Steroidal saponins from the roots and rhizomes of tupistra chinensis

Molecules

Volumn 20, Issue 8, 2015, Pages 13659-13669

  Li, Yuze ^a   Wang, Xin ^b   He, Hao ^c   Zhang, Dongdong ^a   Jiang, Yi ^a   Yang, Xinjie ^a   Wang, Fei ^a   Tang, Zhishu ^a   Song, Xiaomei ^a   Yue, Zhenggang ^a  

^a SHAANXI UNIVERSITY OF CHINESE MEDICINE   (China)

^b First Hosp of Xi'an Jiaotong Univ   (China)

^c XI'AN MEDICAL UNIVERSITY   (China)

Author keywords

Cytotoxic activity; Steroidal saponins; Structure identification; Tupistra chinensis

Indexed keywords

ANTINEOPLASTIC AGENT; SAPONIN;

ANGIOSPERM; CELL LINE; CHEMISTRY; DRUG SCREENING; HUMAN; ISOLATION AND PURIFICATION; RHIZOME;

ANGIOSPERMS; ANTINEOPLASTIC AGENTS; CELL LINE; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; RHIZOME; SAPONINS;

EID: 84941249082     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules200813659     Document Type: Article

References (19)

1. Song, X.; Liu, H. Research and Application of "Qi-Medicines" in Taibai Mountains; People's Medical Publishing House: Beijing, China, 2011.
2. Wu, X.; Fan, J.; Ouyang, Z.; Ning, R.; Guo, W.; Shen, Y.; Sun, Y.; Xu, Q. Tupistra chinensis extract attenuates murine fulminant hepatitis with multiple targets against activated T lymphocytes. J. Pharm. Pharmacol. 2014, 66, 453-465.
3. Pan, Z.; Li, Y.; Liu, J.; Ning, D.; Li, D.; Wu, X.; Wen, Y. A cytotoxic cardenolide and a saponin from the rhizomes of Tupistra chinensis. Fitoterapia 2012, 83, 1489-1493.
4. Cai, J.; Zhu, Z.; Yu, C.; Lei, L.; Wu, S. Saponin from Tupistra chinensis Baker inhibits mouse sarcoma S-180 cell proliferation in vitro and implanted solid tumor growth in mice. J. South. Med. Univ. 2007, 27, 188-190.
5. Li, Q.; Zou, K.; Wang, Y. Experimental study on vitro anti-tumor action of "Kai-Kou-Jian" extract. Chin. J. Ethnomed. Ethnopharm. 2007, 86, 164-167.
6. Liu, C.; Guo, Z.; Xue, Y.; Cheng, J.; Huang, N.; Zhou, Y.; Cheng, F.; Zou, K. Five new furostanol saponins from the rhizomes of Tupistra chinensis. Fitoterapia 2012, 83, 323-328.
7. Huang, W. Zhang, H. Zou, K. Chen, J. Li, X. Liu, C. Huang, N. Total saponins of Tupistra chinensis induces apoptosis in A549 cells. Neoplasma 2012, 59, 613-621.
8. Song, X.; Li, Y.; Zhang, D.; Jiang, Y.; Wang, W.; Song, B.; Tang, Z.; Cui, J.; Yue, Z. Two new spirostanol saponins from the the roots and rhizomes of Tupistra chinensis. Phytochem. Lett. 2015, 13, 6-10.
9. Chai, J.; Song, X.; Wang, X.; Mei, Q.; Li, Z.; Cui, J.; Tang, Z.; Yue, Z. Two new compounds from the roots and rhizomes of Trillium tschonoskii. Phytochem. Lett. 2014, 10, 113-117.
10. Li, H.; Pan, X.; Mei, Q.; Song, X.; Pei, Y.; Yue, Z. Isolation and identification of chemical constituents from root and rhizoma of Trillium tschonoskii Maxim. J. Shenyang Pharm. Univ. 2013, 30, 509-516.
11. Yue, Z.; Qin, H.; Li, Y.; Sun, Y.; Wang, Z.; Yang, T.; Liu, L.; Wang, M.; Feng, F.; Mei, Q. Chemical constituents of the root of Jasminum giraldii. Molecules 2013, 18, 4766-4775.
12. Hudson, C.; Dale, J. Studies on the forms of D-glucose and their mutarotation. J. Am. Chem. Soc. 1917, 39, 320-328.
13. Zhang, X.; Chen, C.; Yang, J.; Ni, W.; Liu, H. New minor spirostane glycosides from Ypsilandra thibetica. Helv. Chim. Acta 2012, 95, 1087-1093.
14. Yan, W.; Ohtani, K.; Kasai, R.; Yamasaki, K. Steroidal saponins from fruits of Tribulus terrestris. Phytochemistry 1996, 42, 1417-1422.
15. Liu, C.; Guo, Z.; Xue, Y.; Zhang, H.; Zhang, H.; Zou, K.; Huang, N. Tupisteroide A-C, three new polyhydroxylated steroidal constituents from the roots of Tupistra chinensis. Magn. Reson. Chem. 2012, 50, 320-324.
16. Xu, L.; Zou, K.; Wang, J.; Wu, J.; Zhou, Y.; Dan, F.; Yang, J. New polyhydroxylated furostanol saponins with inhibitory action against NO production from Tupistra chinensis Rhizomes. Molecules 2007, 12, 2029-2037.
17. Li, Y.; Fan, L.; Sun, Y.; Miao, X.; Zhang, F.; Meng, J.; Han, J.; Zhang, D.; Zhang, R.; Yue, Z.; et al. Paris saponin VII from trillium tschonoskii reverses multidrug resistance of adriamycin-resistant MCF-7/ADR cells via P-glycoprotein inhibition and apoptosis augmentation. J. Ethnopharmcol. 2014, 154, 728-734.
18. Li, Y.; Sun, Y.; Fan, L.; Zhang, F.; Meng, J.; Han, J.; Guo, X.; Zhang, D.; Zhang, R.; Yue, Z.; et al. Paris saponin VII inhibits growth of colorectal cancer cells through Ras signaling pathway. Biochem. Pharmacol. 2014, 88, 150-157.
19. Pan, W.; Chang, F.; Wei, L.; Wu, Y. New flavans, spirostanol sapogenins, and a pregnane genin from Tupistra chinensis and their cytotoxicity. J. Nat. Prod. 2003, 66, 161-168.