The roles of IP3 receptor in energy metabolic pathways and reactive oxygen species homeostasis revealed by metabolomic and biochemical studies

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1853, Issue 11, 2015, Pages 2937-2944

  Wen, He ^a   Xu, Wen Jun ^a   Jin, Xing ^a   Oh, Sehyun ^a   Phan, Chau Hong Duc ^a   Song, Jayoung ^a   Lee, Sang Kook ^a   Park, Sunghyouk ^a  

^a Seoul National University   (South Korea)

Author keywords

DT40; Energy metabolism; IP3R; Metabolomics; ROS

Indexed keywords

ADENYLATE KINASE; CALCIUM CHANNEL; CATALASE; GLUTATHIONE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; MANGANESE SUPEROXIDE DISMUTASE; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUPEROXIDE DISMUTASE;

ARTICLE; BIOCHEMICAL ANALYSIS; CELL GROWTH; CELL LINE; ENERGY METABOLISM; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; GROWTH RATE; HOMEOSTASIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLIC REGULATION; METABOLOMICS; NUCLEAR MAGNETIC RESONANCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; GENE SILENCING; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY;

AMP-ACTIVATED PROTEIN KINASES; CELL LINE; ENERGY METABOLISM; GENE KNOCKDOWN TECHNIQUES; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; NADP; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 84941308774     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2015.07.020     Document Type: Article

References (38)

1. 2+ release channels. Physiol. Rev. 2007, 87:593-658.
2. Ivanova H., Vervliet T., Missiaen L., Parys J.B., De Smedt H., Bultynck G. Inositol 1,4,5-trisphosphate receptor-isoform diversity in cell death and survival. Biochim. Biophys. Acta 2014, 1843:2164-2183.
3. Nakagawa T., Okano H., Furuichi T., Aruga J., Mikoshiba K. The subtypes of the mouse inositol 1,4,5-trisphosphate receptor are expressed in a tissue-specific and developmentally specific manner. Proc. Natl. Acad. Sci. U. S. A. 1991, 88:6244-6248.
4. 2+-leak channel: cell biological and pathological consequences. Biol. Cell. 2006, 98:1-14.
5. 2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl. Cell Death Differ. 2012, 19:295-309.
6. Iwasa H., Yu S., Xue J., Driscoll M. Novel EGF pathway regulators modulate C. elegans healthspan and lifespan via EGF receptor, PLC-gamma, and IP3R activation. Aging Cell 2010, 9:490-505.
7. Wang Y., Li G., Goode J., Paz J.C., Ouyang K., Screaton R., Fischer W.H., Chen J., Tabas I., Montminy M. Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes. Nature 2012, 485:128-132.
8. Decuypere J.P., Bultynck G., Parys J.B. A dual role for Ca(2+) in autophagy regulation. Cell Calcium 2011, 50:242-250.
9. Winding P., Berchtold M.W. The chicken B cell line DT40: a novel tool for gene disruption experiments. J. Immunol. Methods 2001, 249:1-16.
10. Taylor C.W., Rahman T., Tovey S.C., Dedos S.G., Taylor E.J., Velamakanni S. IP3 receptors: some lessons from DT40 cells. Immunol. Rev. 2009, 231:23-44.
11. Sugawara H., Kurosaki M., Takata M., Kurosaki T. Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor. EMBO J. 1997, 16:3078-3088.
12. Dellis O., Dedos S.G., Tovey S.C., Taufiq Ur R., Dubel S.J., Taylor C.W. Ca2+ entry through plasma membrane IP3 receptors. Science 2006, 313:229-233.
13. Guillemette J., Caron A.Z., Regimbald-Dumas Y., Arguin G., Mignery G.A., Boulay G., Guillemette G. Expression of a truncated form of inositol 1,4,5-trisphosphate receptor type III in the cytosol of DT40 triple inositol 1,4,5-trisphosphate receptor-knockout cells. Cell Calcium 2005, 37:97-104.
14. Vicencio J.M., Ortiz C., Criollo A., Jones A.W., Kepp O., Galluzzi L., Joza N., Vitale I., Morselli E., Tailler M., Castedo M., Maiuri M.C., Molgo J., Szabadkai G., Lavandero S., Kroemer G. The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1. Cell Death Differ. 2009, 16:1006-1017.
15. Khan M.T., Joseph S.K. Role of inositol trisphosphate receptors in autophagy in DT40 cells. J. Biol. Chem. 2010, 285:16912-16920.
16. 2+ transfer to mitochondria. Cell 2010, 142:270-283.
17. Bansaghi S., Golenar T., Madesh M., Csordas G., RamachandraRao S., Sharma K., Yule D.I., Joseph S.K., Hajnoczky G. Isoform- and species-specific control of inositol 1,4,5-trisphosphate (IP3) receptors by reactive oxygen species. J. Biol. Chem. 2014, 289:8170-8181.
18. Patti G.J., Yanes O., Siuzdak G. Innovation: metabolomics: the apogee of the omics trilogy. Nat. Rev. Mol. Cell Biol. 2012, 13:263-269.
19. Wang T.J., Larson M.G., Vasan R.S., Cheng S., Rhee E.P., McCabe E., Lewis G.D., Fox C.S., Jacques P.F., Fernandez C., O'Donnell C.J., Carr S.A., Mootha V.K., Florez J.C., Souza A., Melander O., Clish C.B., Gerszten R.E. Metabolite profiles and the risk of developing diabetes. Nat. Med. 2011, 17:448-453.
20. Cho H.R., Wen H., Ryu Y.J., An Y.J., Kim H.C., Moon W.K., Han M.H., Park S., Choi S.H. An NMR metabolomics approach for the diagnosis of leptomeningeal carcinomatosis. Cancer Res. 2012, 72:5179-5187.
21. Vermeer L.S., Fruhwirth G.O., Pandya P., Ng T., Mason A.J. NMR metabolomics of MTLn3E breast cancer cells identifies a role for CXCR4 in lipid and choline regulation. J. Proteome Res. 2012, 11:2996-3003.
22. An Y.J., Xu W.J., Jin X., Wen H., Kim H., Lee J., Park S. Metabotyping of the C. elegans sir-2.1 mutant using in vivo labeling and (13)C-heteronuclear multidimensional NMR metabolomics. ACS Chem. Biol. 2012, 7:2012-2018.
23. Kwon H.N., Kim M., Wen H., Kang S., Yang H.J., Choi M.J., Lee H.S., Choi D., Park I.S., Suh Y.J., Hong S.S., Park S. Predicting idiopathic toxicity of cisplatin by a pharmacometabonomic approach. Kidney Int. 2011, 79:529-537.
24. 1H nuclear magnetic resonance (NMR) metabolomics approach combined with orthogonal projections to latent structure-discriminant analysis as an efficient tool for discriminating between Korean and Chinese herbal medicines. J. Agric. Food Chem. 2008, 56:11589-11595.
25. Bylesjo M., Rantalainen M., Cloarec O., Nicholson J., Holmes E., Trygg J. OPLS discriminant analysis: combining the strengths of PLS-DA and SIMCA classification. J. Chemom. 2006, 20:341-351.
26. Wen H., Yoo S.S., Kang J., Kim H.G., Park J.S., Jeong S., Lee J.I., Kwon H.N., Kang S., Lee D.H., Park S. A new NMR-based metabolomics approach for the diagnosis of biliary tract cancer. J. Hepatol. 2010, 52:228-233.
27. Schneider C.A., Rasband W.S., Eliceiri K.W. NIH Image to ImageJ: 25years of image analysis. Nat. Methods 2012, 9:671-675.
28. Warburg O. On the origin of cancer cells. Science 1956, 123:309-314.
29. Li L., Chen Y., Gibson S.B. Starvation-induced autophagy is regulated by mitochondrial reactive oxygen species leading to AMPK activation. Cell. Signal. 2013, 25:50-65.
30. Scherz-Shouval R., Shvets E., Fass E., Shorer H., Gil L., Elazar Z. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J. 2007, 26:1749-1760.
31. Neufeld T.P. Autophagy and cell growth-the yin and yang of nutrient responses. J. Cell Sci. 2012, 125:2359-2368.
32. Tornroth-Horsefield S., Neutze R. Opening and closing the metabolite gate. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:19565-19566.
33. Hardie D.G., Hawley S.A. AMP-activated protein kinase: the energy charge hypothesis revisited. Bioessays 2001, 23:1112-1119.
34. Liu X., Zhang C.C., Liu Z., Wei L., Liu Y.J., Yu J., Sun L.X. LC-based targeted metabolomics analysis of nucleotides and identification of biomarkers associated with chemotherapeutic drugs in cultured cell models. Anti-Cancer Drugs 2014, 25:690-703.
35. Hristina K., Langerholc T., Trapecar M. Novel metabolic roles of l-arginine in body energy metabolism and possible clinical applications. J. Nutr. Health Aging 2014, 18:213-218.
36. Oakhill J.S., Steel R., Chen Z.P., Scott J.W., Ling N., Tam S., Kemp B.E. AMPK is a direct adenylate charge-regulated protein kinase. Science 2011, 332:1433-1435.
37. Periasamy M., Kalyanasundaram A. SERCA pump isoforms: their role in calcium transport and disease. Muscle Nerve 2007, 35:430-442.
38. Smith I.C., Bombardier E., Vigna C., Tupling A.R. ATP consumption by sarcoplasmic reticulum Ca(2)(+) pumps accounts for 40-50% of resting metabolic rate in mouse fast and slow twitch skeletal muscle. PLoS One 2013, 8:e68924.