Biological age as a method for systematic assessment of ontogenetic changes in the state of an organism

Russian Journal of Developmental Biology

Volumn 46, Issue 5, 2015, Pages 246-253

  Dontsov, V I ^a   Krut'ko V N ^a  

^a INSTITUTE FOR SYSTEMS ANALYSIS   (Russian Federation)

Author keywords

age related changes; aging; biological age

Indexed keywords

EID: 84941340898     PISSN: 10623604     EISSN: 16083326     Source Type: Journal    
DOI: 10.1134/S1062360415050033     Document Type: Review

References (41)

1. Artyukhov, I.P., Medvedeva, N.N., Nikolaev, V.G., et al., On the methodology for assessing the health of the population, Kazan. Med. Zh., 2013, vol. XSIV, no. 4, pp. 522–526.
2. Astakhov, A.V., Determination of biological age of the heart by the functional test, Teor. Prakt. Fiz. Kul’tury, 2013, no. 6, pp. 70–71.
3. Cheremushnikova, I.I., Davydova, N.O., Grivko, N.V., et al., Monitoring the biological age of students as an indicator of adaptation to high school, Vrach-Aspirant, 2012, vol. 53, no. 4, pp. 285–292.
4. Chizhov, A.Ya., Zenchuk, E.S., Krut’ko, V.N., et al., The use of the immune system corrector Transfer Factor to reduce the biological age of humans, Tekhnol. Zhivykh Sist., 2013, vol. 10, no. 1, pp. 41–46.
5. Demin, A.V., Krivetskii, V.V., and Fesenko, V.V., Characteristics of the life quality of men of older age groups with different rates of aging, Fundam. Issled., 2012, no. 72, pp. 296–299.
6. Dontsov, V.I., Krut’ko, V.N., and Trukhanov, A.I., Meditsina anti-stareniya: fundamental’nye osnovy (Anti-Aging Medicine: Fundamentals), Moscow: URSS, 2010.
7. Dontsov, V.I., Novaya immunnaya teoriya stareniya: limfotsity kak regulyatory kletochnogo rosta (A New Immune Theory of Aging: Lymphocytes as Cell Growth Regulators), Lambert Academic Publishing, 2011.
8. Dontsov, V.I. and Krut’ko, V.N., Modeling of aging processes: a new immunoregulatory theory of aging, Usp. Sovrem. Biol., 2010, vol. 130, no. 1, pp. 3–19.
9. Dontsov, V.I., Krut’ko, V.N., and Gavrilov, M.A., A systematic approach to quantitative diagnosis of human aging using the “Diagnosis of Aging” computer system, Informat. Sist. Upravl., 2011, no. 1, pp. 62–64.
10. Dubina, T.L. and Razumovich, A.N., Vvedenie v eksperimental’nuyu gerontologiyu (Introduction to Experimental Gerontology), Minsk, 1975.
11. Evstigneeva, M.I., The concept of “biological age” as an indicator of the level of health and the necessity to study it the medical students, Adapt. Fiz. Kul’tura, 2011, vol. 46, no. 2, pp. 28–30.
12. Gary, A., Borkan, A.H., and Norris, G., Assessment of biological age using a profile of physical parameters, J. Gerontol., 1980, vol. 35, pp. 177–184.
13. Gavrilov, I.V. and Meshchaninov, V.N., Influence of multiple organ pathology on the biological age of male and female patients of different chronological age, Usp. Gerontol., 2012, vol. 25, no. 2, pp. 228–231.
14. Gompertz, B., On the nature of the function expressive of the low human mortality and new model of determining life contingencies, Philos. Trans. Roy. Soc. London, 1825, vol. 115, pp. 513–585.
15. Grigor’eva, L.A., Studies of biological age of adult taiga tick Ixodes persulcatus (Ixodinae), Parazitologiya, 2013, vol. 47, no. 3, pp. 228–234.
16. Gruber, J., Schaffer, S., and Halliwell, B., The mitochondrial free radical theory of ageing—where do we stand?, Front. Biosci., 2008, vol. 13, pp. 554–579.
17. Hayflick, L., Biological aging is no longer an unsolved problem, Ann. N. Y. Acad. Sci., 2000, vol. 1100, pp. 1–13.
18. Karasik, D., Demissie, S., Cupples, A., et al., Disentangling the genetic determinants of human aging: biological age as an alternative to the use of survival measures, J. Gerontol. A Biol. Sci. Med. Sci., 2005, vol. 60, pp. 574–587.
19. Khalyavkin, A.V. and Krutko, V.N., Plasticity of aging via external influences, Rejuvenation Res., 2011, vol. 14, no. 1, pp. 24–30.
20. Komfort, A., Biologiya stareniya (Biology of Aging), Moscow: Mir, 1967.
21. Kosarev, V.V., Babanov, S.A., and Vorob’eva, E.V., Determination of the rate of biological aging in vibration disease, Usp. Gerontol., 2011, vol. 24, no. 2, pp. 300–302.
22. Krut’ko, V.N., Smirnova, T.M., Dontsov, V.I., et al., Diagnosing aging: I. Problem of reliability of linear regression models of biological age, Fiziol. Chel., 2001, vol. 27, no. 6, pp. 725–731.
23. Krut’ko, V.N. and Dontsov, V.I., Sistemnye mekhanizmy i modeli stareniya (Systematic Mechanisms and Models of Aging), Moscow: LKI, 2008.
24. Linton, P. and Thoman, M.L., Tcell senescence, Front. Biosci., 2001, vol. 6, pp. 248–661.
25. Masoro, E. and Austad, S., Eds., Handbook of the Biology of Aging, 7th ed., San Diego: Academic Press, 2011.
26. Matveeva, Yu.P., Lotosh, T.A., Yunash, V.D., et al., Influence of the season of birth of male rats on some parameters of biological age, Ross. Fiziol. Zh. im. I. M. Sechenova, 2013, vol. 99, no. 11, pp. 1322–1332.
27. Milewski, L.A., The evolution of aging, Biosci. Horizons, 2010, vol. 3, no. 1, pp. 77–84.
28. Olovnikov, A., Lunasensor, infradian rhythms, telomeres, and the chronomere program of aging, Ann. N. Y. Acad. Sci., 2005, vol. 1057, pp. 112–132.
29. Pozdnyakova, N.M., Proshchaev, K.I., Il’nitskii, A.N., et al., Modern views on the possibility of assessment of biological age in clinical practice, Fundam. Issled., 2011, no. 2, pp. 17–22.
30. Puchkova, E.I. and Alishev, N.V., Indicators of biological age and accelerated aging of the liquidators of consequences of radiation accidents, Usp. Gerontol., 2011, vol. 24, no. 1, pp. 99–104.
31. Rando, T.A. and Chang, H.Y., Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock, Cell, 2012, vol. 148, nos. 1–2, pp. 46–57.
32. Schuster, P., Mathematical modeling of evolution. Solved and open problems, Theory Biosci., 2011, vol. 130, no. 1, pp. 71–89.
33. Shpagina, L.N. and Filimonov, S.N., Evaluation of biological age and the rate of aging as an indicator of the health of the miners of Kuzbass, Fundam. Issled., 2013, no. 73, pp. 666–669.
34. Sohal, R.S. and Orr, W.C., The redox stress hypothesis of aging, Free Radic. Biol. Med., 2012, vol. 52, pp. 539–555.
35. Strick-Marchand, H., Masse, G.X., Weiss, M.C., et al., Lymphocytes support oval cell-dependent liver regeneration, J. Immunol., 2008, vol. 181, no. 4, pp. 2764–2771.
36. Stuart, W.S., MacDonald, S.W, De Carlo, C.A., et al., Linking biological and cognitive aging: toward improving characterizations of developmentaltime, J. Gerontol., 2011, vol. 66B, pp. i59–i70.
37. Tabatabaie, V., Atzmon, G., Rajpathak, S.N., et al., Exceptional longevity is associated with decreased reproduction, Aging (Albany, N. Y.), 2011, vol. 3, no. 12, pp. 1202–1205.
38. Tomas Loba A., Bernardes de Jesus, B., Mato, J.M., et al., A metabolic signature predicts biological age in mice, Aging Cell, 2013, vol. 12, pp. 93–101.
39. Trifunovic, A., Hansson, A., Wredenberg, A., et al., Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production, Proc. Natl. Acad. Sci. USA, 2005, vol. 102, no. 50, pp. 17993–17998.
40. Turova, E.A., Konchugova, T.V., Balaban, E.I., et al., Effect of procaine electrophoresis and mesotherapy on the indicators of biological age, Vopr. Kurortol. Fizioter. Lecheb. Fiz. Kul’t., 2012, vol. 89, no. 4, pp. 19–22.
41. Vlasova, I.A., The nonspecific adaptation reactions and the functional state of elderly persons, Sib. Med. Zh., 2012, vol. 113, no. 6, pp. 46–48.