메뉴 건너뛰기




Volumn 54, Issue 10, 2015, Pages 1051-1059

Upregulation of KLF4 by methylseleninic acid in human esophageal squamous cell carcinoma cells: Modification of histone H3 acetylation through HAT/HDAC interplay

Author keywords

GCN5; Histone acetylation; KLF4; Selenium

Indexed keywords

CASPASE 3; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE GCN5; HISTONE DEACETYLASE; HISTONE H3; KRUPPEL LIKE FACTOR 4; MESSENGER RNA; METHYLSELENINIC ACID; SELENIC ACID; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WATER; HISTONE; KRUPPEL LIKE FACTOR; METHYLSELENIC ACID; ORGANOSELENIUM DERIVATIVE;

EID: 84941616980     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22174     Document Type: Article
Times cited : (33)

References (53)
  • 1
    • 33646876823 scopus 로고    scopus 로고
    • Dietary selenium intake, aldehyde dehydrogenase-2 and X-ray repair cross-complementing 1 genetic polymorphisms, and the risk of esophageal squamous cell carcinoma
    • Cai L, You NC, Lu H, et al. Dietary selenium intake, aldehyde dehydrogenase-2 and X-ray repair cross-complementing 1 genetic polymorphisms, and the risk of esophageal squamous cell carcinoma. Cancer 2006; 106:2345-2354.
    • (2006) Cancer , vol.106 , pp. 2345-2354
    • Cai, L.1    You, N.C.2    Lu, H.3
  • 2
    • 2442622507 scopus 로고    scopus 로고
    • A prospective study of plasma selenium levels and prostate cancer risk
    • Li H, Stampfer MJ, Giovannucci EL, et al. A prospective study of plasma selenium levels and prostate cancer risk. J Natl Cancer Inst 2004; 96:696-703.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 696-703
    • Li, H.1    Stampfer, M.J.2    Giovannucci, E.L.3
  • 3
    • 58149383852 scopus 로고    scopus 로고
    • Effect of selenium and vitamin E on risk of prostate cancer and other cancers: The Selenium and Vitamin E Cancer Prevention Trial (SELECT)
    • Lippman SM, Klein EA, Goodman PJ, et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: The Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 2009; 301:39-51.
    • (2009) JAMA , vol.301 , pp. 39-51
    • Lippman, S.M.1    Klein, E.A.2    Goodman, P.J.3
  • 4
    • 0034332627 scopus 로고    scopus 로고
    • Prospective study of serum selenium levels and incident esophageal and gastric cancers
    • Mark SD, Qiao YL, Dawsey SM, et al. Prospective study of serum selenium levels and incident esophageal and gastric cancers. J Natl Cancer Inst 2000; 92:1753-1763.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1753-1763
    • Mark, S.D.1    Qiao, Y.L.2    Dawsey, S.M.3
  • 5
    • 24144475928 scopus 로고    scopus 로고
    • Randomized, placebo-controlled, esophageal squamous cell cancer chemoprevention trial of selenomethionine and celecoxib
    • Limburg PJ, Wei W, Ahnen DJ, et al. Randomized, placebo-controlled, esophageal squamous cell cancer chemoprevention trial of selenomethionine and celecoxib. Gastroenterology 2005; 129:863-873.
    • (2005) Gastroenterology , vol.129 , pp. 863-873
    • Limburg, P.J.1    Wei, W.2    Ahnen, D.J.3
  • 6
    • 84873290591 scopus 로고    scopus 로고
    • Post SELECT selenium on trial
    • Sharma AK, Amin S. Post SELECT selenium on trial. Future Med Chem 2013; 5:163-174.
    • (2013) Future Med Chem , vol.5 , pp. 163-174
    • Sharma, A.K.1    Amin, S.2
  • 7
    • 47249097092 scopus 로고    scopus 로고
    • Superior in vivo inhibitory efficacy of methylseleninic acid against human prostate cancer over selenomethionine or selenite
    • Li GX, Lee HJ, Wang Z, et al. Superior in vivo inhibitory efficacy of methylseleninic acid against human prostate cancer over selenomethionine or selenite. Carcinogenesis 2008; 29:1005-1012.
    • (2008) Carcinogenesis , vol.29 , pp. 1005-1012
    • Li, G.X.1    Lee, H.J.2    Wang, Z.3
  • 8
    • 0034214376 scopus 로고    scopus 로고
    • In vitro and in vivo studies of methylseleninic acid: Evidence that a monomethylated selenium metabolite is critical for cancer chemoprevention
    • Ip C, Thompson HJ, Zhu Z, Ganther HE. In vitro and in vivo studies of methylseleninic acid: Evidence that a monomethylated selenium metabolite is critical for cancer chemoprevention. Cancer Res 2000; 60:2882-2886.
    • (2000) Cancer Res , vol.60 , pp. 2882-2886
    • Ip, C.1    Thompson, H.J.2    Zhu, Z.3    Ganther, H.E.4
  • 9
    • 77954757417 scopus 로고    scopus 로고
    • beta-Catenin/TCF pathway plays a vital role in selenium induced-growth inhibition and apoptosis in esophageal squamous cell carcinoma (ESCC) cells
    • Zhang W, Yan S, Liu M, et al. beta-Catenin/TCF pathway plays a vital role in selenium induced-growth inhibition and apoptosis in esophageal squamous cell carcinoma (ESCC) cells. Cancer Lett 2010; 296:113-122.
    • (2010) Cancer Lett , vol.296 , pp. 113-122
    • Zhang, W.1    Yan, S.2    Liu, M.3
  • 10
    • 67650318995 scopus 로고    scopus 로고
    • Methyl-selenium compounds inhibit prostate carcinogenesis in the transgenic adenocarcinoma of mouse prostate model with survival benefit
    • Wang L, Bonorden MJ, Li GX, et al. Methyl-selenium compounds inhibit prostate carcinogenesis in the transgenic adenocarcinoma of mouse prostate model with survival benefit. Cancer Prev Res (Phila) 2009; 2:484-495.
    • (2009) Cancer Prev Res (Phila) , vol.2 , pp. 484-495
    • Wang, L.1    Bonorden, M.J.2    Li, G.X.3
  • 11
    • 36749042560 scopus 로고    scopus 로고
    • Methylseleninic acid inhibits microvascular endothelial G1 cell cycle progression and decreases tumor microvessel density
    • Wang Z, Hu H, Li G, et al. Methylseleninic acid inhibits microvascular endothelial G1 cell cycle progression and decreases tumor microvessel density. Int J Cancer 2008; 122:15-24.
    • (2008) Int J Cancer , vol.122 , pp. 15-24
    • Wang, Z.1    Hu, H.2    Li, G.3
  • 13
    • 0030798245 scopus 로고    scopus 로고
    • Histone acetylation in chromatin structure and transcription
    • Grunstein M. Histone acetylation in chromatin structure and transcription. Nature 1997; 389:349-352.
    • (1997) Nature , vol.389 , pp. 349-352
    • Grunstein, M.1
  • 14
    • 0032467010 scopus 로고    scopus 로고
    • Signaling to chromatin through histone modifications: How clear is the signal
    • Mizzen C, Kuo MH, Smith E, et al. Signaling to chromatin through histone modifications: How clear is the signal? Cold Spring Harb Symp Quant Biol 1998; 63:469-481.
    • (1998) Cold Spring Harb Symp Quant Biol , vol.63 , pp. 469-481
    • Mizzen, C.1    Kuo, M.H.2    Smith, E.3
  • 15
    • 6044256118 scopus 로고    scopus 로고
    • Histones and histone modifications
    • Peterson CL, Laniel MA. Histones and histone modifications. Curr Biol 2004; 14:R546-R551.
    • (2004) Curr Biol , vol.14 , pp. R546-R551
    • Peterson, C.L.1    Laniel, M.A.2
  • 16
    • 74849127193 scopus 로고    scopus 로고
    • Epigenetic therapy: Histone acetylation, DNA methylation and anti-cancer drug discovery
    • Ganesan A, Nolan L, Crabb SJ, Packham G. Epigenetic therapy: Histone acetylation, DNA methylation and anti-cancer drug discovery. Curr Cancer Drug Targets 2009; 9:963-981.
    • (2009) Curr Cancer Drug Targets , vol.9 , pp. 963-981
    • Ganesan, A.1    Nolan, L.2    Crabb, S.J.3    Packham, G.4
  • 17
    • 56049083256 scopus 로고    scopus 로고
    • Selenite reactivates silenced genes by modifying DNA methylation and histones in prostate cancer cells
    • Xiang N, Zhao R, Song G, Zhong W. Selenite reactivates silenced genes by modifying DNA methylation and histones in prostate cancer cells. Carcinogenesis 2008; 29:2175-2181.
    • (2008) Carcinogenesis , vol.29 , pp. 2175-2181
    • Xiang, N.1    Zhao, R.2    Song, G.3    Zhong, W.4
  • 19
    • 11844282202 scopus 로고    scopus 로고
    • Overexpression of human pituitary tumor transforming gene (hPTTG), is regulated by beta-catenin/TCF pathway in human esophageal squamous cell carcinoma
    • Zhou C, Liu S, Zhou X, et al. Overexpression of human pituitary tumor transforming gene (hPTTG), is regulated by beta-catenin/TCF pathway in human esophageal squamous cell carcinoma. Int J Cancer 2005; 113:891-898.
    • (2005) Int J Cancer , vol.113 , pp. 891-898
    • Zhou, C.1    Liu, S.2    Zhou, X.3
  • 20
    • 69549116658 scopus 로고    scopus 로고
    • Methylselenol, a selenium metabolite, induces cell cycle arrest in G1 phase and apoptosis via the extracellular-regulated kinase 1/2 pathway and other cancer signaling genes
    • Zeng H, Wu M, Botnen JH. Methylselenol, a selenium metabolite, induces cell cycle arrest in G1 phase and apoptosis via the extracellular-regulated kinase 1/2 pathway and other cancer signaling genes. J Nutr 2009; 139:1613-1618.
    • (2009) J Nutr , vol.139 , pp. 1613-1618
    • Zeng, H.1    Wu, M.2    Botnen, J.H.3
  • 21
    • 0029835806 scopus 로고    scopus 로고
    • Transcription-linked acetylation by Gcn5p of histones H3 and H4 at specific lysines
    • Kuo MH, Brownell JE, Sobel RE, et al. Transcription-linked acetylation by Gcn5p of histones H3 and H4 at specific lysines. Nature 1996; 383:269-272.
    • (1996) Nature , vol.383 , pp. 269-272
    • Kuo, M.H.1    Brownell, J.E.2    Sobel, R.E.3
  • 22
    • 40349102090 scopus 로고    scopus 로고
    • Kruppel-like factor 4 is a novel mediator of selenium in growth inhibition
    • Liu S, Zhang H, Zhu L, Zhao L, Dong Y. Kruppel-like factor 4 is a novel mediator of selenium in growth inhibition. Mol Cancer Res 2008; 6:306-313.
    • (2008) Mol Cancer Res , vol.6 , pp. 306-313
    • Liu, S.1    Zhang, H.2    Zhu, L.3    Zhao, L.4    Dong, Y.5
  • 23
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell 2007; 128:693-705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 24
    • 77952936173 scopus 로고    scopus 로고
    • Redox signaling, alkylation (carbonylation) of conserved cysteines inactivates class I histone deacetylases 1, 2 and 3 and antagonizes their transcriptional repressor function
    • Doyle K, Fitzpatrick FA. Redox signaling, alkylation (carbonylation) of conserved cysteines inactivates class I histone deacetylases 1, 2 and 3 and antagonizes their transcriptional repressor function. J Biol Chem 2010; 285:17417-17424.
    • (2010) J Biol Chem , vol.285 , pp. 17417-17424
    • Doyle, K.1    Fitzpatrick, F.A.2
  • 25
    • 69249166677 scopus 로고    scopus 로고
    • Alpha-keto acid metabolites of naturally occurring organoselenium compounds as inhibitors of histone deacetylase in human prostate cancer cells
    • Lee JI, Nian H, Cooper AJ, et al. Alpha-keto acid metabolites of naturally occurring organoselenium compounds as inhibitors of histone deacetylase in human prostate cancer cells. Cancer Prev Res (Phila) 2009; 2:683-693.
    • (2009) Cancer Prev Res (Phila) , vol.2 , pp. 683-693
    • Lee, J.I.1    Nian, H.2    Cooper, A.J.3
  • 26
    • 69449083759 scopus 로고    scopus 로고
    • Alpha-keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells
    • Nian H, Bisson WH, Dashwood WM, Pinto JT, Dashwood RH. Alpha-keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells. Carcinogenesis 2009; 30:1416-1423.
    • (2009) Carcinogenesis , vol.30 , pp. 1416-1423
    • Nian, H.1    Bisson, W.H.2    Dashwood, W.M.3    Pinto, J.T.4    Dashwood, R.H.5
  • 27
    • 84860238020 scopus 로고    scopus 로고
    • Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells
    • Rajendran P, Ho E, Williams DE, Dashwood RH. Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells. Clin Epigenetics 2011; 3:4.
    • (2011) Clin Epigenetics , vol.3 , pp. 4
    • Rajendran, P.1    Ho, E.2    Williams, D.E.3    Dashwood, R.H.4
  • 28
    • 84887136759 scopus 로고    scopus 로고
    • Which form is that? The importance of selenium speciation and metabolism in the prevention and treatment of disease
    • Weekley CM, Harris HH. Which form is that? The importance of selenium speciation and metabolism in the prevention and treatment of disease. Chem Soc Rev 2013; 42:8870-8894.
    • (2013) Chem Soc Rev , vol.42 , pp. 8870-8894
    • Weekley, C.M.1    Harris, H.H.2
  • 29
    • 0029984469 scopus 로고    scopus 로고
    • Tetrahymena histone acetyltransferase A: A homolog to yeast Gcn5p linking histone acetylation to gene activation
    • Brownell JE, Zhou J, Ranalli T, et al. Tetrahymena histone acetyltransferase A: A homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell 1996; 84:843-851.
    • (1996) Cell , vol.84 , pp. 843-851
    • Brownell, J.E.1    Zhou, J.2    Ranalli, T.3
  • 30
    • 67650409769 scopus 로고    scopus 로고
    • Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells
    • Tjeertes JV, Miller KM, Jackson SP. Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. EMBO J 2009; 28:1878-1889.
    • (2009) EMBO J , vol.28 , pp. 1878-1889
    • Tjeertes, J.V.1    Miller, K.M.2    Jackson, S.P.3
  • 31
    • 78751611793 scopus 로고    scopus 로고
    • Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation
    • Jin Q, Yu LR, Wang L, et al. Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation. EMBO J 2011; 30:249-262.
    • (2011) EMBO J , vol.30 , pp. 249-262
    • Jin, Q.1    Yu, L.R.2    Wang, L.3
  • 33
    • 84875243579 scopus 로고    scopus 로고
    • Akt kinase targets the association of CBP with histone H3 to regulate the acetylation of lysine K18
    • Liu Y, Xing ZB, Zhang JH, Fang Y. Akt kinase targets the association of CBP with histone H3 to regulate the acetylation of lysine K18. FEBS Lett 2013; 587:847-853.
    • (2013) FEBS Lett , vol.587 , pp. 847-853
    • Liu, Y.1    Xing, Z.B.2    Zhang, J.H.3    Fang, Y.4
  • 34
    • 84862102070 scopus 로고    scopus 로고
    • E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin kappa locus
    • Sakamoto S, Wakae K, Anzai Y, et al. E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin kappa locus. J Immunol 2012; 188:5547-5560.
    • (2012) J Immunol , vol.188 , pp. 5547-5560
    • Sakamoto, S.1    Wakae, K.2    Anzai, Y.3
  • 35
    • 1842582972 scopus 로고    scopus 로고
    • Kruppel-like factor 4 is transactivated by butyrate in colon cancer cells
    • Chen ZY, Rex S, Tseng CC. Kruppel-like factor 4 is transactivated by butyrate in colon cancer cells. J Nutr 2004; 134:792-798.
    • (2004) J Nutr , vol.134 , pp. 792-798
    • Chen, Z.Y.1    Rex, S.2    Tseng, C.C.3
  • 36
    • 70449095895 scopus 로고    scopus 로고
    • Kruppel-like factor 4 mediates histone deacetylase inhibitor-induced prevention of cardiac hypertrophy
    • Kee HJ, Kook H. Kruppel-like factor 4 mediates histone deacetylase inhibitor-induced prevention of cardiac hypertrophy. J Mol Cell Cardiol 2009; 47:770-780.
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 770-780
    • Kee, H.J.1    Kook, H.2
  • 37
    • 0038676409 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase activity by butyrate
    • Davie JR. Inhibition of histone deacetylase activity by butyrate. J Nutr 2003; 133:2485S-2493S.
    • (2003) J Nutr , vol.133 , pp. 2485S-2493S
    • Davie, J.R.1
  • 38
    • 84863556840 scopus 로고    scopus 로고
    • Trichostatin A prevents neointimal hyperplasia via activation of Kruppel like factor 4
    • Kee HJ, Kwon JS, Shin S, Ahn Y, Jeong MH, Kook H. Trichostatin A prevents neointimal hyperplasia via activation of Kruppel like factor 4. Vascul Pharmacol 2011; 55:127-134.
    • (2011) Vascul Pharmacol , vol.55 , pp. 127-134
    • Kee, H.J.1    Kwon, J.S.2    Shin, S.3    Ahn, Y.4    Jeong, M.H.5    Kook, H.6
  • 39
    • 46249112085 scopus 로고    scopus 로고
    • Combinatorial patterns of histone acetylations and methylations in the human genome
    • Wang Z, Zang C, Rosenfeld JA, et al. Combinatorial patterns of histone acetylations and methylations in the human genome. Nat Genet 2008; 40:897-903.
    • (2008) Nat Genet , vol.40 , pp. 897-903
    • Wang, Z.1    Zang, C.2    Rosenfeld, J.A.3
  • 40
    • 34547890019 scopus 로고    scopus 로고
    • Functions of site-specific histone acetylation and deacetylation
    • Shahbazian MD, Grunstein M. Functions of site-specific histone acetylation and deacetylation. Annu Rev Biochem 2007; 76:75-100.
    • (2007) Annu Rev Biochem , vol.76 , pp. 75-100
    • Shahbazian, M.D.1    Grunstein, M.2
  • 41
    • 77957551870 scopus 로고    scopus 로고
    • A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
    • Li R, Liang J, Ni S, et al. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell 2010; 7:51-63.
    • (2010) Cell Stem Cell , vol.7 , pp. 51-63
    • Li, R.1    Liang, J.2    Ni, S.3
  • 42
    • 77956320116 scopus 로고    scopus 로고
    • Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming
    • Samavarchi-Tehrani P, Golipour A, David L, et al. Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell 2010; 7:64-77.
    • (2010) Cell Stem Cell , vol.7 , pp. 64-77
    • Samavarchi-Tehrani, P.1    Golipour, A.2    David, L.3
  • 43
    • 30144440248 scopus 로고    scopus 로고
    • The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene
    • Rowland BD, Bernards R, Peeper DS. The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene. Nat Cell Biol 2005; 7:1074-1082.
    • (2005) Nat Cell Biol , vol.7 , pp. 1074-1082
    • Rowland, B.D.1    Bernards, R.2    Peeper, D.S.3
  • 44
    • 79955608022 scopus 로고    scopus 로고
    • Kruppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion
    • Yu F, Li J, Chen H, et al. Kruppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion. Oncogene 2011; 30:2161-2172.
    • (2011) Oncogene , vol.30 , pp. 2161-2172
    • Yu, F.1    Li, J.2    Chen, H.3
  • 45
    • 68949093614 scopus 로고    scopus 로고
    • KLF4 suppresses estrogen-dependent breast cancer growth by inhibiting the transcriptional activity of ERalpha
    • Akaogi K, Nakajima Y, Ito I, et al. KLF4 suppresses estrogen-dependent breast cancer growth by inhibiting the transcriptional activity of ERalpha. Oncogene 2009; 28:2894-2902.
    • (2009) Oncogene , vol.28 , pp. 2894-2902
    • Akaogi, K.1    Nakajima, Y.2    Ito, I.3
  • 47
    • 16844386207 scopus 로고    scopus 로고
    • Drastic down-regulation of Kruppel-like factor 4 expression is critical in human gastric cancer development and progression
    • Wei D, Gong W, Kanai M, et al. Drastic down-regulation of Kruppel-like factor 4 expression is critical in human gastric cancer development and progression. Cancer Res 2005; 65:2746-2754.
    • (2005) Cancer Res , vol.65 , pp. 2746-2754
    • Wei, D.1    Gong, W.2    Kanai, M.3
  • 48
    • 0037780740 scopus 로고    scopus 로고
    • Overexpression of Kruppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenecity
    • Dang DT, Chen X, Feng J, Torbenson M, Dang LH, Yang VW. Overexpression of Kruppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenecity. Oncogene 2003; 22:3424-3430.
    • (2003) Oncogene , vol.22 , pp. 3424-3430
    • Dang, D.T.1    Chen, X.2    Feng, J.3    Torbenson, M.4    Dang, L.H.5    Yang, V.W.6
  • 49
    • 78650318077 scopus 로고    scopus 로고
    • Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration
    • Wang J, Place RF, Huang V, et al. Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration. Cancer Res 2010; 70:10182-10191.
    • (2010) Cancer Res , vol.70 , pp. 10182-10191
    • Wang, J.1    Place, R.F.2    Huang, V.3
  • 50
    • 79960065994 scopus 로고    scopus 로고
    • Kruppel-like factor 4 inhibits tumorigenic progression and metastasis in a mouse model of breast cancer
    • Yori JL, Seachrist DD, Johnson E, et al. Kruppel-like factor 4 inhibits tumorigenic progression and metastasis in a mouse model of breast cancer. Neoplasia 2011; 13:601-610.
    • (2011) Neoplasia , vol.13 , pp. 601-610
    • Yori, J.L.1    Seachrist, D.D.2    Johnson, E.3
  • 51
    • 84862777918 scopus 로고    scopus 로고
    • Disruption of Klf4 in villin-positive gastric progenitor cells promotes formation and progression of tumors of the antrum in mice
    • Li Q, Jia Z, Wang L, et al. Disruption of Klf4 in villin-positive gastric progenitor cells promotes formation and progression of tumors of the antrum in mice. Gastroenterology 2012; 142:531-542.
    • (2012) Gastroenterology , vol.142 , pp. 531-542
    • Li, Q.1    Jia, Z.2    Wang, L.3
  • 52
    • 70349441108 scopus 로고    scopus 로고
    • Putative tumor-suppressive function of Kruppel-like factor 4 in primary lung carcinoma
    • Hu W, Hofstetter WL, Li H, et al. Putative tumor-suppressive function of Kruppel-like factor 4 in primary lung carcinoma. Clin Cancer Res 2009; 15:5688-5695.
    • (2009) Clin Cancer Res , vol.15 , pp. 5688-5695
    • Hu, W.1    Hofstetter, W.L.2    Li, H.3
  • 53
    • 4344635044 scopus 로고    scopus 로고
    • Identification of aberrantly methylated genes in association with adult T-cell leukemia
    • Yasunaga J, Taniguchi Y, Nosaka K, et al. Identification of aberrantly methylated genes in association with adult T-cell leukemia. Cancer Res 2004; 64:6002-6009.
    • (2004) Cancer Res , vol.64 , pp. 6002-6009
    • Yasunaga, J.1    Taniguchi, Y.2    Nosaka, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.