메뉴 건너뛰기




Volumn 47, Issue 8, 2015, Pages 630-638

MiR-181a-5p inhibits cell proliferation and migration by targeting Kras in non-small cell lung cancer A549 cells

Author keywords

Migration; MiR 181a 5p; Non small cell lung cancer; Proliferation

Indexed keywords

KRAS PROTEIN, HUMAN; MICRORNA; MIRN181 MICRORNA, HUMAN; PROTEIN P21;

EID: 84941565930     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1093/abbs/gmv054     Document Type: Article
Times cited : (70)

References (35)
  • 3
    • 84886085558 scopus 로고    scopus 로고
    • MicroRNAs as lung cancer biomarkers and key players in lung carcinogenesis
    • Vannini I, Fanini F, Fabbri M. MicroRNAs as lung cancer biomarkers and key players in lung carcinogenesis. Clin Biochem 2013, 46: 918-925
    • (2013) Clin Biochem , vol.46 , pp. 918-925
    • Vannini, I.1    Fanini, F.2    Fabbri, M.3
  • 4
    • 84878173440 scopus 로고    scopus 로고
    • MiR-150, p53 protein and relevant miRNAs consist of a regulatory network in NSCLC tumorigenesis
    • Wang DT, Ma ZL, Li YL, Wang YQ, Zhao BT, Wei JL, Qiu X, et al. miR-150, p53 protein and relevant miRNAs consist of a regulatory network in NSCLC tumorigenesis. Oncol Rep 2013, 30: 492-498
    • (2013) Oncol Rep , vol.30 , pp. 492-498
    • Wang, D.T.1    Ma, Z.L.2    Li, Y.L.3    Wang, Y.Q.4    Zhao, B.T.5    Wei, J.L.6    Qiu, X.7
  • 5
    • 84920973525 scopus 로고    scopus 로고
    • Sputum microRNA biomarkers for identifying lung cancer in indeterminate solitary pulmonary nodules
    • Xing L, Su J, Guarnera MA, Zhang H, Cai L, Zhou R, Stass SA, et al. Sputum microRNA biomarkers for identifying lung cancer in indeterminate solitary pulmonary nodules. Clin Cancer Res 2015, 21: 484-489
    • (2015) Clin Cancer Res , vol.21 , pp. 484-489
    • Xing, L.1    Su, J.2    Guarnera, M.A.3    Zhang, H.4    Cai, L.5    Zhou, R.6    Stass, S.A.7
  • 6
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005, 120: 15-20
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 8
    • 84881014054 scopus 로고    scopus 로고
    • The role of microRNAs in lung cancer progression
    • Zhang WC, Liu J, Xu X, Wang G. The role of microRNAs in lung cancer progression. Med Oncol 2013, 30: 675
    • (2013) Med Oncol , vol.30 , pp. 675
    • Zhang, W.C.1    Liu, J.2    Xu, X.3    Wang, G.4
  • 10
    • 62249137047 scopus 로고    scopus 로고
    • Role of miR-143 targeting KRAS in colorectal tumorigenesis
    • Chen X, Guo X, Zhang H, Xiang Y, Chen J, Yin Y, Cai X, et al. Role of miR-143 targeting KRAS in colorectal tumorigenesis. Oncogene 2009, 28: 1385-1392
    • (2009) Oncogene , vol.28 , pp. 1385-1392
    • Chen, X.1    Guo, X.2    Zhang, H.3    Xiang, Y.4    Chen, J.5    Yin, Y.6    Cai, X.7
  • 11
    • 79954468469 scopus 로고    scopus 로고
    • MicroRNAs in kidneys: Biogenesis, regulation, and pathophysiological roles
    • Bhatt K, Mi QS, Dong Z. microRNAs in kidneys: biogenesis, regulation, and pathophysiological roles. Am J Physiol Renal Physiol 2011, 300: F602-F610
    • (2011) Am J Physiol Renal Physiol , vol.300 , pp. F602-F610
    • Bhatt, K.1    Mi, Q.S.2    Dong, Z.3
  • 13
    • 84899897538 scopus 로고    scopus 로고
    • MicroRNA-181a promotes tumor growth and liver metastasis in colorectal cancer by targeting the tumor suppressor WIF-1
    • Ji DB, Chen ZG, Li M, Zhan TC, Yao YF, Zhang ZQ, Xi JZ, et al. MicroRNA-181a promotes tumor growth and liver metastasis in colorectal cancer by targeting the tumor suppressor WIF-1. Mol Cancer 2014, 13: 86
    • (2014) Mol Cancer , vol.13 , pp. 86
    • Ji, D.B.1    Chen, Z.G.2    Li, M.3    Zhan, T.C.4    Yao, Y.F.5    Zhang, Z.Q.6    Xi, J.Z.7
  • 14
    • 84906084606 scopus 로고    scopus 로고
    • MiR-181a-5p is downregulated in hepatocellular carcinoma and suppresses motility, invasion and branching-morphogenesis by directly targeting c-Met
    • Korhan P, Erdal E, Atabey N. miR-181a-5p is downregulated in hepatocellular carcinoma and suppresses motility, invasion and branching-morphogenesis by directly targeting c-Met. Biochem Biophys Res Commun 2014, 450: 1304-1312
    • (2014) Biochem Biophys Res Commun , vol.450 , pp. 1304-1312
    • Korhan, P.1    Erdal, E.2    Atabey, N.3
  • 16
    • 84911363513 scopus 로고    scopus 로고
    • Clinical significance of up-regulated miR-181a in prognosis and progression of esophageal cancer
    • Xiang Z, Dong X, Sun Q, Li X, Yan B. Clinical significance of up-regulated miR-181a in prognosis and progression of esophageal cancer. Acta Biochim Biophys Sin 2014, 46: 1007-1010
    • (2014) Acta Biochim Biophys Sin , vol.46 , pp. 1007-1010
    • Xiang, Z.1    Dong, X.2    Sun, Q.3    Li, X.4    Yan, B.5
  • 17
    • 84921647799 scopus 로고    scopus 로고
    • MicroRNA-30d and microRNA-181a regulate HOXA11 expression in the uterosacral ligaments and are overexpressed in pelvic organ prolapse
    • Jeon MJ, Kim EJ, Lee M, Kim H, Choi JR, Chae HD, Moon YJ, et al. MicroRNA-30d and microRNA-181a regulate HOXA11 expression in the uterosacral ligaments and are overexpressed in pelvic organ prolapse. J Cell Mol Med 2015, 19: 501-509
    • (2015) J Cell Mol Med , vol.19 , pp. 501-509
    • Jeon, M.J.1    Kim, E.J.2    Lee, M.3    Kim, H.4    Choi, J.R.5    Chae, H.D.6    Moon, Y.J.7
  • 18
    • 84919430025 scopus 로고    scopus 로고
    • Targeted anticancer effect through microRNA-181a regulated tumor-specific hTERT replacement
    • Won YS, Jeong JS, Kim SJ, Ju MH, Lee SW. Targeted anticancer effect through microRNA-181a regulated tumor-specific hTERT replacement. Cancer Lett 2015, 356: 918-928
    • (2015) Cancer Lett , vol.356 , pp. 918-928
    • Won, Y.S.1    Jeong, J.S.2    Kim, S.J.3    Ju, M.H.4    Lee, S.W.5
  • 20
    • 77951658161 scopus 로고    scopus 로고
    • KRAS mutant lung cancer cells are differentially responsive to MEK inhibitor due to AKT or STAT3 activation: Implication for combinatorial approach
    • Yoon YK, Kim HP, Han SW, Oh do Y, Im SA, Bang YJ, Kim TY. KRAS mutant lung cancer cells are differentially responsive to MEK inhibitor due to AKT or STAT3 activation: implication for combinatorial approach. Mol Carcinog 2010, 49: 353-362
    • (2010) Mol Carcinog , vol.49 , pp. 353-362
    • Yoon, Y.K.1    Kim, H.P.2    Han, S.W.3    Oh Do, Y.4    Im, S.A.5    Bang, Y.J.6    Kim, T.Y.7
  • 21
    • 84859487222 scopus 로고    scopus 로고
    • Increased Ras GTPase activity is regulated by miRNAs that can be attenuated by CDF treatment in pancreatic cancer cells
    • Ali S, Ahmad A, Aboukameel A, Bao B, Padhye S, Philip PA, Sarkar FH. Increased Ras GTPase activity is regulated by miRNAs that can be attenuated by CDF treatment in pancreatic cancer cells. Cancer Lett 2012, 319: 173-181
    • (2012) Cancer Lett , vol.319 , pp. 173-181
    • Ali, S.1    Ahmad, A.2    Aboukameel, A.3    Bao, B.4    Padhye, S.5    Philip, P.A.6    Sarkar, F.H.7
  • 23
    • 84935520556 scopus 로고    scopus 로고
    • MicroRNA-34a inhibits the proliferation and promotes the apoptosis of non-small cell lung cancer H1299 cell line by targeting TGFbetaR2
    • Ma ZL, Hou PP, Li YL, Wang DT, Yuan TW, Wei JL, Zhao BT, et al. MicroRNA-34a inhibits the proliferation and promotes the apoptosis of non-small cell lung cancer H1299 cell line by targeting TGFbetaR2. Tumour Biol 2014, 36: 2481-2490
    • (2014) Tumour Biol , vol.36 , pp. 2481-2490
    • Ma, Z.L.1    Hou, P.P.2    Li, Y.L.3    Wang, D.T.4    Yuan, T.W.5    Wei, J.L.6    Zhao, B.T.7
  • 24
    • 84904341854 scopus 로고    scopus 로고
    • Mega roles of micro-RNAs in regulation of skeletal muscle health and disease
    • Sharma M, Juvvuna PK, Kukreti H, McFarlane C. Mega roles of micro-RNAs in regulation of skeletal muscle health and disease. Front Physiol 2014, 5: 239
    • (2014) Front Physiol , vol.5 , pp. 239
    • Sharma, M.1    Juvvuna, P.K.2    Kukreti, H.3    McFarlane, C.4
  • 25
    • 79953128406 scopus 로고    scopus 로고
    • Roles for microRNAs in the regulation of cell adhesion molecules
    • Valastyan S, Weinberg RA. Roles for microRNAs in the regulation of cell adhesion molecules. J Cell Sci 2011, 124: 999-1006
    • (2011) J Cell Sci , vol.124 , pp. 999-1006
    • Valastyan, S.1    Weinberg, R.A.2
  • 26
    • 79960069397 scopus 로고    scopus 로고
    • Impaired microRNA processing facilitates breast cancer cell invasion by upregulating urokinase-type plasminogen activator expression
    • Noh H, Hong S, Dong Z, Pan ZK, Jing Q, Huang S. Impaired microRNA processing facilitates breast cancer cell invasion by upregulating urokinase-type plasminogen activator expression. Genes Cancer 2011, 2: 140-150
    • (2011) Genes Cancer , vol.2 , pp. 140-150
    • Noh, H.1    Hong, S.2    Dong, Z.3    Pan, Z.K.4    Jing, Q.5    Huang, S.6
  • 28
    • 84868136612 scopus 로고    scopus 로고
    • MicroRNA-181a promotes gastric cancer by negatively regulating tumor suppressor KLF6
    • Zhang X, Nie Y, Du Y, Cao J, Shen B, Li Y. MicroRNA-181a promotes gastric cancer by negatively regulating tumor suppressor KLF6. Tumour Biol 2012, 33: 1589-1597
    • (2012) Tumour Biol , vol.33 , pp. 1589-1597
    • Zhang, X.1    Nie, Y.2    Du, Y.3    Cao, J.4    Shen, B.5    Li, Y.6
  • 29
    • 84863357550 scopus 로고    scopus 로고
    • MiR-181a post-transcriptionally downregulates oncogenic RalA and contributes to growth inhibition and apoptosis in chronic myelogenous leukemia (CML)
    • Fei J, Li Y, Zhu X, Luo X. miR-181a post-transcriptionally downregulates oncogenic RalA and contributes to growth inhibition and apoptosis in chronic myelogenous leukemia (CML). PLoS ONE 2012, 7: e32834
    • (2012) PLoS ONE , vol.7 , pp. e32834
    • Fei, J.1    Li, Y.2    Zhu, X.3    Luo, X.4
  • 30
    • 84879414000 scopus 로고    scopus 로고
    • MiR-181a confers resistance of cervical cancer to radiation therapy through targeting the pro-apoptotic PRKCD gene
    • Ke G, Liang L, Yang JM, Huang X, Han D, Huang S, Zhao Y, et al. MiR-181a confers resistance of cervical cancer to radiation therapy through targeting the pro-apoptotic PRKCD gene. Oncogene 2013, 32: 3019-3027
    • (2013) Oncogene , vol.32 , pp. 3019-3027
    • Ke, G.1    Liang, L.2    Yang, J.M.3    Huang, X.4    Han, D.5    Huang, S.6    Zhao, Y.7
  • 31
    • 79151484006 scopus 로고    scopus 로고
    • MiR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-ras
    • Shin KH, Bae SD, Hong HS, Kim RH, KangMK, Park NH. miR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-ras. Biochem Biophys Res Commun 2011, 404: 896-902
    • (2011) Biochem Biophys Res Commun , vol.404 , pp. 896-902
    • Shin, K.H.1    Bae, S.D.2    Hong, H.S.3    Kim, R.H.4    Kang, M.K.5    Park, N.H.6
  • 32
    • 77949445582 scopus 로고    scopus 로고
    • MicroRNA-181a sensitizes human malignant glioma U87MG cells to radiation by targeting Bcl-2
    • Chen G, ZhuW, Shi D, Lv L, Zhang C, Liu P, HuW. MicroRNA-181a sensitizes human malignant glioma U87MG cells to radiation by targeting Bcl-2. Oncol Rep 2010, 23: 997-1003
    • (2010) Oncol Rep , vol.23 , pp. 997-1003
    • Chen, G.1    Zhu, W.2    Shi, D.3    Lv, L.4    Zhang, C.5    Liu, P.6    Hu, W.7
  • 33
    • 84866179216 scopus 로고    scopus 로고
    • Modulating the strength and threshold of NOTCH oncogenic signals by mir-181a-1/b-1
    • Fragoso R, Mao T, Wang S, Schaffert S, Gong X, Yue S, Luong R, et al. Modulating the strength and threshold of NOTCH oncogenic signals by mir-181a-1/b-1. PLoS Genet 2012, 8: e1002855
    • (2012) PLoS Genet , vol.8 , pp. e1002855
    • Fragoso, R.1    Mao, T.2    Wang, S.3    Schaffert, S.4    Gong, X.5    Yue, S.6    Luong, R.7
  • 34
    • 28844509531 scopus 로고    scopus 로고
    • K-ras as a target for cancer therapy
    • Friday BB, Adjei AA. K-ras as a target for cancer therapy. Biochim Biophys Acta 2005, 1756: 127-144
    • (2005) Biochim Biophys Acta , vol.1756 , pp. 127-144
    • Friday, B.B.1    Adjei, A.A.2
  • 35
    • 3042558512 scopus 로고    scopus 로고
    • Predictive factors for pancreatic cancer in patients with chronic pancreatitis in association with K-ras gene mutation
    • Arvanitakis M, Van Laethem JL, Parma J, De Maertelaer V, Delhaye M, Deviere J. Predictive factors for pancreatic cancer in patients with chronic pancreatitis in association with K-ras gene mutation. Endoscopy 2004, 36: 535-542
    • (2004) Endoscopy , vol.36 , pp. 535-542
    • Arvanitakis, M.1    Van Laethem, J.L.2    Parma, J.3    De Maertelaer, V.4    Delhaye, M.5    Deviere, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.