메뉴 건너뛰기




Volumn 66, Issue 11, 2011, Pages 1879-1886

M2-Polarized tumor-associated macrophages are associated with poor prognoses resulting from accelerated lymphangiogenesis in lung adenocarcinoma

Author keywords

Lung adenocarcinoma; Lymphangiogenesis; M2 polarized macrophages; Prognosis; Tumor associated macrophages

Indexed keywords


EID: 81555202006     PISSN: 18075932     EISSN: None     Source Type: Journal    
DOI: 10.1590/S1807-59322011001100006     Document Type: Article
Times cited : (154)

References (39)
  • 2
    • 76549119724 scopus 로고    scopus 로고
    • La mala educación of tumor-associated macrophages: Diverse pathways and new players
    • doi: 10.1016/j.ccr.2010.01.019
    • Mantovani A. La mala educación of tumor-associated macrophages: diverse pathways and new players. Cancer Cell. 2010;17:111-2, doi: 10.1016/j.ccr.2010.01.019.
    • (2010) Cancer Cell , vol.17 , pp. 111-112
    • Mantovani, A.1
  • 3
    • 56649101166 scopus 로고    scopus 로고
    • Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer
    • doi:10.1677/ERC-08-0036
    • Ryder M, Ghossein RA, Ricarte-Filho JC, Knauf JA, Fagin JA. Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer. Endocr Relat Cancer. 2008;15:1069-74, doi:10.1677/ERC-08-0036.
    • (2008) Endocr Relat Cancer , vol.15 , pp. 1069-1074
    • Ryder, M.1    Ghossein, R.A.2    Ricarte-Filho, J.C.3    Knauf, J.A.4    Fagin, J.A.5
  • 4
    • 40949114019 scopus 로고    scopus 로고
    • Prognostic significance of macrophage infiltration in leiomyosarcomas
    • doi:10.1158/1078-0432.CCR-07-1712
    • Lee CH, Espinosa I, Vrijaldenhoven S, Subramanian S, Montgomery KD, Zhu S, et al. Prognostic significance of macrophage infiltration in leiomyosarcomas. Clin Cancer Res. 2008;14:1423-30, doi:10.1158/1078-0432.CCR-07-1712.
    • (2008) Clin Cancer Res , vol.14 , pp. 1423-1430
    • Lee, C.H.1    Espinosa, I.2    Vrijaldenhoven, S.3    Subramanian, S.4    Montgomery, K.D.5    Zhu, S.6
  • 5
    • 60449116032 scopus 로고    scopus 로고
    • Tumorassociated macrophage correlated with angiogenesis and progression of mucoepidermoid carcinoma of salivary glands
    • doi:10.1245/s10434-008-0259-6
    • Shieh YS, Hung YJ, Hsieh CB, Chen JS, Chou KC, Liu SY. Tumorassociated macrophage correlated with angiogenesis and progression of mucoepidermoid carcinoma of salivary glands. Ann Surg Oncol. 2009;16:751-60, doi:10.1245/s10434-008-0259-6.
    • (2009) Ann Surg Oncol , vol.16 , pp. 751-760
    • Shieh, Y.S.1    Hung, Y.J.2    Hsieh, C.B.3    Chen, J.S.4    Chou, K.C.5    Liu, S.Y.6
  • 6
    • 31544441610 scopus 로고    scopus 로고
    • Distinct role of macrophages in different tumor microenvironments
    • doi: 10.1158/0008-5472.CAN-05-4005
    • Lewis CE, Pollard JW. Distinct role of macrophages in different tumor microenvironments. Cancer Res. 2006;66:605-12, doi: 10.1158/0008-5472.CAN-05-4005.
    • (2006) Cancer Res , vol.66 , pp. 605-612
    • Lewis, C.E.1    Pollard, J.W.2
  • 7
    • 0037310024 scopus 로고    scopus 로고
    • The many faces of macrophage activation
    • doi: 10.1189/jlb.0602325
    • Mosser DM. The many faces of macrophage activation. J Leukoc Biol. 2003;73:209-12, doi: 10.1189/jlb.0602325
    • (2003) J Leukoc Biol , vol.73 , pp. 209-212
    • Mosser, D.M.1
  • 8
    • 33845398215 scopus 로고    scopus 로고
    • Biochemical and functional characterization of three activated macrophage populations
    • doi: 10.1189/jlb.0406249
    • Edwards JP, Zhang X, Frauwirth KA, Mosser DM. Biochemical and functional characterization of three activated macrophage populations. J Leukoc Biol. 2006;80:1298-307, doi: 10.1189/jlb.0406249.
    • (2006) J Leukoc Biol , vol.80 , pp. 1298-1307
    • Edwards, J.P.1    Zhang, X.2    Frauwirth, K.A.3    Mosser, D.M.4
  • 9
    • 0026762988 scopus 로고
    • Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation
    • doi: 10.1084/jem.176.1.287
    • Stein M, Keshav S, Harris N, Gordon S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J Exp Med. 1992;176:287-92, doi: 10.1084/jem.176.1.287.
    • (1992) J Exp Med , vol.176 , pp. 287-292
    • Stein, M.1    Keshav, S.2    Harris, N.3    Gordon, S.4
  • 10
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • doi: 10.1038/nri978
    • Gordon S. Alternative activation of macrophages. Nat Rev Immunol. 2003;3:23-35, doi: 10.1038/nri978.
    • (2003) Nat Rev Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 11
    • 33747333126 scopus 로고    scopus 로고
    • Mphi1 and Mphi2 can be re-polarized by Th2 or Th1 cytokines, respectively, and respond to exogenous danger signals
    • doi: 10.1016/j.imbio.2006.05.017
    • Gratchev A, Kzhyshkowska J, Köthe K, Muller-Molinet I, Kannookadan S, Utikal J, et al. Mphi1 and Mphi2 can be re-polarized by Th2 or Th1 cytokines, respectively, and respond to exogenous danger signals. Immunobiology. 2006;211:473-86, doi: 10.1016/j.imbio.2006.05.017.
    • (2006) Immunobiology , vol.211 , pp. 473-486
    • Gratchev, A.1    Kzhyshkowska, J.2    Köthe, K.3    Muller-Molinet, I.4    Kannookadan, S.5    Utikal, J.6
  • 12
    • 3142644996 scopus 로고    scopus 로고
    • Tumour-associated macrophages as a prototypic type II polarised phagocyte population: Role in tumour progression
    • doi: 10.1016/j.ejca.2004.03.016
    • Mantovani A, Allavena P, Sica A. Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression. Eur J Cancer. 2004;40:1660-7, doi: 10.1016/j.ejca.2004.03.016.
    • (2004) Eur J Cancer , vol.40 , pp. 1660-1667
    • Mantovani, A.1    Allavena, P.2    Sica, A.3
  • 13
    • 33645991795 scopus 로고    scopus 로고
    • Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
    • doi: 10.1016/j.ejca.2006.01.003
    • Sica A, Schioppa T, Mantovani A, Allavena P. Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. Eur J Cancer. 2006;42:717-27, doi: 10.1016/j.ejca.2006.01.003.
    • (2006) Eur J Cancer , vol.42 , pp. 717-727
    • Sica, A.1    Schioppa, T.2    Mantovani, A.3    Allavena, P.4
  • 14
    • 38449102676 scopus 로고    scopus 로고
    • Macrophage activation and polarization
    • doi: 10.2741/2692
    • Martinez FO, Sica A, Mantovani A, Locati M. Macrophage activation and polarization. Front Biosci. 2008;13:453-61, doi: 10.2741/2692.
    • (2008) Front Biosci , vol.13 , pp. 453-461
    • Martinez, F.O.1    Sica, A.2    Mantovani, A.3    Locati, M.4
  • 15
    • 33645760428 scopus 로고    scopus 로고
    • Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype
    • Hagemann T, Wilson J, Burke F, Kulbe H, Li NF, Plüddemann A, et al. Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype. J Immunol. 2006;176:5023-32.
    • (2006) J Immunol , vol.176 , pp. 5023-5032
    • Hagemann, T.1    Wilson, J.2    Burke, F.3    Kulbe, H.4    Li, N.F.5    Plüddemann, A.6
  • 16
    • 65349163532 scopus 로고    scopus 로고
    • Detection of M2 macrophages and colony-stimulating factor 1 expression in serous and mucinous ovarian epithelial tumors
    • doi: 10.1111/j.1440-1827.2009.02369.x
    • Kawamura K, Komohara Y, Takaishi K, Katabuchi H, Takeya M. Detection of M2 macrophages and colony-stimulating factor 1 expression in serous and mucinous ovarian epithelial tumors. Pathol Int. 2009;59:300-5, doi: 10.1111/j.1440-1827.2009.02369.x.
    • (2009) Pathol Int , vol.59 , pp. 300-305
    • Kawamura, K.1    Komohara, Y.2    Takaishi, K.3    Katabuchi, H.4    Takeya, M.5
  • 17
    • 50249144131 scopus 로고    scopus 로고
    • Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas
    • doi: 10.1002/path.2370
    • Komohara Y, Ohnishi K, Kuratsu J, Takeya M. Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas. J Pathol. 2008;216:15-24, doi: 10.1002/path.2370.
    • (2008) J Pathol , vol.216 , pp. 15-24
    • Komohara, Y.1    Ohnishi, K.2    Kuratsu, J.3    Takeya, M.4
  • 18
    • 77949695294 scopus 로고    scopus 로고
    • Ratio of M2 macrophage expression is closely associated with poor prognosis for Angioimmunoblastic T-cell lymphoma (AITL)
    • doi: 10.1111/j.1440-1827.2010.02514.x
    • Niino D, Komohara Y, Murayama T, Aoki R, Kimura Y, Hashikawa K, et al. Ratio of M2 macrophage expression is closely associated with poor prognosis for Angioimmunoblastic T-cell lymphoma (AITL). Pathol Int. 2010;60:278-83, doi: 10.1111/j.1440-1827.2010.02514.x.
    • (2010) Pathol Int , vol.60 , pp. 278-283
    • Niino, D.1    Komohara, Y.2    Murayama, T.3    Aoki, R.4    Kimura, Y.5    Hashikawa, K.6
  • 19
    • 30744477450 scopus 로고    scopus 로고
    • Lymphangiogenesis in development and human disease
    • doi: 10.1038/nature 04480
    • Alitalo K, Tammela T, Petrova TV. Lymphangiogenesis in development and human disease. Nature. 2005;438:946-53, doi: 10.1038/nature 04480.
    • (2005) Nature , vol.438 , pp. 946-953
    • Alitalo, K.1    Tammela, T.2    Petrova, T.V.3
  • 20
    • 0035915771 scopus 로고    scopus 로고
    • Lymphatic microvessel density as a novel prognostic factor in early-stage invasive cervical cancer
    • doi: 10.1002/1097-0215(20010120)95:1, 29::AID-IJC1005.3.0.CO;2-W
    • Birner P, Schindl M, Obermair A, Breitenecker G, Kowalski H, Oberhuber G. Lymphatic microvessel density as a novel prognostic factor in early-stage invasive cervical cancer. Int J Cancer. 2001;95:29-33, doi: 10.1002/1097-0215(20010120)95:1,29::AID-IJC1005.3.0.CO;2-W.
    • (2001) Int J Cancer , vol.95 , pp. 29-33
    • Birner, P.1    Schindl, M.2    Obermair, A.3    Breitenecker, G.4    Kowalski, H.5    Oberhuber, G.6
  • 21
    • 61649127531 scopus 로고    scopus 로고
    • Lymphatic vessel densities of lymph node-negative prostate adenocarcinoma in Korea
    • doi: 10.1016/j.prp.2008.10.005
    • Kim HS, Sung W, Lee S, Chang SG, Park YK. Lymphatic vessel densities of lymph node-negative prostate adenocarcinoma in Korea. Pathol Res Pract. 2009;205:249-54, doi: 10.1016/j.prp.2008.10.005.
    • (2009) Pathol Res Pract , vol.205 , pp. 249-254
    • Kim, H.S.1    Sung, W.2    Lee, S.3    Chang, S.G.4    Park, Y.K.5
  • 22
    • 27144543581 scopus 로고    scopus 로고
    • Lymphangiogenesis correlates with lymph node metastasis, prognosis, and angiogenic phenotype in human non-small cell lung cancer
    • doi: 10.1158/1078-0432.CCR-05-1077
    • Renyi-Vamos F, Tovari J, Fillinger J, Timar J, Paku S, Kenessey I, et al. Lymphangiogenesis correlates with lymph node metastasis, prognosis, and angiogenic phenotype in human non-small cell lung cancer. Clin Cancer Res. 2005;11:7344-53, doi: 10.1158/1078-0432.CCR-05-1077.
    • (2005) Clin Cancer Res , vol.11 , pp. 7344-7353
    • Renyi-Vamos, F.1    Tovari, J.2    Fillinger, J.3    Timar, J.4    Paku, S.5    Kenessey, I.6
  • 23
    • 42649083375 scopus 로고    scopus 로고
    • The clinical significance of lymphangiogenesis and angiogenesis in non-small cell lung cancer patients
    • doi: 10.1016/j.ejca.2008.03.012
    • Kadota K, Huang CL, Liu D, Ueno M, Kushida Y, Haba R, et al. The clinical significance of lymphangiogenesis and angiogenesis in non-small cell lung cancer patients. Eur J Cancer. 2008;44:1057-67, doi: 10.1016/j.ejca.2008.03.012.
    • (2008) Eur J Cancer , vol.44 , pp. 1057-1067
    • Kadota, K.1    Huang, C.L.2    Liu, D.3    Ueno, M.4    Kushida, Y.5    Haba, R.6
  • 24
    • 0036733564 scopus 로고    scopus 로고
    • Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis
    • doi: 10.1016/S0002-9440(10)64255-1
    • Schoppmann SF, Birner P, Stöckl J, Kalt R, Ullrich R, Caucig C, et al. Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis. Am J Pathol. 2002;161:947-56, doi: 10.1016/S0002-9440(10)64255-1.
    • (2002) Am J Pathol , vol.161 , pp. 947-956
    • Schoppmann, S.F.1    Birner, P.2    Stöckl, J.3    Kalt, R.4    Ullrich, R.5    Caucig, C.6
  • 25
    • 33745165865 scopus 로고    scopus 로고
    • VEGF-C expressing tumor-associated macrophages in lymph node positive breast cancer: Impact on lymphangiogenesis and survival
    • doi: 10.1016/j.surg.2005.12.008
    • Schoppmann SF, Fenzl A, Nagy K, Unger S, Bayer G, Geleff S, et al. VEGF-C expressing tumor-associated macrophages in lymph node positive breast cancer: impact on lymphangiogenesis and survival. Surgery. 2006;139:839-46, doi: 10.1016/j.surg.2005.12.008.
    • (2006) Surgery , vol.139 , pp. 839-846
    • Schoppmann, S.F.1    Fenzl, A.2    Nagy, K.3    Unger, S.4    Bayer, G.5    Geleff, S.6
  • 26
    • 0036715251 scopus 로고    scopus 로고
    • A new monoclonal antibody, D2-40, for detection of lymphatic invasion in primary tumors
    • Kahn HJ, Marks A. A new monoclonal antibody, D2-40, for detection of lymphatic invasion in primary tumors. Lab Invest. 2002;82:1255-7.
    • (2002) Lab Invest , vol.82 , pp. 1255-1257
    • Kahn, H.J.1    Marks, A.2
  • 27
    • 79954500386 scopus 로고    scopus 로고
    • Multiplexed analysis of angiogenesis and lymphangiogenesis factors predicts outcome for non-small cell lung cancer patients
    • doi: 10.1007/s00428-010-1015-4
    • Anagnostou VK, Tiniakos DG, Fotinou M, Achimastos A, Syrigos KN. Multiplexed analysis of angiogenesis and lymphangiogenesis factors predicts outcome for non-small cell lung cancer patients. Virchows Arch. 2011;458:331-40, doi: 10.1007/s00428-010-1015-4.
    • (2011) Virchows Arch , vol.458 , pp. 331-340
    • Anagnostou, V.K.1    Tiniakos, D.G.2    Fotinou, M.3    Achimastos, A.4    Syrigos, K.N.5
  • 28
    • 0041917266 scopus 로고    scopus 로고
    • Th1/Th2 balance: The hypothesis, its limitations, and implications for health and disease
    • Kidd P. Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease. Altern Med Rev. 2003;8:223-246.
    • (2003) Altern Med Rev , vol.8 , pp. 223-246
    • Kidd, P.1
  • 29
    • 0029124129 scopus 로고
    • Human non-small cell lung cancer cells express a type 2 cytokine pattern
    • Huang M, Wang J, Lee P, Sharma S, Mao JT, Meissner H, et al. Human non-small cell lung cancer cells express a type 2 cytokine pattern. Cancer Res. 1995;55:3847-53.
    • (1995) Cancer Res , vol.55 , pp. 3847-3853
    • Huang, M.1    Wang, J.2    Lee, P.3    Sharma, S.4    Mao, J.T.5    Meissner, H.6
  • 30
    • 0033152737 scopus 로고    scopus 로고
    • Lung carcinoma: Analysis of T helper type 1 and 2 cells and T cytotoxic type 1 and 2 cells by intracellular cytokine detection with flow cytometry
    • doi: 10.1002/(SICI)1097-0142(19990601)85:11,2359::AID-CNCR10.3.0.CO;2-A
    • Ito N, Nakamura H, Tanaka Y, Ohgi S. Lung carcinoma: analysis of T helper type 1 and 2 cells and T cytotoxic type 1 and 2 cells by intracellular cytokine detection with flow cytometry. Cancer. 1999;85:2359-67, doi: 10.1002/(SICI)1097-0142(19990601)85:11,2359::AID-CNCR10.3.0.CO;2-A.
    • (1999) Cancer , vol.85 , pp. 2359-2367
    • Ito, N.1    Nakamura, H.2    Tanaka, Y.3    Ohgi, S.4
  • 31
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • doi: 10.1016/j.it.2004.09.015
    • Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 2004;25:677-86, doi: 10.1016/j.it.2004.09.015.
    • (2004) Trends Immunol , vol.25 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3    Allavena, P.4    Vecchi, A.5    Locati, M.6
  • 32
    • 77958187950 scopus 로고    scopus 로고
    • Stromal macrophage expressing CD204 is associated with tumor aggressiveness in lung adenocarcinoma
    • doi: 10.1097/JTO.0b013e3181eba692
    • Ohtaki Y, Ishii G, Nagai K, Ashimine S, Kuwata T, Hishida T, et al. Stromal macrophage expressing CD204 is associated with tumor aggressiveness in lung adenocarcinoma. J Thorac Oncol. 2010;5:1507-15, doi: 10.1097/JTO.0b013e3181eba692.
    • (2010) J Thorac Oncol , vol.5 , pp. 1507-1515
    • Ohtaki, Y.1    Ishii, G.2    Nagai, K.3    Ashimine, S.4    Kuwata, T.5    Hishida, T.6
  • 33
    • 46949094641 scopus 로고    scopus 로고
    • Tumorinfiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics
    • doi: 10.1189/jlb.0907611
    • Umemura N, Saio M, Suwa T, Kitoh Y, Bai J, Nonaka K, et al. Tumorinfiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics. J Leukoc Biol. 2008;83:1136-44, doi: 10.1189/jlb.0907611.
    • (2008) J Leukoc Biol , vol.83 , pp. 1136-1144
    • Umemura, N.1    Saio, M.2    Suwa, T.3    Kitoh, Y.4    Bai, J.5    Nonaka, K.6
  • 34
    • 77954855351 scopus 로고    scopus 로고
    • Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma
    • doi: 10. 1111/j.1349-7006.2010.01614.x
    • Hasita H, Komohara Y, Okabe H, Ashimine S, Kuwata T, Hishida T, et al. Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma. Cancer Sci. 2010;101:1913-9, doi: 10. 1111/j.1349-7006.2010.01614.x.
    • (2010) Cancer Sci , vol.101 , pp. 1913-1919
    • Hasita, H.1    Komohara, Y.2    Okabe, H.3    Ashimine, S.4    Kuwata, T.5    Hishida, T.6
  • 35
    • 77949695294 scopus 로고    scopus 로고
    • Ratio of M2 macrophage expression is closely associated with poor prognosis for Angioimmunoblastic T-cell lymphoma (AITL)
    • doi: 10.1111/j.1440-1827.2010.02514.x
    • Niino D, Komohara Y, Murayama T, Aoki R, Kimura Y, Hashikawa K, et al. Ratio of M2 macrophage expression is closely associated with poor prognosis for Angioimmunoblastic T-cell lymphoma (AITL). Pathol Int. 2010;60:278-83, doi: 10.1111/j.1440-1827.2010.02514.x.
    • (2010) Pathol Int , vol.60 , pp. 278-283
    • Niino, D.1    Komohara, Y.2    Murayama, T.3    Aoki, R.4    Kimura, Y.5    Hashikawa, K.6
  • 36
    • 58849166142 scopus 로고    scopus 로고
    • Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1phenotype associated with extended survival
    • doi: 10.1183/09031936.00065708
    • Ohri CM, Shikotra A, Green RH, Waller DA, Bradding P. Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1phenotype associated with extended survival. Eur Respir J. 2009;33:118-26, doi: 10.1183/09031936.00065708.
    • (2009) Eur Respir J , vol.33 , pp. 118-126
    • Ohri, C.M.1    Shikotra, A.2    Green, R.H.3    Waller, D.A.4    Bradding, P.5
  • 37
    • 77952937103 scopus 로고    scopus 로고
    • The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time
    • doi: 10.1186/1471-2407-10-112
    • Ma J, Liu L, Che G, Yu N, Dai F, You Z. The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time. BMC Cancer. 2010;10:112, doi: 10.1186/1471-2407-10-112.
    • (2010) BMC Cancer , vol.10 , pp. 112
    • Ma, J.1    Liu, L.2    Che, G.3    Yu, N.4    Dai, F.5    You, Z.6
  • 38
    • 0034899437 scopus 로고    scopus 로고
    • Lymphangiogenesis and tumor metastasis: Myth or reality?
    • Pepper MS. Lymphangiogenesis and tumor metastasis: myth or reality? Clin Cancer Res. 2001;7:462-8.
    • (2001) Clin Cancer Res , vol.7 , pp. 462-468
    • Pepper, M.S.1
  • 39
    • 66149170239 scopus 로고    scopus 로고
    • Alternatively activated RAW264.7 macrophages enhance tumor lymphangiogenesis in mouse lung adenocarcinoma
    • doi: 10.1002/jcb.22110
    • Zhang B, Wang J, Gao J, Guo Y, Chen X, Wang B, et al. Alternatively activated RAW264.7 macrophages enhance tumor lymphangiogenesis in mouse lung adenocarcinoma. J Cell Biochem. 2009;107:134-43, doi: 10.1002/jcb.22110.
    • (2009) J Cell Biochem , vol.107 , pp. 134-143
    • Zhang, B.1    Wang, J.2    Gao, J.3    Guo, Y.4    Chen, X.5    Wang, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.