메뉴 건너뛰기




Volumn 10, Issue 1, 2014, Pages 43-47

Role of endogenous GLP-1 and its agonists in Osteopenia and osteoporosis: But we little know until tried

Author keywords

Bone metabolism; Fractures; GLP 1; Incretins; Type 2 diabetes mellitus

Indexed keywords

GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST;

EID: 84897456623     PISSN: 15733998     EISSN: 18756417     Source Type: Journal    
DOI: 10.2174/1573399810666140217114848     Document Type: Article
Times cited : (5)

References (28)
  • 1
    • 34548017660 scopus 로고    scopus 로고
    • Systematic review of type 1 and type 2 diabetes mellitus and risk of fracture
    • Janghorbani M, Van Dam RM, Willett WC, Hu FB. Systematic review of type 1 and type 2 diabetes mellitus and risk of fracture. Am J Epidemiol 2007; 166: 495-505.
    • (2007) Am J Epidemiol , vol.166 , pp. 495-505
    • Janghorbani, M.1    van Dam, R.M.2    Willett, W.C.3    Hu, F.B.4
  • 2
    • 48649095960 scopus 로고    scopus 로고
    • Rosiglitazone-associated fractures in type 2 diabetes: An Analysis from A Diabetes Outcome Progression Trial (ADOPT)
    • Kahn SE, Zinman B, Lachin JM, et al. Rosiglitazone-associated fractures in type 2 diabetes: an Analysis from A Diabetes Outcome Progression Trial (ADOPT). Diabetes Care 2008; 31: 845-851.
    • (2008) Diabetes Care , vol.31 , pp. 845-851
    • Kahn, S.E.1    Zinman, B.2    Lachin, J.M.3
  • 3
    • 0035403830 scopus 로고    scopus 로고
    • Iowa Women's Health Study. Type 1 and type 2 diabetes and incident hip fractures in postmenopausal women
    • Nicodemus KK, Folsom AR; Iowa Women's Health Study. Type 1 and type 2 diabetes and incident hip fractures in postmenopausal women. Diabetes Care 2001; 24: 1192-1197.
    • (2001) Diabetes Care , vol.24 , pp. 1192-1197
    • Nicodemus, K.K.1    Folsom, A.R.2
  • 4
    • 36949018942 scopus 로고    scopus 로고
    • Rosiglitazone stimulates adipogenesis and decreases osteoblastogenesis in human mesen-chymal stem cells
    • Benvenuti S, Cellai I, Luciani P, et al. Rosiglitazone stimulates adipogenesis and decreases osteoblastogenesis in human mesen-chymal stem cells. J Endocrinol Invest 2007; 30: RC26-RC30.
    • (2007) J Endocrinol Invest , vol.30
    • Benvenuti, S.1    Cellai, I.2    Luciani, P.3
  • 5
    • 33748740823 scopus 로고    scopus 로고
    • Risk of fracture in women with type 2 diabetes: The Women's Health Initiative Observational Study
    • Bonds DE, Larson JC, Schwartz AV, et al. Risk of fracture in women with type 2 diabetes: the Women's Health Initiative Observational Study. J Clin Endocrinol Metab 2006; 91: 3404-3410.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 3404-3410
    • Bonds, D.E.1    Larson, J.C.2    Schwartz, A.V.3
  • 7
    • 75149143476 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide: New advances
    • Asmar M, Holst JJ. Glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide: new advances. Curr Opin Endocrinol Diabetes Obes 2010; 17: 57-62.
    • (2010) Curr Opin Endocrinol Diabetes Obes , vol.17 , pp. 57-62
    • Asmar, M.1    Holst, J.J.2
  • 8
    • 77955611520 scopus 로고    scopus 로고
    • Therapeutic potential of the original incretin hormone glucose-dependent insulinotropic polypeptide: Diabetes, obesity, osteoporosis and Alzheimer's disease?
    • Irwin N, Gault V, Flatt PR. Therapeutic potential of the original incretin hormone glucose-dependent insulinotropic polypeptide: diabetes, obesity, osteoporosis and Alzheimer's disease? Expert Opin Investig Drugs 2010; 19: 1039-1048.
    • (2010) Expert Opin Investig Drugs , vol.19 , pp. 1039-1048
    • Irwin, N.1    Gault, V.2    Flatt, P.R.3
  • 9
    • 67349094596 scopus 로고    scopus 로고
    • Effect of GLP-1 treatment on bone turnover in normal, type 2 diabetic, and insulin-resistant states
    • Nuche-Berenguer B, Moreno P, Esbrit P, et al. Effect of GLP-1 treatment on bone turnover in normal, type 2 diabetic, and insulin-resistant states. Calcif Tissue Int 2009; 84: 453-4561.
    • (2009) Calcif Tissue Int , vol.84 , pp. 453-4561
    • Nuche-Berenguer, B.1    Moreno, P.2    Esbrit, P.3
  • 11
    • 0035947038 scopus 로고    scopus 로고
    • Glucose-dependent insuli- notropic peptide is an integrative hormone with osteotropic effects
    • Bollag RJ, Zhong Q, Ding KH, et al. Glucose-dependent insuli- notropic peptide is an integrative hormone with osteotropic effects. Mol Cell Endocrinol 2001; 177: 35-41.
    • (2001) Mol Cell Endocrinol , vol.177 , pp. 35-41
    • Bollag, R.J.1    Zhong, Q.2    Ding, K.H.3
  • 12
    • 34147142997 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic peptide-overexpressing transgenic mice have increased bone mass
    • Xie D, Zhong Q, Ding KH, et al. Glucose-dependent insulinotropic peptide-overexpressing transgenic mice have increased bone mass. Bone 2007; 40: 1352-1360.
    • (2007) Bone , vol.40 , pp. 1352-1360
    • Xie, D.1    Zhong, Q.2    Ding, K.H.3
  • 13
    • 41849094819 scopus 로고    scopus 로고
    • Impact of glucose-dependent insulinotropic peptide on age-induced bone loss
    • Ding KH, Shi XM, Zhong Q, et al. Impact of glucose-dependent insulinotropic peptide on age-induced bone loss. J Bone Miner Res 2008; 23: 536-543.
    • (2008) J Bone Miner Res , vol.23 , pp. 536-543
    • Ding, K.H.1    Shi, X.M.2    Zhong, Q.3
  • 15
    • 79954782586 scopus 로고    scopus 로고
    • GLP-1 and exendin-4 can reverse hyperlipidic-related osteopenia
    • Nuche-Berenguer B, Lozano D, Gutiérrez-Rojas I, et al. GLP-1 and exendin-4 can reverse hyperlipidic-related osteopenia. J Endocrinol 2011; 209: 203-210.
    • (2011) J Endocrinol , vol.209 , pp. 203-210
    • Nuche-Berenguer, B.1    Lozano, D.2    Gutiérrez-Rojas, I.3
  • 16
    • 84879221597 scopus 로고    scopus 로고
    • Exendin-4, a GLP-1 receptor agonist, prevents osteopnia by promoting bone formation and suppressing bone resorption in aged ovariectomized rats
    • Feb 20. [Epub ahead of print
    • Ma X, Meng J, Jia M, et al. Exendin-4, a GLP-1 receptor agonist, prevents osteopnia by promoting bone formation and suppressing bone resorption in aged ovariectomized rats. J Bone Miner Res 2013 Feb 20. [Epub ahead of print]
    • (2013) J Bone Miner Res
    • Ma, X.1    Meng, J.2    Jia, M.3
  • 17
    • 84875455404 scopus 로고    scopus 로고
    • Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes
    • Kim JY, Lee SK, Jo KJ, et al. Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes. Life Sci 2013; 92: 533-540.
    • (2013) Life Sci , vol.92 , pp. 533-540
    • Kim, J.Y.1    Lee, S.K.2    Jo, K.J.3
  • 18
    • 84868206397 scopus 로고    scopus 로고
    • The deleterious effect of bariatric surgery on cortical and trabecular bone density in the femurs of non-obese, type 2 diabetic Goto-Kakizaki rats
    • Pérez-Castrillón JL, Riancho JA, de Luis D, et al. The deleterious effect of bariatric surgery on cortical and trabecular bone density in the femurs of non-obese, type 2 diabetic Goto-Kakizaki rats. Obes Surg 2012; 22: 1755-1760.
    • (2012) Obes Surg , vol.22 , pp. 1755-1760
    • Pérez-Castrillón, J.L.1    Riancho, J.A.2    de Luis, D.3
  • 19
    • 10744224629 scopus 로고    scopus 로고
    • Role of gastrointestinal hormones in postprandial reduction of bone resorption
    • Henriksen DB, Alexandersen P, Bjarnason NH, et al. Role of gastrointestinal hormones in postprandial reduction of bone resorption. J Bone Miner Res 2003; 18: 2180-2189.
    • (2003) J Bone Miner Res , vol.18 , pp. 2180-2189
    • Henriksen, D.B.1    Alexandersen, P.2    Bjarnason, N.H.3
  • 20
    • 79951870602 scopus 로고    scopus 로고
    • Exenatide treatment did not affect bone mineral density despite body weight reduction in patients with type 2 diabetes
    • Bunck MC, Eliasson B, Cornér A, et al. Exenatide treatment did not affect bone mineral density despite body weight reduction in patients with type 2 diabetes. Diabetes Obes Metab 2011; 13: 374-377.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 374-377
    • Bunck, M.C.1    Eliasson, B.2    Cornér, A.3
  • 21
    • 70349279885 scopus 로고    scopus 로고
    • Four-month treatment with GLP-2 significantly increases hip BMD: A randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD
    • Henriksen DB, Alexandersen P, Hartmann B, et al. Four-month treatment with GLP-2 significantly increases hip BMD: a randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD. Bone 2009; 45: 833-842.
    • (2009) Bone , vol.45 , pp. 833-842
    • Henriksen, D.B.1    Alexandersen, P.2    Hartmann, B.3
  • 22
    • 47949132796 scopus 로고    scopus 로고
    • Reduction in bone resorption by exogenous glucagon-like peptide-2 administration requires an intact gastrointestinal tract
    • Gottschalck IB, Jeppesen PB, Holst JJ, Henriksen DB. Reduction in bone resorption by exogenous glucagon-like peptide-2 administration requires an intact gastrointestinal tract. Scand J Gastroen-terol 2008; 43: 929-937.
    • (2008) Scand J Gastroen-terol , vol.43 , pp. 929-937
    • Gottschalck, I.B.1    Jeppesen, P.B.2    Holst, J.J.3    Henriksen, D.B.4
  • 23
    • 77956496046 scopus 로고    scopus 로고
    • Presence of a functional receptor for GLP-1 in osteoblastic cells, independent of the cAMP-linked GLP-1 receptor
    • Nuche-Berenguer B, Portal-Núñez S, Moreno P, et al. Presence of a functional receptor for GLP-1 in osteoblastic cells, independent of the cAMP-linked GLP-1 receptor. J Cell Physiol 2010; 225: 585-592.
    • (2010) J Cell Physiol , vol.225 , pp. 585-592
    • Nuche-Berenguer, B.1    Portal-Núñez, S.2    Moreno, P.3
  • 25
    • 38549146030 scopus 로고    scopus 로고
    • The murine glucagon-like peptide-1 receptor is essential for control of bone resorption
    • Yamada C, Yamada Y, Tsukiyama K, et al. The murine glucagon-like peptide-1 receptor is essential for control of bone resorption. Endocrinology 2008; 149: 574-579.
    • (2008) Endocrinology , vol.149 , pp. 574-579
    • Yamada, C.1    Yamada, Y.2    Tsukiyama, K.3
  • 26
    • 84864285795 scopus 로고    scopus 로고
    • Management of hy-perglycaemia in type 2 diabetes: A patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
    • Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hy-perglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia 2012; 55: 1577-1596.
    • (2012) Diabetologia , vol.55 , pp. 1577-1596
    • Inzucchi, S.E.1    Bergenstal, R.M.2    Buse, J.B.3
  • 27
    • 84881343544 scopus 로고    scopus 로고
    • Antidiabetic treatment: Though lovers be lost, love shall not
    • N. Papanas, E. Maltezos. Antidiabetic treatment: Though lovers be lost, love shall not. World J Diabetes 2012; 3: 158-160.
    • (2012) World J Diabetes , vol.3 , pp. 158-160
    • Papanas, N.1    Maltezos, E.2
  • 28
    • 84897470545 scopus 로고    scopus 로고
    • st October
    • st October 2013.
    • (2013)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.