Akt kinase targets the association of CBP with histone H3 to regulate the acetylation of lysine K18

FEBS Letters

Volumn 587, Issue 7, 2013, Pages 847-853

  Liu, Yan ^a   Xing, Zhao Bin ^a   Zhang, Jing Hua ^b   Fang, Yue ^c  

^a HEBEI UNITED UNIVERSITY   (China)

^b TANGSHAN PEOPLE S HOSPITAL   (China)

^c Beijing Bohaitongda Bio Tech Co Ltd   (China)

Author keywords

Acetylation; Akt; CBP

Indexed keywords

ACYLTRANSFERASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HISTONE H3; LYSINE; PROTEIN KINASE B; THREONINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CANCER GROWTH; CARCINOGENESIS; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME REGULATION; ENZYME SUBSTRATE COMPLEX; GENE TARGETING; HELA CELL; HISTONE ACETYLATION; HUMAN; HUMAN CELL; MALIGNANT NEOPLASTIC DISEASE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

ACETYLATION; ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; CREB-BINDING PROTEIN; GENE EXPRESSION PROFILING; HELA CELLS; HISTONE ACETYLTRANSFERASES; HISTONES; HUMANS; LYSINE; MCF-7 CELLS; MICE; MICE, NUDE; MUTATION; NEOPLASMS, EXPERIMENTAL; PHOSPHORYLATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; SUBSTRATE SPECIFICITY; THREONINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 84875243579     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.02.023     Document Type: Article

References (22)

1. T.F. Franke, S.I. Yang, T.O. Chan, K. Datta, A. Kazlauskas, and D.K. Morrison The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase Cell 81 1995 727 736
2. A. Toker Achieving specificity in Akt signaling in cancer Adv. Enzyme Regul. 52 2011 78 87
3. J. Luo, B.D. Manning, and L.C. Cantley Targeting the PI3K-Akt pathway in human cancer: rationale and promise Cancer Cell 4 2003 257 262
4. Manning B.D. and Cantley L.C. (2002) Hitting the target: emerging technologies in the search for kinase substrates. Sci. STKE. 2002,PE49.
5. B.D. Manning, and L.C. Cantley AKT/PKB signaling: navigating downstream Cell 129 2007 1261 1274
6. Moritz A.; Li Y.; Guo A.; Villen J.; Wang Y.; MacNeill J et al. (2010) Akt-RSK-S6 kinase signaling networks activated by oncogenic receptor tyrosine kinases. Sci. Signal. 3, ra64.
7. T. Kouzarides Chromatin modifications and their function Cell 128 2007 693 705
8. R. Chari, K.L. Thu, I.M. Wilson, W.W. Lockwood, K.M. Lonergan, and B.P. Coe Integrating the multiple dimensions of genomic and epigenomic landscapes of cancer Cancer Metastasis Rev. 29 2010 73 93
9. D.B. Seligson, S. Horvath, M.A. McBrian, V. Mah, and H. Yu Global levels of histone modifications predict prognosis in different cancers Am. J. Pathol. 174 2009 1619 1628
10. M.F. Fraga, E. Ballestar, A. Villar-Garea, M. Boix-Chornet, J. Espada, and G. Schotta Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer Nat. Genet. 37 2005 391 400
11. T.L. Cha, B.P. Zhou, W. Xia, Y. Wu, C.C. Yang, and C.T. Chen Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3 Science 310 2005 306 310
12. D.B. Seligson, S. Horvath, M.A. McBrian, V. Mah, H. Yu, and S. Tze Global levels of histone modifications predict prognosis in different cancers Am. J. Pathol. 174 2009 1619 1628
13. M.F. Fraga, E. Ballestar, A. Villar-Garea, M. Boix-Chornet, J. Espada, and G. Schotta Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer Nat. Genet. 37 2005 391 400
14. G.A. Horwitz, K. Zhang, M.A. McBrian, M. Grunstein, S.K. Kurdistani, and A.J. Berk Adenovirus small e1a alters global patterns of histone modification Science 321 2008 1084 1085
15. C.D. Allis, S.L. Berger, J. Cote, S. Dent, T. Jenuwien, and T. Kouzarides New nomenclature for chromatin-modifying enzymes Cell 131 2007 633 636
16. M.F. Barber, E. Michishita-Kioi, Y. Xi, L. Tasselli, M. Kioi, and Z. Moqtaderi SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation Nature 487 2012 114 120
17. N.G. Iyer, H. Özdag, and C. Caldas P300/CBP and cancer Oncogene 23 2004 4225 4231
18. B.P. Zhou, Y. Liao, W. Xia, B. Spohn, M.H. Lee, and M.C. Huang Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells Nat. Cell Biol. 3 2001 245 252
19. W.C. Huang, and C.C. Chen Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity Mol. Cell. Biol. 25 2005 6592 6602
20. D.R. Alessi, F.B. Caudwell, M. Andjelkovic, B.A. Hemmings, and P. Cohen Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase FEBS Lett. 399 1996 333 338
21. A. Carnero The PKB/Akt pathway in cancer Curr. Pharm. Des. 16 2010 34 44
22. Xuan C.; Wang Q.; Han X.; Duan Y.; Li L.; Shi L et al. (2012) RBB, a novel transcription repressor, represses the transcription of HDM2 oncogene. Oncogene. (e-pub ahead of print 27 August 2012). http://dx.doi.org/10.1038/onc. 2012.386