Global transcriptomic profiling of cardiac hypertrophy and fatty heart induced by long-term high-energy diet in bama miniature pigs

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Xia, Jihan ^a   Zhang, Yuanyuan ^b   Xin, Leilei ^a   Kong, Siyuan ^a   Chen, Yaoxing ^b   Yang, Shulin ^a   Li, Kui ^a  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ALPHA ACTININ 2; CD74 ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FIBROBLAST GROWTH FACTOR RECEPTOR 1; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; STAT3 PROTEIN;

ACSL4 GENE; ACTN2 GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATF4 GENE; BAMA MINIATURE PIG; CALORIC INTAKE; CD74 GENE; CONTROLLED STUDY; DOWN REGULATION; FADD GENE; FATTY ACID METABOLISM; FEMALE; FGFR1 GENE; GENE; GENE EXPRESSION REGULATION; HEART VENTRICLE HYPERTROPHY; HEART VOLUME; MALE; MICROARRAY ANALYSIS; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PPP3CA GENE; SIGNAL TRANSDUCTION; SLA 8 GENE; STAT3 GENE; STEATOSIS; TRANSCRIPTOMICS; UPREGULATION; VCL GENE; WEIGHT GAIN; ADVERSE EFFECTS; ANIMAL; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CARDIOMEGALY; CLUSTER ANALYSIS; COMPLICATION; DNA MICROARRAY; DYSLIPIDEMIA; GENE EXPRESSION PROFILING; GENE ONTOLOGY; GENETICS; LIPID DIET; METABOLISM; MINIPIG; OBESITY; PATHOLOGY; PIG; REAL TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY; STAINING; TIME FACTOR;

ANIMALS; CARDIOMEGALY; CLUSTER ANALYSIS; DIET, HIGH-FAT; DYSLIPIDEMIAS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE ONTOLOGY; MALE; MYOCARDIUM; MYOCYTES, CARDIAC; OBESITY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REAL-TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; STAINING AND LABELING; SWINE; SWINE, MINIATURE; TIME FACTORS;

EID: 84941588335     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0132420     Document Type: Article

References (40)

1. Mottillo S, Filion KB, Genest J, Joseph L, Pilote L, Poirier P, et al. (2010) The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis. J Am Coll Cardiol 56: 1113-1132. doi:10.1016/j.jacc.2010.05.034PMID: 20863953.
2. Chess DJ, Stanley WC (2008) Role of diet and fuel overabundance in the development and progression of heart failure. Cardiovasc Res 79: 269-278. doi:10.1093/cvr/cvn074 PMID: 18343896.
3. Shimabukuro M (2009) Cardiac adiposity and global cardiometabolic risk: new concept and clinical implication. Circ J 73: 27-34. PMID: 19057089.
4. Graner M, Siren R, Nyman K, Lundbom J, Hakkarainen A, Pentikainen MO, et al. (2013) Cardiac steatosis associates with visceral obesity in nondiabetic obese men. J Clin Endocrinol Metab 98: 1189- 1197. doi:10.1210/jc.2012-3190 PMID: 23418318.
5. Brindley DN, Kok BP, Kienesberger PC, Lehner R, Dyck JR (2010) Shedding light on the enigma of myocardial lipotoxicity: The involvement of known and putative regulators of fatty acid storage and mobilization. Am J Physiol Endocrinol Metab 298: E897-E908. doi:10.1152/ajpendo.00509.2009 PMID: 20103741.
6. Guzzardi MA, Iozzo P (2011) Fatty heart, cardiac damage, and inflammation. Rev Diabet Stud 8: 403- 417. doi:10.1900/RDS.2011.8.403 PMID: 22262077.
7. Iozzo P (2011) Myocardial, perivascular, and epicardial fat. Diabetes Care 34 Suppl 2: S371-S379. doi:10.2337/dc11-s250PMID:21525485.
8. Giacco F, Brownlee M (2010) Oxidative stress and diabetic complications. Circ Res 107: 1058-1070. doi:10.1161/CIRCRESAHA.110.223545PMID: 21030723.
9. Schenk S, Saberi M, Olefsky JM (2008) Insulin sensitivity: modulation by nutrients and inflammation. J Clin Invest 118: 2992-3002. doi:10.1172/JCI34260 PMID: 18769626.
10. Franchini KG, Clemente CF, Marin TM (2009) Focal adhesion kinase signaling in cardiac hypertrophy and failure. Braz J Med Biol Res 42: 44-52. PMID: 19219296.
11. Osterholt M, Nguyen TD, Schwarzer M, Doenst T (2013) Alterations in mitochondrial function in cardiac hypertrophy and heart failure. Heart Fail Rev 18: 645-656. doi:10.1007/s10741-012-9346-7 PMID: 22968404.
12. Spurlock ME, Gabler NK (2008) The development of porcine models of obesity and the metabolic syndrome. J Nutr 138: 397-402. PMID: 18203910.
13. Xia J, Hu B, Mu Y, Xin L, Yang S, Li K (2014) Molecular cloning and characterization of the promoter region of the porcine apolipoprotein E gene. Mol Biol Rep 41: 3211-3217. doi:10.1007/s11033-014-3182-xPMID: 24464129.
14. Xia J, Yuan J, Xin L, Zhang Y, Kong S, Chen Y, et al. (2014) Transcriptome analysis on the inflammatory cell infiltration of nonalcoholic steatohepatitis in bama minipigs induced by a long-term high-fat, high-sucrose diet. PLoS One 9: E113724. doi:10.1371/journal.pone.0113724 PMID: 25415189.
15. Berenji K, Drazner MH, Rothermel BA, Hill JA (2005) Does load-induced ventricular hypertrophy progress to systolic heart failure? Am J Physiol Heart Circ Physiol 289: H8-H16. PMID: 15961379.
16. Peterson LR, Herrero P, Schechtman KB, Racette SB, Waggoner AD, Kisrieva-Ware Z, et al. (2004) Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women. Circulation 109: 2191-2196. PMID: 15123530.
17. Rodrigues B, Cam MC, McNeill JH (1998) Metabolic disturbances in diabetic cardiomyopathy. Mol Cell Biochem 180: 53-57. PMID: 9546630.
18. Bell DS (2007) Heart failure in the diabetic patient. Cardiol Clin 25: 523-538; vi. PMID: 18063157.
19. Stanley WC, Recchia FA, Lopaschuk GD (2005) Myocardial substrate metabolism in the normal and failing heart. Physiol Rev 85: 1093-1129. PMID: 15987803.
20. Molkentin JD (2004) Calcineurin-NFAT signaling regulates the cardiac hypertrophic response in coordination with the MAPKs. Cardiovasc Res 63: 467-475. PMID: 15276472.
21. Gupta S, Das B, Sen S (2007) Cardiac hypertrophy: mechanisms and therapeutic opportunities. Antioxid Redox Signal 9: 623-652. PMID: 17511580.
22. Richard AF, Demignon J, Sakakibara I, Pujol J, Favier M, Strochlic L, et al. (2011) Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression. Dev Biol 359: 303-320. doi:10.1016/j.ydbio.2011.08.010 PMID: 21884692.
23. Xiao L, Zhu X, Yang S, Liu F, Zhou Z, Zhan M, et al. (2014) Rap1 ameliorates renal tubular injury in diabetic nephropathy. Diabetes 63: 1366-1380 doi:10.2337/db13-1412 PMID: 24353183.
24. Kim HJ, Kim JG, Moon MY, Park SH, Park JB (2014) IkappaB kinase gamma/nuclear factor-kappaBessential modulator (IKKgamma/NEMO) facilitates RhoA GTPase activation, which, in turn, activates Rho-associated KINASE (ROCK) to phosphorylate IKKbeta in response to transforming growth factor (TGF)-beta1. J Biol Chem 289: 1429-1440. doi:10.1074/jbc.M113.520130 PMID: 24240172.
25. Chan CP, Kok KH, Tang HM, Wong CM, Jin DY (2013) Internal ribosome entry site-mediated translational regulation of ATF4 splice variant in mammalian unfolded protein response. Biochim Biophys Acta 1833: 2165-2175. doi:10.1016/j.bbamcr.2013.05.002 PMID: 23665047.
26. Madsen K, Reddy RN, Price SR, Williams CR, Gooch JL (2013) Nutritional intervention restores muscle but not kidney phenotypes in adult calcineurin Aalpha null mice. PLoS One 8: E62503. doi:10.1371/journal.pone.0062503 PMID: 23638102.
27. Abdulsid A, Fletcher A, Lyall F (2013) Heat shock protein 27 is spatially distributed in the human placenta and decreased during labor. PLoS One 8: E71127. doi:10.1371/journal.pone.0071127 PMID: 23990930.
28. Malchers F, Dietlein F, Schottle J, Lu X, Nogova L, Albus K, et al. (2014) Cell-autonomous and noncell- Autonomous mechanisms of transformation by amplified FGFR1 in lung cancer. Cancer Discov 4: 246-257. doi:10.1158/2159-8290.CD-13-0323 PMID: 24302556.
29. Hsia HC, Nair MR, Corbett SA (2014) The fate of internalized alpha5 integrin is regulated by matrixcapable fibronectin. J Surg Res 191: 268-279. doi:10.1016/j.jss.2014.05.084 PMID: 25062814.
30. Chiu C, Bagnall RD, Ingles J, Yeates L, Kennerson M, Donald JA, et al. (2010) Mutations in alpha-actinin- 2 cause hypertrophic cardiomyopathy: A genome-wide analysis. J Am Coll Cardiol 55: 1127-1135. doi:10.1016/j.jacc.2009.11.016 PMID: 20022194.
31. Bays JL, Peng X, Tolbert CE, Guilluy C, Angell AE, Pan Y, et al. (2014) Vinculin phosphorylation differentially regulates mechanotransduction at cell-cell and cell-matrix adhesions. J Cell Biol 205: 251-263. doi:10.1083/jcb.201309092 PMID: 24751539.
32. Weterman MA, Barth PG, van-Spaendonck-Zwarts KY, Aronica E, Poll-The BT, Brouwer OF, et al. (2013) Recessive MYL2 mutations cause infantile type I muscle fibre disease and cardiomyopathy. Brain 136: 282-293. doi:10.1093/brain/aws293 PMID: 23365102.
33. Ong RW, AlSaman A, Selcen D, Arabshahi A, Yau KS, Ravenscroft G, et al. (2014) Novel cofilin-2 (CFL2) four base pair deletion causing nemaline myopathy. J Neurol Neurosurg Psychiatry 85: 1058- 1060. doi:10.1136/jnnp-2014-307608 PMID: 24610938.
34. Baumgarten G, Knuefermann P, Kalra D, Gao F, Taffet GE, Michael L, et al. (2002) Load-dependent and-independent regulation of proinflammatory cytokine and cytokine receptor gene expression in the adult mammalian heart. Circulation 105: 2192-2197 PMID: 11994254.
35. Yue L, Xie J, Nattel S (2011) Molecular determinants of cardiac fibroblast electrical function and therapeutic implications for atrial fibrillation. Cardiovasc Res 89: 744-753doi:10.1093/cvr/cvq329PMID: 20962103.
36. Kusza S, Flori L, Gao Y, Teillaud A, Hu R, Lemonnier G, et al. (2011) Transcription specificity of the class Ib genes SLA-6, SLA-7 and SLA-8 of the swine major histocompatibility complex and comparison with class Ia genes. Anim Genet 42: 510-520. doi:10.1111/j.1365-2052.2010.02170.x PMID: 21906102.
37. Zhang H, Liu C, Cheng S, Wang X, Li W, Charreyre C, et al. (2013) Porcine CD74 is involved in the inflammatory response activated by nuclear factor kappa B during porcine circovirus type 2 (PCV-2) infection. Arch Virol 158: 2285-2295. doi:10.1007/s00705-013-1750-3 PMID: 23736979.
38. Barbisan F, Savio C, Bertorelle G, Patarnello T, Congiu L (2009) Duplication polymorphism at MHC class II DRB1 locus in the wild boar (Sus scrofa). Immunogenetics 61: 145-151. doi:10.1007/s00251-008-0339-6PMID: 18987853.
39. Shim J, Seo H, Choi Y, Yoo I, Lee CK, Hyun SH, et al. (2013) Analysis of legumain and cystatin 6 expression at the maternal-fetal interface in pigs. Mol Reprod Dev 80: 570-580. doi:10.1002/mrd.22192PMID: 23686917.
40. Song G, Bailey DW, Dunlap KA, Burghardt RC, Spencer TE, Bazer FW, et al. (2010) Cathepsin B, cathepsin L, and cystatin C in the porcine uterus and placenta: potential roles in endometrial/placental remodeling and in fluid-phase transport of proteins secreted by uterine epithelia across placental areolae. Biol Reprod 82: 854-864. doi:10.1095/biolreprod.109.080929 PMID: 20107207.