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Volumn 9, Issue 1, 2016, Pages 1-11

Characterization of M1/M2 Tumour-Associated Macrophages (TAMs) and Th1/Th2 Cytokine Profiles in Patients with NSCLC

Author keywords

Lung cancer; Lung tissue; M1 macrophages; M2 macrophages; Tumour associated macrophages

Indexed keywords

CD163 ANTIGEN; CD68 ANTIGEN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8;

EID: 84941358498     PISSN: 18752292     EISSN: 18752284     Source Type: Journal    
DOI: 10.1007/s12307-015-0174-x     Document Type: Article
Times cited : (114)

References (52)
  • 1
    • 34249338002 scopus 로고    scopus 로고
    • Tumor-associated macrophage: its role in cancer invasion and metastasis
    • COI: 1:CAS:528:DC%2BD28XnslCnu7c%3D
    • Shih J-Y, Yuan A, Chen JJ-W, Yang P-C (2006) Tumor-associated macrophage: its role in cancer invasion and metastasis. J Cancer Mol 2(3):101–106
    • (2006) J Cancer Mol , vol.2 , Issue.3 , pp. 101-106
    • Shih, J.-Y.1    Yuan, A.2    Chen, J.J.-W.3    Yang, P.-C.4
  • 2
    • 31544441610 scopus 로고    scopus 로고
    • Distinct role of macrophages in different tumor microenvironments
    • COI: 1:CAS:528:DC%2BD28XlsFOmtw%3D%3D, PID: 16423985
    • Lewis CE, Pollard JW (2006) Distinct role of macrophages in different tumor microenvironments. Cancer Res 66(2):605–612. doi:10.1158/0008-5472.CAN-05-4005
    • (2006) Cancer Res , vol.66 , Issue.2 , pp. 605-612
    • Lewis, C.E.1    Pollard, J.W.2
  • 3
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • COI: 1:CAS:528:DC%2BD38XotVKktrc%3D, PID: 12401408
    • Mantovani A, Sozzani S, Locati M, Allavena P, Sica A (2002) Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23(11):549–555
    • (2002) Trends Immunol , vol.23 , Issue.11 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 4
    • 33845466231 scopus 로고    scopus 로고
    • Monocyte/macrophage infiltration in tumors: modulators of angiogenesis
    • COI: 1:CAS:528:DC%2BD28XhtlSisLjN, PID: 16997855, 10.1189/jlb.0905495
    • Dirkx AE, Oude Egbrink MG, Wagstaff J, Griffioen AW (2006) Monocyte/macrophage infiltration in tumors: modulators of angiogenesis. J Leukoc Biol 80(6):1183–1196, 10.1189/jlb.0905495
    • (2006) J Leukoc Biol , vol.80 , Issue.6 , pp. 1183-1196
    • Dirkx, A.E.1    Oude Egbrink, M.G.2    Wagstaff, J.3    Griffioen, A.W.4
  • 5
    • 33751551172 scopus 로고    scopus 로고
    • Dual role of macrophages in tumor growth and angiogenesis
    • COI: 1:CAS:528:DC%2BD28XhtV2hsLzO, PID: 16864600
    • Lamagna C, Aurrand-Lions M, Imhof BA (2006) Dual role of macrophages in tumor growth and angiogenesis. J Leukoc Biol 80(4):705–713. doi:10.1189/jlb.1105656
    • (2006) J Leukoc Biol , vol.80 , Issue.4 , pp. 705-713
    • Lamagna, C.1    Aurrand-Lions, M.2    Imhof, B.A.3
  • 6
    • 84868030361 scopus 로고    scopus 로고
    • Tumor-associated macrophages: function, phenotype, and link to prognosis in human lung cancer
    • PID: 23145206
    • Quatromoni JG, Eruslanov E (2012) Tumor-associated macrophages: function, phenotype, and link to prognosis in human lung cancer. Am J Transl Res 4(4):376–389
    • (2012) Am J Transl Res , vol.4 , Issue.4 , pp. 376-389
    • Quatromoni, J.G.1    Eruslanov, E.2
  • 7
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • COI: 1:CAS:528:DC%2BD2cXptl2ktbs%3D, PID: 15530839
    • Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M (2004) The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 25(12):677–686
    • (2004) Trends Immunol , vol.25 , Issue.12 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3    Allavena, P.4    Vecchi, A.5    Locati, M.6
  • 9
    • 58849166142 scopus 로고    scopus 로고
    • Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival
    • COI: 1:STN:280:DC%2BD1M%2FkslWktQ%3D%3D, PID: 19118225
    • Ohri CM, Shikotra A, Green RH, Waller DA, Bradding P (2009) Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival. Eur Respir J 33(1):118–126. doi:10.1183/09031936.00065708
    • (2009) Eur Respir J , vol.33 , Issue.1 , pp. 118-126
    • Ohri, C.M.1    Shikotra, A.2    Green, R.H.3    Waller, D.A.4    Bradding, P.5
  • 10
    • 77953183233 scopus 로고    scopus 로고
    • Tumor progression stage and anatomical site regulate tumor-associated macrophage and bone marrow-derived monocyte polarization
    • PID: 20431028
    • Redente EF, Dwyer-Nield LD, Merrick DT, Raina K, Agarwal R, Pao W, Rice PL, Shroyer KR, Malkinson AM (2010) Tumor progression stage and anatomical site regulate tumor-associated macrophage and bone marrow-derived monocyte polarization. Am J Pathol 176(6):2972–2985. doi:10.2353/ajpath.2010.090879
    • (2010) Am J Pathol , vol.176 , Issue.6 , pp. 2972-2985
    • Redente, E.F.1    Dwyer-Nield, L.D.2    Merrick, D.T.3    Raina, K.4    Agarwal, R.5    Pao, W.6    Rice, P.L.7    Shroyer, K.R.8    Malkinson, A.M.9
  • 12
    • 0035113742 scopus 로고    scopus 로고
    • Macrophage arginase promotes tumor cell growth and suppresses nitric oxide-mediated tumor cytotoxicity
    • COI: 1:CAS:528:DC%2BD3MXhsFSqsrc%3D, PID: 11221839
    • Chang CI, Liao JC, Kuo L (2001) Macrophage arginase promotes tumor cell growth and suppresses nitric oxide-mediated tumor cytotoxicity. Cancer Res 61(3):1100–1106
    • (2001) Cancer Res , vol.61 , Issue.3 , pp. 1100-1106
    • Chang, C.I.1    Liao, J.C.2    Kuo, L.3
  • 13
    • 42149099408 scopus 로고    scopus 로고
    • Plasticity of macrophage function during tumor progression: regulation by distinct molecular mechanisms
    • COI: 1:CAS:528:DC%2BD1cXhsVShtrY%3D, PID: 18250403
    • Biswas SK, Sica A, Lewis CE (2008) Plasticity of macrophage function during tumor progression: regulation by distinct molecular mechanisms. J Immunol 180(4):2011–2017
    • (2008) J Immunol , vol.180 , Issue.4 , pp. 2011-2017
    • Biswas, S.K.1    Sica, A.2    Lewis, C.E.3
  • 14
    • 0033984320 scopus 로고    scopus 로고
    • Implications of human macrophage metalloelastase and vascular endothelial growth factor gene expression in angiogenesis of hepatocellular carcinoma
    • COI: 1:STN:280:DC%2BD3c7gtVSmuw%3D%3D, PID: 10636104
    • Gorrin-Rivas MJ, Arii S, Mori A, Takeda Y, Mizumoto M, Furutani M, Imamura M (2000) Implications of human macrophage metalloelastase and vascular endothelial growth factor gene expression in angiogenesis of hepatocellular carcinoma. Ann Surg 231(1):67–73
    • (2000) Ann Surg , vol.231 , Issue.1 , pp. 67-73
    • Gorrin-Rivas, M.J.1    Arii, S.2    Mori, A.3    Takeda, Y.4    Mizumoto, M.5    Furutani, M.6    Imamura, M.7
  • 15
    • 84867504992 scopus 로고    scopus 로고
    • The distribution of macrophages with a M1 or M2 phenotype in relation to prognosis and the molecular characteristics of colorectal cancer
    • COI: 1:CAS:528:DC%2BC38Xhs1Sit73E, PID: 23077543
    • Edin S, Wikberg ML, Dahlin AM, Rutegard J, Oberg A, Oldenborg PA, Palmqvist R (2012) The distribution of macrophages with a M1 or M2 phenotype in relation to prognosis and the molecular characteristics of colorectal cancer. PLoS One 7(10), e47045. doi:10.1371/journal.pone.0047045
    • (2012) PLoS One , vol.7 , Issue.10
    • Edin, S.1    Wikberg, M.L.2    Dahlin, A.M.3    Rutegard, J.4    Oberg, A.5    Oldenborg, P.A.6    Palmqvist, R.7
  • 17
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: in vivo veritas
    • COI: 1:CAS:528:DC%2BC38XjsV2ms7g%3D, PID: 22378047
    • Sica A, Mantovani A (2012) Macrophage plasticity and polarization: in vivo veritas. J Clin Invest 122(3):787–795. doi:10.1172/jci59643
    • (2012) J Clin Invest , vol.122 , Issue.3 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 18
    • 77957748702 scopus 로고    scopus 로고
    • Lung cancer staging essentials: the new TNM staging system and potential imaging pitfalls
    • PID: 20833843
    • UyBico SJ, Wu CC, Suh RD, Le NH, Brown K, Krishnam MS (2010) Lung cancer staging essentials: the new TNM staging system and potential imaging pitfalls. Radiographics 30(5):1163–1181. doi:10.1148/rg.305095166
    • (2010) Radiographics , vol.30 , Issue.5 , pp. 1163-1181
    • UyBico, S.J.1    Wu, C.C.2    Suh, R.D.3    Le, N.H.4    Brown, K.5    Krishnam, M.S.6
  • 19
    • 32644466544 scopus 로고    scopus 로고
    • Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung cancer
    • Welsh TJ, Green RH, Richardson D, Waller DA, O’Byrne KJ, Bradding P (2005) Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung cancer. J Clin Oncol Off J Am Soc Clin Oncol 23(35):8959–8967. doi:10.1200/jco.2005.01.4910
    • (2005) J Clin Oncol Off J Am Soc Clin Oncol , vol.23 , Issue.35 , pp. 8959-8967
    • Welsh, T.J.1    Green, R.H.2    Richardson, D.3    Waller, D.A.4    O’Byrne, K.J.5    Bradding, P.6
  • 20
    • 80053640221 scopus 로고    scopus 로고
    • Tumor-associated macrophages provide a suitable microenvironment for non-small lung cancer invasion and progression
    • Wang R, Zhang J, Chen S, Lu M, Luo X, Yao S, Liu S, Qin Y, Chen H (2011) Tumor-associated macrophages provide a suitable microenvironment for non-small lung cancer invasion and progression. Lung Cancer (Amsterdam, Netherlands) 74(2):188–196. doi:10.1016/j.lungcan.2011.04.009
    • (2011) Lung Cancer (Amsterdam, Netherlands) , vol.74 , Issue.2 , pp. 188-196
    • Wang, R.1    Zhang, J.2    Chen, S.3    Lu, M.4    Luo, X.5    Yao, S.6    Liu, S.7    Qin, Y.8    Chen, H.9
  • 21
    • 0032867830 scopus 로고    scopus 로고
    • Tumor-associated macrophage infiltration in pulmonary adenocarcinoma: association with angiogenesis and poor prognosis
    • COI: 1:STN:280:DyaK1MzptFykug%3D%3D, PID: 10461061
    • Takanami I, Takeuchi K, Kodaira S (1999) Tumor-associated macrophage infiltration in pulmonary adenocarcinoma: association with angiogenesis and poor prognosis. Oncology 57(2):138–142
    • (1999) Oncology , vol.57 , Issue.2 , pp. 138-142
    • Takanami, I.1    Takeuchi, K.2    Kodaira, S.3
  • 24
    • 79960690706 scopus 로고    scopus 로고
    • The tissue microlocalisation and cellular expression of CD163, VEGF, HLA-DR, iNOS, and MRP 8/14 is correlated to clinical outcome in NSCLC
    • COI: 1:CAS:528:DC%2BC3MXhtVGqs7%2FK, PID: 21799753
    • Ohri CM, Shikotra A, Green RH, Waller DA, Bradding P (2011) The tissue microlocalisation and cellular expression of CD163, VEGF, HLA-DR, iNOS, and MRP 8/14 is correlated to clinical outcome in NSCLC. PLoS One 6(7), e21874. doi:10.1371/journal.pone.0021874
    • (2011) PLoS One , vol.6 , Issue.7
    • Ohri, C.M.1    Shikotra, A.2    Green, R.H.3    Waller, D.A.4    Bradding, P.5
  • 25
    • 0036187615 scopus 로고    scopus 로고
    • The role of tumour‐associated macrophages in tumour progression: implications for new anticancer therapies
    • COI: 1:STN:280:DC%2BD387it1eksQ%3D%3D, PID: 11857487
    • Bingle L, Brown N, Lewis C (2002) The role of tumour‐associated macrophages in tumour progression: implications for new anticancer therapies. J Pathol 196(3):254–265
    • (2002) J Pathol , vol.196 , Issue.3 , pp. 254-265
    • Bingle, L.1    Brown, N.2    Lewis, C.3
  • 26
    • 0037454777 scopus 로고    scopus 로고
    • Infiltrating immune cells, but not tumour cells, express FasL in non-small cell lung cancer: No association with prognosis identified in 3-year follow-up
    • COI: 1:CAS:528:DC%2BD3sXht1yitA%3D%3D
    • Toomey D, Smyth G, Condron C, Kelly J, Byrne AM, Kay E, Conroy RM, Broe P, Bouchier-Hayes D (2003) Infiltrating immune cells, but not tumour cells, express FasL in non-small cell lung cancer: No association with prognosis identified in 3-year follow-up. Int J Cancer J Int Cancer 103(3):408–412. doi:10.1002/ijc.10836
    • (2003) Int J Cancer J Int Cancer , vol.103 , Issue.3 , pp. 408-412
    • Toomey, D.1    Smyth, G.2    Condron, C.3    Kelly, J.4    Byrne, A.M.5    Kay, E.6    Conroy, R.M.7    Broe, P.8    Bouchier-Hayes, D.9
  • 27
    • 0346671183 scopus 로고    scopus 로고
    • Association of macrophages, mast cells and eosinophil leukocytes with angiogenesis and tumor stage in non-small cell lung carcinomas (NSCLC)
    • Tataroglu C, Kargi A, Ozkal S, Esrefoglu N, Akkoclu A (2004) Association of macrophages, mast cells and eosinophil leukocytes with angiogenesis and tumor stage in non-small cell lung carcinomas (NSCLC). Lung Cancer (Amsterdam, Netherlands) 43(1):47–54
    • (2004) Lung Cancer (Amsterdam, Netherlands) , vol.43 , Issue.1 , pp. 47-54
    • Tataroglu, C.1    Kargi, A.2    Ozkal, S.3    Esrefoglu, N.4    Akkoclu, A.5
  • 28
    • 77952937103 scopus 로고    scopus 로고
    • The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time
    • PID: 20338029
    • Ma J, Liu L, Che G, Yu N, Dai F, You Z (2010) The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time. BMC Cancer 10:112. doi:10.1186/1471-2407-10-112
    • (2010) BMC Cancer , vol.10 , pp. 112
    • Ma, J.1    Liu, L.2    Che, G.3    Yu, N.4    Dai, F.5    You, Z.6
  • 30
    • 0029913684 scopus 로고    scopus 로고
    • The altered tumoricidal capacity of macrophages isolated from tumor-bearing mice is related to reduce expression of the inducible nitric oxide synthase gene
    • COI: 1:CAS:528:DyaK28XisFentbg%3D, PID: 8666890
    • Dinapoli MR, Calderon CL, Lopez DM (1996) The altered tumoricidal capacity of macrophages isolated from tumor-bearing mice is related to reduce expression of the inducible nitric oxide synthase gene. J Exp Med 183(4):1323–1329
    • (1996) J Exp Med , vol.183 , Issue.4 , pp. 1323-1329
    • Dinapoli, M.R.1    Calderon, C.L.2    Lopez, D.M.3
  • 32
    • 81555202006 scopus 로고    scopus 로고
    • M2-polarized tumor-associated macrophages are associated with poor prognoses resulting from accelerated lymphangiogenesis in lung adenocarcinoma
    • PID: 22086517
    • Zhang B, Yao G, Zhang Y, Gao J, Yang B, Rao Z, Gao J (2011) M2-polarized tumor-associated macrophages are associated with poor prognoses resulting from accelerated lymphangiogenesis in lung adenocarcinoma. Clinics 66(11):1879–1886. doi:10.1590/S1807-59322011001100006
    • (2011) Clinics , vol.66 , Issue.11 , pp. 1879-1886
    • Zhang, B.1    Yao, G.2    Zhang, Y.3    Gao, J.4    Yang, B.5    Rao, Z.6    Gao, J.7
  • 34
    • 0036533489 scopus 로고    scopus 로고
    • Cytokines as a link between innate and adaptive antitumor immunity
    • COI: 1:CAS:528:DC%2BD38XitlGhs7k%3D, PID: 11923115
    • Belardelli F, Ferrantini M (2002) Cytokines as a link between innate and adaptive antitumor immunity. Trends Immunol 23(4):201–208
    • (2002) Trends Immunol , vol.23 , Issue.4 , pp. 201-208
    • Belardelli, F.1    Ferrantini, M.2
  • 36
    • 0028978680 scopus 로고
    • Biology of human TH1 and TH2 cells
    • COI: 1:CAS:528:DyaK2MXmsVGru70%3D, PID: 7559914
    • Romagnani S (1995) Biology of human TH1 and TH2 cells. J Clin Immunol 15(3):121–129
    • (1995) J Clin Immunol , vol.15 , Issue.3 , pp. 121-129
    • Romagnani, S.1
  • 37
    • 0029846496 scopus 로고    scopus 로고
    • Th1 and Th2 in human diseases
    • COI: 1:CAS:528:DyaK28XlvFWlsbw%3D, PID: 8811042
    • Romagnani S (1996) Th1 and Th2 in human diseases. Clin Immunol Immunopathol 80(3 Pt 1):225–235
    • (1996) Clin Immunol Immunopathol , vol.80 , Issue.3 , pp. 225-235
    • Romagnani, S.1
  • 38
    • 0029144997 scopus 로고
    • Tumor necrosis factor-alpha (TNF-alpha) in pleural fluids
    • COI: 1:STN:280:DyaK28%2FkvVajtg%3D%3D, PID: 7579322
    • Gursel G, Gokcora N, Elbeg S, Samurkasoglu B, Ekim N (1995) Tumor necrosis factor-alpha (TNF-alpha) in pleural fluids. Tuber Lung Dis 76(4):370–371
    • (1995) Tuber Lung Dis , vol.76 , Issue.4 , pp. 370-371
    • Gursel, G.1    Gokcora, N.2    Elbeg, S.3    Samurkasoglu, B.4    Ekim, N.5
  • 40
    • 73649112422 scopus 로고    scopus 로고
    • Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation
    • COI: 1:CAS:528:DC%2BC3cXkvFKgs7c%3D, PID: 20129250
    • Takahashi H, Ogata H, Nishigaki R, Broide DH, Karin M (2010) Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation. Cancer Cell 17(1):89–97. doi:10.1016/j.ccr.2009.12.008
    • (2010) Cancer Cell , vol.17 , Issue.1 , pp. 89-97
    • Takahashi, H.1    Ogata, H.2    Nishigaki, R.3    Broide, D.H.4    Karin, M.5
  • 41
    • 84862902822 scopus 로고    scopus 로고
    • Blockade of interleukin-6 receptor suppresses the proliferation of H460 lung cancer stem cells
    • COI: 1:CAS:528:DC%2BC38Xptl2ksrs%3D, PID: 22552503
    • Yi H, Cho HJ, Cho SM, Jo K, Park JA, Kim NH, Amidon GL, Kim JS, Shin HC (2012) Blockade of interleukin-6 receptor suppresses the proliferation of H460 lung cancer stem cells. Int J Oncol 41(1):310–316. doi:10.3892/ijo.2012.1447
    • (2012) Int J Oncol , vol.41 , Issue.1 , pp. 310-316
    • Yi, H.1    Cho, H.J.2    Cho, S.M.3    Jo, K.4    Park, J.A.5    Kim, N.H.6    Amidon, G.L.7    Kim, J.S.8    Shin, H.C.9
  • 42
    • 0031969898 scopus 로고    scopus 로고
    • Serum levels of interleukin-6 as a prognostic factor in advanced non-small cell lung cancer
    • PID: 9538169
    • De Vita F, Orditura M, Auriemma A, Infusino S, Roscigno A, Catalano G (1998) Serum levels of interleukin-6 as a prognostic factor in advanced non-small cell lung cancer. Oncol Rep 5(3):649–652
    • (1998) Oncol Rep , vol.5 , Issue.3 , pp. 649-652
    • De Vita, F.1    Orditura, M.2    Auriemma, A.3    Infusino, S.4    Roscigno, A.5    Catalano, G.6
  • 43
    • 77249128341 scopus 로고    scopus 로고
    • Cytokines in bronchoalveolar lavage fluid and serum of lung cancer patients during radiotherapy—association of interleukin-8 and VEGF with survival
    • COI: 1:CAS:528:DC%2BC3cXis1Shu74%3D, PID: 20044268
    • Crohns M, Saarelainen S, Laine S, Poussa T, Alho H, Kellokumpu-Lehtinen P (2010) Cytokines in bronchoalveolar lavage fluid and serum of lung cancer patients during radiotherapy—association of interleukin-8 and VEGF with survival. Cytokine 50(1):30–36. doi:10.1016/j.cyto.2009.11.017
    • (2010) Cytokine , vol.50 , Issue.1 , pp. 30-36
    • Crohns, M.1    Saarelainen, S.2    Laine, S.3    Poussa, T.4    Alho, H.5    Kellokumpu-Lehtinen, P.6
  • 44
    • 77952490197 scopus 로고    scopus 로고
    • Differential expression of toll-like receptors on human alveolar macrophages and autologous peripheral monocytes
    • PID: 20051129
    • Juarez E, Nunez C, Sada E, Ellner JJ, Schwander SK, Torres M (2010) Differential expression of toll-like receptors on human alveolar macrophages and autologous peripheral monocytes. Respir Res 11:2
    • (2010) Respir Res , vol.11 , pp. 2
    • Juarez, E.1    Nunez, C.2    Sada, E.3    Ellner, J.J.4    Schwander, S.K.5    Torres, M.6
  • 45
    • 58149232586 scopus 로고    scopus 로고
    • The interleukin-8 pathway in cancer
    • COI: 1:CAS:528:DC%2BD1cXhtlens7vL, PID: 18980965
    • Waugh DJ, Wilson C (2008) The interleukin-8 pathway in cancer. Clin Cancer Res 14(21):6735–6741. doi:10.1158/1078-0432.CCR-07-4843
    • (2008) Clin Cancer Res , vol.14 , Issue.21 , pp. 6735-6741
    • Waugh, D.J.1    Wilson, C.2
  • 46
    • 33845546703 scopus 로고    scopus 로고
    • The involvement of IL-1 in tumorigenesis, tumor invasiveness, metastasis and tumor-host interactions
    • COI: 1:CAS:528:DC%2BD28Xht1yktb3E, PID: 17043764
    • Apte RN, Dotan S, Elkabets M, White MR, Reich E, Carmi Y, Song X, Dvozkin T, Krelin Y, Voronov E (2006) The involvement of IL-1 in tumorigenesis, tumor invasiveness, metastasis and tumor-host interactions. Cancer Metastasis Rev 25(3):387–408. doi:10.1007/s10555-006-9004-4
    • (2006) Cancer Metastasis Rev , vol.25 , Issue.3 , pp. 387-408
    • Apte, R.N.1    Dotan, S.2    Elkabets, M.3    White, M.R.4    Reich, E.5    Carmi, Y.6    Song, X.7    Dvozkin, T.8    Krelin, Y.9    Voronov, E.10
  • 47
    • 0037314662 scopus 로고    scopus 로고
    • Up-regulation of tumor interleukin-8 expression by infiltrating macrophages: its correlation with tumor angiogenesis and patient survival in non-small cell lung cancer
    • COI: 1:CAS:528:DC%2BD3sXhtVKksLs%3D, PID: 12576442
    • Chen JJ, Yao PL, Yuan A, Hong TM, Shun CT, Kuo ML, Lee YC, Yang PC (2003) Up-regulation of tumor interleukin-8 expression by infiltrating macrophages: its correlation with tumor angiogenesis and patient survival in non-small cell lung cancer. Clin Cancer Res 9(2):729–737
    • (2003) Clin Cancer Res , vol.9 , Issue.2 , pp. 729-737
    • Chen, J.J.1    Yao, P.L.2    Yuan, A.3    Hong, T.M.4    Shun, C.T.5    Kuo, M.L.6    Lee, Y.C.7    Yang, P.C.8
  • 48
    • 54049149463 scopus 로고    scopus 로고
    • Circulating human interleukin-8 as an indicator of cancer progression in a nude rat orthotopic human non-small cell lung carcinoma model
    • COI: 1:CAS:528:DC%2BD1cXpvFKmsbc%3D, PID: 18708412
    • Millar HJ, Nemeth JA, McCabe FL, Pikounis B, Wickstrom E (2008) Circulating human interleukin-8 as an indicator of cancer progression in a nude rat orthotopic human non-small cell lung carcinoma model. Cancer Epidemiol Biomarkers Prev 17(8):2180–2187. doi:10.1158/1055-9965.EPI-07-2915
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , Issue.8 , pp. 2180-2187
    • Millar, H.J.1    Nemeth, J.A.2    McCabe, F.L.3    Pikounis, B.4    Wickstrom, E.5
  • 49
    • 78650934214 scopus 로고    scopus 로고
    • Cytokine disbalance in common human cancers
    • COI: 1:CAS:528:DC%2BC3MXpsVemsg%3D%3D, PID: 21167870
    • Culig Z (2011) Cytokine disbalance in common human cancers. Biochim Biophys Acta 1813(2):308–314. doi:10.1016/j.bbamcr.2010.12.010
    • (2011) Biochim Biophys Acta , vol.1813 , Issue.2 , pp. 308-314
    • Culig, Z.1
  • 51
    • 84855580949 scopus 로고    scopus 로고
    • Gender-specific cytokine pathways, targets, and biomarkers for the switch from health to adenoma and colorectal cancer
    • 819724
    • Pellegrini P, Contasta I, Del Beato T, Ciccone F, Berghella AM (2011) Gender-specific cytokine pathways, targets, and biomarkers for the switch from health to adenoma and colorectal cancer. Clin Dev Immunol 819724. doi:10.1155/2011/819724
    • (2011) Clin Dev Immunol
    • Pellegrini, P.1    Contasta, I.2    Del Beato, T.3    Ciccone, F.4    Berghella, A.M.5
  • 52
    • 0025034650 scopus 로고
    • Effects of gender and sex steroids on the immune response
    • COI: 1:CAS:528:DyaK3cXhslKnu7w%3D, PID: 2407902
    • Schuurs AH, Verheul HA (1990) Effects of gender and sex steroids on the immune response. J Steroid Biochem 35(2):157–172
    • (1990) J Steroid Biochem , vol.35 , Issue.2 , pp. 157-172
    • Schuurs, A.H.1    Verheul, H.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.