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Volumn 10, Issue 7, 2015, Pages

Glucagon-like peptide-1 receptor agonist Liraglutide has anabolic bone effects in ovariectomized rats without diabetes

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; COLLAGEN TYPE 1; FAT DROPLET; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; LIRAGLUTIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR RUNX2; ANABOLIC AGENT; GLUCAGON LIKE PEPTIDE 1 RECEPTOR;

EID: 84941312682     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0132744     Document Type: Article
Times cited : (82)

References (42)
  • 1
    • 78650753885 scopus 로고    scopus 로고
    • Incretin-based therapies for type 2 diabetes mellitus: Properties, functions, and clinical implications
    • 21194578
    • Nauck MA. Incretin-based therapies for type 2 diabetes mellitus: properties, functions, and clinical implications. The American journal of medicine. 2011;124 (1 Suppl):S3-18. doi: 10.1016/j.amjmed.2010.11. 002 PMID: 21194578.
    • (2011) The American Journal of Medicine , vol.124 , Issue.1 , pp. S3-S18
    • Nauck, M.A.1
  • 2
    • 84860390325 scopus 로고    scopus 로고
    • Incretin effect: GLP-1, GIP, DPP4
    • 21864749 Epub 2011/09/01 S0168-8227(11)70011-0
    • Kazafeos K. Incretin effect: GLP-1, GIP, DPP4. Diabetes Res Clin Pract. 2011;93 Suppl 1:S32-6. Epub 2011/09/01. doi: S0168-8227 (11) 70011-0 [pii]doi: 10.1016/S0168-8227 (11) 70011-0 PMID: 21864749.
    • (2011) Diabetes Res Clin Pract , vol.93 , pp. S32-S36
    • Kazafeos, K.1
  • 3
    • 0035516188 scopus 로고    scopus 로고
    • Systemic administration of the long-acting GLP-1 derivative NN2211 induces lasting and reversible weight loss in both normal and obese rats
    • 11679431
    • Larsen PJ, Fledelius C, Knudsen LB, Tang-Christensen M. Systemic administration of the long-acting GLP-1 derivative NN2211 induces lasting and reversible weight loss in both normal and obese rats. Diabetes. 2001;50(11):2530-9. PMID: 11679431.
    • (2001) Diabetes , vol.50 , Issue.11 , pp. 2530-2539
    • Larsen, P.J.1    Fledelius, C.2    Knudsen, L.B.3    Tang-Christensen, M.4
  • 4
    • 84555191794 scopus 로고    scopus 로고
    • Novel GLP-1 receptor agonists for diabetes
    • 22111970
    • Garber AJ. Novel GLP-1 receptor agonists for diabetes. Expert opinion on investigational drugs. 2012;21(1):45-57. doi: 10.1517/13543784.2012.638282 PMID: 22111970.
    • (2012) Expert Opinion on Investigational Drugs , vol.21 , Issue.1 , pp. 45-57
    • Garber, A.J.1
  • 5
    • 33644618433 scopus 로고    scopus 로고
    • The biology of incretin hormones
    • 16517403
    • Drucker DJ. The biology of incretin hormones. Cell metabolism. 2006;3(3):153-65. doi: 10.1016/j. cmet.2006.01.004 PMID: 16517403.
    • (2006) Cell Metabolism , vol.3 , Issue.3 , pp. 153-165
    • Drucker, D.J.1
  • 6
    • 70350619609 scopus 로고    scopus 로고
    • Effects of liraglutide in the treatment of obesity: A randomised, double-blind, placebo-controlled study
    • 19853906
    • Astrup A, Rossner S, Van Gaal L, Rissanen A, Niskanen L, Al Hakim M, et al. Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study. Lancet. 2009;374(9701):1606-16. doi: 10.1016/S0140-6736 (09) 61375-1 PMID: 19853906.
    • (2009) Lancet , vol.374 , Issue.9701 , pp. 1606-1616
    • Astrup, A.1    Rossner, S.2    Van Gaal, L.3    Rissanen, A.4    Niskanen, L.5    Al Hakim, M.6
  • 7
    • 84878808238 scopus 로고    scopus 로고
    • Pharmacology, physiology, and mechanisms of incretin hormone action
    • 23684623
    • Campbell JE, Drucker DJ. Pharmacology, physiology, and mechanisms of incretin hormone action. Cell metabolism. 2013;17(6):819-37. doi: 10.1016/j.cmet.2013.04.008 PMID: 23684623.
    • (2013) Cell Metabolism , vol.17 , Issue.6 , pp. 819-837
    • Campbell, J.E.1    Drucker, D.J.2
  • 8
    • 84860204551 scopus 로고    scopus 로고
    • Cardiovascular biology of the incretin system
    • 22323472 PubMed Central, PMCID: PMC3528785
    • Ussher JR, Drucker DJ. Cardiovascular biology of the incretin system. Endocrine reviews. 2012;33(2):187-215. doi: 10.1210/er.2011-1052 PMID: 22323472; PubMed Central PMCID: PMC3528785.
    • (2012) Endocrine Reviews , vol.33 , Issue.2 , pp. 187-215
    • Ussher, J.R.1    Drucker, D.J.2
  • 9
    • 84865849218 scopus 로고    scopus 로고
    • Potential role of glucagon-like peptide-1 (GLP-1) in neuroprotection
    • 22938097
    • Holscher C. Potential role of glucagon-like peptide-1 (GLP-1) in neuroprotection. CNS drugs. 2012;26(10):871-82. doi: 10.2165/11635890-000000000-00000 PMID: 22938097.
    • (2012) CNS Drugs , vol.26 , Issue.10 , pp. 871-882
    • Holscher, C.1
  • 10
    • 84908627961 scopus 로고    scopus 로고
    • Exendin-4, aGLP-1 receptor agonist, attenuates prostate cancer growth
    • 24879833
    • Nomiyama T, Kawanami T, Irie S, Hamaguchi Y, Terawaki Y, Murase K, et al. Exendin-4, aGLP-1 receptor agonist, attenuates prostate cancer growth. Diabetes. 2014;63(11):3891-905. doi: 10.2337/db13-1169 PMID: 24879833.
    • (2014) Diabetes , vol.63 , Issue.11 , pp. 3891-3905
    • Nomiyama, T.1    Kawanami, T.2    Irie, S.3    Hamaguchi, Y.4    Terawaki, Y.5    Murase, K.6
  • 11
    • 77956496046 scopus 로고    scopus 로고
    • Presence of a functional receptor for GLP-1 in osteoblastic cells, independent of the cAMP-linked GLP-1 receptor
    • 20506394 Epub 2010/05/28
    • Nuche-Berenguer B, Portal-Nunez S, Moreno P, Gonzalez N, Acitores A, Lopez-Herradon A, et al. Presence of a functional receptor for GLP-1 in osteoblastic cells, independent of the cAMP-linked GLP-1 receptor. Journal of cellular physiology. 2010;225(2):585-92. Epub 2010/05/28. doi: 10.1002/jcp. 22243 PMID: 20506394.
    • (2010) Journal of Cellular Physiology , vol.225 , Issue.2 , pp. 585-592
    • Nuche-Berenguer, B.1    Portal-Nunez, S.2    Moreno, P.3    Gonzalez, N.4    Acitores, A.5    Lopez-Herradon, A.6
  • 12
    • 67349094596 scopus 로고    scopus 로고
    • Effect of GLP-1 treatment on bone turnover in normal, type 2 diabetic, and insulin-resistant states
    • 19219381 Epub 2009/02/17
    • Nuche-Berenguer B, Moreno P, Esbrit P, Dapia S, Caeiro JR, Cancelas J, et al. Effect of GLP-1 treatment on bone turnover in normal, type 2 diabetic, and insulin-resistant states. Calcified tissue international. 2009;84(6):453-61. Epub 2009/02/17. doi: 10.1007/s00223-009-9220-3 PMID: 19219381.
    • (2009) Calcified Tissue International , vol.84 , Issue.6 , pp. 453-461
    • Nuche-Berenguer, B.1    Moreno, P.2    Esbrit, P.3    Dapia, S.4    Caeiro, J.R.5    Cancelas, J.6
  • 13
    • 71449084965 scopus 로고    scopus 로고
    • Exendin-4 exerts osteogenic actions in insulin-resistant and type 2 diabetic states
    • 19586609 Epub 2009/07/10 S0167-0115(09)00148-7
    • Nuche-Berenguer B, Moreno P, Portal-Nunez S, Dapia S, Esbrit P, Villanueva-Penacarrillo ML. Exendin-4 exerts osteogenic actions in insulin-resistant and type 2 diabetic states. Regul Pept. 2010;159(1-3):61-6. Epub 2009/07/10. doi: S0167-0115 (09) 00148-7 [pii] doi: 10.1016/j.regpep. 2009.06.010 PMID: 19586609.
    • (2010) Regul Pept , vol.159 , Issue.1-3 , pp. 61-66
    • Nuche-Berenguer, B.1    Moreno, P.2    Portal-Nunez, S.3    Dapia, S.4    Esbrit, P.5    Villanueva-Penacarrillo, M.L.6
  • 15
    • 84879221597 scopus 로고    scopus 로고
    • Exendin-4, a glucagon-like peptide-1 receptor agonist, prevents osteopenia by promoting bone formation and suppressing bone resorption in aged ovariectomized rats
    • 23427056 Epub 2013/02/22
    • Ma X, Meng J, Jia M, Bi L, Zhou Y, Wang Y, et al. Exendin-4, a glucagon-like peptide-1 receptor agonist, prevents osteopenia by promoting bone formation and suppressing bone resorption in aged ovariectomized rats. Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research. 2013;28(7):1641-52. Epub 2013/02/22. doi: 10.1002/jbmr.1898 PMID: 23427056.
    • (2013) Journal of Bone and Mineral Research: The Official Journal of the American Society for Bone and Mineral Research , vol.28 , Issue.7 , pp. 1641-1652
    • Ma, X.1    Meng, J.2    Jia, M.3    Bi, L.4    Zhou, Y.5    Wang, Y.6
  • 16
    • 77349116804 scopus 로고    scopus 로고
    • Signaling and biological effects of glucagon-like peptide 1 on the differentiation of mesenchymal stem cells from human bone marrow
    • 20040695 Epub 2009/12/31
    • Sanz C, Vazquez P, Blazquez C, Barrio PA, Alvarez Mdel M, Blazquez E. Signaling and biological effects of glucagon-like peptide 1 on the differentiation of mesenchymal stem cells from human bone marrow. American journal of physiology Endocrinology and metabolism. 2010;298(3):E634-43. Epub 2009/12/31. doi: ajpendo.00460.2009 [pii] doi: 10.1152/ajpendo.00460.2009 PMID: 20040695.
    • (2010) American Journal of Physiology Endocrinology and Metabolism , vol.298 , Issue.3 , pp. E634-E643
    • Sanz, C.1    Vazquez, P.2    Blazquez, C.3    Barrio, P.A.4    Alvarez Mdel, M.5    Blazquez, E.6
  • 17
    • 84855892759 scopus 로고    scopus 로고
    • New factors controlling the balance between osteoblastogenesis and adipogenesis
    • 21745614
    • Abdallah BM, Kassem M. New factors controlling the balance between osteoblastogenesis and adipogenesis. Bone. 2012;50(2):540-5. doi: 10.1016/j.bone.2011.06.030 PMID: 21745614.
    • (2012) Bone , vol.50 , Issue.2 , pp. 540-545
    • Abdallah, B.M.1    Kassem, M.2
  • 18
    • 79952191418 scopus 로고    scopus 로고
    • Wnt signalling mediates the cross-talk between bone marrow derived pre-adipocytic and pre-osteoblastic cell populations
    • 21211534
    • Taipaleenmaki H, Abdallah BM, Al Dahmash A, Saamanen AM, Kassem M. Wnt signalling mediates the cross-talk between bone marrow derived pre-adipocytic and pre-osteoblastic cell populations. Experimental cell research. 2011;317(6):745-56. doi: 10.1016/j.yexcr.2010.12.015 PMID: 21211534.
    • (2011) Experimental Cell Research , vol.317 , Issue.6 , pp. 745-756
    • Taipaleenmaki, H.1    Abdallah, B.M.2    Al Dahmash, A.3    Saamanen, A.M.4    Kassem, M.5
  • 20
    • 80053103834 scopus 로고    scopus 로고
    • Pro-bone and antifat effects of green tea and its polyphenol, epigallocatechin, in rat mesenchymal stem cells in vitro
    • 21877759
    • Ko CH, Siu WS, Wong HL, Shum WT, Fung KP, San Lau CB, et al. Pro-bone and antifat effects of green tea and its polyphenol, epigallocatechin, in rat mesenchymal stem cells in vitro. Journal of agricultural and food chemistry. 2011;59(18):9870-6. doi: 10.1021/jf202015t PMID: 21877759.
    • (2011) Journal of Agricultural and Food Chemistry , vol.59 , Issue.18 , pp. 9870-9876
    • Ko, C.H.1    Siu, W.S.2    Wong, H.L.3    Shum, W.T.4    Fung, K.P.5    San Lau, C.B.6
  • 21
    • 84878865789 scopus 로고    scopus 로고
    • Porous tantalum coatings prepared by vacuum plasma spraying enhance bmscs osteogenic differentiation and bone regeneration in vitro and in vivo
    • 23776648 Epub 2013/06/19, PubMed Central, PMCID: PMC3679049
    • Tang Z, Xie Y, Yang F, Huang Y, Wang C, Dai K, et al. Porous tantalum coatings prepared by vacuum plasma spraying enhance bmscs osteogenic differentiation and bone regeneration in vitro and in vivo. PLoSOne. 2013;8(6):e66263. Epub 2013/06/19. doi: 10.1371/journal.pone. 0066263PONE-D-13-04524 [pii]. PMID: 23776648; PubMed Central PMCID: PMC3679049.
    • (2013) PLoSOne , vol.8 , Issue.6 , pp. e66263
    • Tang, Z.1    Xie, Y.2    Yang, F.3    Huang, Y.4    Wang, C.5    Dai, K.6
  • 22
    • 23744498205 scopus 로고    scopus 로고
    • Myeloma cells block RUNX2/CBFA1 activity in human bone marrow osteoblast progenitors and inhibit osteoblast formation and differentiation
    • 15933061 Epub 2005/06/04 2004-12-4986
    • Giuliani N, Colla S, Morandi F, Lazzaretti M, Sala R, Bonomini S, et al. Myeloma cells block RUNX2/CBFA1 activity in human bone marrow osteoblast progenitors and inhibit osteoblast formation and differentiation. Blood. 2005;106(7):2472-83. Epub 2005/06/04. doi: 2004-12-4986 [pii] doi: 10.1182/blood-2004-12-4986 PMID: 15933061.
    • (2005) Blood , vol.106 , Issue.7 , pp. 2472-2483
    • Giuliani, N.1    Colla, S.2    Morandi, F.3    Lazzaretti, M.4    Sala, R.5    Bonomini, S.6
  • 23
    • 0031012411 scopus 로고    scopus 로고
    • Osteogenic differentiation of purified, cultureexpanded human mesenchymal stem cells in vitro
    • 9027589 Epub 1997/02/01 642<295::AID-JCB12>3.0.CO;2-I
    • Jaiswal N, Haynesworth SE, Caplan AI, Bruder SP. Osteogenic differentiation of purified, cultureexpanded human mesenchymal stem cells in vitro. J Cell Biochem. 1997;64(2):295-312. Epub 1997/02/01. doi: 10.1002/(SICI) 1097-4644 (199702) 64:2<295::AID-JCB12>3.0. CO;2-I [pii]. PMID: 9027589.
    • (1997) J Cell Biochem , vol.64 , Issue.2 , pp. 295-312
    • Jaiswal, N.1    Haynesworth, S.E.2    Caplan, A.I.3    Bruder, S.P.4
  • 24
    • 80052364465 scopus 로고    scopus 로고
    • Gsalpha enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice
    • 21804192 PubMed Central, PMCID: PMC3163961
    • Wu JY, Aarnisalo P, Bastepe M, Sinha P, Fulzele K, Selig MK, et al. Gsalpha enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice. The Journal of clinical investigation. 2011;121(9):3492-504. doi: 10.1172/JCI46406 PMID: 21804192; PubMed Central PMCID: PMC3163961.
    • (2011) The Journal of Clinical Investigation , vol.121 , Issue.9 , pp. 3492-3504
    • Wu, J.Y.1    Aarnisalo, P.2    Bastepe, M.3    Sinha, P.4    Fulzele, K.5    Selig, M.K.6
  • 26
    • 84863663100 scopus 로고    scopus 로고
    • Bone: Incretin hormones perceiveror receiver?
    • 22761607 PubMed Central, PMCID: PMC3385656
    • Dicembrini I, Mannucci E, Rotella CM. Bone: incretin hormones perceiveror receiver? Experimental diabetes research. 2012;2012:519784. doi: 10.1155/2012/519784 PMID: 22761607; PubMed Central PMCID: PMC3385656.
    • (2012) Experimental Diabetes Research , vol.2012 , pp. 519784
    • Dicembrini, I.1    Mannucci, E.2    Rotella, C.M.3
  • 27
    • 84897456623 scopus 로고    scopus 로고
    • Role of endogenous GLP-1 and its agonists in osteopenia and osteoporosis: But we little know until tried
    • 24527734
    • Papazafiropoulou A, Papanas N, Pappas S, Maltezos E. Role of endogenous GLP-1 and its agonists in osteopenia and osteoporosis: but we little know until tried. Current diabetes reviews. 2014;10(1):43-7. PMID: 24527734.
    • (2014) Current Diabetes Reviews , vol.10 , Issue.1 , pp. 43-47
    • Papazafiropoulou, A.1    Papanas, N.2    Pappas, S.3    Maltezos, E.4
  • 28
    • 84939877452 scopus 로고    scopus 로고
    • Risk of bone fractures associated with glucagon-like peptide-1 receptor agonists' treatment: A meta-analysis of randomized controlled trials
    • 25074632
    • Su B, Sheng H, Zhang M, Bu L, Yang P, Li L, et al. Risk of bone fractures associated with glucagon-like peptide-1 receptor agonists' treatment: a meta-analysis of randomized controlled trials. Endocrine. 2014. doi: 10.1007/s12020-014-0361-4 PMID: 25074632.
    • (2014) Endocrine
    • Su, B.1    Sheng, H.2    Zhang, M.3    Bu, L.4    Yang, P.5    Li, L.6
  • 29
    • 79952120270 scopus 로고    scopus 로고
    • Hyperglycemia impairs skeletogenesis from embryonic stem cells by affecting osteoblast and osteoclast differentiation
    • 20939707
    • Dienelt A, Zur Nieden NI. Hyperglycemia impairs skeletogenesis from embryonic stem cells by affecting osteoblast and osteoclast differentiation. Stem cells and development. 2011;20(3):465-74. doi: 10. 1089/scd.2010.0205 PMID: 20939707.
    • (2011) Stem Cells and Development , vol.20 , Issue.3 , pp. 465-474
    • Dienelt, A.1    Zur Nieden, N.I.2
  • 30
    • 43149104735 scopus 로고    scopus 로고
    • High d (+) glucose concentration inhibits RANKL-induced osteoclastogenesis
    • 18378205 PubMed Central, PMCID: PMC2696157
    • Wittrant Y, Gorin Y, Woodruff K, Horn D, Abboud HE, Mohan S, et al. High d (+) glucose concentration inhibits RANKL-induced osteoclastogenesis. Bone. 2008;42(6):1122-30. doi: 10.1016/j.bone.2008. 02.006 PMID: 18378205; PubMed Central PMCID: PMC2696157.
    • (2008) Bone , vol.42 , Issue.6 , pp. 1122-1130
    • Wittrant, Y.1    Gorin, Y.2    Woodruff, K.3    Horn, D.4    Abboud, H.E.5    Mohan, S.6
  • 31
    • 84881612495 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor agonist treatment reduces beta cell mass in normoglycaemic mice
    • 23771206
    • Ellenbroek JH, Tons HA, Westerouen Van Meeteren MJ, De Graaf N, Hanegraaf MA, Rabelink TJ, et al. Glucagon-like peptide-1 receptor agonist treatment reduces beta cell mass in normoglycaemic mice. Diabetologia. 2013;56(9):1980-6. doi: 10.1007/s00125-013-2957-2 PMID: 23771206.
    • (2013) Diabetologia , vol.56 , Issue.9 , pp. 1980-1986
    • Ellenbroek, J.H.1    Tons, H.A.2    Westerouen Van Meeteren, M.J.3    De Graaf, N.4    Hanegraaf, M.A.5    Rabelink, T.J.6
  • 32
    • 84862891810 scopus 로고    scopus 로고
    • Intensive glycemic control is not associated with fractures or falls in the ACCORD randomized trial
    • 22723583 PubMed Central, PMCID: PMC3379596
    • Schwartz AV, Margolis KL, Sellmeyer DE, Vittinghoff E, Ambrosius WT, Bonds DE, et al. Intensive glycemic control is not associated with fractures or falls in the ACCORD randomized trial. Diabetes care. 2012;35(7):1525-31. doi: 10.2337/dc11-2184 PMID: 22723583; PubMed Central PMCID: PMC3379596.
    • (2012) Diabetes Care , vol.35 , Issue.7 , pp. 1525-1531
    • Schwartz, A.V.1    Margolis, K.L.2    Sellmeyer, D.E.3    Vittinghoff, E.4    Ambrosius, W.T.5    Bonds, D.E.6
  • 33
    • 17744374566 scopus 로고    scopus 로고
    • Osteoblast-derived cells express functional glucose-dependent insulinotropic peptide receptors
    • 10698200
    • Bollag RJ, Zhong Q, Phillips P, Min L, Zhong L, Cameron R, et al. Osteoblast-derived cells express functional glucose-dependent insulinotropic peptide receptors. Endocrinology. 2000;141(3):1228-35. doi: 10.1210/endo.141.3.7366 PMID: 10698200.
    • (2000) Endocrinology , vol.141 , Issue.3 , pp. 1228-1235
    • Bollag, R.J.1    Zhong, Q.2    Phillips, P.3    Min, L.4    Zhong, L.5    Cameron, R.6
  • 34
    • 84904244581 scopus 로고    scopus 로고
    • Expression of glucagon-like peptide-1 receptor and glucosedependent insulinotropic polypeptide receptor is regulated by the glucose concentration in mouse osteoblastic MC3T3-E1 cells
    • 24866833
    • Aoyama E, Watari I, Podyma-Inoue KA, Yanagishita M, Ono T. Expression of glucagon-like peptide-1 receptor and glucosedependent insulinotropic polypeptide receptor is regulated by the glucose concentration in mouse osteoblastic MC3T3-E1 cells. International journal of molecular medicine. 2014;34(2):475-82. doi: 10.3892/ijmm.2014.1787 PMID: 24866833.
    • (2014) International Journal of Molecular Medicine , vol.34 , Issue.2 , pp. 475-482
    • Aoyama, E.1    Watari, I.2    Podyma-Inoue, K.A.3    Yanagishita, M.4    Ono, T.5
  • 35
    • 38549146030 scopus 로고    scopus 로고
    • The murine glucagon-like peptide-1 receptor is essential for control of bone resorption
    • 18039776 Epub 2007/11/28
    • Yamada C, Yamada Y, Tsukiyama K, Yamada K, Udagawa N, Takahashi N, et al. The murine glucagon-like peptide-1 receptor is essential for control of bone resorption. Endocrinology. 2008;149(2):574-9. Epub 2007/11/28. doi: en. 2007-1292 [pii] doi: 10.1210/en. 2007-1292 PMID: 18039776.
    • (2008) Endocrinology , vol.149 , Issue.2 , pp. 574-579
    • Yamada, C.1    Yamada, Y.2    Tsukiyama, K.3    Yamada, K.4    Udagawa, N.5    Takahashi, N.6
  • 36
    • 84884175131 scopus 로고    scopus 로고
    • Optimal bone mechanical and material properties require afunctional glucagon-like peptide-1 receptor
    • 23911987
    • Mabilleau G, Mieczkowska A, Irwin N, Flatt PR, Chappard D. Optimal bone mechanical and material properties require afunctional glucagon-like peptide-1 receptor. The Journal of endocrinology. 2013;219(1):59-68. doi: 10.1530/JOE-13-0146 PMID: 23911987.
    • (2013) The Journal of Endocrinology , vol.219 , Issue.1 , pp. 59-68
    • Mabilleau, G.1    Mieczkowska, A.2    Irwin, N.3    Flatt, P.R.4    Chappard, D.5
  • 38
    • 0030684749 scopus 로고    scopus 로고
    • Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
    • 9182763
    • Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, Deguchi K, et al. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell. 1997;89(5):755-64. PMID: 9182763.
    • (1997) Cell , vol.89 , Issue.5 , pp. 755-764
    • Komori, T.1    Yagi, H.2    Nomura, S.3    Yamaguchi, A.4    Sasaki, K.5    Deguchi, K.6
  • 39
    • 2142652189 scopus 로고    scopus 로고
    • PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors
    • 15067317 PubMed Central, PMCID: PMC362117
    • Akune T, Ohba S, Kamekura S, Yamaguchi M, Chung UI, Kubota N, et al. PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors. The Journal of clinical investigation. 2004;113(6):846-55. doi: 10.1172/JCI19900 PMID: 15067317; PubMed Central PMCID: PMC362117.
    • (2004) The Journal of Clinical Investigation , vol.113 , Issue.6 , pp. 846-855
    • Akune, T.1    Ohba, S.2    Kamekura, S.3    Yamaguchi, M.4    Chung, U.I.5    Kubota, N.6
  • 40
    • 79960883269 scopus 로고    scopus 로고
    • Receptors and effects of gut hormones in three osteoblastic cell lines
    • 21801348 Epub 2011/08/02, PubMed Central, PMCID: PMC3162581 1472-6793-11-12
    • Pacheco-Pantoja EL, Ranganath LR, Gallagher JA, Wilson PJ, Fraser WD. Receptors and effects of gut hormones in three osteoblastic cell lines. BMC Physiol. 2011;11:12. Epub 2011/08/02. doi: 1472-6793-11-12 [pii] doi: 10.1186/1472-6793-11-12 PMID: 21801348; PubMed Central PMCID: PMC3162581.
    • (2011) BMC Physiol. , vol.11 , pp. 12
    • Pacheco-Pantoja, E.L.1    Ranganath, L.R.2    Gallagher, J.A.3    Wilson, P.J.4    Fraser, W.D.5
  • 41
    • 77950228684 scopus 로고    scopus 로고
    • Glucagon-like Peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation
    • 20203154
    • Bjerre Knudsen L, Madsen LW, Andersen S, Almholt K, De Boer AS, Drucker DJ, et al. Glucagon-like Peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation. Endocrinology. 2010;151(4):1473-86. doi: 10.1210/en. 2009-1272 PMID: 20203154.
    • (2010) Endocrinology , vol.151 , Issue.4 , pp. 1473-1486
    • Bjerre Knudsen, L.1    Madsen, L.W.2    Andersen, S.3    Almholt, K.4    De Boer, A.S.5    Drucker, D.J.6
  • 42
    • 84871686739 scopus 로고    scopus 로고
    • GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE (-/-) mice
    • 23183176
    • Panjwani N, Mulvihill EE, Longuet C, Yusta B, Campbell JE, Brown TJ, et al. GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE (-/-) mice. Endocrinology. 2013;154(1):127-39. doi: 10.1210/en. 2012-1937 PMID: 23183176.
    • (2013) Endocrinology , vol.154 , Issue.1 , pp. 127-139
    • Panjwani, N.1    Mulvihill, E.E.2    Longuet, C.3    Yusta, B.4    Campbell, J.E.5    Brown, T.J.6


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