biomed Mater Res A. 2014;102(7):2334–44.