Piroxicam, a traditional non-steroidal anti-inflammatory drug (NSAID) causes apoptosis by ROS mediated Akt activation

Pharmacological Reports

Volumn 67, Issue 6, 2015, Pages 1215-1223

  Rai, Neha ^a   Sarkar, Munna ^a   Raha, Sanghamitra ^a,b  

^a SAHA INSTITUTE OF NUCLEAR PHYSICS   (India)

^b VISVA BHARATI UNIVERSITY   (India)

Author keywords

Abbreviations NSAID non steroidal anti inflammatory drug; COX cyclooxygenase; NAC N acetyl cysteine; Px piroxicam.; ROS reactive oxygen species; T triciribine

Indexed keywords

PIROXICAM; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TRICIRIBINE; ACETYLCYSTEINE; CASPASE 3; NONSTEROID ANTIINFLAMMATORY AGENT; RIBONUCLEOSIDE;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; ANTAGONISTS AND INHIBITORS; CELL CYCLE; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; PHOSPHORYLATION; TUMOR CELL LINE; UPREGULATION;

ACETYLCYSTEINE; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; CASPASE 3; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; PHOSPHORYLATION; PIROXICAM; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; RIBONUCLEOSIDES; RNA, SMALL INTERFERING; UP-REGULATION;

EID: 84941562540     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/j.pharep.2015.05.012     Document Type: Article

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