A systematic review on the applications of resting-state fMRI in Parkinson's disease: Does dopamine replacement therapy play a role?

Cortex

Volumn 73, Issue , 2015, Pages 80-105

  Tahmasian, Masoud ^a,b   Bettray, Lisa M ^a   van Eimeren, Thilo ^a   Drzezga, Alexander ^a   Timmermann, Lars ^a   Eickhoff, Claudia R ^c   Eickhoff, Simon B ^d,e   Eggers, Carsten ^a  

^a UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^b KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c RWTH AACHEN UNIVERSITY   (Germany)

^d HEINRICH HEINE UNIVERSITY   (Germany)

^e FORSCHUNGSZENTRUM JÜLICH   (Germany)

Author keywords

Dopamine replacement therapy; Functional connectivity; Parkinson's disease; Resting state fMRI

Indexed keywords

DOPAMINE; LEVODOPA;

BOLD SIGNAL; CAUDATE NUCLEUS; CEREBELLUM; DEFAULT MODE NETWORK; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GLOBUS PALLIDUS; HEAD MOVEMENT; HUMAN; MESENCEPHALON; OSCILLATION; PARIETAL CORTEX; PARKINSON DISEASE; PONS; POSTERIOR CINGULATE; PUTAMEN; RESTING STATE NETWORK; REVIEW; SYSTEMATIC REVIEW; THALAMUS; UNIFIED PARKINSON DISEASE RATING SCALE; ANIMAL; BRAIN; FUNCTIONAL NEUROIMAGING; METABOLISM; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PROCEDURES; TREATMENT OUTCOME;

ANIMALS; BRAIN; DOPAMINE; FUNCTIONAL NEUROIMAGING; HUMANS; MAGNETIC RESONANCE IMAGING; PARKINSON DISEASE; TREATMENT OUTCOME;

EID: 84941634695     PISSN: 00109452     EISSN: 19738102     Source Type: Journal    
DOI: 10.1016/j.cortex.2015.08.005     Document Type: Review

References (106)

1. Agosta F., Caso F., Stankovic I., Inuggi A., Petrovic I., Svetel M., et al. Cortico-striatal-thalamic network functional connectivity in hemiparkinsonism. Neurobiology of Aging 2014, 35(11):2592-2602. 10.1016/j.neurobiolaging.2014.05.032.
2. Alexander G.E., Crutcher M.D. Functional architecture of basal ganglia circuits: neural substrates of parallel processing. Trends in Neurosciences 1990, 13(7):266-271.
3. Amboni M., Tessitore A., Esposito F., Santangelo G., Picillo M., Vitale C., et al. Resting-state functional connectivity associated with mild cognitive impairment in Parkinson's disease. Journal of Neurology 2014, 262(2):425-434. 10.1007/s00415-014-7591-5.
4. Baggio H.C., Sala-Llonch R., Segura B., Marti M.J., Valldeoriola F., Compta Y., et al. Functional brain networks and cognitive deficits in Parkinson's disease. Human Brain Mapping 2014, 35(9):4620-4634. 10.1002/hbm.22499.
5. Baik K., Cha J., Ham J.H., Baek G.M., Sunwoo M.K., Hong J.Y., et al. Dopaminergic modulation of resting-state functional connectivity in de novo patients with Parkinson's disease. Human Brain Mapping 2014, 35(11):5431-5441. 10.1002/hbm.22561.
6. Baudrexel S., Witte T., Seifried C., von Wegner F., Beissner F., Klein J.C., et al. Resting state fMRI reveals increased subthalamic nucleus-motor cortex connectivity in Parkinson's disease. NeuroImage 2011, 55(4):1728-1738. 10.1016/j.neuroimage.2011.01.017.
7. Biswal B.B. Resting state fMRI: a personal history. NeuroImage 2012, 62(2):938-944. 10.1016/j.neuroimage.2012.01.090.
8. Biswal B., Yetkin F.Z., Haughton V.M., Hyde J.S. Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magnetic Resonance in Medicine 1995, 34(4):537-541.
9. Boeve B.F. REM sleep behavior disorder updated review of the core features, the REM sleep behavior disorder-neurodegenerative disease association, evolving concepts, controversies, and future directions. Year in Neurology 2010, 2(1184):15-54.
10. Braak H., Del Tredici K., Rub U., de Vos R.A., Jansen Steur E.N., Braak E. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiology of Aging 2003, 24(2):197-211.
11. Brown P. Oscillatory nature of human basal ganglia activity: relationship to the pathophysiology of Parkinson's disease. Movment Disorders 2003, 18(4):357-363. 10.1002/mds.10358.
12. Buckner R.L., Andrews-Hanna J.R., Schacter D.L. The brain's default network: anatomy, function, and relevance to disease. Annals of the New York Academy of Sciences 2008, 1124:1-38. 10.1196/annals.1440.011.
13. Calhoun V.D., Pekar J.J., McGinty V.B., Adali T., Watson T.D., Pearlson G.D. Different activation dynamics in multiple neural systems during simulated driving. Human Brain Mapping 2002, 16(3):158-167. 10.1002/hbm.10032.
14. Cerasa A., Gioia M.C., Salsone M., Donzuso G., Chiriaco C., Realmuto S., et al. Neurofunctional correlates of attention rehabilitation in Parkinson's disease: an explorative study. Neurological Sciences 2014, 35(8):1173-1180. 10.1007/s10072-014-1666-z.
15. Cerasa A., Koch G., Donzuso G., Mangone G., Morelli M., Brusa L., et al. A network centred on the inferior frontal cortex is critically involved in levodopa-induced dyskinesias. Brain 2014, 138(2):414-427. 10.1093/brain/awu329.
16. Choe I.H., Yeo S., Chung K.C., Kim S.H., Lim S. Decreased and increased cerebral regional homogeneity in early Parkinson's disease. Brain Research 2013, 1527:230-237. 10.1016/j.brainres.2013.06.027.
17. DeLong M.R. Primate models of movement disorders of basal ganglia origin. Trends in Neurosciences 1990, 13(7):281-285.
18. Disbrow E.A., Carmichael O., He J., Lanni K.E., Dressler E.M., Zhang L., et al. Resting state functional connectivity is associated with cognitive dysfunction in non-demented people with Parkinson's disease. Journal of Parkinson's Disease 2014, 4(3):453-465. 10.3233/JPD-130341.
19. Dukart J., Mueller K., Barthel H., Villringer A., Sabri O., Schroeter M.L., et al. Meta-analysis based SVM classification enables accurate detection of Alzheimer's disease across different clinical centers using FDG-PET and MRI. Psychiatry Research 2013, 212(3):230-236. 10.1016/j.pscychresns.2012.04.007.
20. Eckert T., Tang C., Eidelberg D. Assessment of the progression of Parkinson's disease: a metabolic network approach. The Lancet Neurology 2007, 6(10):926-932. 10.1016/S1474-4422(07)70245-4.
21. Eggers C., Schwartz F., Pedrosa D.J., Kracht L., Timmermann L. Parkinson's disease subtypes show a specific link between dopaminergic and glucose metabolism in the striatum. PLoS One 2014, 9(5). ARTN e96629. 10.1371/journal.pone.0096629.
22. Ellmore T.M., Castriotta R.J., Hendley K.L., Aalbers B.M., Furr-Stimming E., Hood A.J., et al. Altered nigrostriatal and nigrocortical functional connectivity in rapid eye movement sleep behavior disorder. Sleep 2013, 36(12):1885-1892. 10.5665/sleep.3222.
23. Esposito F., Tessitore A., Giordano A., De Micco R., Paccone A., Conforti R., et al. Rhythm-specific modulation of the sensorimotor network in drug-naive patients with Parkinson's disease by levodopa. Brain 2013, 136(Pt 3):710-725. 10.1093/brain/awt007.
24. Fling B.W., Cohen R.G., Mancini M., Carpenter S.D., Fair D.A., Nutt J.G., et al. Functional reorganization of the locomotor network in Parkinson patients with freezing of gait. PLoS One 2014, 9(6):e100291. 10.1371/journal.pone.0100291.
25. Fox M.D., Snyder A.Z., Vincent J.L., Corbetta M., Van Essen D.C., Raichle M.E. The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proceedings of the National Academy of Sciences of the United States of America 2005, 102(27):9673-9678. 10.1073/pnas.0504136102.
26. Fox M.D., Zhang D., Snyder A.Z., Raichle M.E. The global signal and observed anticorrelated resting state brain networks. Journal of Neurophysiology 2009, 101(6):3270-3283. 10.1152/jn.90777.2008.
27. Friston K.J. Functional and effective connectivity: a review. Brain Connectivity 2011, 1(1):13-36. 10.1089/brain.2011.0008.
28. Friston K.J., Williams S., Howard R., Frackowiak R.S., Turner R. Movement-related effects in fMRI time-series. Magnetic Resonance in Medicine 1996, 35(3):346-355.
29. Ghasemi M., Mahloojifar A. Disorganization of equilibrium directional interactions in the brain motor network of Parkinson's disease: new insight of resting state analysis using Granger causality and graphical approach. Journal of Medical Signals and Sensors 2013, 3(2):69-78.
30. Gorges M., Muller H.P., Lule D., Ludolph A.C., Pinkhardt E.H., Kassubek J. Functional connectivity within the default mode network is associated with saccadic accuracy in Parkinson's disease: a resting-state FMRI and videooculographic study. Brain Connectivity 2013, 3(3):265-272. 10.1089/brain.2013.0146.
31. Gottlich M., Munte T.F., Heldmann M., Kasten M., Hagenah J., Kramer U.M. Altered resting state brain networks in Parkinson's disease. PLoS One 2013, 8(10):e77336. 10.1371/journal.pone.0077336.
32. Hacker C.D., Perlmutter J.S., Criswell S.R., Ances B.M., Snyder A.Z. Resting state functional connectivity of the striatum in Parkinson's disease. Brain 2012, 135(Pt 12):3699-3711. 10.1093/brain/aws281.
33. Hart G., Leung B.K., Balleine B.W. Dorsal and ventral streams: the distinct role of striatal subregions in the acquisition and performance of goal-directed actions. Neurobiology of Learning and Memory 2014, 108:104-118. 10.1016/j.nlm.2013.11.003.
34. Helmich R.C., de Lange F.P., Bloem B.R., Toni I. Cerebral compensation during motor imagery in Parkinson's disease. Neuropsychologia 2007, 45(10):2201-2215. 10.1016/j.neuropsychologia.2007.02.024.
35. Helmich R.C., Derikx L.C., Bakker M., Scheeringa R., Bloem B.R., Toni I. Spatial remapping of cortico-striatal connectivity in Parkinson's disease. Cerebral Cortex 2010, 20(5):1175-1186. 10.1093/cercor/bhp178.
36. Helmich R.C., Janssen M.J., Oyen W.J., Bloem B.R., Toni I. Pallidal dysfunction drives a cerebellothalamic circuit into Parkinson tremor. Annals of Neurology 2011, 69(2):269-281. 10.1002/ana.22361.
37. Herz D.M., Eickhoff S.B., Lokkegaard A., Siebner H.R. Functional neuroimaging of motor control in Parkinson's disease: a meta-analysis. Human Brain Mapping 2014, 35(7):3227-3237. 10.1002/hbm.22397.
38. Hoptman M.J., Zuo X.N., Butler P.D., Javitt D.C., D'Angelo D., Mauro C.J., et al. Amplitude of low-frequency oscillations in schizophrenia: a resting state fMRI study. Schizophrenia Research 2010, 117(1):13-20. 10.1016/j.schres.2009.09.030.
39. Jankovic J. Parkinson's disease: clinical features and diagnosis. Journal of Neurology, Neurosurgery, Psychiatry 2008, 79(4):368-376. 10.1136/jnnp.2007.131045.
40. Kahan J., Urner M., Moran R., Flandin G., Marreiros A., Mancini L., et al. Resting state functional MRI in Parkinson's disease: the impact of deep brain stimulation on 'effective' connectivity. Brain 2014, 137(Pt 4):1130-1144. 10.1093/brain/awu027.
41. Kelly C., de Zubicaray G., Di Martino A., Copland D.A., Reiss P.T., Klein D.F., et al. L-dopa modulates functional connectivity in striatal cognitive and motor networks: a double-blind placebo-controlled study. Journal of Neuroscience 2009, 29(22):7364-7378. 10.1523/JNEUROSCI.0810-09.2009.
42. Klupp E., Forster S., Grimmer T., Tahmasian M., Yakushev I., Sorg C., et al. Alzheimer's disease, hypometabolism in low-amyloid brain regions may be a functional consequence of pathologies in connected brain regions. Brain Connectivity 2014, 4(5):371-383. 10.1089/brain.2013.0212.
43. Krajcovicova L., Mikl M., Marecek R., Rektorova I. The default mode network integrity in patients with Parkinson's disease is levodopa equivalent dose-dependent. Journal of Neural Transmission 2012, 119(4):443-454. 10.1007/s00702-011-0723-5.
44. Kurani A.S., Seidler R.D., Burciu R.G., Comella C.L., Corcos D.M., Okun M.S., et al. Subthalamic nucleus-sensorimotor cortex functional connectivity in de novo and moderate Parkinson's disease. Neurobiology of Aging 2014, 36(1):462-469. 10.1016/j.neurobiolaging.2014.07.004.
45. Kwak Y., Peltier S., Bohnen N.I., Muller M.L., Dayalu P., Seidler R.D. Altered resting state cortico-striatal connectivity in mild to moderate stage Parkinson's disease. Frontiers in Systems Neuroscience 2010, 4:143. 10.3389/fnsys.2010.00143.
46. Kwak Y., Peltier S.J., Bohnen N.I., Muller M.L., Dayalu P., Seidler R.D. L-DOPA changes spontaneous low-frequency BOLD signal oscillations in Parkinson's disease: a resting state fMRI study. Frontiers in Systems Neuroscience 2012, 6:52. 10.3389/fnsys.2012.00052.
47. Lebedev A.V., Westman E., Simmons A., Lebedeva A., Siepel F.J., Pereira J.B., et al. Large-scale resting state network correlates of cognitive impairment in Parkinson's disease and related dopaminergic deficits. Frontiers in Systems Neuroscience 2014, 8:45. 10.3389/fnsys.2014.00045.
48. Lehericy S., Sharman M.A., Dos Santos C.L., Paquin R., Gallea C. Magnetic resonance imaging of the substantia nigra in Parkinson's disease. Movement Disorders 2012, 27(7):822-830. 10.1002/mds.25015.
49. Liu H., Edmiston E.K., Fan G., Xu K., Zhao B., Shang X., et al. Altered resting-state functional connectivity of the dentate nucleus in Parkinson's disease. Psychiatry Research 2013, 211(1):64-71. 10.1016/j.pscychresns.2012.10.007.
50. Liu C.H., Li F., Li S.F., Wang Y.J., Tie C.L., Wu H.Y., et al. Abnormal baseline brain activity in bipolar depression: a resting state functional magnetic resonance imaging study. Psychiatry Research 2012, 203(2-3):175-179. 10.1016/j.pscychresns.2012.02.007.
51. Liu H., Liu Z., Liang M., Hao Y., Tan L., Kuang F., et al. Decreased regional homogeneity in schizophrenia: a resting state functional magnetic resonance imaging study. NeuroReport 2006, 17(1):19-22.
52. Liu Y., Wang K., Yu C., He Y., Zhou Y., Liang M., et al. Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: a review of resting-state fMRI studies. Neuropsychologia 2008, 46(6):1648-1656. 10.1016/j.neuropsychologia.2008.01.027.
53. Li Z., Zhu Y., Childress A.R., Detre J.A., Wang Z. Relations between BOLD fMRI-derived resting brain activity and cerebral blood flow. PLoS One 2012, 7(9):e44556. 10.1371/journal.pone.0044556.
54. Long D., Wang J., Xuan M., Gu Q., Xu X., Kong D., et al. Automatic classification of early Parkinson's disease with multi-modal MR imaging. PLoS One 2012, 7(11):e47714. 10.1371/journal.pone.0047714.
55. Luo C., Chen Q., Song W., Chen K., Guo X., Yang J., et al. Resting-state fMRI study on drug-naive patients with Parkinson's disease and with depression. Journal of Neurology, Neurosurgery, Psychiatry 2014, 85(6):675-683. 10.1136/jnnp-2013-306237.
56. Luo C., Song W., Chen Q., Zheng Z., Chen K., Cao B., et al. Reduced functional connectivity in early-stage drug-naive Parkinson's disease: a resting-state fMRI study. Neurobiology of Aging 2014, 35(2):431-441. 10.1016/j.neurobiolaging.2013.08.018.
57. Meng C., Brandl F., Tahmasian M., Shao J., Manoliu A., Scherr M., et al. Aberrant topology of striatum's connectivity is associated with the number of episodes in depression. Brain 2014, 137(Pt 2):598-609. 10.1093/brain/awt290.
58. Muller-Oehring E.M., Sullivan E.V., Pfefferbaum A., Huang N.C., Poston K.L., Bronte-Stewart H.M., et al. Task-rest modulation of basal ganglia connectivity in mild to moderate Parkinson's disease. Brain Imaging and Behavior 2014, 10.1007/s11682-014-9317-9.
59. Murphy K., Birn R.M., Handwerker D.A., Jones T.B., Bandettini P.A. The impact of global signal regression on resting state correlations: are anti-correlated networks introduced?. NeuroImage 2009, 44(3):893-905. 10.1016/j.neuroimage.2008.09.036.
60. Myers N., Pasquini L., Gottler J., Grimmer T., Koch K., Ortner M., et al. Within-patient correspondence of amyloid-beta and intrinsic network connectivity in Alzheimer's disease. Brain 2014, 137(7):2052-2064. 10.1093/brain/awu103.
61. Nutt J.G., Bloem B.R., Giladi N., Hallett M., Horak F.B., Nieuwboer A. Freezing of gait: moving forward on a mysterious clinical phenomenon. The Lancet, Neurology 2011, 10(8):734-744. 10.1016/S1474-4422(11)70143-0.
62. Olde Dubbelink K.T., Schoonheim M.M., Deijen J.B., Twisk J.W., Barkhof F., Berendse H.W. Functional connectivity and cognitive decline over 3 years in Parkinson disease. Neurology 2014, 83(22):2046-2053. 10.1212/WNL.0000000000001020.
63. Palmer S.J., Li J., Wang Z.J., McKeown M.J. Joint amplitude and connectivity compensatory mechanisms in Parkinson's disease. Neuroscience 2010, 166(4):1110-1118. 10.1016/j.neuroscience.2010.01.012.
64. Pasquini L., Scherr M., Tahmasian M., Meng C., Myers N.E., Ortner M., et al. Link between hippocampus' raised local and eased global intrinsic connectivity in AD. Alzheimer's Dementia 2014, 10.1016/j.jalz.2014.02.007.
65. Poston K.L., Eidelberg D. Functional brain networks and abnormal connectivity in the movement disorders. NeuroImage 2012, 62(4):2261-2270. 10.1016/j.neuroimage.2011.12.021.
66. Power J.D., Mitra A., Laumann T.O., Snyder A.Z., Schlaggar B.L., Petersen S.E. Methods to detect, characterize, and remove motion artifact in resting state fMRI. NeuroImage 2014, 84:320-341. 10.1016/j.neuroimage.2013.08.048.
67. Power J.D., Schlaggar B.L., Petersen S.E. Recent progress and outstanding issues in motion correction in resting state fMRI. NeuroImage 2015, 105:536-551. 10.1016/j.neuroimage.2014.10.044.
68. Prodoehl J., Burciu R.G., Vaillancourt D.E. Resting state functional magnetic resonance imaging in Parkinson's disease. Current Neurology and Neuroscience Reports 2014, 14(6):448. 10.1007/s11910-014-0448-6.
69. Pyatigorskaya N., Gallea C., Garcia-Lorenzo D., Vidailhet M., Lehericy S. A review of the use of magnetic resonance imaging in Parkinson's disease. Therapeutic Advances in Neurological Disorders 2014, 7(4):206-220. 10.1177/1756285613511507.
70. Ravina B., Camicioli R., Como P.G., Marsh L., Jankovic J., Weintraub D., et al. The impact of depressive symptoms in early Parkinson disease. Neurology 2007, 69(4):342-347. 10.1212/01.wnl.0000268695.63392.10.
71. Rektorova I., Krajcovicova L., Marecek R., Mikl M. Default mode network and extrastriate visual resting state network in patients with Parkinson's disease dementia. Neurodegenerative Diseases 2012, 10(1-4):232-237. 10.1159/000334765.
72. Rubinov M., Sporns O. Complex network measures of brain connectivity: uses and interpretations. NeuroImage 2010, 52(3):1059-1069. 10.1016/j.neuroimage.2009.10.003.
73. Salat D., Tolosa E. Levodopa in the treatment of Parkinson's disease: current status and new developments. Journal of Parkinson's Disease 2013, 3(3):255-269. 10.3233/JPD-130186.
74. Sharman M., Valabregue R., Perlbarg V., Marrakchi-Kacem L., Vidailhet M., Benali H., et al. Parkinson's disease patients show reduced cortical-subcortical sensorimotor connectivity. Movement Disorders 2013, 28(4):447-454. 10.1002/mds.25255.
75. Sheng K., Fang W., Su M., Li R., Zou D., Han Y., et al. Altered spontaneous brain activity in patients with Parkinson's disease accompanied by depressive symptoms, as revealed by regional homogeneity and functional connectivity in the prefrontal-limbic system. PLoS One 2014, 9(1):e84705. 10.1371/journal.pone.0084705.
76. Shine J.M., Halliday G.M., Gilat M., Matar E., Bolitho S.J., Carlos M., et al. The role of dysfunctional attentional control networks in visual misperceptions in Parkinson's disease. Human Brain Mapping 2014, 35(5):2206-2219. 10.1002/hbm.22321.
77. Skidmore F.M., Yang M., Baxter L., von Deneen K., Collingwood J., He G., et al. Apathy, depression, and motor symptoms have distinct and separable resting activity patterns in idiopathic Parkinson disease. NeuroImage 2013, 81:484-495. 10.1016/j.neuroimage.2011.07.012.
78. Skidmore F.M., Yang M., Baxter L., von Deneen K.M., Collingwood J., He G., et al. Reliability analysis of the resting state can sensitively and specifically identify the presence of Parkinson disease. NeuroImage 2013, 75:249-261. 10.1016/j.neuroimage.2011.06.056.
79. Snyder A.Z., Raichle M.E. A brief history of the resting state: the Washington University perspective. NeuroImage 2012, 62(2):902-910. 10.1016/j.neuroimage.2012.01.044.
80. Stephan K.E., Friston K.J. Analyzing effective connectivity with fMRI. Wiley in Interdisciplinary Reviews. Cognitive Sciences 2010, 1(3):446-459. 10.1002/wcs.58.
81. Stoessl A.J. Functional imaging studies of non-motoric manifestations of Parkinson's disease. Parkinsonism & Related Disorders 2009, 15(Suppl. 3):S13-S16. 10.1016/S1353-8020(09)70771-0.
82. Stoessl A.J., Martin W.W., McKeown M.J., Sossi V. Advances in imaging in Parkinson's disease. The Lancet. Neurology 2011, 10(11):987-1001. 10.1016/S1474-4422(11)70214-9.
83. Szewczyk-Krolikowski K., Menke R.A., Rolinski M., Duff E., Salimi-Khorshidi G., Filippini N., et al. Functional connectivity in the basal ganglia network differentiates PD patients from controls. Neurology 2014, 83(3):208-214. 10.1212/WNL.0000000000000592.
84. Tahmasian M., Knight D.C., Manoliu A., Schwerthoffer D., Scherr M., Meng C., et al. Aberrant intrinsic connectivity of hippocampus and amygdala overlap in the fronto-insular and dorsomedial-prefrontal cortex in major depressive disorder. Frontiers in Human Neurosciences 2013, 7:639. 10.3389/fnhum.2013.00639.
85. Tahmasian M., Pasquini L., Scherr M., Meng C., Forster S., Mulej Bratec S., et al. The lower hippocampus global connectivity, the higher its local metabolism in Alzheimer disease. Neurology 2015, 84(19):1956-1963. 10.1212/WNL.0000000000001575.
86. Tessitore A., Amboni M., Esposito F., Russo A., Picillo M., Marcuccio L., et al. Resting-state brain connectivity in patients with Parkinson's disease and freezing of gait. Parkinsonism & Related Disorders 2012, 18(6):781-787. 10.1016/j.parkreldis.2012.03.018.
87. Tessitore A., Esposito F., Vitale C., Santangelo G., Amboni M., Russo A., et al. Default-mode network connectivity in cognitively unimpaired patients with Parkinson disease. Neurology 2012, 79(23):2226-2232. 10.1212/WNL.0b013e31827689d6.
88. Tuite P.J., Mangia S., Michaeli S. Magnetic resonance imaging (MRI) in Parkinson's disease. Journal of Alzheimers Disease Parkinsonism 2013, 001(Suppl. 1). 10.4172/2161-0460.S1-001.
89. Van Dijk K.R., Sabuncu M.R., Buckner R.L. The influence of head motion on intrinsic functional connectivity MRI. NeuroImage 2012, 59(1):431-438. 10.1016/j.neuroimage.2011.07.044.
90. Wang J., Zuo X., He Y. Graph-based network analysis of resting-state functional MRI. Frontiers in Systems Neuroscience 2010, 4:16. 10.3389/fnsys.2010.00016.
91. Ward P., Seri, Cavanna A.E. Functional neuroanatomy and behavioural correlates of the basal ganglia: evidence from lesion studies. Behavioural Neurology 2013, 26(4):219-223. 10.3233/BEN-2012-120264.
92. Weissenbacher A., Kasess C., Gerstl F., Lanzenberger R., Moser E., Windischberger C. Correlations and anticorrelations in resting-state functional connectivity MRI: a quantitative comparison of preprocessing strategies. NeuroImage 2009, 47(4):1408-1416. 10.1016/j.neuroimage.2009.05.005.
93. Wei L., Zhang J., Long Z., Wu G.R., Hu X., Zhang Y., et al. Reduced topological efficiency in cortical-basal Ganglia motor network of Parkinson's disease: a resting state fMRI study. PLoS One 2014, 9(10):e108124. 10.1371/journal.pone.0108124.
94. Wen X., Wu X., Liu J., Li K., Yao L. Abnormal baseline brain activity in non-depressed Parkinson's disease and depressed Parkinson's disease: a resting-state functional magnetic resonance imaging study. PLoS One 2013, 8(5):e63691. 10.1371/journal.pone.0063691.
95. Willis A.W. Parkinson disease in the elderly adult. Missouri Medicine 2013, 110(5):406-410.
96. Wu T., Long X., Wang L., Hallett M., Zang Y., Li K., et al. Functional connectivity of cortical motor areas in the resting state in Parkinson's disease. Human Brain Mapping 2011, 32(9):1443-1457. 10.1002/hbm.21118.
97. Wu T., Long X., Zang Y., Wang L., Hallett M., Li K., et al. Regional homogeneity changes in patients with Parkinson's disease. Human Brain Mapping 2009, 30(5):1502-1510. 10.1002/hbm.20622.
98. Wu T., Wang L., Chen Y., Zhao C., Li K., Chan P. Changes of functional connectivity of the motor network in the resting state in Parkinson's disease. Neuroscience Letters 2009, 460(1):6-10. 10.1016/j.neulet.2009.05.046.
99. Wu T., Wang J., Wang C., Hallett M., Zang Y., Wu X., et al. Basal ganglia circuits changes in Parkinson's disease patients. Neuroscience Letters 2012, 524(1):55-59. 10.1016/j.neulet.2012.07.012.
100. Yang H., Zhou X.J., Zhang M.M., Zheng X.N., Zhao Y.L., Wang J. Changes in spontaneous brain activity in early Parkinson's disease. Neuroscience Letters 2013, 549:24-28. 10.1016/j.neulet.2013.05.080.
101. Yao N., S.-K.C.R., Cheung C., Pang S., Lau K.K., Suckling J., et al. The default mode network is disrupted in parkinson's disease with visual hallucinations. Human Brain Mapping 2014, 35(11):5658-5666. 10.1002/hbm.22577.
102. Yu R., Liu B., Wang L., Chen J., Liu X. Enhanced functional connectivity between putamen and supplementary motor area in Parkinson's disease patients. PLoS One 2013, 8(3):e59717. 10.1371/journal.pone.0059717.
103. Zang Y., Jiang T., Lu Y., He Y., Tian L. Regional homogeneity approach to fMRI data analysis. NeuroImage 2004, 22(1):394-400. 10.1016/j.neuroimage.2003.12.030.
104. Zhang D., Wang Y., Zhou L., Yuan H., Shen D., Alzheimer's Disease Neuroimaging, Initiative Multimodal classification of Alzheimer's disease and mild cognitive impairment. NeuroImage 2011, 55(3):856-867. 10.1016/j.neuroimage.2011.01.008.
105. Zhang J., Wei L., Hu X., Zhang Y., Zhou D., Li C., et al. Specific frequency band of amplitude low-frequency fluctuation predicts Parkinson's disease. Behavioural Brain Research 2013, 252:18-23. 10.1016/j.bbr.2013.05.039.
106. Zou Q.H., Zhu C.Z., Yang Y., Zuo X.N., Long X.Y., Cao Q.J., et al. An improved approach to detection of amplitude of low-frequency fluctuation (ALFF) for resting-state fMRI: fractional ALFF. Journal of Neurosciences Methods 2008, 172(1):137-141. 10.1016/j.jneumeth.2008.04.012.